List of works - Joachim P. Spatz

A photoactivatable nanopatterned substrate for analyzing collective cell migration with precisely tuned cell-extracellular matrix ligand interactions

scientific article

A unique profilin-actin interface is important for malaria parasite motility

scientific article

Actin fusion proteins alter the dynamics of mechanically induced cytoskeleton rearrangement

scientific article

Adhesion Stabilized en Masse Intracellular Electrical Recordings from Multicellular Assemblies

scientific article published on 12 April 2019

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα.

scientific article

An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

scientific article published on 24 January 2020

Author Correction: An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

scientific article published on 31 March 2020

Biomimetic F-actin cortex models

scientific article

Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids

scientific article

Bottom-up assembly of biomedical relevant fully synthetic extracellular vesicles

scientific article published on 03 September 2021

Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches

scientific article published on 24 June 2008

Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules

scientific article

Cell interactions with hierarchically structured nano-patterned adhesive surfaces.

scientific article

Cell-Extracellular Matrix Mechanobiology: Forceful Tools and Emerging Needs for Basic and Translational Research

scientific article published on 27 November 2017

Circular, nanostructured and biofunctionalized hydrogel microchannels for dynamic cell adhesion studies

scientific article

Cooperativity in adhesion cluster formation during initial cell adhesion

scientific article

Coupling of Retrograde Flow to Force Production During Malaria Parasite Migration

scientific article published on 20 January 2016

Cyclic stretch increases splicing noise rate in cultured human fibroblasts

scientific article

Cyclic tensile strain controls cell shape and directs actin stress fiber formation and focal adhesion alignment in spreading cells

scientific article

Depending on its nano-spacing, ALCAM promotes cell attachment and axon growth

scientific article (publication date: 2012)

Differential Modulation of Platelet Adhesion and Spreading by Adhesive Ligand Density

scientific article published on 11 February 2019

Direct manipulation of malaria parasites with optical tweezers reveals distinct functions of Plasmodium surface proteins

scientific article

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography ⬇️

scientific article published on August 8, 2010

Elastic moduli of living epithelial pancreatic cancer cells and their skeletonized keratin intermediate filament network

scientific article

Environmental constraints guide migration of malaria parasites during transmission

scientific article

Extracellular-matrix tethering regulates stem-cell fate

scientific article

Fluorescence of dyes adsorbed on highly organized, nanostructured gold surfaces

scientific article

Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding

scientific article

Forces during cellular uptake of viruses and nanoparticles at the ventral side

scientific article published on 02 January 2020

Genome function and nuclear architecture: from gene expression to nanoscience

scientific article

Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy

scientific article published on 12 October 2009

Impact of local versus global ligand density on cellular adhesion.

scientific article published on 22 March 2011

Impact of order and disorder in RGD nanopatterns on cell adhesion

scientific article published on March 2009

Impact of tumor cell cytoskeleton organization on invasiveness and migration: a microchannel-based approach

scientific article

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

scientific article

Increasing the order parameter of quasi-hexagonal micellar nanostructures by ultrasound annealing

scientific article

Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing.

scientific article published on 18 June 2008

Integrin Subtypes and Nanoscale Ligand Presentation Influence Drug Sensitivity in Cancer Cells

scientific article published on 10 January 2020

Integrin-Assisted T-Cell Activation on Nanostructured Hydrogels.

scientific article published on 6 September 2017

Intermediate filament reorganization dynamically influences cancer cell alignment and migration

scientific article

Investigating cell-ECM contact changes in response to hypoosmotic stimulation of hepatocytes in vivo with DW-RICM

scientific article (publication date: 2012)

Lateral shear forces applied to cells with single elastic micropillars to influence focal adhesion dynamics

scientific article

Machine-Learning-Driven Surface-Enhanced Raman Scattering Optophysiology Reveals Multiplexed Metabolite Gradients Near Cells

scientific article published on 12 February 2019

MaxSynBio: Avenues Towards Creating Cells from the Bottom Up

MaxSynBio: Wege zur Synthese einer Zelle aus nicht lebenden Komponenten

Mechanical interactions among followers determine the emergence of leaders in migrating epithelial cell collectives

scientific article published in Nature Communications

Mechanical response analysis and power generation by single-cell stretching

scientific article

Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission

scientific article

Nanopatterned Adhesive, Stretchable Hydrogel to Control Ligand Spacing and Regulate Cell Spreading and Migration.

