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List of works by Peter Carmeliet

"Antimyeloangiogenic" therapy for cancer by inhibiting PlGF.

scientific article published on 26 May 2009

3D systems delivering VEGF to promote angiogenesis for tissue engineering

scientific article published on 3 December 2010

A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity

scientific article published on August 2017

A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span

scientific article published on 30 June 2006

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

scholarly article

A critical role of placental growth factor in the induction of inflammation and edema formation

scientific article published on 05 September 2002

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

scientific article

A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice

scientific article published on 7 July 2017

A key role for transketolase-like 1 in tumor metabolic reprogramming

scientific article published on 06 July 2016

A lifeline for suffocating tissues

scientific article published in Nature

A mouse model for Zellweger syndrome

scientific journal article

A new mouse model to study acquired lymphedema

scientific article published on 18 July 2006

A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia

scientific article

A surrogate marker to monitor angiogenesis at last

scientific article

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

scientific article

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

scientific article published in Nature

Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice

scientific article

Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice

scientific journal article

Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction

scientific article published on 22 December 2008

Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy

scientific article published on 05 October 2009

Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury

scientific article published on 8 February 2010

Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy

scientific article published on 23 May 2011

Abstract 1353: Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6

Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis

scientific article

Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A

article

Adenovirus-mediated transfer of tissue-type plasminogen activator augments thrombolysis in tissue-type plasminogen activator-deficient and plasminogen activator inhibitor-1-overexpressing mice ⬇️

scientific article published on August 15, 1997

Adequate hypoxia inducible factor 1α signaling is indispensable for bone regeneration

scientific article published on 4 April 2016

Adult Pgf-/- mice behaviour and neuroanatomy are altered by neonatal treatment with recombinant placental growth factor

scientific article published on 26 June 2019

Age-dependent neonatal intracerebral hemorrhage in plasminogen activator inhibitor 1 knockout mice

scientific article published on 01 May 2014

Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms

scientific article published on 24 April 2007

Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice

scientific article published on 27 February 2003

Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism

scientific article published on 22 February 2013

Allosteric targeting of receptor tyrosine kinases.

scientific article published in November 2014

Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes

scientific article published on 2 November 2006

Alzheimer's disease: A breach in the blood-brain barrier

scientific article published on 23 May 2012

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines

scientific article published on 13 March 2020

Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system

scientific article

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 March 2020

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 January 2020

An SDF-1 trap for myeloid cells stimulates angiogenesis

scientific article

Analysis of Endothelial Fatty Acid Metabolism Using Tracer Metabolomics

scientific article published on 01 January 2019

Angiogenesis Revisited: An Overlooked Role of Endothelial Cell Metabolism in Vessel Sprouting

scientific article published on 06 August 2015

Angiogenesis and lymphangiogenesis: highlights of the past year

scientific article published in July 2004

Angiogenesis in health and disease

scientific article (publication date: June 2003)

Angiogenesis in life, disease and medicine

scientific article (publication date: 15 December 2005)

Angiogenesis revisited - role and therapeutic potential of targeting endothelial metabolism

scientific article published on September 2014

Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism

scientific article published in December 2017

Angiogenesis: A Target in Solid Tumors, Also in Leukemia? ⬇️

scientific article published on January 1, 2011

Another angiogenic gene linked to amyotrophic lateral sclerosis

scientific article published on 14 July 2006

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

scientific article

Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation

scientific article published on 3 August 2010

Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

scientific article published on 31 May 2011

Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.

scientific article

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

scientific article

Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity

scholarly article

Author Correction: COVID-19: the vasculature unleashed

scientific article published on 04 June 2020

Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

scientific article published on 10 December 2020

Author Response: Possibility of Cytoplasmic Transportation Between Donor-Host Cell Following Photoreceptor Transplantation

scientific article published in October 2016

Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3

scientific article

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia

scientific article published on 17 November 2016

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

scientific article published on 27 August 2013

BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization

scientific article published on 11 May 2020

Basic Concepts of (Myocardial) Angiogenesis: Role of Vascular Endothelial Growth Factor and Angiopoietin.

scientific article

Basic and Therapeutic Aspects of Angiogenesis ⬇️

scientific article (publication date: 16 September 2011)

Basic and Therapeutic Aspects of Angiogenesis Updated

scientific article published on 02 July 2020

Bevacizumab and micrometastases: revisiting the preclinical and clinical rollercoaster

scientific article published on 27 September 2013

Biological Effects of Disruption of the Tissue‐Type Plasminogen Activator, Urokinase‐Type Plasminogen Activator, and Plasminogen Activator Inhibitor‐1 Genes in Micea ⬇️

scientific article published on January 17, 1995

Blockade of Myeloid-Derived Suppressor Cell Expansion with All-Trans Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy

scientific article published on 19 April 2018

Blood vessels and nerves: common signals, pathways and diseases

scientific article

Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium

scientific article

Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis

scientific article

Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis

scientific article published in April 2013

Bone marrow transplantation abolishes inhibition of arteriogenesis in placenta growth factor (PlGF) -/- mice

scientific article

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way.

scientific article published on June 2009

Bridges that guide and unite

scientific article published in Nature

Building in resistance to endothelial cell death

scientific article published on 01 November 2007

CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells

scientific article

CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions

scientific article

COVID-19: the vasculature unleashed

scientific article published on 21 May 2020

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets

scientific article published on 01 June 2018

CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers.

scientific article published in January 2005

Carbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) suppression

scientific article published on 14 October 2011

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha

scientific journal article

Cardiac Microvascular Endothelial Cells in Pressure Overload–Induced Heart Disease

scientific article

Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling

scientific article published in April 2002

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

scientific article published on March 2017

Cerebrovascular disorders: molecular insights and therapeutic opportunities

scientific article published on 26 October 2011

Chloroquine anticancer activity is mediated by autophagy-independent effects on the tumor vasculature

scientific article published on 9 December 2015

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

scientific journal article

Cloning and characterization of a cDNA encoding murine coagulation factor X.

scientific article

Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation

scientific article published on 31 October 2019

Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds

scientific article published on 31 July 2015

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

scientific article published in September 2021

Common mechanisms of nerve and blood vessel wiring

scientific article

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy

scientific article

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Control of vessel sprouting by genetic and metabolic determinants.

scientific article published on 27 September 2013

Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition ⬇️

scientific article published on September 1, 1998

Correction: MOSAIC: A Multiscale Model of Osteogenesis and Sprouting Angiogenesis with Lateral Inhibition of Endothelial Cells.

scientific article published on 28 March 2013

Corrigendum: PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin

scientific article published on 01 May 2015

Creating unique blood vessels

scientific article published in Nature

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin

scientific article

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis

scientific article

DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance

scientific article published on 27 July 2020

DOT1L safeguards cartilage homeostasis and protects against osteoarthritis.

scientific article

De novo design of a biologically active amyloid. ⬇️

scientific article

De novo vasculogenesis in the heart

scientific article

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

scholarly article by Bàrbara Laviña published in May 2018

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

scientific article published on 01 March 2022

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia.

scientific article published on 28 April 2016

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

scientific article

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

scientific article

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism

scientific article published on 06 January 2016

Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

scientific article published on 01 August 2004

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

scientific article published on 12 July 2010

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling

scientific article

Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin

scientific article

Differentiation but not ALS mutations in FUS rewires motor neuron metabolism

scientific article published on 12 September 2019

Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility

scientific article

Dose-dependent modulation of choroidal neovascularization by plasminogen activator inhibitor type I: implications for clinical trials

scientific article published in June 2003

Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis

scientific article

Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications

scientific article published on 01 June 2005

Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects

scientific article

Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes.

scientific article

Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice

scientific article published in March 2003

Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis

scientific article published on 11 November 2016

Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice

scientific article

Effects of Disruption of The Plasminogen Gene on Thrombosis, Growth, and Health in Mice ⬇️

scientific article published on November 1, 1995

Effects of placental growth factor deficiency on behavior, neuroanatomy, and cerebrovasculature of mice

scientific article published on 17 August 2018

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

scientific article published on 01 October 2004

Elevated levels of placental growth factor represent an adaptive host response in sepsis

scientific article published on 13 October 2008

Emerging Concepts in Organ-Specific Lymphatic Vessels and Metabolic Regulation of Lymphatic Development

scientific article published on 01 May 2018

Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes

scientific article

EndoDB: a database of endothelial cell transcriptomics data

scientific article

Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow

scientific article published on 25 March 2016

Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice.

scientific article

Endothelial Barrier and Metabolism: New Kids on the Block Regulating Bone Marrow Vascular Niches

Endothelial Cell Metabolism in Health and Disease

scientific article

Endothelial Cell Metabolism.

scientific article published in January 2018

Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization

scientific article published on 01 June 2020

Endothelial Metabolism Driving Angiogenesis: Emerging Concepts and Principles

scientific article published on July 2015

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

scientific article

Endothelial cell differentiation by SOX17: promoting the tip cell or stalking its neighbor instead?

scientific article published on 01 July 2014

Endothelial cell metabolism in health and disease: impact of hypoxia.

scientific article

Endothelial cell metabolism in normal and diseased vasculature

scientific article

Endothelial cell metabolism: A novel player in atherosclerosis? Basic principles and therapeutic opportunities

scientific article

Endothelial cell metabolism: an update anno 2017.

scientific article published on 15 February 2017

Endothelial cell metabolism: parallels and divergences with cancer cell metabolism

scientific article

Endothelial cells and cancer cells: metabolic partners in crime?

scientific article published on May 2015

Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.

