Search filters

List of works by Robin Lovell-Badge

A New Understanding, Guided by Single-Cell Sequencing, of the Establishment and Maintenance of the Ovarian Reserve in Mammals

scientific article published in 2022

A freeze-dryer and a fertile imagination ⬇️

scientific article published on July 1, 1998

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif ⬇️

scientific article published on July 19, 1990

A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells

scientific journal article

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

scientific article published in October 2002

A promoter trap in embryonic stem (ES) cells selects for integration of DNA into CpG islands ⬇️

scientific article published on January 11, 1991

A role for SOX1 in neural determination ⬇️

scientific article published on May 1, 1998

After the Storm - A Responsible Path for Genome Editing

scientific article published on 16 January 2019

Aggressive behaviour: contributions from genes on the Y chromosome.

scientific article

An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism

scientific article

Anne McLaren 1927-2007.

scientific article published in July 2007

Assisted reproductive technologies to prevent human mitochondrial disease transmission

scientific article published on 9 November 2017

Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis.

scientific article published on 9 January 2012

CRISPR babies: a view from the centre of the storm

scientific article published on 06 February 2019

CRISPR germline engineering--the community speaks

scientific article published on May 2015

CRISPR: A path through the thicket.

scientific article

Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice

scientific article published in 2012

Coordination of progenitor specification and growth in mouse and chick spinal cord

scientific article

Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone

scientific article published on February 2017

Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission

scientific article published on 01 July 2018

Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission.

scientific article published in February 2018

DNA Binding Activity of Recombinant SRY from Normal Males and XY Females ⬇️

scientific article published on January 24, 1992

Dax1 expression is dependent on steroidogenic factor 1 in the developing gonad

scientific article

Debate on Germline Gene Editing

scientific article published in August 2016

Dentate gyrus development requires a cortical hem-derived astrocytic scaffold

scientific article published on 04 January 2021

Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch

scientific article (publication date: 31 August 2010)

Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia

scientific article

Disruption of the LF-A1 and LF-B1 binding sites in the human alpha-1-antitrypsin gene has a differential effect during development in transgenic mice ⬇️

scientific article published on November 1, 1991

Early development of the pituitary gland: induction and shaping of Rathke's pouch.

scientific article

Erratum: Revisiting the Warnock rule.

scientific article published in December 2017

Error-prone ZW pairing and no evidence for meiotic sex chromosome inactivation in the chicken germ line

scientific article

Ethereal ethics

scientific article

Excess DAX1 Leads to XY Ovotesticular Disorder of Sex Development (DSD) in Mice by Inhibiting Steroidogenic Factor-1 (SF1) Activation of the Testis Enhancer ofSRY-box-9(Sox9)

scientific article published on 31 January 2012

Expression of Sry, the mouse sex determining gene ⬇️

scientific article published on June 1, 1995

Expression of the α-fetoprotein gene in pluripotent and committed cells ⬇️

scientific article published on November 22, 1984

Expression ofSox3 throughout the developing central nervous system is dependent on the combined action of discrete, evolutionarily conserved regulatory elements

article

Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations

scientific article

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

scientific article published in June 2006

Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination

scholarly article

Flexibility of neural stem cells

scientific article

Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue

scientific article published on 27 May 2009

Generation of purified neural precursors from embryonic stem cells by lineage selection ⬇️

scientific article published on August 27, 1998

Genetic regulation of pituitary gland development in human and mouse

scientific article

Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement.

scientific article published in December 2015

Gonadal asymmetry and sex determination in birds

scientific article published on 27 February 2014

Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination

scientific article published on 27 December 2018

High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response

scientific article published on 14 December 2017

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation

scientific article published in October 2017

Human-animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate

scientific article published in September 2007

Identification of SOX3 as an XX male sex reversal gene in mice and humans

scientific article

Imbalance between neutrophil elastase and its inhibitor α1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure

scientific article published on April 2013

Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline.

scientific article

Inference of gene-phenotype associations via protein-protein interaction and orthology

scientific article

Inverted repeat structure of the Sry locus in mice ⬇️

scientific article published on September 1, 1992

Involvement of SOX proteins in lens-specific activation of crystallin genes ⬇️

scientific article published on July 17, 1995

Involvement ofSox1, 2and3in the early and subsequent molecular events of lens induction ⬇️

scientific article published on July 1, 1998

Looking for the niche: substance delivery into the lateral ventricle of the brain: the osmotic minipump system

scientific article published on January 2013

Many ways to pluripotency

scientific article published in October 2007

Mechanisms of gonadal morphogenesis are not conserved between chick and mouse

scientific article published on 9 September 2006

Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand.