scientific article published on 11 July 2017

Nanoscale and mechanical properties of the physiological cell-ECM microenvironment

scientific article

Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation

scientific article

Optical force sensor array in a microfluidic device based on holographic optical tweezers

scientific article

Reconceptualizing Fluorescence Correlation Spectroscopy for Monitoring and Analyzing Periodically Passing Objects

scientific article

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly

scientific article published on 22 March 2016

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

scientific article published on 16 October 2017

Simulating different manufactured antireflective sub-wavelength structures considering the influence of local topographic variations

scientific article

Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells

scientific article

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

scientific article published on 11 January 2022

Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin

scientific article

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

scientific article published in May 2007

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

scientific article published on 14 February 2022

T cell activation is determined by the number of presented antigens ⬇️

scientific article published on 17 October 2013

Tailored antireflective biomimetic nanostructures for UV applications

scientific article

Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells

scientific article published on 29 April 2022

The kinetics of force-induced cell reorganization depend on microtubules and actin

scientific article published on April 2010

Titanium-silicon oxide film structures for polarization-modulated infrared reflection absorption spectroscopy

scientific article

Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates.

scientific article

List of works by Joachim P. Spatz

A photoactivatable nanopatterned substrate for analyzing collective cell migration with precisely tuned cell-extracellular matrix ligand interactions

A unique profilin-actin interface is important for malaria parasite motility

Actin fusion proteins alter the dynamics of mechanically induced cytoskeleton rearrangement

Adhesion Stabilized en Masse Intracellular Electrical Recordings from Multicellular Assemblies

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα.

An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

Author Correction: An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

Biomimetic F-actin cortex models

Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids

Bottom-up assembly of biomedical relevant fully synthetic extracellular vesicles

Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches

Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules

Cell interactions with hierarchically structured nano-patterned adhesive surfaces.

Cell-Extracellular Matrix Mechanobiology: Forceful Tools and Emerging Needs for Basic and Translational Research

Circular, nanostructured and biofunctionalized hydrogel microchannels for dynamic cell adhesion studies

Cooperativity in adhesion cluster formation during initial cell adhesion

Coupling of Retrograde Flow to Force Production During Malaria Parasite Migration

Cyclic stretch increases splicing noise rate in cultured human fibroblasts

Cyclic tensile strain controls cell shape and directs actin stress fiber formation and focal adhesion alignment in spreading cells

Depending on its nano-spacing, ALCAM promotes cell attachment and axon growth

Differential Modulation of Platelet Adhesion and Spreading by Adhesive Ligand Density

Direct manipulation of malaria parasites with optical tweezers reveals distinct functions of Plasmodium surface proteins

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography ⬇️

Elastic moduli of living epithelial pancreatic cancer cells and their skeletonized keratin intermediate filament network

Environmental constraints guide migration of malaria parasites during transmission

Extracellular-matrix tethering regulates stem-cell fate

Fluorescence of dyes adsorbed on highly organized, nanostructured gold surfaces

Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding

Forces during cellular uptake of viruses and nanoparticles at the ventral side

Genome function and nuclear architecture: from gene expression to nanoscience

Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy

Impact of local versus global ligand density on cellular adhesion.

Impact of order and disorder in RGD nanopatterns on cell adhesion

Impact of tumor cell cytoskeleton organization on invasiveness and migration: a microchannel-based approach

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

Increasing the order parameter of quasi-hexagonal micellar nanostructures by ultrasound annealing

Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing.

Integrin Subtypes and Nanoscale Ligand Presentation Influence Drug Sensitivity in Cancer Cells

Integrin-Assisted T-Cell Activation on Nanostructured Hydrogels.

Intermediate filament reorganization dynamically influences cancer cell alignment and migration

Investigating cell-ECM contact changes in response to hypoosmotic stimulation of hepatocytes in vivo with DW-RICM

Lateral shear forces applied to cells with single elastic micropillars to influence focal adhesion dynamics

Machine-Learning-Driven Surface-Enhanced Raman Scattering Optophysiology Reveals Multiplexed Metabolite Gradients Near Cells

MaxSynBio: Avenues Towards Creating Cells from the Bottom Up

MaxSynBio: Wege zur Synthese einer Zelle aus nicht lebenden Komponenten

Mechanical interactions among followers determine the emergence of leaders in migrating epithelial cell collectives

Mechanical response analysis and power generation by single-cell stretching

Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission

Nanopatterned Adhesive, Stretchable Hydrogel to Control Ligand Spacing and Regulate Cell Spreading and Migration.

Nanoscale and mechanical properties of the physiological cell-ECM microenvironment

Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation

Optical force sensor array in a microfluidic device based on holographic optical tweezers

Reconceptualizing Fluorescence Correlation Spectroscopy for Monitoring and Analyzing Periodically Passing Objects

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

Simulating different manufactured antireflective sub-wavelength structures considering the influence of local topographic variations

Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

T cell activation is determined by the number of presented antigens ⬇️

Tailored antireflective biomimetic nanostructures for UV applications

Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells

The kinetics of force-induced cell reorganization depend on microtubules and actin

Titanium-silicon oxide film structures for polarization-modulated infrared reflection absorption spectroscopy

Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates.