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List of works by Michael Hallek

1568. Implementation of a Standard Diet Regimen for Neutropenic High-Risk Cancer Patients: Effects on Incidence of Infections, Foodborne Diseases, and Outcome

A Novel Recombinant Anti-CD22 Immunokinase Delivers Proapoptotic Activity of Death-Associated Protein Kinase (DAPK) and Mediates Cytotoxicity in Neoplastic B Cells

scientific article published on 29 January 2016

A cost calculation model for specialist palliative care for patients with non-small cell lung cancer in a tertiary centre

scientific article published on 2 October 2007

A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo

scientific article published on 6 October 2005

A polyvalent cellular vaccine induces T-cell responses against specific self-antigens overexpressed in chronic lymphocytic B-cell leukemia.

scientific article

A prospective study of serum soluble CD30 in allogeneic hematopoietic stem cell transplantation

scientific article published on 08 July 2010

A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplant

scientific article published on 13 January 2011

A rare case of t(11;22) in a mantle cell lymphoma like B-cell neoplasia resulting in a fusion of IGL and CCND1: case report

scientific article published on April 2011

A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation

scientific article published on 2 February 2009

AAV-based gene transfer

scientific article published on August 1, 2003

AKT-pathway inhibition in chronic lymphocytic leukemia reveals response relationships defined by TCL1.

scientific article published in January 2014

Activity of cetuximab as single agent in a patient with relapsed multiple myeloma.

scientific article

Addition of high-dose cytarabine to immunochemotherapy before autologous stem-cell transplantation in patients aged 65 years or younger with mantle cell lymphoma (MCL Younger): a randomised, open-label, phase 3 trial of the European Mantle Cell Lymp

scientific article published on 13 June 2016

Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors

scientific article

Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency

scientific article published on November 2005

Advances in first-line treatment of chronic lymphocytic leukemia: current recommendations on management and first-line treatment by the German CLL Study Group (GCLLSG).

scientific article published on 02 September 2015

Alemtuzumab (Lemtrada, MabCampath)1

Alemtuzumab consolidation in chronic lymphocytic leukaemia: a phase I/II multicentre trial

scientific article published on 9 November 2016

Alemtuzumab, the first monoclonal antibody (MAb) directed against CD52

scientific article published on 01 January 2002

Alemtuzumab: what is the secret to safe therapy?

scientific article published on May 2011

Allogeneic Hematopoietic Cell Transplantation in Patients Aged 50Years or Older with Severe Aplastic Anemia

scholarly article by Carmel Rice et al published March 2019 in Biology of Blood and Marrow Transplantation

Allogeneic hematopoietic cell transplantation for high-risk CLL: 10-year follow-up of the GCLLSG CLL3X trial

scientific article published on 17 July 2017

Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial

scientific article published in July 2010

An open-label pilot study of the efficacy and safety of anakinra in patients with psoriatic arthritis refractory to or intolerant of methotrexate (MTX).

scientific article published on 9 June 2010

Analysis of ITGB2 rare germ line variants in chronic lymphocytic leukemia

scientific article published on 19 October 2017

Analysis of site-specific transgene integration following cotransduction with recombinant adeno-associated virus and a rep encodingplasmid

scientific article published in February 2003

Anti-epidermal growth factor receptor antibody cetuximab in refractory or relapsed multiple myeloma: a phase II prospective clinical trial

scientific article published on 29 July 2013

Anti-thymocyte globulins for post-transplant graft-versus-host disease prophylaxis-A systematic review and meta-analysis

scientific article published on 02 April 2013

Antigen-presenting human B cells are expanded in inflammatory conditions

scientific article published on 17 August 2016

Artificial evolution with adeno-associated viral libraries

scientific article

Atrial fibrillation in patients with chronic lymphocytic leukemia (CLL).

