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List of works by Linda Saif

A confirmation of sapovirus re-infection gastroenteritis cases with different genogroups and genetic shifts in the evolving sapovirus genotypes, 2002-2011 ⬇️

scientific article published on July 8, 2012

A human norovirus-like particle vaccine adjuvanted with ISCOM or mLT induces cytokine and antibody responses and protection to the homologous GII.4 human norovirus in a gnotobiotic pig disease model.

scientific article

Abiotic Stress and Phyllosphere Bacteria Influence the Survival of Human Norovirus and Its Surrogates on Preharvest Leafy Greens

scientific article published on 23 October 2015

Age-dependent variation in innate immune responses to porcine epidemic diarrhea virus infection in suckling versus weaned pigs

scientific article published on 26 September 2015

Altered pathogenesis of porcine respiratory coronavirus in pigs due to immunosuppressive effects of dexamethasone: implications for corticosteroid use in treatment of severe acute respiratory syndrome coronavirus

scientific article

An oral versus intranasal prime/boost regimen using attenuated human rotavirus or VP2 and VP6 virus-like particles with immunostimulating complexes influences protection and antibody-secreting cell responses to rotavirus in a neonatal gnotobiotic pi

scientific article

Antigenic relationships among porcine epidemic diarrhea virus and transmissible gastroenteritis virus strains

scientific article published on 14 January 2015

Antiviral effect of theaflavins against caliciviruses

scientific article

Association of enteric shedding of bovine torovirus (Breda virus) and other enteropathogens with diarrhea in veal calves ⬇️

scientific article published on April 1, 2003

Attempts to grow human noroviruses, a sapovirus, and a bovine norovirus in vitro.

scientific article published on 13 February 2018

Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1.

scholarly article

Binding of Human GII.4 Norovirus Virus-Like Particles to Carbohydrates of Romaine Lettuce Leaf Cell Wall Materials ⬇️

scientific article published on December 2, 2011

Biologic, antigenic, and full-length genomic characterization of a bovine-like coronavirus isolated from a giraffe

scientific article published on 7 March 2007

Bovine respiratory coronavirus

scientific article

Bovine torovirus (Breda virus) revisited

scientific article

Bovine-like coronaviruses isolated from four species of captive wild ruminants are homologous to bovine coronaviruses, based on complete genomic sequences.

scientific article published on 8 October 2008

Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility.

scientific article

Calves are susceptible to infection with the newly emerged porcine deltacoronavirus, but not with the swine enteric alphacoronavirus, porcine epidemic diarrhea virus

scientific article

Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway.

scientific article

Characterization and Prevalence of a New Porcine Calicivirus in Swine, United States ⬇️

scientific article published on June 1, 2011

Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A

scientific article

Characterization of emerging GII.g/GII.12 noroviruses from a gastroenteritis outbreak in the United States in 2010

scientific article

Comparative In Vitro and In Vivo Studies of Porcine Rotavirus G9P[13] and Human Rotavirus Wa G1P[8].

scientific article published on 14 October 2015

Comparative pathogenesis of US porcine epidemic diarrhea virus (PEDV) strain PC21A in conventional 9-day-old nursing piglets vs. 26-day-old weaned pigs

scientific article published on 30 April 2015

Comparison of ELISA and RT-PCR versus immune electron microscopy for detection of bovine torovirus (Breda virus) in calf fecal specimens

scientific article published on March 2003

Comparison of probiotic lactobacilli and bifidobacteria effects, immune responses and rotavirus vaccines and infection in different host species

scientific article published on 14 January 2016

Complete Genome Sequence of GII.4 Human Norovirus HS191 ⬇️

scientific article published on February 14, 2013

Complete genome sequence of the feline calicivirus 2280 strain from the american tissue culture collection

scientific article published on 20 June 2013

Complete genomic sequences, a key residue in the spike protein and deletions in nonstructural protein 3b of US strains of the virulent and attenuated coronaviruses, transmissible gastroenteritis virus and porcine respiratory coronavirus

scientific article published on 4 October 2006

Comprehensive review of human sapoviruses

scientific article

Coronaviruses

scientific article published on 29 March 2019

Cross-Species Virus Transmission and the Emergence of New Epidemic Diseases

scientific article

Cross-protection against a human enteric coronavirus and a virulent bovine enteric coronavirus in gnotobiotic calves

scientific article published on 13 September 2006

Cytokine responses in porcine respiratory coronavirus-infected pigs treated with corticosteroids as a model for severe acute respiratory syndrome

scientific article published on 20 February 2008

Decline of transmissible gastroenteritis virus and its complex evolutionary relationship with porcine respiratory coronavirus in the United States

Deletion of a 197-Amino-Acid Region in the N-Terminal Domain of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Piglets

scientific article published on 10 May 2017

Detection and Full-Length Genome Characterization of Novel Canine Vesiviruses

scientific article published on August 2015

Detection and characterization of bovine coronaviruses in fecal specimens of adult cattle with diarrhea during the warmer seasons

scientific article

Detection of Bovine Torovirus and other Enteric Pathogens in Feces from Diarrhea Cases in Cattle ⬇️

scientific article published on May 1, 2003

Detection of group 2a coronaviruses with emphasis on bovine and wild ruminant strains. Virus isolation and detection of antibody, antigen, and nucleic acid

scientific article published in January 2008

Detection of multiple human sapoviruses from imported frozen individual clams

scientific article published on 23 March 2013

Detection of respiratory and enteric shedding of bovine coronaviruses in cattle in an Ohio feedlot

scientific article published in July 2002

Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain

scientific article

Development of SYBR Green real-time RT-PCR for rapid detection, quantitation and diagnosis of unclassified bovine enteric calicivirus.

scientific article

Development of a new microwell hybridization assay and an internal control RNA for the detection of porcine noroviruses and sapoviruses by reverse transcription-PCR.

scientific article

Development of a one-step RT-PCR assay for detection of pancoronaviruses (α-, β-, γ-, and δ-coronaviruses) using newly designed degenerate primers for porcine and avian `fecal samples

scientific article published on 27 February 2018

Development of γδ T cell subset responses in gnotobiotic pigs infected with human rotaviruses and colonized with probiotic lactobacilli ⬇️

scientific article published on March 23, 2011

Discovery and Synthesis of Heterocyclic Carboxamide Derivatives as Potent Anti-norovirus Agents

scientific article published on January 2016

Discovery and genomic characterization of noroviruses from a gastroenteritis outbreak in domestic cats in the US

scientific article

Distinct characteristics and complex evolution of PEDV strains, North America, May 2013-February 2014.

scientific article

Divergent immunomodulating effects of probiotics on T cell responses to oral attenuated human rotavirus vaccine and virulent human rotavirus infection in a neonatal gnotobiotic piglet disease model

scientific article

Effects of dietary vitamin A content on antibody responses of feedlot calves inoculated intramuscularly with an inactivated bovine coronavirus vaccine

scientific article published on October 2013

Effects of different animal waste treatment technologies on detection and viability of porcine enteric viruses

scientific article published on 29 June 2007

Emerging and re-emerging coronaviruses in pigs

scientific article published in February 2019

Enteric and nasal shedding of bovine torovirus (Breda virus) in feedlot cattle

scientific article published in March 2002

Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection

scientific article

Experimental infection of gnotobiotic pigs with the cell-culture-adapted porcine deltacoronavirus strain OH-FD22.

scientific article published on 12 September 2016

Failure of propagation of human norovirus in intestinal epithelial cells with microvilli grown in three-dimensional cultures

scientific article published on 23 August 2013

Feline Calicivirus, Murine Norovirus, Porcine Sapovirus, and Tulane Virus Survival on Postharvest Lettuce

scientific article published on 22 May 2015

First Complete Genome Sequence of a Genogroup II Genotype 18 Porcine Norovirus, Strain QW125.

