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List of works by Peter Howley

26 Eukaryotic cloning vectors derived from bovine papillomavirus DNA

scientific article published on January 1, 1983

A Stable Bovine Papillomavirus Hybrid Plasmid That Expresses a Dominant Selective Trait ⬇️

scientific article published on November 1, 1983

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

scientific article

A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes

scientific article

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator.

scientific article

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product ⬇️

scientific article published on May 15, 1992

Angelman syndrome-associated point mutations in the Zn2+-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome

scientific article published on 26 September 2018

Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600

scientific article (published 2005-08-09)

Beta genus papillomaviruses and skin cancer.

scientific article published on 24 February 2015

Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein.

scientific article

Bovine Papilloma Virus Deoxyribonucleic Acid: a Novel Eucaryotic Cloning Vector ⬇️

scientific article published on June 1, 1981

Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding

scientific journal article

Brd4-independent transcriptional repression function of the papillomavirus e2 proteins

scientific article

CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation

scientific article

Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9.

scientific article published on December 2009

Characterization of supercoiled oligomeric SV40 DNA molecules in productively infected cells ⬇️

scientific article published on May 1, 1976

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

scientific article published on February 1993

Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins

scientific article

Comprehensive Analysis of Host Cellular Interactions with Human Papillomavirus E6 Proteins Identifies New E6 Binding Partners and Reflects Viral Diversity ⬇️

scientific article published on September 26, 2012

Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro ⬇️

scientific article published on August 15, 1992

Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling.

scientific article

DNA sequence of human papovavirus BK ⬇️

scientific article published on March 13, 1980

DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a

scientific article

Differentiation of human epidermal cells transformed by SV40.

scientific article

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity

scientific article published on April 1992

E6-AP directs the HPV E6-dependent inactivation of p53 and is representative of a family of structurally and functionally related proteins.

scientific article published on January 1994

E6AP and calmodulin reciprocally regulate estrogen receptor stability.

scientific article published on 28 November 2005

Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses ⬇️

scientific article published on May 15, 1992

Endocrine studies in cystinosis: compensated primary hypothyroidism

scientific article published on August 1, 1977

Evaluation of normal and neoplastic human tissue for BK virus ⬇️

scientific article published on October 15, 1978

Functional interaction between the early viral proteins of simian virus 40 and adenovirus.

scientific article published in March 1981

Genome structures of reiteration mutants of simian virus 40 ⬇️

scientific article published on March 1, 1977

Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression

scientific article

Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes.

scientific article

Growth Potential of Sheep and Sea Mammal Cells Transformed by SV40 Early Region DNA ⬇️

scientific article published on September 1, 1980

Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins

scientific article published on 01 September 2000

High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.

scientific article published on 20 September 2016

Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40 ⬇️

scientific article published on July 1, 1975

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

scientific article

Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B

scientific article

Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination.

scientific article

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

scientific article

In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA.

scientific article published in September 1980

Inducible expression of the human interferon beta 1 gene linked to a bovine papilloma virus DNA vector and maintained extrachromosomally in mouse cells.

scientific article published on February 1983

Inhibition of E2 binding to Brd4 enhances viral genome loss and phenotypic reversion of bovine papillomavirus-transformed cells.

scientific article

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

scientific article published on April 1996

Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

scientific article

Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells

scientific article

Isolation of Simian Virus 40 from Rhesus Monkeys (Macaca mulatta) with Spontaneous Progressive Multifocal Leukoencephalopathy ⬇️

scientific article published on October 1, 1977

Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes

scientific article

Lack of SV40 DNA in Tumors from Scientists Working with SV40 Virus ⬇️

scientific article published on February 14, 1991

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

scientific article

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences

scientific article

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

scientific article published in May 1999

NCoR1 mediates papillomavirus E8;E2C transcriptional repression

scientific article

NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism

scientific article

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes

scientific article published on 6 February 2018

Novel method for identifying sequence-specific DNA-binding proteins.

scientific article published on September 1985

On human papillomaviruses.

scientific article

Oncogenicity of a nude mouse cell line transformed by a human papovavirus

scientific article published on April 1, 1977

Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes.

scientific article

Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens

scientific article published on 24 December 2014

Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity

scientific article

Polynucleotide sequences common to the genomes of simian virus 40 and the human papovaviruses JC and BK ⬇️

scientific article published on August 1, 1976

Presence of human papilloma viral antigens in juvenile multiple laryngeal papilloma.

scientific article

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

scientific article

Proteomic approaches to the study of papillomavirus-host interactions.

scientific article

Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination

scientific article

Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells.

scientific article

Requirement of E7 oncoprotein for viability of HeLa cells.

scientific article

SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter

scientific article published on 16 September 2014

Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a

scientific article

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

scientific article

Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.

scientific article

The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3 ⬇️

scientific article published on May 9, 2011

The ER-lumenal domain of the HHV-7 immunoevasin U21 directs class I MHC molecules to lysosomes.

scientific article published on December 2003

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

scientific article

The SMC5/6 complex interacts with the papillomavirus E2 protein and influences maintenance of viral episomal DNA

scholarly article by Peris Bentley et al published 30 May 2018 in Journal of Virology

The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.

scientific article

The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase

scientific article published on 01 December 1997

The colinear alignment of the genomes of papovaviruses JC, BK, and SV40 ⬇️

scientific article published on July 30, 1979

The genetics of bovine papillomavirus type 1.

scientific article

The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling.

scientific article published on 20 December 2017

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

scientific article

Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells

scientific article

Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.

scientific article

Type 1 human T-cell leukemia virus small envelope protein expressed in mouse cells by using a bovine papilloma virus-derived shuttle vector.

scientific article published on November 1985

Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.

scientific article

Ubiquitin recognition by the DNA repair protein hHR23a.

scientific article published in November 2003

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

scientific article published on 01 November 1998

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

scientific journal article

Virus-specific transcription in bovine papillomavirus-transformed mouse cells ⬇️

scientific article published on May 1, 1982

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

scientific article

p35, the Neuronal-specific Activator of Cyclin-dependent Kinase 5 (Cdk5) Is Degraded by the Ubiquitin-Proteasome Pathway ⬇️

scientific article published on September 11, 1998

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