scientific article published on 25 November 2016

Autologous hematopoietic stem cell transplantation in chronic lymphocytic leukemia: results of European intergroup randomized trial comparing autografting versus observation

scientific article published on 24 November 2010

B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides

scientific article published on 27 August 2012

BRAF inhibition in hairy cell leukemia with low-dose vemurafenib

scientific article

Bendamustine and its role in the treatment of unfit patients with chronic lymphocytic leukaemia: a perspective review

scientific article published on 30 March 2017

Bendamustine and rituximab in combination with lenalidomide in patients with chronic lymphocytic leukemia

scientific article published on 8 December 2015

Bendamustine combined with rituximab in patients with relapsed and/or refractory chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group

scientific article

Bendamustine in combination with rituximab for previously untreated patients with chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group

scientific article

Bendamustine plus mitoxantrone for relapsed/refractory chronic lymphocytic leukaemia (CLL): results of a multicentre phase II study of the German CLL Study Group (GCLLSG).

scientific article

Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells

scientific article

Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission

scientific article

CD23 is recognized as tumor-associated antigen (TAA) in B-CLL by CD8+ autologous T lymphocytes

scientific article published in June 2007

CD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro

scientific article published on 20 April 2016

CD30-targeted therapy with brentuximab vedotin and DLI in a patient with T-cell posttransplantation lymphoma: induction of clinical remission and cellular immunity

scientific article published in August 2013

CD40L stimulation enhances the ability of conventional metaphase cytogenetics to detect chromosome aberrations in B-cell chronic lymphocytic leukaemia cells

scientific article

CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia.

scientific article published in April 2013

CLL2-BXX Phase II trials: sequential, targeted treatment for eradication of minimal residual disease in chronic lymphocytic leukemia

scientific article published on 21 February 2018

Characterization of tumor-associated B-cell subsets in patients with colorectal cancer

scientific article

Chemoimmunotherapy--towards real progress in the treatment of chronic lymphocytic leukemia

scientific article published on 01 July 2005

Chemotherapeutic agents enhance AAV2-mediated gene transfer into breast cancer cells promoting CD40 ligand-based immunotherapy

scientific article published on 23 June 2006

Chemotherapy combination treatment regimens with fludarabine in chronic lymphocytic leukemia

scientific article published on January 2004

Chemotherapy plus Rituximab versus chemotherapy alone for B-cell non-Hodgkin's lymphoma

scientific article

Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia

scientific article published on 22 September 2005

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

scientific article published on 23 May 2017

Chronic lymphocytic leukemia

scientific article published on 01 October 2010

Chronic lymphocytic leukemia (CLL): first-line treatment

scientific article

Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment ⬇️

scientific article published on September 1, 2013

Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment

scientific article

Chronic lymphocytic leukemia: 2017 update on diagnosis, risk stratification, and treatment

scientific article

Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies.

scientific article

Clinical safety and pharmacological profile of the HLA-DR antibody 1D09C3 in patients with B cell chronic lymphocytic leukemia and lymphoma: results from a phase I study

scientific article published on 23 October 2012

Clinical trials in Germany: the time to reduce bureaucracy has come!

scientific article published on 31 March 2015

Combination of Targeted Drugs to Control Chronic Lymphocytic Leukemia: Harnessing the Power of New Monoclonal Antibodies in Combination With Ibrutinib

scientific article published on January 2016

Combinatorial engineering of a gene therapy vector: directed evolution of adeno-associated virus

scientific article

Combined paracrine and endocrine AAV9 mediated expression of hepatocyte growth factor for the treatment of renal fibrosis

scientific article

Comparison of the effects of two kinase inhibitors, sorafenib and dasatinib, on chronic lymphocytic leukemia cells

scientific article

Comparison of the in vitro effects of the anti-CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells

scientific article published on 13 December 2010

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy

scientific article

Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing

scientific article published in 2015

Comprehensive genomic profiles of small cell lung cancer

scientific article published on 13 July 2015

Confirmation of the mantle-cell lymphoma International Prognostic Index in randomized trials of the European Mantle-Cell Lymphoma Network

scientific article published on 31 March 2014

Consolidation with alemtuzumab improves progression-free survival in patients with chronic lymphocytic leukaemia (CLL) in first remission: long-term follow-up of a randomized phase III trial of the German CLL Study Group (GCLLSG).

