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List of works by Peter Lichter

3D geometry-based quantification of colocalizations in multichannel 3D microscopy images of human soft tissue tumors

scientific article published on 17 June 2010

A biobank of patient-derived pediatric brain tumor models

scientific article published on 22 October 2018

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling

scientific article published in June 2006

A cell-based model system links chromothripsis with hyperploidy

scientific article published on 28 September 2015

A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

scientific article

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors

scientific article published on April 2011

A mammalian microRNA expression atlas based on small RNA library sequencing

scientific article

A novel cloning strategy for one-step assembly of multiplex CRISPR vectors

scientific article published in Scientific Reports

Abstract 3089: (Epi)genetic profiling enables molecular re-classification of CNS-primitive neuroectodermal tumors

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Accumulation of genomic aberrations during clinical progression of medulloblastoma

scientific article published on 15 August 2008

Acromegaly Caused by Secretion of Growth Hormone by a Non-Hodgkin's Lymphoma

Activation of MAP kinase signaling through ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC).

scientific article published on May 2008

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

scientific article published on 27 January 2016

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

scientific article

Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia

scientific article published on 17 January 2006

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

scientific article published on 17 May 2010

Adult medulloblastoma comprises three major molecular variants.

scientific article

After 50 years: Future challenges in publishing cancer research

scientific article

Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer

All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia

scientific article published on January 2010

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

scholarly article

An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice

scientific article

Analysis of 11q22-q23 deletion target genes in B-cell chronic lymphocytic leukaemia: evidence for a pathogenic role of NPAT, CUL5, and PPP2R1B.

scientific article

Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphoma

scientific article published on 24 April 2006

Antiapoptotic function of charged multivesicular body protein 5: A potentially relevant gene in acute myeloid leukemia ⬇️

scientific article published on October 19, 2010

Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma

scientific article published on 7 March 2007

Assembly and mobility of exon-exon junction complexes in living cells

scientific article published on 26 March 2009

Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization

scientific article published on 18 September 2006

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

scientific article published on March 1, 2011

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

scientific article

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH-like DNA hypermethylation

scientific article published in Nature

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

scientific article published in Nature

Author Correction: The landscape of genomic alterations across childhood cancers

scientific article published in Nature

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations

scientific article

Automated screening for genomic imbalances using matrix-based comparative genomic hybridization

scientific article published in January 2002

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

scientific article published on 23 June 2013

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

scientific article published on 8 November 2017

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

scientific article published on May 2008

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

scientific article

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience

scientific article published on 22 April 2019

Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype

scientific article

CD24 Ala57Val polymorphism predicts pathologic complete response to sequential anthracycline- and taxane-based neoadjuvant chemotherapy for primary breast cancer

scientific article published on 30 September 2011

CITED4 gene silencing in colorectal cancer cells modulates adherens/tight junction gene expression and reduces cell proliferation

scientific article published on 5 August 2015

Candidate genes for cross-resistance against DNA-damaging drugs.

scientific article published on November 2002

Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.

scientific article published on January 2005

Capture and Amplification by Tailing and Switching (CATS). An ultrasensitive ligation-independent method for generation of DNA libraries for deep sequencing from picogram amounts of DNA and RNA

scientific article

Characterization of a nuclear compartment shared by nuclear bodies applying ectopic protein expression and correlative light and electron microscopy

scientific article published in February 2005

Characterization of nuclear compartments identified by ectopic markers in mammalian cells with distinctly different karyotype

scientific article

Chromothripsis in cancer cells: An update

scientific article published on 11 October 2015

Claes Lundsteen—in Memoriam

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.

scientific article

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

scientific article published on 01 August 2007

Clonal heterogeneity in childhood myelodysplastic syndromes--challenge for the detection of chromosomal imbalances by array-CGH

scientific article published on 01 October 2010

Comparative expressed sequence hybridization detects recurrent patterns of altered sequence expression in oral squamous cell carcinoma

scientific article published on 01 August 2010

Comparative gene mapping in cattle, Indian muntjac, and Chinese muntjac by fluorescence in situ hybridization

scientific article published on 19 February 2008

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

scientific article

Comparative sequence and expression analyses of four mammalian VPS4 genes

scientific article (publication date: 13 February 2003)

Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation

scientific article published on 27 December 2018

Comprehensive analysis of genomic alterations in gliosarcoma and its two tissue components

scientific article published on August 2002

Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH.

scientific article

Conflicts of interest: the responsibility of the authors and editors of the International Journal of Cancer

scientific article published in June 2006

Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease

Copy number gains on 22q13 in adenoid cystic carcinoma of the salivary gland revealed by comparative genomic hybridization and tissue microarray analysis

scientific article published on 01 May 2005

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article published in Nature

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies

scientific article

Cytogenetic and molecular genetic analyses of giant cell glioblastoma multiforme reveal distinct profiles in giant cell and non-giant cell subpopulations

scientific article published on 01 May 2007

Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes

scientific article

DIPG-22. IDENTIFICATION OF THERAPEUTIC TARGETS IN DIPGS USING LARGE-SCALE RNAI SCREENING.

scientific article published on 31 May 2017

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

scientific article

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

scientific article published on 18 January 2016

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

scientific article

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

scientific article

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

scientific article

Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization

scientific article

Development of a mantle cell lymphoma in an ATM heterozygous woman after occupational exposure to ionising radiation and somatic mutation of the second allele

scientific article

Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland.

scientific article published on October 2005

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma

scientific article published on 10 May 2013

Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors

scientific article published on 23 February 2011

Differentiation therapy exerts antitumor effects on stem-like glioma cells

scientific article published on 4 May 2010

Diffusion-limited compartmentalization of mammalian cell nuclei assessed by microinjected macromolecules ⬇️

scientific article published on October 1, 2003

Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Distinct chromosomal imbalances in pleomorphic and in high-grade dedifferentiated liposarcomas

scientific article

Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype

scientific article

Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes

scientific article

Distinct site-specific oncoprotein overexpression in head and neck squamous cell carcinoma: a tissue microarray analysis

scientific article published on 01 September 2003

Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia

scientific article

Doxorubicin/Pemetrexed Followed by Docetaxel Versus Doxorubicin/Cyclophosphamide Followed by Docetaxel as Neoadjuvant Treatment for Early-Stage Breast Cancer: A Randomized Phase II Trial

scientific article published in April 2007

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article (publication date: 29 January 2012)

Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets

scientific article published on 2 December 2010

Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line

scientific article

EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS.

scientific article published on 21 April 2015

EPEN-06. YAP1 SUBGROUP SUPRATENTORIAL EPENDYMOMA REQUIRES TEAD AND NUCLEAR FACTOR I-MEDIATED TRANSCRIPTIONAL PROGRAMS FOR TUMORIGENESIS

scientific article published on 23 April 2019

EPIG-04THE CHROMATIN LANDSCAPE OF MEDULLOBLASTOMA.

scientific article

EPN-34EPIGENOMIC ANALYSIS OF EPENDYMAL TUMORS IDENTIFIES SUBGROUP SPECIFIC ENHANCERS CONTROLLING DISTINCT REGULATORY CIRCUITRIES.

scientific article published on 30 May 2016

Effective transcriptome amplification for expression profiling on sense-oriented oligonucleotide microarrays

scientific article

Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data ⬇️

scientific article

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas

scientific article published on 25 August 2005

Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity

scientific article

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

scientific article

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

scientific article

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

scientific article

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 7 January 2016

Erratum: Corrigendum: Signatures of mutational processes in human cancer

scientific article published in Nature

Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma.

scientific article

Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma

scientific article

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

scientific article published on February 2008

Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes

scientific article

Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes

scientific article published on 02 May 2005

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia

scientific article

Experimental evidence for the influence of molecular crowding on nuclear architecture

scientific article published on 12 April 2007

Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia ⬇️

scientific article published on December 6, 2011

Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma

scientific article published in April 2007

Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation

scientific article published on 6 March 2012

Extracellular vesicles in chronic lymphocytic leukemia ⬇️

scientific article published on August 1, 2013

FACT--a framework for the functional interpretation of high-throughput experiments

scientific article

FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome

scholarly article by Bärbel Felder et al published 13 April 2009 in American Journal of Medical Genetics

FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

scientific article

Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.

scientific article published on 21 April 2010

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas

scientific article

Frequent high telomerase reverse transcriptase expression in primary oral squamous cell carcinoma

scientific article published on 01 May 2007

Functional screening for proapoptotic genes by reverse transfection cell array technology

scientific article published on 28 February 2006

GE-23ENHANCER HIJACKING ACTIVATES GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.

scientific article published in November 2014

GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS

scientific article published on 23 April 2019

Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma

scientific article published on 2 January 2003

Gene Expression Patterns in Ependymomas Correlate with Tumor Location, Grade, and Patient Age ⬇️

scientific article published on November 1, 2003

Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia

scientific article

Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes

scientific article published on 01 March 2004

Gene expression signature predicting pathologic complete response with gemcitabine, epirubicin, and docetaxel in primary breast cancer

scientific article published in April 2006

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial

scientific article published on 20 March 2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

scientific article

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP.

scientific article published on 15 April 2013

Genomic DNA-chip hybridization in t(11;14)-positive mantle cell lymphomas shows a high frequency of aberrations and allows a refined characterization of consensus regions

scientific article published on 13 April 2004

Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes

scientific article published on July 2004

Genomic aberrations in mantle cell lymphoma detected by interphase fluorescence in situ hybridization. Incidence and clinicopathological correlations

scientific article published on 26 March 2008

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

scientific article published on 27 October 2009

Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma

scientific article

Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts

scientific article published on 29 May 2014

Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One

scientific article published on 01 January 2003

Germline Elongator mutations in Sonic Hedgehog medulloblastoma

scientific article published on 01 April 2020

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

scientific article published on 18 December 2020

Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 22 October 2015

HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma

scientific article published on 20 May 2003

Hardware and software requirements for quantitative analysis of comparative genomic hybridization

article

Hidden gene amplifications in aggressive B-cell non-Hodgkin lymphomas detected by microarray-based comparative genomic hybridization

scientific article published in March 2003

High survivin expression is associated with favorable outcome in advanced primary oral squamous cell carcinoma after radiation therapy

scientific article published on 01 February 2007

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

scientific article published on 30 April 2009

High-resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histologic and genetic subgroups of invasive breast cancer

scientific article

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

scientific article published on 19 October 2015

Histone acetylation increases chromatin accessibility

scientific article published on 29 November 2005

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

scientific article published on February 2003

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

scientific article published in October 2012

Hypermutation of the inactive X chromosome is a frequent event in cancer

scientific article published on 17 October 2013

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing.

scientific article

IGF2 knockdown in two colorectal cancer cell lines decreases survival, adhesion and modulates survival-associated genes

scientific article published on 23 June 2016

IJC 2016

scientific article published on 01 January 2016

Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma

scientific article

Identification of novel AP-1 target genes in fibroblasts regulated during cutaneous wound healing.

scientific article

Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling

scientific article

In situ hybridization and detection using nonisotopic probes

scientific article published in July 2007

In situ hybridization to metaphase chromosomes and interphase nuclei

scientific article published in May 2005

In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains

scientific article published on 23 January 2006

Independent molecular development of metachronous glioblastomas with extended intervening recurrence-free interval.

scientific article published in October 2003

Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2 ⬇️

scientific article published on December 6, 2010

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

scientific article published on 10 July 2014

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

scientific article published on 10 March 2015

Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

scientific article published on 17 December 2013

International network of cancer genome projects

scientific article

Internationales Krebsgenomkonsortium (ICGC)

article

Investigation of nuclear architecture with a domain-presenting expression system

scientific article published on 01 October 2002

Isochromosome breakpoints on 17p in medulloblastoma are flanked by different classes of DNA sequence repeats

scientific article (publication date: 2006)

JunB is required for endothelial cell morphogenesis by regulating core-binding factor beta

scientific article

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

scientific article

Kinome-wide shRNA screen identifies the receptor tyrosine kinase AXL as a key regulator for mesenchymal glioblastoma stem-like cells

scientific article

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling

scientific article published on 14 April 2016

LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells

scientific article published on 30 August 2012

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)

scientific article published on 16 November 2012

Lenalidomide reduces survival of chronic lymphocytic leukemia cells in primary cocultures by altering the myeloid microenvironment ⬇️

scientific article published on January 24, 2013

LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 07 September 2020

Local gene density predicts the spatial position of genetic loci in the interphase nucleus

article

Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma

scientific article published on 20 May 2015

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

scientific article published on 20 August 2016

MAPK pathway activation in pilocytic astrocytoma

scientific article

MB-08MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.

scientific article published on 21 April 2015

MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07)

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.

scientific article published in July 2014

MPTH-15MOLECULAR RECLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS INTO WELL-KNOWN AND NOVEL TUMOR ENTITIES.

scientific article

MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema

scientific article

Macromolecular crowding and its potential impact on nuclear function

scientific article published on 30 July 2008

Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks

scientific article

Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.

scientific article

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.

scientific article published on 22 November 2013

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

scientific article (publication date: 22 July 2012)

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

scientific article published on 05 April 2016

Medulloblastomics: the end of the beginning

scientific article published on December 2012

MicroRNA profiling of primary high-grade soft tissue sarcomas

scientific article

MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma

scientific article published on 2 December 2011

Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status

scientific article published on 01 October 2004

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma

scientific article published on 01 June 2002

Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression

scientific article

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status

article

Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.

scientific article published in May 2004

Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments.

scientific article

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

scientific article

Molecular characterization of AML with ins(21;8)(q22;q22q22) reveals similarity to t(8;21) AML.

scientific article published on January 2011

Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

scientific article published on 22 March 2018

Molecular classification of human gliomas using matrix-based comparative genomic hybridization

scientific article published in October 2005

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

scientific article published in March 2011

Molecular staging of intracranial ependymoma in children and adults

scientific article published in June 2010

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

scientific article published on 25 November 2019

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

scientific article

Molecular subgroups of medulloblastoma: the current consensus

scientific article

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

scientific article published on 09 October 2013

NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING.

scientific article published in July 2014

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib

scientific article published on 18 September 2017

Neoadjuvant therapy with gemcitabine in breast cancer

scientific article

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

scientific article published on 28 July 2016

No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients

scientific article published on 11 March 2016

Nos2 Inactivation Promotes the Development of Medulloblastoma in Ptch1+/− Mice by Deregulation of Gap43–Dependent Granule Cell Precursor Migration ⬇️

scientific article published on March 15, 2012

Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.

scientific article

Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome

scientific article published in July 2009

Nuclear RNAs confined to a reticular compartment between chromosome territories

scientific article

Nuclear body movement is determined by chromatin accessibility and dynamics

scientific article

Obligation for cell line authentication: appeal for concerted action

scientific article published on 01 January 2010

Off-target effects of siRNA specific for GFP

scientific article

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

scientific article published on 20 March 2011

Optimization of high-density cDNA-microarray protocols by 'design of experiments'.

scientific article

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

scientific article (publication date: April 2009)

Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth

scientific article

P42: High resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histological and genetic subgroups of invasive breast cancer

P45: Comprehensive genomic analysis of desmoplastic medulloblastomas reveals novel amplified genes and supports a monoclonal origin of the different histologic components

article

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

scientific article

PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia

scientific article published on 23 March 2015

PM-09REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B

scientific article published in November 2014

PNR-21FOUR NEW BRAIN TUMOR ENTITIES EMERGE FROM MOLECULAR CLASSIFICATION OF CNS PNETs

scientific article published on 30 May 2016

PROGNOSTIC SIGNIFICANCE OF CLINICAL, HISTOPATHOLOGICAL, AND MOLECULAR CHARACTERISTICS OF MEDULLOBLASTOMAS IN THE PROSPECTIVE HIT2000 MULTICENTER CLINICAL TRIAL COHORT

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

scientific article published on February 2014

Patient-based cross-platform comparison of oligonucleotide microarray expression profiles.

scientific article

Pilocytic Astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response

scientific article published on 13 February 2020

Podoplanin is a novel fos target gene in skin carcinogenesis

scientific article published in September 2008

Preeclampsia: increased expression of soluble ADAM 12.

scientific article published on 25 October 2005

Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells

scientific article

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

scientific article

Protein phosphatase 1, regulatory subunit 15B is a survival factor for ERα-positive breast cancer

scientific article published on 27 December 2012

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 17 March 2021

Quantitative gene expression deregulation in mantle-cell lymphoma: correlation with clinical and biologic factors

scientific article published on 11 June 2007

Quantitative proteomics identify novel miR-155 target proteins.

scientific article

QuickLIMS: facilitating the data management for DNA-microarray fabrication

scientific article

Recollections of a scientific journey published in human genetics: from chromosome territories to interphase cytogenetics and comparative genome hybridization

scientific article

Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC).

scientific article published on 27 June 2006

Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma.

scientific article

Recurrent coamplification of cytoskeleton-associated genesEMS1 andSHANK2 withCCND1 in oral squamous cell carcinoma

article

Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma

scientific article published in January 2010

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

scientific article

Reply to J.C. Lindsey et al

Report: workshop on mediastinal grey zone lymphoma

scientific article published in July 2005

Report: workshop on mediastinal grey zone lymphoma

article by Sibrand Poppema et al published 6 June 2005 in European Journal of Haematology

Reprogramming of the ERRα and ERα target gene landscape triggers tamoxifen resistance in breast cancer

scientific article

Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib

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Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial

scientific article published on 16 May 2018

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

scientific article published on 14 May 2013

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

scientific article

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.

scientific article published in July 2014

Severe mental retardation with breathing abnormalities (Pitt-Hopkins syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor TCF4.

scientific article

Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in vivo

scientific article published on 26 July 2010

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

scientific article published on 11 June 2015

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

scientific article

Spatial heterogeneity in medulloblastoma

scientific article published on 10 April 2017

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

scientific article

Stem cell marker CD133 affects clinical outcome in glioma patients

scientific article published in January 2008

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma

scientific article published in March 2009

Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas

scientific article

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus

scientific article published on 09 September 2016

TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES.

scientific article published on 30 May 2016

TNF receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin

scientific article published on 11 January 2018

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome ⬇️

scientific article published on December 20, 2011

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

scientific article

Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism

scientific article published on 14 June 2016

Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival

scientific article published on 15 May 2014

Telomere dysfunction and chromothripsis

scientific article published on 9 February 2016

The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma

scientific article published in March 2008

The landscape of chromothripsis across adult cancer types

scientific article published on 08 May 2020

The landscape of genomic alterations across childhood cancers

scientific article published on 28 February 2018

The landscape of viral associations in human cancers

scientific article published on 05 February 2020

The molecular landscape of ETMR at diagnosis and relapse

scientific article published on 04 December 2019

The need for a worldwide consensus for cell line authentication: Experience implementing a mandatory requirement at the International Journal of Cancer

scientific article

The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation

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The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone

scientific article

The role of epigenetics in carcinogenesis

scientific article published on 01 July 2008

The whole-genome landscape of medulloblastoma subtypes

scientific article published in July 2017

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

scientific article published on 20 December 2017

Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma

scientific article published on 01 March 2003

Topology of genes and nontranscribed sequences in human interphase nuclei

article

Toward understanding and exploiting tumor heterogeneity

scientific article

Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes

scientific article

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

scientific article published in July 2017

Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma

scientific article

V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia.

scientific article published in August 2002

VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: correlation with genomic aberrations, clinical characteristics, and outcome.

scientific article

Whole exome sequencing reveals that the majority of schwannomatosis cases remain unexplained after excluding SMARCB1 and LZTR1 germline variants

article published in 2014

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

scientific article published on 02 September 2019

hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells

scientific article

miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells

scientific article

penalizedSVM: a R-package for feature selection SVM classification

scientific article

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