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List of works by Antti Pertovaara

5-HT1A receptors in endogenous regulation of neuropathic hypersensitivity in the rat

scientific article published on 06 March 2006

A Neuronal Correlate of Secondary Hyperalgesia in the Rat Spinal Dorsal Horn Is Submodality Selective and Facilitated by Supraspinal Influence ⬇️

scientific article published on January 1, 1998

A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone

scientific article published in September 1998

A dissociative change in the efficacy of supraspinal versus spinal morphine in the neuropathic rat.

scientific article published in February 2003

A noninvasive method for studying quantitatively heat-evoked nocifensive hindlimb withdrawal reflexes in lightly anesthetized rats

scientific article published on 01 February 1996

A potential aphrodisiac for female macaques

scientific article published in September 2004

A role of supraspinal galanin in behavioural hyperalgesia in the rat.

scientific article

A segregated neural pathway for prefrontal top-down control of tactile discrimination

scientific article

Adrenergic Receptors

article from 2009

Allodynia induced by regenerating axons is not positively correlated with degree of autotomy in the rat

scientific article published on 01 December 1999

Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia

scientific article

Altered control of submaximal bite force during bruxism in humans

scientific article published on 01 March 1999

Altered skin sensitivity in chronic itch: role of peripheral and central mechanisms ⬇️

scientific article published on June 13, 1997

Amygdaloid administration of tetrapentylammonium attenuates development of pain and anxiety-like behavior following peripheral nerve injury

article

An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist

scientific article published on 01 November 1995

Antinociception by motor cortex stimulation in the neuropathic rat: does the locus coeruleus play a role?

scientific article published on 14 October 2009

Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies.

scientific article published on June 1993

Anxiety- and activity-related effects of paracetamol on healthy and neuropathic rats

scientific article published in February 2018

Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia

scientific article

Attempted reversal of cocaine-induced antinociceptive effects with naloxone, an opioid antagonist ⬇️

scientific article published on January 17, 1991

Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals

scientific article

Behavioural measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy

scientific article published in March 1999

Bidirectional amygdaloid control of neuropathic hypersensitivity mediated by descending serotonergic pathways acting on spinal 5-HT3 and 5-HT1A receptors

scientific article

Blood flow increase in the orofacial area of humans induced by painful stimulation.

scientific article published on January 1994

Changes in tooth pulpal detection and pain thresholds in relation to jaw movement in man

scientific article published on 01 January 2001

Chapter 13 Descending inhibitory systems

scientific article published on 01 January 2006

Chronic spinal nerve ligation induces changes in response characteristics of nociceptive spinal dorsal horn neurons and in their descending regulation originating in the periaqueductal gray in the rat.

scientific article published in October 1997

Colorectal distension-induced suppression of a nociceptive somatic reflex response in the rat: modulation by tissue injury or inflammation

scientific article

Comparison of the visceral antinociceptive effects of spinally administered MPV-2426 (fadolmidine) and clonidine in the rat.

scientific article

Correlation of human cold pressor pain responses with 5-HT1A receptor binding in the brain

article

Corticotropin-releasing factor in the rat amygdala differentially influences sensory-discriminative and emotional-like pain response in peripheral neuropathy

scientific article published on 10 July 2010

Cutaneous vascular responses evoked by noxious stimulation in rats with the spinal nerve ligation-induced model of neuropathy

scientific article

Dental analgesia produced by non-painful low-frequency stimulation is not influenced by stress or reversed by naloxone

scientific article published on 01 August 1982

Descending antinociception induced by secondary somatosensory cortex stimulation in experimental neuropathy: role of the medullospinal serotonergic pathway

scientific article published on 4 January 2017

Descending effect on spinal nociception by amygdaloid glutamate varies with the submodality of noxious test stimulation

scientific article published on 18 April 2014

Descending modulation of neuropathic hypersensitivity by dopamine D2 receptors in or adjacent to the hypothalamic A11 cell group.