scientific article published on 30 October 2008

Control measures following a case of imported Lassa fever from Togo, North Rhine Westphalia, Germany, 2016.

scientific article published on September 2017

Conventional cytogenetics in chronic lymphocytic leukemia (CLL)

scientific article published on 11 November 2010

Copanlisib for treatment of B-cell malignancies: the development of a PI3K inhibitor with considerable differences to idelalisib

article

Correction: Patients with Acute Myeloid Leukemia Admitted to Intensive Care Units: Outcome Analysis and Risk Prediction

scientific article published on 2 January 2018

Cost-effectiveness of rituximab in addition to fludarabine and cyclophosphamide (R-FC) for the first-line treatment of chronic lymphocytic leukemia

scientific article published on 20 November 2015

Current and future indications for bendamustine: chronic lymphocytic leukemia, indolent lymphoma, mantle cell lymphoma and diffuse large B-cell lymphomas

scientific article

Current strategies to create tailored and risk-adapted therapies for CLL patients

scientific article

Cytokine release in patients with CLL treated with obinutuzumab and possible relationship with infusion-related reactions

scientific article published on 7 October 2015

Cytomorphologic signs of severe pernicious anemia obscured in a patient with heterozygous hemoglobin Stanleyville II

scientific article published on 03 August 2007

Cytotoxicity of the CD37 antibody BI 836826 against chronic lymphocytic leukaemia cells in combination with chemotherapeutic agents or PI3K inhibitors.

scientific article

Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor

scientific article

Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy

scientific article

Dendritic cell-based immunogens for B-cell chronic lymphocytic leukemia

scientific article published on 03 March 2006

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial.

scientific article published on 30 July 2009

Development of a comprehensive prognostic index for patients with chronic lymphocytic leukemia

scientific article

Development of efficient viral vectors selective for vascular smooth muscle cells

scientific article published in February 2004

Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene transfer

scientific article published on 11 September 2012

Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade

scientific article published on 5 October 2008

Dose-reduced fludarabine, cyclophosphamide and rituximab (FCR) in older patients with chronic lymphocytic leukemia: does one size fit all?

scientific article published in May 2016

Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases

scientific article published on 5 September 2002

Due to low infection rates no routine anti-infective prophylaxis is required in younger patients with chronic lymphocytic leukaemia during fludarabine-based first line therapy

scientific article published on 03 November 2006

Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial

scientific article published on 05 April 2012

Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography

scientific article published on 21 March 2011

Economic evaluation of chronic lymphocytic leukemia from a hospital management perspective

scientific article

Effects of Kyusho Jitsu on Physical Activity-levels and Quality of Life in Breast Cancer Patients.

scientific article published in July 2018

Efficacy and safety of moxifloxacin as antibacterial prophylaxis for patients receiving autologous haematopoietic stem cell transplantation: a randomised trial

scientific article published on 12 December 2011

Efficacy of antineoplastic treatment is associated with the use of antibiotics that modulate intestinal microbiota

scientific article published on 22 April 2016

Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells

scientific article published on 24 April 2015

Efficient gene transfer of CD40 ligand into ovarian carcinoma cells with a recombinant adeno-associated virus vector.

scientific article

Efficient gene transfer of CD40 ligand into primary B-CLL cells using recombinant adeno-associated virus (rAAV) vectors.