scientific article published on 20 May 2009

Engineering vascularized bone: osteogenic and proangiogenic potential of murine periosteal cells

scientific article published in November 2012

Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas

scientific article published on 31 August 2010

Erratum: Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells

scientific article published in Nature

Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

scientific article published in Nature

Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells

scientific article published on 11 July 2006

Extra-intestinal calcium handling contributes to normal serum calcium levels when intestinal calcium absorption is suboptimal

scientific article published on 28 August 2015

FAF1, a gene that is disrupted in cleft palate and has conserved function in zebrafish

scientific article

FGF-dependent metabolic control of vascular development

scientific article published on 3 May 2017

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

scientific article published on December 2008

FOXO1 couples metabolic activity and growth state in the vascular endothelium

scientific article published on 06 January 2016

Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit

scientific article

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

scientific article published on 01 May 2018

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

scientific article published on April 2015

Fibrin-induced skin fibrosis in mice deficient in tissue plasminogen activator

scientific article

Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway

scientific article published in July 2008

Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation

scientific article published on 22 November 2008

Fibroblast growth factor signaling affects vascular outgrowth and is required for the maintenance of blood vessel integrity

scientific article published on 4 September 2014

Fishing and frogging for anti-angiogenic drugs

scientific article published on 01 May 2006

Food-restriction in obese dyslipidaemic diabetic mice partially restores basal contractility but not contractile reserve

scientific article published on December 2009

From vessel sprouting to normalization: role of the prolyl hydroxylase domain protein/hypoxia-inducible factor oxygen-sensing machinery.

scientific article published on 21 October 2010

Fumarase tumor suppressor gene and MET oncogene cooperate in upholding transformation and tumorigenesis.

scientific article published on 30 March 2010

Function of the Plasminogen/Plasmin and Matrix Metalloproteinase Systems After Vascular Injury in Mice With Targeted Inactivation of Fibrinolytic System Genes ⬇️

scientific article published on July 1, 1998

Functional reprogramming of regulatory T cells in the absence of Foxp3

scientific article published on 05 August 2019

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

article

G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway

scientific article

Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease.

scientific article

Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.

scientific article published on May 2008

Gas6 is dispensable for pubertal mammary gland development

scientific article published in PLoS ONE

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.

scientific article published on 21 December 2007

Gas6 protein: its role in cardiovascular calcification

scientific article

Gene prioritization through genomic data fusion

scientific article published in May 2006

Gene targeting and gene transfer to unravel the molecular basis of the formation and disorders of blood vessels

scientific article

Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture

scientific article

Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

article

Genetic deletion of placenta growth factor in mice alters uterine NK cells

scientific article

Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?

scientific article published on March 2004

Genetic evidence for a tumor suppressor role of HIF-2alpha.

scientific article published in August 2005

Genetic markers of bevacizumab-induced hypertension

scientific article published on 21 February 2014

Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy

scientific article published on 11 July 2014

Genetics in zebrafish, mice, and humans to dissect congenital heart disease: insights in the role of VEGF.

scientific article

Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis

scientific article published on December 2008

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium

scientific article published on 15 July 2019

Glutamine Metabolism Controls Chondrocyte Identity and Function

scientific article published on 22 May 2020

Glutamine metabolism in osteoprogenitors is required for bone mass accrual and PTH-induced bone anabolism in male mice

scientific article published on 30 November 2020

Glycolytic regulation of cell rearrangement in angiogenesis.

scientific article

Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.

scientific article published on 29 June 2009

Guidance of vascular and neural network formation

scientific article

HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

scientific article published in February 2016

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

scientific article published on 16 January 2019

HIF1 activity in granulosa cells is required for FSH-regulated Vegfa expression and follicle survival in mice

scientific article published on 22 May 2014

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

scientific article

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

scientific article published on 16 December 2016

Hallmarks of Endothelial Cell Metabolism in Health and Disease

scientific article published on 01 September 2019

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

scientific article published on 09 January 2020

Hepatocyte growth factor acts as a motogen and guidance signal for gonadotropin hormone-releasing hormone-1 neuronal migration

scientific article

Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity

scientific article

Heterogeneity in motoneuron disease

scientific article published on 06 September 2007

Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility

scientific article published on 01 July 2020

Heterogeneous vascular dependence of tumor cell populations

scientific article published in April 2001

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

scientific article

Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

scientific article

High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate

scientific article

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

scientific article published on 01 June 2021

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways

scientific article published on 9 November 2015

Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

scientific article published on 2 January 2016

Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020

Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.