scientific article published on 13 June 2013

First Complete Genome Sequences of Genogroup VI Porcine Sapoviruses

scientific article published on 03 April 2014

First detection and molecular characterization of sapoviruses and noroviruses with zoonotic potential in swine in Ethiopia

scientific article published on 16 July 2016

Genetic Characterization and Classification of Human and Animal Sapoviruses

scientific article

Genetic diversity and recombination of porcine sapoviruses

scientific article

Genetic diversity of porcine sapoviruses.

scientific article published on 27 February 2007

Genetic recombination between two genotypes of genogroup III bovine noroviruses (BoNVs) and capsid sequence diversity among BoNVs and Nebraska-like bovine enteric caliciviruses

scientific article

Goblet cell depletion in small intestinal villous and crypt epithelium of conventional nursing and weaned pigs infected with porcine epidemic diarrhea virus

scientific article published on 24 October 2016

High titers of circulating maternal antibodies suppress effector and memory B-cell responses induced by an attenuated rotavirus priming and rotavirus-like particle-immunostimulating complex boosting vaccine regimen

scientific article

Human Respiratory Coronaviruses Detected In Patients with Influenza-Like Illness in Arkansas, USA

scientific article published on 26 March 2014

Human and animal enteric caliciviruses in oysters from different coastal regions of the United States

scientific article published on March 2006

Human rotavirus virus-like particle vaccines evaluated in a neonatal gnotobiotic pig model of human rotavirus disease ⬇️

scientific article published on February 1, 2013

IgY Antibodies Protect against Human Rotavirus Induced Diarrhea in the Neonatal Gnotobiotic Piglet Disease Model ⬇️

scientific article published on August 3, 2012

Immune responses to bovine norovirus-like particles with various adjuvants and analysis of protection in gnotobiotic calves.

scientific article

Immunohistochemical detection of the vomiting-inducing monoamine neurotransmitter serotonin and enterochromaffin cells in the intestines of conventional or gnotobiotic (Gn) pigs infected with porcine epidemic diarrhea virus (PEDV) and serum cytokine

scientific article published on 12 June 2018

Impact of nutrition and rotavirus infection on the infant gut microbiota in a humanized pig model.

scientific article

In vivo gut transcriptome responses to Lactobacillus rhamnosus GG and Lactobacillus acidophilus in neonatal gnotobiotic piglets

scientific article

Inactivated rotavirus vaccine induces protective immunity in gnotobiotic piglets

scientific article published on 15 June 2010

Induction of mucosal immune responses and protection against enteric viruses: rotavirus infection of gnotobiotic pigs as a model.

scientific article

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease

scientific article

Innate immune responses to human rotavirus in the neonatal gnotobiotic piglet disease model

scientific article published on 01 October 2010

Integrating bacterial and viral water quality assessment to predict swimming-associated illness at a freshwater beach: a cohort study

scientific article

Internalization of Sapovirus, a Surrogate for Norovirus, in Romaine Lettuce and the Effect of Lettuce Latex on Virus Infectivity ⬇️

scientific article published on June 29, 2012

Isolation and characterization of porcine deltacoronavirus from pigs with diarrhea in the United States

scientific article published on 4 March 2015

Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs.

scientific article

Lactobacilli and Bifidobacteria enhance mucosal B cell responses and differentially modulate systemic antibody responses to an oral human rotavirus vaccine in a neonatal gnotobiotic pig disease model

scientific article

Lactobacilli and bifidobacteria promote immune homeostasis by modulating innate immune responses to human rotavirus in neonatal gnotobiotic pigs

scientific article

Lactogenic immunity and vaccines for porcine epidemic diarrhea virus (PEDV): Historical and current concepts

scientific article

Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice

scientific article

Low titer maternal antibodies can both enhance and suppress B cell responses to a combined live attenuated human rotavirus and VLP-ISCOM vaccine

scientific article published in December 2005

Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection

scientific article published on January 2004

Mechanism of Cell Culture Adaptation of an Enteric Calicivirus, the Porcine Sapovirus Cowden Strain ⬇️

scientific article

Molecular analysis of the S1 subunit of the spike glycoprotein of respiratory and enteric bovine coronavirus isolates

scientific article published in March 2002

Molecular characterization of a new species in the genus Alphacoronavirus associated with mink epizootic catarrhal gastroenteritis

scientific article

Molecular characterization of novel G5 bovine rotavirus strains.