scientific article published on September 2002

Efficient gene transfer to periodontal ligament cells and human gingival fibroblasts by adeno-associated virus vectors

scientific article published on 11 April 2009

Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing

scientific article published on May 2014

Emerging therapies for refractory chronic lymphocytic leukemia

scientific article published on 27 June 2014

Engineered T cells for the adoptive therapy of B-cell chronic lymphocytic leukaemia

scientific article published on 8 August 2011

Engineering adeno-associated virus serotype 2-based targeting vectors using a new insertion site-position 453-and single point mutations

scientific article published on 01 December 2009

Enhancement of gene transfer with recombinant adeno-associated virus (rAAV) vectors into primary B-cell chronic lymphocytic leukemia cells by CpG-oligodeoxynucleotides

scientific article published in December 2003

Eradication of minimal residual disease in chronic lymphocytic leukemia

scientific article published on January 2008

Erufosine, a novel alkylphosphocholine, induces apoptosis in CLL through a caspase-dependent pathway

scientific article

Establishing a chemical genetic link between Bruton tyrosine kinase activity in malignant B cells and cell functions involved in the micro-environmental dialogue

scientific article published in June 2017

Evaluation of geriatric assessment in patients with chronic lymphocytic leukemia: Results of the CLL9 trial of the German CLL study group

scientific article published on 17 September 2015

Extracellular vesicles released from chronic lymphocytic leukemia cells exhibit a disease relevant mRNA signature and transfer mRNA to bystander cells

scientific article published on 17 November 2016

Extramedullary manifestations of chronic lymphocytic leukaemia are not unusual

scientific article published in December 2013

FCA: forget chemoimmunotherapy with alemtuzumab?

scientific article published on 01 May 2012

FCR front-line therapy and quality of life in patients with chronic lymphocytic leukemia

scientific article published on 29 June 2016

FLAMSA reduced-intensity conditioning is equally effective in AML patients with primary induction failure as well as in first or second complete remission

scientific article

Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report

Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes

scientific article

FimH-based display of functional eukaryotic proteins on bacteria surfaces.

scientific article

Final results of EFC6663: a multicenter, international, phase 2 study of alvocidib for patients with fludarabine-refractory chronic lymphocytic leukemia

scientific article

Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia

scientific article

First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, open-label, randomised, phase 3, non-inferiority tri

scientific article published on 20 May 2016

First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia

scientific article published on 15 July 2009

Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia

scientific article

Fludarabine in chronic lymphocytic leukaemia

scientific article published on August 2006

Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: results of a phase II trial

scientific article

Fludarabine plus alemtuzumab versus fludarabine alone in patients with previously treated chronic lymphocytic leukaemia: a randomised phase 3 trial

scientific article

Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia

scientific article

Focus on academic multicenter trials: impact of the German drug law on hematological/oncological therapy optimization trials

scientific article published on January 2013

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

scientific article

Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

scientific article

Future prospects for alemtuzumab (MabCampath).

scientific article

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial

scientific article published on 20 March 2014

Gene transfer into human cord blood-derived CD34(+) cells by adeno-associated viral vectors

scientific article published on 4 May 2010

Gene transfer preferentially selects MHC class I positive tumour cells and enhances tumour immunogenicity

scientific article

Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking

scientific article

Guidelines for diagnosis, indications for treatment, response assessment and supportive management of chronic lymphocytic leukemia

scientific article published on 14 March 2018

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

scientific article

Health-related quality of life in younger patients with chronic lymphocytic leukemia treated with fludarabine plus cyclophosphamide or fludarabine alone for first-line therapy: a study by the German CLL Study Group

scientific article published on 26 March 2007

Hematological cancer in 2011: New therapeutic targets and treatment strategies

scientific article published on 10 January 2012

Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism

scientific article published in July 2006

High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia

scientific article published on 21 September 2009

High level of transgene expression in primary chronic lymphocytic leukemia cells using helper-virus-free recombinant Epstein-Barr virus vectors

scientific article published in February 2003

Human Ly9 (CD229) as novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (B-CLL) recognized by autologous CD8+ T cells

scientific article published in July 2006

Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells

scientific article

Ibrutinib combined with bendamustine and rituximab compared with placebo, bendamustine, and rituximab for previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (HELIOS): a randomised, double-blind, phase 3 study

scientific article

Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study

scientific article published on 13 September 2016

Idelalisib and rituximab in relapsed chronic lymphocytic leukemia

scientific article

Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis

scientific article published on May 2007

Immunological effects in patients with steroid-refractory graft-versus-host disease following treatment with basiliximab, a CD25 monoclonal antibody