scientific article published on October 2013

Multipotent cell lineages in early mouse development depend on SOX2 function

scientific journal article

Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans

scientific journal article

NOTCH activity differentially affects alternative cell fate acquisition and maintenance.

scientific article published on 26 March 2018

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation

scientific article published on 18 October 2018

Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland.

scientific article

Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1

scientific article

Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

scientific article

Normal structure and expression of Zfy genes in XY female mice mutant in Tdy ⬇️

scientific article published on 01 July 1990

Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer

scientific article

Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis

scientific article published on 25 February 2020

Of sex and determination: marking 25 years of Randy, the sex-reversed mouse

scientific article published in May 2016

Oncogenicity of the developmental transcription factor Sox9.

scientific article

Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism

scientific article

PCR as a rapid screening method for transgenic mice

scientific article published on 01 November 1988

PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary

scientific article published on 24 October 2007

Paul S. Burgoyne (1946-2020)

scientific article published on 27 October 2020

Perspective on Stem Cells in Developmental Biology, with Special Reference to Neuroendocrine Systems

Pivotal role of median eminence tanycytes for hypothalamic function and neurogenesis

scientific article published on 13 August 2016

Pluripotent stem cell-derived gametes: truth and (potential) consequences

scientific article published on July 2009

Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse

scientific article

RNA FISH, DNA FISH and Chromosome Painting of Chicken Oocytes

scientific article published on January 2016

Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation

scientific article published on September 2011

Regenerative Medicine: Organ recital in a dish

scientific article published on 30 November 2011

Regionalization of the nervous system requires axial allocation prior to neural lineage commitment

Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast.

scientific article published on 6 February 2014

Revisiting the Warnock rule.

scientific article

SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary

scientific article published on 25 May 2016

SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development

scientific article

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.

scientific article

SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis

scientific journal article

SOX3 is required during the formation of the hypothalamo-pituitary axis

scientific journal article

SOX3 promotes generation of committed spermatogonia in postnatal mouse testes

scientific article published on 21 April 2020

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

scientific article published in 2022

SOX9 induces and maintains neural stem cells

scientific journal article

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

scientific article published in October 2004

SRY, like HMG1, recognizes sharp angles in DNA ⬇️

scientific article published on December 1, 1992

Safety of medicines and the use of animals in research

scientific article published in The Lancet

Science and law. Integrity in international stem cell research collaborations

scientific article

Sex determination and SRY: down to a wink and a nudge?

scientific article

Sex determination and the control of Sox9 expression in mammals

scientific article published on 25 February 2011

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

scientific article

Sex reversal following deletion of a single distal enhancer of

scientific article

Sex-determining genes in mice: building pathways.

scientific article

Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation

scientific article

Sox genes find their feet ⬇️

scientific article published on June 1, 1997

Sox1 directly regulates the gamma -crystallin genes and is essential for lens development in mice ⬇️

scientific article published on March 15, 1998

Sox2 is required for sensory organ development in the mammalian inner ear

scientific journal article

Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens.

scientific article

Sry and sex determination: how lazy can it be?

scientific article published on 01 March 2002

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes

scientific article

Stem cell research policy and iPS cells

scientific article

Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism

scientific article published on 01 January 2020

Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells

scientific article

Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (WT1) gene

scientific article published on 03 June 2020

The <i>−KTS</i> splice variant of WT1 is essential for ovarian determination in mice

scientific article published on 02 November 2023

The Vascular Stem Cell Niche ⬇️

scientific article published on May 30, 2012

The early history of the Sox genes

scientific article published on 31 December 2009

The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroys ⬇️

scientific article published on October 25, 1991

The origin of the Mullerian duct in chick and mouse

scientific article published on 3 October 2006

The regulation of Sox9 expression in the gonad

scientific article published on 13 February 2019

The regulation of human embryo and stem-cell research in the United Kingdom

scientific article published in December 2008

What if stem cells turn into embryos in a dish?

scientific article published in September 2015

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene ⬇️

scientific article published on May 1, 1990

dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.

scientific article

iPS cells: mapping the policy issues

scientific article published on December 2009

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.

scientific article published on 15 February 2016

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

scientific article published on December 2012

Paulina is supported by:

About Paulina

Help