scientific article

Molecular characterization of the major capsid protein VP6 of bovine group B rotavirus and its use in seroepidemiology

scientific article published on September 2005

Molecular detection and genetic characterization of kobuviruses and astroviruses in asymptomatic local pigs in East Africa

scientific article published on 11 December 2013

Mucosal and systemic antibody responses and protection induced by a prime/boost rotavirus-DNA vaccine in a gnotobiotic pig model

scientific article published on 09 April 2005

Multiplex real-time RT-PCR for the simultaneous detection and quantification of GI, GII and GIV noroviruses.

scientific article

Nitric oxide is elicited and inhibits viral replication in pigs infected with porcine respiratory coronavirus but not porcine reproductive and respiratory syndrome virus

scientific article

Occurrence of human enteric viruses at freshwater beaches during swimming season and its link to water inflow

scientific article published on 10 December 2013

Pathogenesis of GIII.2 bovine norovirus, CV186-OH/00/US strain in gnotobiotic calves

scientific article

Pathogenesis of a genogroup II human norovirus in gnotobiotic pigs

scientific article

Pathogenicity of 2 porcine deltacoronavirus strains in gnotobiotic pigs

scientific article published on April 2015

Porcine Rotaviruses: Epidemiology, Immune Responses and Control Strategies

scientific article

Porcine deltacoronavirus induces apoptosis in swine testicular and LLC porcine kidney cell lines in vitro but not in infected intestinal enterocytes in vivo

scientific article published on 30 October 2015

Porcine deltacoronavirus infection: Etiology, cell culture for virus isolation and propagation, molecular epidemiology and pathogenesis

scientific article

Porcine enteric caliciviruses: genetic and antigenic relatedness to human caliciviruses, diagnosis and epidemiology

scientific article published on 29 December 2006

Porcine epidemic diarrhea virus infection: Etiology, epidemiology, pathogenesis and immunoprophylaxis

scientific article published on 26 February 2015

Porcine lung mesenchymal stromal cells possess differentiation and immunoregulatory properties

scientific article

Porcine noroviruses related to human noroviruses

scientific article

Porcine reproductive and respiratory syndrome virus modifies innate immunity and alters disease outcome in pigs subsequently infected with porcine respiratory coronavirus: implications for respiratory viral co-infections

scientific article published on 5 August 2009

Porcine reproductive and respiratory syndrome virus-induced immunosuppression exacerbates the inflammatory response to porcine respiratory coronavirus in pigs

scientific article

Postharvest Survival of Porcine Sapovirus, a Human Norovirus Surrogate, on Phytopathogen-Infected Leafy Greens

scientific article published on August 2015

Prenatal vitamin A deficiency impairs adaptive immune responses to pentavalent rotavirus vaccine (RotaTeq®) in a neonatal gnotobiotic pig model

scientific article published on 29 December 2013

Prenatally acquired vitamin A deficiency alters innate immune responses to human rotavirus in a gnotobiotic pig model

scientific article published on 27 March 2013

Prevalence and molecular characterization of human noroviruses and sapoviruses in Ethiopia

scientific article published on 19 May 2016

Prevalence and molecular characterization of porcine enteric caliciviruses and first detection of porcine kobuviruses in US swine

scientific article

Prevalence of noroviruses and sapoviruses in swine of various ages determined by reverse transcription-PCR and microwell hybridization assays

scientific article

Prevalence of porcine noroviruses, molecular characterization of emerging porcine sapoviruses from finisher swine in the United States, and unified classification scheme for sapoviruses

scientific article published on 15 May 2013

Probiotic Lactobacillus acidophilus enhances the immunogenicity of an oral rotavirus vaccine in gnotobiotic pigs

scientific article published on 19 May 2008

Probiotics and colostrum/milk differentially affect neonatal humoral immune responses to oral rotavirus vaccine

scientific article published on 21 February 2013

Production of hybrid double- or triple-layered virus-like particles of group A and C rotaviruses using a baculovirus expression system

scientific article published on October 2002

Quasispecies of bovine enteric and respiratory coronaviruses based on complete genome sequences and genetic changes after tissue culture adaptation

scientific article published on 16 April 2007

Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea.

scientific article published on 22 April 2011

Recognition of Histo-Blood Group Antigen-Like Carbohydrates in Lettuce by Human GII.4 Norovirus

scientific article published on 11 March 2016

Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments

scientific article published on 5 July 2008

Retrospective serosurveillance of bovine norovirus (GIII.2) and nebovirus in cattle from selected feedlots and a veal calf farm in 1999 to 2001 in the United States

scientific article published on 25 July 2013

Reverse genetics system for porcine enteric calicivirus, a prototype sapovirus in the Caliciviridae

scientific article

Sequence analysis of unusual P[7]G5 bovine rotavirus strains reveals evidence of interspecies transmission

scientific article published on 26 August 2009

Skin Vaccination against Rotavirus Using Microneedles: Proof of Concept in Gnotobiotic Piglets

scientific article

Stability of and Attachment to Lettuce by a Culturable Porcine Sapovirus Surrogate for Human Caliciviruses ⬇️

scientific article published on March 23, 2012

Stability of bovine coronavirus on lettuce surfaces under household refrigeration conditions ⬇️

scientific article published on December 13, 2011

Stage of Gestation at Porcine Epidemic Diarrhea Virus Infection of Pregnant Swine Impacts Maternal Immunity and Lactogenic Immune Protection of Neonatal Suckling Piglets ⬇️

Strategies for design and application of enteric viral vaccines

scientific article

Structural alteration of tight and adherens junctions in villous and crypt epithelium of the small and large intestine of conventional nursing piglets infected with porcine epidemic diarrhea virus

scientific article published on 30 March 2015

Susceptibility of porcine IPEC-J2 intestinal epithelial cells to infection with porcine deltacoronavirus (PDCoV) and serum cytokine responses of gnotobiotic pigs to acute infection with IPEC-J2 cell culture-passaged PDCoV

article

Systemic and intestinal antibody responses to NSP4 enterotoxin of Wa human rotavirus in a gnotobiotic pig model of human rotavirus disease

scientific article published on September 2002

Systemic and intestinal antibody secreting cell responses and protection in gnotobiotic pigs immunized orally with attenuated Wa human rotavirus and Wa 2/6-rotavirus-like-particles associated with immunostimulating complexes

scientific article published in March 2002

The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.

scientific article

The global one health paradigm: challenges and opportunities for tackling infectious diseases at the human, animal, and environment interface in low-resource settings

scientific article

The pig: a model for human infectious diseases

scientific article published on 05 December 2011

Tissue Distribution and Visualization of Internalized Human Norovirus in Leafy Greens.

scientific article

Tissue-specific mRNA expression profiles of porcine Toll-like receptors at different ages in germ-free and conventional pigs

scientific article

Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs.

scientific article published on 31 October 2008

Transfer of maternal cytokines to suckling piglets: in vivo and in vitro models with implications for immunomodulation of neonatal immunity.

scientific article

Transmission of bovine coronavirus and serologic responses in feedlot calves under field conditions

article

Two-way antigenic cross-reactivity between severe acute respiratory syndrome coronavirus (SARS-CoV) and group 1 animal CoVs is mediated through an antigenic site in the N-terminal region of the SARS-CoV nucleoprotein

scientific article

Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)

scientific article

Unraveling the Differences between Gram-Positive and Gram-Negative Probiotics in Modulating Protective Immunity to Enteric Infections.

scientific article published on 27 March 2017

Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs.

scientific article published on 18 April 2008

Vitamin A deficiency impairs adaptive B and T cell responses to a prototype monovalent attenuated human rotavirus vaccine and virulent human rotavirus challenge in a gnotobiotic piglet model

scientific article

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