scientific article

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

scientific article published on 01 September 2004

How Endothelial Cells Adapt Their Metabolism to Form Vessels in Tumors

scientific article published on 11 December 2017

How glucose, glutamine and fatty acid metabolism shape blood and lymph vessel development

scientific article published on 7 December 2017

How to Cross the Lymphatic Fence: Lessons From Solute Transport

scientific article published on 01 April 2017

How to teach an old dog new tricks: autophagy-independent action of chloroquine on the tumor vasculature

scientific article published on January 2014

Hungry for blood vessels: linking metabolism and angiogenesis

scientific article published in March 2008

Hyperthermia inhibits angiogenesis by a plasminogen activator inhibitor 1-dependent mechanism

scientific article published on 01 April 2003

Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation

scientific article

Hypoxia and inflammation

scientific article published on February 2011

Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

scientific article published on 2 January 2014

Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences

scientific article

Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation

scientific article

Hypoxia-ischemia or excitotoxin-induced tissue plasminogen activator- dependent gelatinase activation in mice neonate brain microvessels

scientific article

Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche

scientific article published on 13 June 2011

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

scientific article published on 01 July 2019

Identification of miR-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 and PKM2.

scientific article published on 26 September 2017

Immaturity of microvessels in haemorrhagic plaques is associated with proteolytic degradation of angiogenic factors

scientific article published on 01 January 2010

Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery

scientific article published on 06 July 2010

Impaired adipose tissue development in mice with inactivation of placental growth factor function

scientific article published on October 2006

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

scientific article published in February 2002

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

scientific journal article

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata

scientific journal article

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

scientific article published on 23 August 2018

Implication of the hypoxia response element of the Vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development

scientific article published in March 2006

Improved metabolite identification with MIDAS and MAGMa through MS/MS spectral dataset-driven parameter optimization

scientific article published in 2016

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

scientific article

Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?

scientific article

Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?

scientific article published on 13 December 2013

Increased Expression of Syndecan-1 Protects Against Cardiac Dilatation and Dysfunction After Myocardial Infarction

Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart

scientific article published on 15 August 2005

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

scientific article

Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization

scientific article

Influences of placental growth factor on mouse retinal vascular development.

scientific article

Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction

scientific article

Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury

scientific article published on January 2008

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

scientific article

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice

scientific article

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

scientific article published on 8 November 2016

Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model

scientific article published in September 2012

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

scientific article

Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis

scientific article

Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice

scientific article

Integrin indecision ⬇️

scientific article published on January 1, 2002

Interaction of endothelial cells with macrophages-linking molecular and metabolic signaling

scientific article published on 24 February 2017

Involvement of placental growth factor in Wallerian degeneration

scientific article

Involvement of u‐PA in the anti‐apoptotic activity of TGFβ for vascular smooth muscle cells ⬇️

scientific article published on August 25, 1997

Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability

scientific article published on 19 August 2010

Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice.

scientific article published in March 2002

Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation

scientific article published on 08 August 2019

Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?

scientific article published on 29 November 2010

Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin.

scientific article published on 30 October 2003

Lipid availability determines fate of skeletal progenitor cells via SOX9

scientific article published on 26 February 2020

Live imaging reveals a conserved role of fatty acid β-oxidation in early lymphatic development in zebrafish

scientific article published on 19 June 2018

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

scientific journal article

Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.

scientific article

Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth

scientific article published in March 2004

Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice.

scientific article

Loss of placental growth factor protects mice against vascular permeability in pathological conditions

scientific article

Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function

scientific article published on 30 June 2010

Loss of the VEGF(164) and VEGF(188) isoforms impairs postnatal glomerular angiogenesis and renal arteriogenesis in mice

scientific article published in June 2002

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.

scientific article

Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia

scientific article published on 01 January 2020

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

scientific article published on June 2011

Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice

scientific article published on January 2005

Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

scientific article published on 8 October 2009

Low expression VEGF haplotype increases the risk for tetralogy of Fallot: a family based association study

scientific article

Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies

scientific article published on 12 March 2020

Lymph makes you fat

scientific article published on 01 October 2005

MOSAIC: a multiscale model of osteogenesis and sprouting angiogenesis with lateral inhibition of endothelial cells

scientific article

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

scientific article

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

scientific article published on 28 October 2020

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.

scientific article published on 20 November 2009

Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers-A New Perspective?

scientific article published on July 2016

Manipulating angiogenesis in medicine

scientific article published on May 2004

Markers of response for the antiangiogenic agent bevacizumab

scientific article published on 11 February 2013

Matricellular proteins and matrix metalloproteinases mark the inflammatory and fibrotic response in human cardiac allograft rejection

scientific article

Matrix deformations around angiogenic sprouts correlate to sprout dynamics and suggest pulling activity

scientific article published on 29 January 2020

Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase

scientific article

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

scientific article published on 01 November 2010

Mechanisms of angiogenesis and arteriogenesis

scientific article (publication date: April 2000)

Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates

scientific article

Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way.

scientific article published on 05 March 2009

Medicine: genetic spotlight on a blood defect

scientific article published in February 2004

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

scientific article

Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake

scientific article published on 5 January 2015

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

scientific article published on 06 September 2016

Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype

scientific article published on 15 April 2008

Metabolic Pathways Fueling the Endothelial Cell Drive

scientific article published on 01 February 2019

Metabolic Signatures of Distinct Endothelial Phenotypes

scientific article published on 01 July 2020

Metabolic adaptations in diabetic endothelial cells

scientific article

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

scientific article published on 25 April 2019

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

scientific article published on 01 June 2019

Metabolic control of the cell cycle.

scientific article

Metabolic pathway compartmentalization: an underappreciated opportunity?

scientific article

Metabolism and therapeutic angiogenesis

scientific article published on 01 June 2008

Metabolism of stromal and immune cells in health and disease

scientific article published on July 2014

Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance

scientific article

Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization

scientific article

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

scientific article

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation

scientific article published on 20 November 2014

Modeling lymphangiogenesis in a three-dimensional culture system

scientific article published on 20 April 2008

Modification of K channel inactivation by papain and N-bromoacetamide

scientific article

Modification of kidney barrier function by the urokinase receptor

scientific article published on 16 December 2007

Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling

Molecular analysis of blood vessel formation and disease ⬇️

scientific article published on November 1, 1997

Molecular basis of angiogenesis. Role of VEGF and VE-cadherin.

scientific article

Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling

scientific article

Molecular mechanisms and clinical applications of angiogenesis

scientific article (publication date: 19 May 2011)

Molecular mechanisms of blood vessel growth

scientific article

Molecular mechanisms of lymphangiogenesis in health and disease

scientific article

Mouse aortic ring assay: A new approach of the molecular genetics of angiogenesis

scientific article

Mouse models of angiogenesis, arterial stenosis, atherosclerosis and hemostasis ⬇️

scientific article published on July 1, 1998

Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression

scientific article published on 22 March 2016

Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

scientific article published on March 2017

Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice

scientific article

NKT cell-derived urokinase-type plasminogen activator promotes peripheral tolerance associated with eye.

scientific article published in August 2007

Neonatal hypoxic preconditioning involves vascular endothelial growth factor

scientific article published on 13 January 2007

Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex

scientific article published on 17 November 2016

Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons

scientific article published on 19 January 2011

Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues

scientific journal article

Neuroprotection by urokinase plasminogen activator in the hippocampus

scientific article published on 24 January 2012

Neurovascular signalling defects in neurodegeneration

scientific article published on March 2008

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

scientific article published on 01 December 2020

Nogo-A regulates vascular network architecture in the postnatal brain

scientific article published on 10 November 2016

Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

scientific article

Novel mutation in the Per-Arnt-Sim domain of KCNH2 causes a malignant form of long-QT syndrome.

scientific article published on 7 February 2005

Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death

scientific article

Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration

scientific article

Novel transgenic rabbit model sheds light on the puzzling role of matrix metalloproteinase-12 in atherosclerosis

scientific article published on 01 April 2006

NuSAP is essential for chromatin-induced spindle formation during early embryogenesis ⬇️

scientific article published on August 31, 2010

Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C

scientific article published on 01 February 1998

Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages

scientific article published on 17 July 2017

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin.

scientific article published on 2 July 2018

Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish

article by Robin Lemmens et al published 17 July 2007 in Human Molecular Genetics

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

scientific article

Ovulation efficiency is reduced in mice that lack plasminogen activator gene function: functional redundancy among physiological plasminogen activators

scientific article

Oxygen sensing: a common crossroad in cancer and neurodegeneration

scientific article published on January 2010

Oxygen sensors at the crossroad of metabolism

scientific article published on January 2009

Oxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administration

scientific article

PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin.

scientific article

PAR1 contributes to influenza A virus pathogenicity in mice

scientific article

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

scientific article published on 10 January 2020

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

scientific article published in 2022

PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production

scientific article published on 21 October 2019

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development

scientific article

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.

scientific article

Paracrine control of vascular innervation in health and disease ⬇️

scientific article published on July 30, 2011

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

scientific article published on 12 December 2013

Pericytes: blood-brain barrier safeguards against neurodegeneration?

scientific article published on 01 November 2010

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation

scientific article published on 15 June 2013

Peroxisome deficient aP2-Pex5 knockout mice display impaired white adipocyte and muscle function concomitant with reduced adrenergic tone

scientific article published on 22 October 2012

Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers

scientific article published on 21 October 2011

Phenotype molding of stromal cells in the lung tumor microenvironment

scientific article published on 09 July 2018

Physiological consequences of loss of plasminogen activator gene function in mice

scientific article published in Nature

PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge

scientific article published on 30 November 2011

PlGF repairs myocardial ischemia through mechanisms of angiogenesis, cardioprotection and recruitment of myo-angiogenic competent marrow progenitors

scientific article

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity

scientific article published on 09 February 2016

PlGF: a multitasking cytokine with disease-restricted activity

scientific article published on August 2012

Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.

scientific article published on 21 December 2015

Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders

scientific article (publication date: December 2002)

Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma.

scientific article published on 20 January 2012

Placental growth factor deficiency is associated with impaired cerebral vascular development in mice

scientific article published on 7 December 2015

Placental growth factor in cancer

scientific article

Placental growth factor influences maternal cardiovascular adaptation to pregnancy in mice

scientific article published on 23 December 2014

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

scientific article published on 11 January 2016

Placental growth factor mediates aldosterone-dependent vascular injury in mice

scientific article

Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair

scientific article published on 13 April 2006

Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation

scientific article

Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism

scientific article

Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization

scientific article

Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo

scientific journal article

Plasmin is not protective in experimental renal interstitial fibrosis

scientific article

Plasmin therapy enhances mobilization of HPCs after G-CSF

scientific article published on 22 August 2008

Plasminogen activator inhibitor 1 and vitronectin protect against stenosis in a murine carotid artery ligation model

scientific article published on 01 December 2002

Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

scientific article

Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia

scientific article published on 17 April 2003

Plasminogen activator inhibitor-1 gene deficiency attenuates TGF-beta1-induced kidney disease

scientific article published on 01 December 2005

Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis

scientific article published on June 2003

Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling

scientific article published on June 2009

Plasminogen and cell migration in vivo

scholarly article

Plasminogen controls inflammation and pathogenesis of influenza virus infections via fibrinolysis

scientific article

Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice ⬇️

scientific article published on March 15, 1998

Plasminogen mediates liver regeneration and angiogenesis after experimental partial hepatectomy ⬇️

scientific article published on 01 November 2003

Prevalence of prostate cancer metastases after intravenous inoculation provides clues into the molecular basis of dormancy in the bone marrow microenvironment.

scientific article

Prevention of elastase-induced emphysema in placenta growth factor knock-out mice

scientific article

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

scientific article published on June 2011

Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

scientific article

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

scientific article published on 31 March 2008

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

scientific article published on 14 August 2017

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

scientific article published on 7 February 2011

Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.

scientific article published on 26 April 2016

Prominin-1 allows prospective isolation of neural stem cells from the adult murine hippocampus.

scientific article

Prominin-1 controls stem cell activation by orchestrating ciliary dynamics

scientific article published on 06 December 2018

Protective Role of Reactive Astrocytes in Brain Ischemia

scientific article published on 29 August 2007

Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours

scientific article

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

scientific article published on 14 September 2021

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis

scientific article published on 28 July 2021

Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver

scientific article published on 01 May 2021

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis ⬇️

scientific article published on 23 August 2018

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

scientific article published on August 2013

Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice ⬇️

scientific article published on January 12, 1998

Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis

scientific article

Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration

scientific article

Reduction in arthritis severity and modulation of immune function in tissue factor cytoplasmic domain mutant mice

scientific article

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium

scientific article published on 29 May 2008

Regulation of Arterial Thrombolysis by Plasminogen Activator Inhibitor-1 in Mice ⬇️

scientific article published on March 17, 1998

Regulation of angiogenesis by oxygen and metabolism.

scientific article published on February 2009

Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

scientific article

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

scientific article published on 08 February 2016

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

scientific article

Renal metabolism in 2017: Glycolytic adaptation and progression of kidney disease

scientific article published on 18 December 2017

Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors

scientific article published on January 2005

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

scientific article

Role and therapeutic potential of VEGF in the nervous system

scientific article published on April 2009

Role and therapeutic potential of dietary ketone bodies in lymph vessel growth

scientific article published on 12 July 2019

Role of Gas-6 in adipogenesis and nutritionally induced adipose tissue development in mice

scientific article published on 24 February 2005

Role of Gas6 in erythropoiesis and anemia in mice

scientific journal article

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy

scientific journal article

Role of PFKFB3-driven glycolysis in vessel sprouting

scientific article

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

scientific article

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

scientific article

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.

scientific article published on 13 May 2010

Role of endothelial cell metabolism in vessel sprouting.

scientific article published on 22 August 2013

Role of glutamine and interlinked asparagine metabolism in vessel formation ⬇️

scientific article published on 28 June 2017

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis ⬇️

scientific article published in Nature

Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning

scientific article published on 17 October 2013

Role of hypoxia inducible factors 1alpha and 2alpha in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice

scientific article

Role of neural guidance signals in blood vessel navigation

scientific article

Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension

scientific article published on 12 September 2009

Role of synectin in lymphatic development in zebrafish and frogs

scientific article published on 14 July 2010

Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity

scientific article published on 14 May 2020

Role of the plasminogen system in basal adhesion formation and carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice

scientific article published on 01 July 2003

Role of the plasminogen/plasmin system in thrombosis, hemostasis, restenosis and atherosclerosis evaluation in transgenic animals ⬇️

scientific article published on 01 July 1995

Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions

scientific article published in January 2004

Role of vascular endothelial growth factor and placental growth factor in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice

scientific article

Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models

scientific article published on 14 March 2013

Role of vascular endothelial growth factor receptor 1 in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in mice

scientific article published on 01 October 2004

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

scientific article

Sculpting heart valves with NFATc and VEGF.

scientific article published in September 2004

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.

scientific article published on 15 February 2017

Selective regulation of arterial branching morphogenesis by synectin

scientific article published in June 2006

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

article

Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice

scientific article published on 17 March 2017

Shaping the brain vasculature in development and disease in the single-cell era

scientific article published in 2023

Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis

scientific article published on 12 December 2019

Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions

scientific article published on 01 December 2009

Signalling silenced

scientific article published in Nature

Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited

scientific article published on March 2009

Similarities between angiogenesis and neural development: what small animal models can tell us.

scientific article published on January 2008

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

scientific article published on 01 April 2020

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

scientific article published on 09 December 2019

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

scientific article published on 13 February 2020

Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis

scientific article

SnapShot: Tumor angiogenesis

scientific article published on 01 June 2012

Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival

scientific journal article

Soluble VEGF receptor Flt1: the elusive preeclampsia factor discovered?

scientific article

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association

scientific article

Stem Cell-Derived Photoreceptor Transplants Differentially Integrate Into Mouse Models of Cone-Rod Dystrophy.

scientific article published on June 2016

Stem cell marker prominin-1 regulates branching morphogenesis, but not regenerative capacity, in the mammary gland

scientific article

Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice

scientific article published in April 2003

Stromal Gas6 promotes the progression of premalignant mammary cells

scientific article published on 07 December 2018

Structure-function analyses of thrombomodulin by gene-targeting in mice: the cytoplasmic domain is not required for normal fetal development

scientific article

Successful double-lung transplantation from a donor previously infected with SARS-CoV-2

scientific article published on 01 December 2020

Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

scientific article published on 4 January 2011

Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy

scientific article published on 25 June 2012

Systemic sclerosis-like histopathological features in the myocardium of uPAR-deficient mice

scientific article published on 12 August 2015

TRPA1 underlies a sensing mechanism for O2.

scientific article

Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting

scientific article published on April 2013

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

scientific article (publication date: 23 July 1999)

Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development

scientific journal article

Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential.

scientific article published on 14 January 2014

Targeting angiogenic metabolism in disease

scientific article

Targeting endothelial metabolism for anti-angiogenesis therapy: A pharmacological perspective

scientific article published on 7 January 2017

Targeting fatty acid metabolism in cancer and endothelial cells

scientific article

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma

scientific article published on February 2013

Testosterone suppresses protective responses of the liver to blood-stage malaria

scientific article

Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform

scientific article published in March 2007

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

scientific article published on 28 July 2015

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.

scientific article

The European dimension for the mouse genome mutagenesis program

scientific article

The FGF system has a key role in regulating vascular integrity

scientific article published on October 2008

The FGF system has a key role in regulating vascular integrity.

scientific article

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

scientific article published on 2 April 2014

The Link Between Angiogenesis and Endothelial Metabolism

scientific article published on 15 December 2016

The NADPH oxidase Nox2 regulates VEGFR1/CSF-1R-mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex

scientific article

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

scientific article published on 8 March 2016

The PHD2 oxygen sensor paves the way to metastasis

scientific article published on 21 October 2015

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

scientific article published in May 2018

The cytoplasmic domain of tissue factor contributes to leukocyte recruitment and death in endotoxemia

scientific article

The diversity of endothelial cells: a challenge for therapeutic angiogenesis

scientific article

The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation

scientific article published on 16 September 2013

The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis.

scientific article

The interferon inducer ampligen [poly(I)-poly(C12U)] markedly protects mice against coxsackie B3 virus-induced myocarditis

scientific article published on January 2004

The metabolic engine of endothelial cells

scientific article published on 30 September 2019

The multifaceted activity of VEGF in angiogenesis - Implications for therapy responses

scientific article

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system

scientific article published on 27 October 2004

The neurovascular link in health and disease: an update

scientific article published on 02 October 2009

The neurovascular link in health and disease: molecular mechanisms and therapeutic implications

scientific article published on August 2011

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

scientific journal article

The pathophysiology of pelvic floor disorders: evidence from a histomorphologic study of the perineum and a mouse model of rectal prolapse ⬇️

scientific article published on 01 November 2001

The placental growth factor as a target against hepatocellular carcinoma in a diethylnitrosamine-induced mouse model

scientific article published on 6 October 2012

The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies

scientific article

The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent

scientific journal article

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

scientific article

The role of fatty acid β-oxidation in lymphangiogenesis

scientific article published on 26 December 2016

The role of the VEGF-isoforms in pathological choroidal/retinal angiogenesis

scientific article published on 01 January 2011

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

scientific article published on 5 May 2008

The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress

scientific article published on 19 February 2008

The zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells.