scientific article

Impact of rituximab and radiotherapy on outcome of patients with aggressive B-cell lymphoma and skeletal involvement

scientific article published on 23 September 2013

Impact of telomere length on the outcome of allogeneic stem cell transplantation for poor-risk chronic lymphocytic leukaemia: results from the GCLLSG CLL3X trial

scientific article published on 8 July 2016

Implementing WHO recommendations for palliative care into routine lung cancer therapy: a feasibility project

scientific article published on 01 June 2010

In vitro selection of viral vectors with modified tropism: the adeno-associated virus display

scientific article

Incorporating targeted agents into future therapy of chronic lymphocytic leukemia

scientific article

Influence of endurance exercise on the risk of pneumonia and Fever in leukemia and lymphoma patients undergoing high dose chemotherapy. A pilot study

scientific article published on December 2012

Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity

scientific article published on 13 October 2014

Initial therapy of chronic lymphocytic leukemia

scientific article published on 9 February 2016

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

scientific article

Interactions between comorbidity and treatment of chronic lymphocytic leukemia: results of German Chronic Lymphocytic Leukemia Study Group trials

scientific article

Interindividual variability of response to rituximab: from biological origins to individualized therapies

scientific article published on January 2011

Interleukin-6-mediated cell growth in multiple myeloma--a role for Viscum album extracts?

scientific article published on 29 August 2005

Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia

scientific article

Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles

scientific article published on 25 October 2010

Is physical exercise possible in patients with critical cytopenia undergoing intensive chemotherapy for acute leukaemia or aggressive lymphoma?

scientific article

LYN Kinase in the Tumor Microenvironment Is Essential for the Progression of Chronic Lymphocytic Leukemia

scientific article published in October 2016

Lenalidomide maintenance after first-line therapy for high-risk chronic lymphocytic leukaemia (CLLM1): final results from a randomised, double-blind, phase 3 study

scientific article published on 12 September 2017

Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis ⬇️

scientific article published on December 7, 2010

Long-term follow-up of idiopathic thrombotic thrombocytopenic purpura treated with rituximab

scientific article

Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: updated results of the CLL8 trial

scientific article published on 20 October 2015

Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation

scientific article

Low-dose fludarabine with or without darbepoetin alfa in patients with chronic lymphocytic leukemia and comorbidity: primary results of the CLL9 trial of the German CLL Study Group

scientific article published on 21 August 2015

Lyme disease in a patient with chronic lymphocytic leukemia mimics leukemic meningeosis

scientific article published on 16 October 2007

MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes

scientific article published in January 2006

Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin

scientific article

Management of chronic lymphocytic leukemia

scientific article

Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab

scientific article

Minimal Residual Disease Assessment Improves Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia (CLL) Who Achieve Partial Response: Comprehensive Analysis of Two Phase III Studies of the German CLL Study Group

scientific article published on 29 August 2016

Modification and labeling of AAV vector particles

scientific article published in January 2011

Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia

scientific article published on 15 July 2016

Mutations driving CLL and their evolution in progression and relapse

scientific article published on 14 October 2015

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib

scientific article published on 18 September 2017

NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG.

scientific article published on 2 July 2013

Natural ligands and antibody-based fusion proteins: harnessing the immune system against cancer

scientific article

New menus for CLL treatment

scientific article published on 01 November 2009

New treatment approaches in CLL: Challenges and opportunities in the elderly

scientific article

Nitric oxide-donating acetylsalicylic acid induces apoptosis in chronic lymphocytic leukemia cells and shows strong antitumor efficacy in vivo

scientific article published on 19 November 2010

Novel X-linked inhibitor of apoptosis inhibiting compound as sensitizer for TRAIL-mediated apoptosis in chronic lymphocytic leukaemia with poor prognosis

scientific article published on 23 November 2010

OCTET-CY: a phase II study to investigate the efficacy of post-transplant cyclophosphamide as sole graft-versus-host prophylaxis after allogeneic peripheral blood stem cell transplantation

scientific article published on 23 February 2015

Obinutuzumab (GA101) in relapsed/refractory chronic lymphocytic leukemia: final data from the phase 1/2 GAUGUIN study

scientific article

Obinutuzumab in chronic lymphocytic leukemia: design, development and place in therapy

scientific article published on 25 January 2017

Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

On taking a different route: an unlikely case of malaria by nosocomial transmission

scientific article published on 2 June 2017

On the assessment of dasatinib-induced autophagy in CLL ⬇️

scientific article published on October 14, 2010

Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: considerations in the elderly

scientific article published on March 2011

Optimization of rituximab for the treatment of diffuse large B-cell lymphoma (II): extended rituximab exposure time in the SMARTE-R-CHOP-14 trial of the german high-grade non-Hodgkin lymphoma study group

scientific article published on 17 November 2014

Optimization of stealth adeno-associated virus vectors by randomization of immunogenic epitopes

scientific article

Optimizing frontline therapy of CLL based on clinical and biological factors.

scientific article published in December 2017

Outcome of advanced chronic lymphocytic leukemia following different first-line and relapse therapies: a meta-analysis of five prospective trials by the German CLL Study Group (GCLLSG).

scientific article published on 27 August 2015

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease.

scientific article

PTK2 expression and immunochemotherapy outcome in chronic lymphocytic leukemia

scientific article published on 10 June 2014

Past, present and future role of chlorambucil in the treatment of chronic lymphocytic leukemia

scientific article

Patients with Acute Myeloid Leukemia Admitted to Intensive Care Units: Outcome Analysis and Risk Prediction

scientific article

Personalized cancer medicine

scientific article published on 20 January 2012

Perspectives for onkologie

scientific article published on 25 November 2011

Perspectives on the use of new diagnostic tools in the treatment of chronic lymphocytic leukemia

scientific article

Pharmacokinetics of alemtuzumab and the relevance in clinical practice

scientific article published on December 2008

Pharmacokinetics of alemtuzumab in combination with fludarabine in patients with relapsed or refractory B-cell chronic lymphocytic leukemia

scientific article published on 10 November 2008

Pharmacotherapeutic Management of Chronic Lymphocytic Leukaemia in Patients with Comorbidities: New Agents, New Hope

scientific article published on 07 October 2015

Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia

scientific article

Phosphorylation of src Family lck Tyrosine Kinase Following Interleukin-12 Activation of Human Natural Killer Cells

Physiologic evaluation in the elderly prior to treatment with chemotherapy

scientific article published on August 2007

Poor efficacy and tolerability of R-CHOP in relapsed/refractory chronic lymphocytic leukemia and Richter transformation

scientific article

Population pharmacokinetics of escalating doses of caspofungin in a phase II study of patients with invasive aspergillosis

scientific article published on 18 January 2013

Posaconazole concentrations in the central nervous system

scientific article published on 28 September 2008

Post-chemotherapy cognitive impairment in patients with B-cell non-Hodgkin lymphoma: a first comprehensive approach to determine cognitive impairments after treatment with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone or ritux

scientific article

Priorities of German Oncologists. Results of the "choosing wisely" survey of the German Society of Hematology and Medical Oncology (DGHO)

scientific article

Professor Hans-Joachim Schmoll 10 Years Editor-in-Chief of Onkologie ⬇️

scientific article published on November 21, 2012

Prognostic Value of Ki-67 Index, Cytology, and Growth Pattern in Mantle-Cell Lymphoma: Results From Randomized Trials of the European Mantle Cell Lymphoma Network

scientific article

Prognostic factors in chronic lymphocytic leukemia-what do we need to know?

scientific article published on 19 October 2010

Prognostication of chronic lymphocytic leukemia in the era of new agents

scientific article

Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia

scientific article

Progress due to networking structures. Challenges for the Competence Network Malignant Lymphomas in the Era of Precision Medicine

scientific article published in April 2016

Progress in the use of adeno-associated viral vectors for gene therapy

scientific article published in January 2004

Protrusion-guided extracellular vesicles mediate CD30 trans-signalling in the microenvironment of Hodgkin's lymphoma

scientific article

RIG-I activation induces the release of extracellular vesicles with antitumor activity

scientific article published on 19 August 2016

Randomized phase 2 study of otlertuzumab and bendamustine versus bendamustine in patients with relapsed chronic lymphocytic leukaemia

scientific article published on 15 December 2016

Recent developments in adeno-associated virus vector technology

scientific article

Recommending early integration of palliative care - does it work?

scientific article published on 19 February 2011

Rediscovering alemtuzumab: current and emerging therapeutic roles

scientific article published on 08 January 2009

Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

scientific article published on 24 May 2005

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial

scientific article

Reduced-intensity conditioning in allogeneic stem cell transplantation for hematological malignancies: a historical perspective

scientific article

Regulatory B10 cells display an altered homoeostasis in acute graft-versus-host disease

scientific article

Report on the 1st international workshop of the german competence network malignant lymphomas

scientific article published on 25 April 2007

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

scientific article published on 18 April 2004

Revision of the guidelines for diagnosis and therapy of chronic lymphocytic leukemia (CLL).

scientific article published in September 2007

Risk categories and refractory CLL in the era of chemoimmunotherapy

scientific article published on 06 March 2012

Rituximab and alemtuzumab induce a nonclassic, caspase-independent apoptotic pathway in B-lymphoid cell lines and in chronic lymphocytic leukemia cells

scientific article published on 7 August 2004

Rituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia

scientific article

Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells

scientific article published on 25 October 2007

Safety and efficacy of different lenalidomide starting doses in patients with relapsed or refractory chronic lymphocytic leukemia: results of an international multicenter double-blinded randomized phase II trial

scientific article

Second-line therapies of patients initially treated with fludarabine and cyclophosphamide or fludarabine, cyclophosphamide and rituximab for chronic lymphocytic leukemia within the CLL8 protocol of the German CLL Study Group

scientific article published on 12 June 2013

Sensitizing protective tumor microenvironments to antibody-mediated therapy

scientific article published on January 2014

Sequential Intensified Conditioning Regimen Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Intermediate- or High-Risk Acute Myeloid Leukemia in Complete Remission: A Study from the Acute Leukemia Working Party of the Europ

scientific article published on 2 November 2016

Signaling the end of chronic lymphocytic leukemia: new frontline treatment strategies

scientific article

Similar outcome after allogeneic stem cell transplantation with a modified FLAMSA conditioning protocol substituting 4 Gy TBI with treosulfan in an elderly population with high-risk AML.

scientific article published on December 2016

Single virus tracing: visualization of the infection pathway of a virus into a living cell

scientific article published in March 2002

Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.

scientific article published on 20 November 2008

Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

scientific article

Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

scientific article published on 18 March 2013

Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence

scientific article published in Scientific Reports

Specifying WHO recommendation: moving toward disease-specific guidelines

scientific article published in October 2010

Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner

scientific article published on August 2007

Standardizing integration of palliative care into comprehensive cancer therapy--a disease specific approach

scientific article published on 24 March 2011

State of the art treatment of chronic lymphocytic leukaemia

scientific article

State-of-the-Art Treatment and Novel Agents in Chronic Lymphocytic Leukemia

scientific article

State-of-the-art treatment of chronic lymphocytic leukemia

scientific article published on January 2009

Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group

scientific article

Successful use of rituximab in a patient with Churg-Strauss syndrome and refractory central nervous system involvement

scientific article published on 09 September 2009

TP53 mutation and survival in chronic lymphocytic leukemia

scientific article

TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial

scientific article published on 22 February 2013

Targeted Therapy of CLL.

