List of works - Robin Lovell-Badge

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

scientific article published on July 19, 1990

Multipotent cell lineages in early mouse development depend on SOX2 function

scientific journal article

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

scientific article

Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation

scientific article

Sox2 is required for sensory organ development in the mammalian inner ear

scientific journal article

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

scientific article published in October 2002

Sox genes find their feet

scientific article published on June 1, 1997

SRY, like HMG1, recognizes sharp angles in DNA

scientific article published on December 1, 1992

DNA Binding Activity of Recombinant SRY from Normal Males and XY Females

scientific article published on January 24, 1992

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

scientific article published in June 2006

dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.

scientific article

Generation of purified neural precursors from embryonic stem cells by lineage selection

scientific article published on August 27, 1998

A role for SOX1 in neural determination

scientific article published on May 1, 1998

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.

scientific article

Sox1 directly regulates the gamma -crystallin genes and is essential for lens development in mice

scientific article published on March 15, 1998

SOX3 is required during the formation of the hypothalamo-pituitary axis

scientific journal article

Genetic regulation of pituitary gland development in human and mouse

scientific article

Expression of Sry, the mouse sex determining gene

scientific article published on June 1, 1995

SOX9 induces and maintains neural stem cells

scientific journal article

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

scientific article published in October 2004

Sex determination and SRY: down to a wink and a nudge?

scientific article

Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans

scientific journal article

Oncogenicity of the developmental transcription factor Sox9.

scientific article

Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells

scientific article

Involvement of SOX proteins in lens-specific activation of crystallin genes

scientific article published on July 17, 1995

Identification of SOX3 as an XX male sex reversal gene in mice and humans

scientific article

Inverted repeat structure of the Sry locus in mice

scientific article published on September 1, 1992

Involvement ofSox1, 2and3in the early and subsequent molecular events of lens induction

scientific article published on July 1, 1998

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

scientific article published on December 2012

Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism

scientific article

Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination

scholarly article

Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis.

scientific article published on 9 January 2012

Imbalance between neutrophil elastase and its inhibitor α1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure

scientific article published on April 2013

Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand.

scientific article published on October 2013

SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development

scientific article

Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1

scientific article

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes

scientific article

Coordination of progenitor specification and growth in mouse and chick spinal cord

scientific article

CRISPR germline engineering--the community speaks

scientific article published on May 2015

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene

scientific article published on May 1, 1990

Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer

scientific article

Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia

scientific article

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.

scientific article published on 15 February 2016

Sex determination and the control of Sox9 expression in mammals

scientific article published on 25 February 2011

Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation

scientific article published on September 2011

Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue

scientific article published on 27 May 2009

The origin of the Mullerian duct in chick and mouse

scientific article published on 3 October 2006

The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroys

scientific article published on October 25, 1991

PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary

scientific article published on 24 October 2007

Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations

scientific article

List of works by Robin Lovell-Badge

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Multipotent cell lineages in early mouse development depend on SOX2 function

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation

Sox2 is required for sensory organ development in the mammalian inner ear

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

Sox genes find their feet

SRY, like HMG1, recognizes sharp angles in DNA

DNA Binding Activity of Recombinant SRY from Normal Males and XY Females

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.

Generation of purified neural precursors from embryonic stem cells by lineage selection

A role for SOX1 in neural determination

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.

Sox1 directly regulates the gamma -crystallin genes and is essential for lens development in mice

SOX3 is required during the formation of the hypothalamo-pituitary axis

Genetic regulation of pituitary gland development in human and mouse

Expression of Sry, the mouse sex determining gene

SOX9 induces and maintains neural stem cells

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

Sex determination and SRY: down to a wink and a nudge?

Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans

Oncogenicity of the developmental transcription factor Sox9.

Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells

Involvement of SOX proteins in lens-specific activation of crystallin genes

Identification of SOX3 as an XX male sex reversal gene in mice and humans

Inverted repeat structure of the Sry locus in mice

Involvement ofSox1, 2and3in the early and subsequent molecular events of lens induction

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism

Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination

Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis.

Imbalance between neutrophil elastase and its inhibitor α1-antitrypsin in obesity alters insulin sensitivity, inflammation, and energy expenditure

Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand.

SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development

Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes

Coordination of progenitor specification and growth in mouse and chick spinal cord

CRISPR germline engineering--the community speaks

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene

Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer

Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.

Sex determination and the control of Sox9 expression in mammals

Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation

Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue

The origin of the Mullerian duct in chick and mouse

The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroys

PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary

Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations