List of works by Pamela J. Bjorkman

<i>In vitro</i> characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2

scientific article published on 10 March 2021

A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates

scholarly article by Jennifer R Keeffe et al published 6 November 2018 in Cell Reports

A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies

scientific article

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

scientific article published on 30 October 2015

A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

scholarly article published by Pradeep D Uchil in 2019

A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch

scientific article published on 21 October 2020

A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques

scientific article published on 24 March 2020

A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity

scientific article

A freeze substitution fixation-based gold enlarging technique for EM studies of endocytosed Nanogold-labeled molecules

scientific article

A gut-derived metabolite alters brain activity and anxiety behaviour in mice

scientific article

A linear lattice model for polyglutamine in CAG-expansion diseases

scientific article

A mouse model for HIV-1 entry

scientific article

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein

scientific article published on 03 March 2020

Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.

scientific article published on 3 June 2015

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

scientific article

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

scientific article

Antibody engineering for increased potency, breadth and half-life

scientific article published on May 2015

Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody

scientific article published on 02 December 2019

Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.

scientific article

Biophysical and Biochemical Characterization of Avian Secretory Component Provides Structural Insights into the Evolution of the Polymeric Ig Receptor

scientific article published on 13 July 2016

Bivalent binding of IgA1 to FcalphaRI suggests a mechanism for cytokine activation of IgA phagocytosis

scientific article published in March 2003

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

scientific article published on 21 May 2019

Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.

scientific article

Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection

scholarly article published by Pamela J. Bjorkman in 2018

CATNAP: a tool to compile, analyze and tally neutralizing antibody panels

scientific article published on 4 June 2015

Can we use structural knowledge to design a protective vaccine against HIV-1?

scientific article published on 27 November 2019

Characterization of Antibody Bipolar Bridging Mediated by the Human Cytomegalovirus Fc Receptor gp68

scientific article (publication date: 6 January 2016)

Climate change and the integrity of science

scientific article

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

scientific article

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

scientific article published in Nature

Comparative analysis of anti-polyglutamine Fab crystals grown on Earth and in microgravity

scientific article published on 22 September 2016

Comparison of FcRn- and pIgR-mediated transport in MDCK cells by fluorescence confocal microscopy

scientific article

Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

scientific article published on 16 August 2017

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

scientific article

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues

scientific article

Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

scientific article published on 08 June 2022

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals

scientific article published on 16 May 2020

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

scientific article published on 18 June 2020

Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop

scientific article published on 31 October 2016

Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

scientific article published on 29 March 2021

Cryo-electron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L1.

scientific article

Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor

scientific article

Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.

scientific article

Crystal structure of TNFα complexed with a poxvirus MHC-related TNF binding protein

scientific article

Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8Å ⬇️

scientific article published on October 28, 2010

Crystal structure of a polymeric immunoglobulin binding fragment of the human polymeric immunoglobulin receptor

scientific article published in November 2004

Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains

scientific article published on 12 April 2005

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

scientific article

Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging

scientific article published on 2 May 2006

Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein

scientific article published in November 2004

DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions

article

De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2

scientific article published on 05 November 2020

Design and characterization of structured protein linkers with differing flexibilities

scientific article

Design and expression of a dimeric form of human immunodeficiency virus type 1 antibody 2G12 with increased neutralization potency

scientific article published on 22 October 2008

Designed oligomers of cyanovirin-N show enhanced HIV neutralization

scientific article

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York

scientific article published on 09 August 2021

Dimeric 2G12 as a potent protection against HIV-1.

scientific article

Electron tomography of HIV-1 infection in gut-associated lymphoid tissue

scientific article

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine

scientific article

Electron tomography visualization of HIV-1 fusion with target cells using inhibitors to trap the prehairpin intermediate ⬇️

scientific article published on 22 July 2020

Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

scientific article published on 01 March 2019

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

scientific article

Erratum: T-cell antigen receptor genes and T-cell recognition

scientific article published in Nature

Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents

scientific article

Evolution of Antibody Immunity to SARS-CoV-2

scientific article published on 05 November 2020

Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10.

scholarly article

Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor

scientific article

Fc receptors and their interactions with immunoglobulins

scientific article

FcRn mediates elongated serum half-life of human IgG in cattle

scientific article published on 15 February 2006

Few and far between: how HIV may be evading antibody avidity

scientific article published in May 2010

Finding the groove

scientific article published on August 2006

Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses

scientific article published on 06 April 2023

Gut microbiota utilize immunoglobulin A for mucosal colonization

scientific article published in Science

HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design

scientific article published on 01 November 2018

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

scientific article published on 24 October 2012

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

scientific article

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

scientific article published on 16 September 2013

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

scientific article

Harnessing Avidity: Quantifying the Entropic and Energetic Effects of Linker Length and Rigidity for Multivalent Binding of Antibodies to HIV-1

scientific article published on 23 October 2019

Heterotypic interactions between transferrin receptor and transferrin receptor 2.

scientific article

How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika

scientific article published in 2021

IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand-induced redistribution

scientific article published on November 2002

IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand-induced redistribution

scientific article published on February 2002

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

scientific article published on 29 May 2019

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

scientific article

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

scientific article

Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc

scientific article (publication date: 5 June 2003)

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

scientific article published on 15 August 2005

Intra-spike crosslinking overcomes antibody evasion by HIV-1

scientific article

Investigate the origins of COVID-19

scientific article

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells

scientific article

Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor

scientific article

Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography

scientific article published on 15 February 2017

Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype

scientific article published on 14 August 2020

Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype

scientific article published on 17 November 2020

MHC homologs in the nervous system--they haven't lost their groove

scientific article

Mechanisms of virus dissemination in bone marrow of HIV-1-infected humanized BLT mice

scientific article published on 28 October 2019

Modeling Entropic and Energetic Effects of Linker Length and Rigidity within Synthetic HIV-1 Antibodies designed to Bind Bivalently to Env Spikes

article

Molecular Competition for NKG2D

article

Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2 and zoonotic coronaviruses

scientific article published on 17 November 2020

Multiscale imaging of HIV-1 transmission in humanized mice

scientific article published on 7 September 2017

Nanogold as a specific marker for electron cryotomography

scientific article

Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells

scientific article published on 20 July 2020

Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

scientific article

Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains

scientific article

Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane

scientific article

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

scientific article published on 21 April 2015

Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer

scientific article published on 08 February 2022

Not just Salk

scientific article published in September 2017

Not second class: the first class II MHC crystal structure

scientific article published in January 2015

Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion

article

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

scientific article

Peptidoglycan Production by an Insect-Bacterial Mosaic

scientific article published on 03 October 2019

Phenotypic properties of transmitted founder HIV-1

scientific article

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody

scientific article published on 01 January 2020

Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody

scientific article published on 01 February 2020

Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico

scientific article

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

scientific article

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

scientific article published on 30 January 2020

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

scientific article

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

scientific article published on 12 October 2020

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

scientific article

Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env

scientific article published on 24 November 2021

Single-chain Fv-based anti-HIV proteins: potential and limitations

scientific article

Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae

scientific article

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

scientific article

Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12

scientific article

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

scientific article

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody

scientific article

Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody

scientific article published on 22 April 2020

Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

scientific article

Structural basis for germline antibody recognition of HIV-1 immunogens

scientific article published on 21 March 2016

Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa

scientific article published on 2 February 2016

Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.

scientific article published on 28 March 2018

Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies

scientific article published on 30 August 2020

Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY.

scientific article

Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor

scientific article

Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity

scientific article

Structure of a pheromone receptor-associated MHC molecule with an open and empty groove

scientific article

Structure of an HIV-2 gp120 in Complex with CD4.

scientific article published on 25 November 2015

Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies

scientific article published on 24 June 2020

Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

scientific article published on 29 May 2020

The Crystal Structure of CHIR-AB1: A Primordial Avian Classical Fc Receptor

scientific article

The chicken yolk sac IgY receptor, a functional equivalent of the mammalian MHC-related Fc receptor, is a phospholipase A2 receptor homolog

scientific article

The chicken yolk sac IgY receptor, a mammalian mannose receptor family member, transcytoses IgY across polarized epithelial cells

scientific article published on 6 February 2008

The herpes virus Fc receptor gE-gI mediates antibody bipolar bridging to clear viral antigens from the cell surface

scientific article

The human cytomegalovirus Fc receptor gp68 binds the Fc CH2-CH3 interface of immunoglobulin G

scientific article

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins

scientific article

The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model

scientific article

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

scientific article published on March 2008

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

scientific article published on 21 September 2015

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping

scientific article published on 22 October 2015

X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer

scientific article published on 29 September 2017

Zn-alpha2-glycoprotein, an MHC class I-related glycoprotein regulator of adipose tissues: modification or abrogation of ligand binding by site-directed mutagenesis

scientific article published in February 2006

pH dependence and stoichiometry of binding to the Fc region of IgG by the herpes simplex virus Fc receptor gE-gI.

scientific article published on 20 January 2004

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