scientific article

Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain

scientific article

Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells

scientific article published on 02 February 2012

Tissue plasminogen activator arrests Alzheimer's disease pathogenesis

scientific article published on 12 October 2013

Transcription factor COUP-TFII is indispensable for venous and lymphatic development in zebrafish and Xenopus laevis

scientific article published on 27 May 2011

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

scientific journal article

Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotype

scientific article published on 12 November 2020

Transient reduction of placental angiogenesis in PAI-1-deficient mice

scientific journal article

Treating Diabetes by Blocking a Vascular Growth Factor ⬇️

scientific article published on 01 November 2012

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

scientific article

Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination

scientific article

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

scientific article

Tumor vessel disintegration by maximum tolerable PFKFB3 blockade

scientific article published on 5 September 2017

Tumor vessel normalization by chloroquine independent of autophagy.

scientific article published on August 2014

Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I.

scientific article

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

scientific article published on 17 August 2016

Type 1 plasminogen activator inhibitor deficiency aggravates the course of experimental glomerulonephritis through overactivation of transforming growth factor beta

scientific article published on 01 August 2003

Unconventional intronic splice site mutation in SCN5A associates with cardiac sodium channelopathy

scientific article

Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences

scientific article

Urokinase and Tissue-type Plasminogen Activator Are Required for the Mitogenic and Chemotactic Effects of Bovine Fibroblast Growth Factor and Platelet-derived Growth Factor-BB for Vascular Smooth Muscle Cells ⬇️

scientific article published on September 19, 1997

Urokinase but Not Tissue Plasminogen Activator Mediates Arterial Neointima Formation in Mice ⬇️

scientific article published on November 1, 1997

Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy

scientific article published in May 2003

Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia

scientific article published in April 2002

Urokinase receptor modulates cellular and angiogenic responses in obstructive nephropathy

scientific article published in May 2003

Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis

scientific article

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation ⬇️

scientific article published on December 1, 1997

Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm

scientific article published on 13 February 2003

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

scientific article

VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization

scientific article published on 5 June 2006

VEGF and PlGF: two pleiotropic growth factors with distinct roles in development and homeostasis

scientific article

VEGF as a key mediator of angiogenesis in cancer

scientific article

VEGF at the neurovascular interface: therapeutic implications for motor neuron disease

scientific article

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

scientific article published in May 2004

VEGF inhibitors make blood

scientific article published on 01 July 2006

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

scientific article published in August 2003

VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration

scientific article published on 12 March 2013

VEGF mediates commissural axon chemoattraction through its receptor Flk1.

scientific article published on June 2011

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

scientific article

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

scientific article

VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis

scientific article published on 6 May 2010

VEGF receptor-2 (Flk-1) overexpression in mice counteracts focal epileptic seizures

scientific article

VEGF-B Improves Metabolic Health through Vascular Pruning of Fat.

scientific article published in April 2016

VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain

scientific article

VEGF-D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis.

scientific article published in November 2009

VEGF: a critical player in neurodegeneration

scientific article published on January 2004

VEGF: a modifier of the del22q11 (DiGeorge) syndrome?

scientific article published on 21 January 2003

VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS?

scientific article published on June 2004

VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

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VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism

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VEGFR-2-mediated increased proliferation and survival in response to oxygen and glucose deprivation in PlGF knockout astrocytes

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Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

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Vascular Endothelial Growth Factor Up-regulation in Human Amniotic Fluid Stem Cell Enhances Nephroprotection After Ischemia-Reperfusion Injury in the Rat.

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Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders

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Vascular development and disorders: Molecular analysis and pathogenic insights ⬇️

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Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality

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Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation

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Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms

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Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord

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Vascular endothelial growth factor: a neurovascular target in neurological diseases

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Vascular progenitors: from biology to treatment

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Vascular remodeling in mice lacking the cytoplasmic domain of tissue factor

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Vessel abnormalization: another hallmark of cancer? Molecular mechanisms and therapeutic implications

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Vessel pruning or healing: endothelial metabolism as a novel target?

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Vessels of Death or Life

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Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism

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Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

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Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways

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Zebrafish and Xenopus tadpoles: small animal models to study angiogenesis and lymphangiogenesis

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[New non-metabolic role for glutamine synthetase in angiogenesis]

scientific article published on 22 May 2019

c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

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uPA deficiency exacerbates muscular dystrophy in MDX mice

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uPA deficiency exacerbates muscular dystrophy inMDXmice

scholarly article by Mònica Suelves et al published 8 October 2007 in Journal of Cell Biology

uPAR: a versatile signalling orchestrator

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