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List of works by Walter Fiers

A "universal" human influenza A vaccine

scientific article

A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody

scientific article published on 27 March 2015

A fairly conserved epitope on the hemagglutinin of influenza A (H3N2) virus with variable accessibility to neutralizing antibody

scientific article

A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus ⬇️

scientific article published on April 8, 2011

A universal influenza A vaccine based on the extracellular domain of the M2 protein

scientific article

An antibody which binds to the membrane-proximal end of influenza virus haemagglutinin (H3 subtype) inhibits the low-pH-induced conformational change and cell-cell fusion but does not neutralize virus ⬇️

scientific article published on July 1, 1998

An influenza A vaccine based on tetrameric ectodomain of matrix protein 2.

scientific article published on 5 February 2008

Antiserum against the conserved nine amino acid N-terminal peptide of influenza A virus matrix protein 2 is not immunoprotective ⬇️

scientific article published on October 21, 2010

Bacteriophage MS2 RNA: A correlation between the stability of the codon: Anticodon interaction and the choice of code words ⬇️

scientific article published on December 29, 1978

Bacteriophage MS2 RNA: Nucleotide Sequence of the End of the A Protein Gene and the Intercistronic Region ⬇️

scientific article published on January 24, 1973

Bioavailability of recombinant tumor necrosis factor determines its lethality in mice

scientific article published in October 2002

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

scientific article published on 28 February 2017

CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine.

scientific article

Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies

scientific article published in May 2002

Controlling influenza by cytotoxic T-cells: calling for help from destroyers

scientific article

Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody

scientific article

Cytokine research in Belgium ⬇️

scientific article published on 01 October 2011

Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies

scholarly article by Dirk De Valck published in December 1998

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity ⬇️

scientific article published on August 29, 1995

Evaluation of recombinant A/Victoria/3/75 (H3N2) influenza neuraminidase mutants as potential broad-spectrum subunit vaccines against influenza A.

scientific article published on January 1998

Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses

scientific article published on 19 August 2015

Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor ⬇️

scientific article published on August 4, 1995

Identification of caspases that cleave presenilin-1 and presenilin-2

scientific article (publication date: 19 February 1999)

Immunogenicity of live attenuated B. pertussis BPZE1 producing the universal influenza vaccine candidate M2e.

scientific article

Improved design and intranasal delivery of an M2e-based human influenza A vaccine

scientific article published on 12 June 2006

Improved periplasmic production of biologically active murine interleukin-2 in Escherichia coli through a single amino acid change at the cleavage site

scientific article published in 2006

In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides--evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei

scientific article

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly ⬇️

scientific article published on September 26, 2012

Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies

scientific article

M2-based influenza vaccines: recent advances and clinical potential

scientific article published on 22 September 2016

M2e-Based Universal Influenza A Vaccines

scientific article

M2e-based universal influenza A vaccine

scientific article

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

scientific article

M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza infection.

scientific article published on 15 March 2017

Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses ⬇️

scientific article published on June 1, 1998

Molecular and immunological characterization of soluble aggregated A/Victoria/3/75 (H3N2) influenza haemagglutinin expressed in insect cells

scientific article

Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF

scientific article published on 01 January 1999

Natural and long-lasting cellular immune responses against influenza in the M2e-immune host

scientific article

Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus

scientific article

Pandemic preparedness: toward a universal influenza vaccine

scientific article

Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae

scientific article published in May 1991

Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages

scientific article published on 14 May 2015

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

scientific article

Protection of Mice Against a Lethal Influenza Challenge by Immunization with Yeast‐Derived Recombinant Influenza Neuraminidase ⬇️

scientific article published on July 1, 1997

Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin

scientific article published in February 1999

Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen ⬇️

scientific article published on September 1, 1998

Recombinant Influenza Virus Carrying the Respiratory Syncytial Virus (RSV) F 85-93 CTL Epitope Reduces RSV Replication in Mice ⬇️

scientific article published on January 9, 2013

Recombinant neuraminidase vaccine protects against lethal influenza

scientific article published in April 1996

Recombinant secreted haemagglutinin protects mice against a lethal challenge of influenza virus

scientific article published in September 1993

Simian virus 40 mutants carrying extensive deletions in the 72-base-pair repeat region ⬇️

scientific article published on July 1, 1983

Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge

scientific article published on 14 May 2014

Soluble recombinant influenza vaccines ⬇️

scientific article published on December 29, 2001

Structural characterization of N-linked oligosaccharides from cellobiohydrolase I secreted by the filamentous fungus Trichoderma reesei RUTC 30.

scientific article

Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody

scientific article published on 21 January 2015

The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region

scientific article published on April 1998

The oxidative metabolism of glutamine. A modulator of reactive oxygen intermediate-mediated cytotoxicity of tumor necrosis factor in L929 fibrosarcoma cells

scientific article

The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection

scientific article

Tumor Necrosis Factor and Lymphotoxin

Tumor necrosis factor-alpha augmented tumor response in B16BL6 melanoma-bearing mice treated with stealth liposomal doxorubicin (Doxil) correlates with altered Doxil pharmacokinetics

scientific article published in April 2004

Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments.

scientific article

Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies

scientific article published in December 2008

Universal influenza A vaccine: optimization of M2-based constructs

scientific article published in June 2005

Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection.

scientific article published on 17 December 2010

pH-dependent aggregation and secretion of soluble monomeric influenza hemagglutinin ⬇️

scientific article published on January 1, 1998

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