scientific article published on 15 November 2016

Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors

scientific article

Targeting Tumor-Infiltrating B Cells in Cutaneous T-Cell Lymphoma

scientific article published on 27 October 2014

Targeting the disturbed redox equilibrium in chronic lymphocytic leukemia by novel reactive oxygen species-catalytic 'sensor/effector' compounds

scientific article published on 29 March 2011

Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome

scientific article published on 24 October 2017

The Antineoplastic Effect of Nitric Oxide-Donating Acetylsalicylic Acid (NO-ASA) in Chronic Lymphocytic Leukemia (CLL) Cells is Highly Dependent on its Positional Isomerism

scientific article published on October 2011

The CLL12 trial protocol: a placebo-controlled double-blind Phase III study of ibrutinib in the treatment of early-stage chronic lymphocytic leukemia patients with risk of early disease progression

scientific article

The European LeukemiaNet: achievements and perspectives

scientific article

The HELIOS trial protocol: a phase III study of ibrutinib in combination with bendamustine and rituximab in relapsed/refractory chronic lymphocytic leukemia

scientific article published on January 2015

The Treatment of Chronic Lymphatic Leukemia

The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity

scientific article

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma

scientific article published on 29 November 2013

The effects of Bcr-Abl on C/EBP transcription-factor regulation and neutrophilic differentiation are reversed by the Abl kinase inhibitor imatinib mesylate

scientific article published on 12 September 2002

The erythropoietin receptor in normal and cancer tissues

scientific article

The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years-a report from the EBMT acute leukemia working party

scientific article published on 03 August 2016

The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes

scientific article published on 12 June 2008

The preventive effect of sensorimotor- and vibration exercises on the onset of Oxaliplatin- or vinca-alkaloid induced peripheral neuropathies - STOP.

scientific article published on 10 January 2018

The role of minimal residual disease measurements in the therapy for CLL: is it ready for prime time?

scientific article published on April 2013

The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

scientific article published on 22 June 2010

Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors

scientific article

Therapy of chronic lymphocytic leukaemia

scientific article published on March 2010

Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors

scientific article published in January 2012

Transduction of CLL cells by CD40 ligand enhances an antigen-specific immune recognition by autologous T cells

scientific article

Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors

scientific article published in November 2003

Treatment cost development of patients undergoing remission induction chemotherapy: a pharmacoeconomic analysis before and after introduction of posaconazole prophylaxis

scientific article

Treatment of elderly patients with chronic lymphocytic leukemia

scientific article published on February 2009

Treatment of severe chronic ocular graft-versus-host disease using 100% autologous serum eye drops from a sealed manufacturing system: a retrospective cohort study

scientific article

Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy

scientific article

Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia

scientific article published on 28 July 2017

Ultrasound-guided core needle biopsies for workup of lymphadenopathy and lymphoma

scientific article published on 2 February 2016

Unusual sites of malignancies: CASE 2. Central neurogenic hyperventilation as a complication of Richter's syndrome

scientific article published in March 2005

Use of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) as a diagnostic tool in chronic lymphocytic leukemia (CLL).

scientific article published on 30 April 2011

Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy.

scientific article published on 4 August 2017

Vaccination against B-cell chronic lymphocytic leukemia with trioma cells: preclinical evaluation

scientific article published on September 2003

Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses

scientific article published on 4 January 2006

Venetoclax and obinutuzumab in chronic lymphocytic leukemia

scientific article published on 21 March 2017

Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial

scientific article published in May 2018

Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study

scientific article

Venetoclax plus rituximab or obinutuzumab after allogeneic hematopoietic stem cell transplantation in chronic lymphocytic leukemia

scholarly article by Othman Al-Sawaf et al published May 2019 in Haematologica

Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients

scientific article published on May 2011

Which drugs in Hemato-Oncology are Unnecessary or Inappropriate for Use in the Elderly?

scientific article published on 22 February 2018

Yttrium-90 ibritumomab tiuxetan-induced complete remission in a patient with classical lymphocyte-rich Hodgkin's Lymphoma

scientific article published on 22 January 2008

[What effects has the presence of prolymphocytes on prognosis and therapy of CLL? ]

scientific article published on 01 March 2002

mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice

scientific article published on 16 January 2013

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia

scientific article

miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL.

scientific article published on 10 February 2015

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