scientific article published on 14 January 2009

Dexamethasone attenuates exercise-induced dental analgesia in man.

scientific article published in June 1990

Different roles of alpha 2-adrenoceptors of the medulla versus the spinal cord in modulation of mustard oil-induced central hyperalgesia in rats.

scientific article published in February 1996

Differential associations between brain 5-HT(1A) receptor binding and response to pain versus touch.

scientific article

Differential effects of left/right neuropathy on rats' anxiety and cognitive behavior

scientific article published on 24 August 2012

Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy

scientific article published on 31 December 2012

Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity

scientific article published in September 2002

Dose-related effects of memantine on a mismatch negativity-like response in anesthetized rats.

scientific article published on 15 March 2010

Dual influence of the striatum on neuropathic hypersensitivity

scientific article published on 17 September 2007

Effect of subcutaneous formalin treatment on responses to bulboreticular nociceptive neurons in the rat

article

Effective treatment of osteoarthritic pain, tackling the challenge with pets

scientific article published on 01 April 2012

Effects of Intramuscular Heating-needle Stimulation in Controlling Adjuvant-induced Muscle Nociception in Rats: Differential Roles of Thalamic Purinergic P2X3 Receptors

scientific article published on 06 March 2020

Effects of an NMDA-receptor antagonist MK-801 on an MMN-like response recorded in anesthetized rats

scientific article published on 13 February 2008

Effects of different sensory and behavioral manipulations on autotomy caused by a sciatic lesion in rats

scientific article published in January 1991

Effects of jaw clenching, jaw movement and static jaw position on facial skin sensitivity to non-painful electrical stimulation in man.

scientific article

Effects of medetomidine, an alpha-2 adrenoceptor agonist, and atipamezole, an alpha-2 antagonist, on spatial memory performance in adult and aged rats

scientific article published on September 1, 1992

Effects of simulated weightlessness on intramuscular hypertonic saline induced muscle nociception and spinal Fos expression in rats

scientific article published on 15 November 2014

Efficacy of kilohertz-frequency and conventional spinal cord stimulation in rat models of different pain conditions.

scientific article

Enhanced pronociception by amygdaloid group I metabotropic glutamate receptors in nerve-injured animals

scientific article

Exploration of supraspinal mechanisms in effects of spinal cord stimulation: role of the locus coeruleus

scientific article published on 11 September 2013

Facilitation of tactile working memory by top-down suppression from prefrontal to primary somatosensory cortex during sensory interference

scientific article published on 15 February 2011

Faculty of 1000 evaluation for Optoactivation of locus ceruleus neurons evokes bidirectional changes in thermal nociception in rats

Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways

scientific article published on 13 November 2015

Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity

scientific article published on 7 October 2014

Increasing top-down suppression from prefrontal cortex facilitates tactile working memory.

scientific article published on 28 July 2009

Influence of Preemptive Treatment with MK-801, an N-methyl-D-aspartate Receptor Antagonist, on Development of Neuropathic Symptoms Induced by Spinal Nerve Ligation in the Rat

article

Influence of amygdaloid glutamatergic receptors on sensory and emotional pain-related behavior in the neuropathic rat.

scientific article published on 25 January 2010

Influence of an Experimental Peripheral Mononeuropathy on the Responses of Medial Bulboreticular Neurons to Noxious Skin Stimulation and the Modulation of the Responses by an α2-Adrenoceptor Agonist in the Rat

article

Influence of arthritis on descending modulation of nociception from the paraventricular nucleus of the hypothalamus

scientific article

Influence of peripheral nerve injury on response properties of locus coeruleus neurons and coeruleospinal antinociception in the rat.

scientific article

Influence of spinalization on spinal withdrawal reflex responses varies depending on the submodality of the test stimulus and the experimental pathophysiological condition in the rat.

scientific article published in June 1998

Influence of the dopamine D2 receptor knockout on pain-related behavior in the mouse

scientific article published in August 2005

Influence of various experimental parameters on the incidence of thermal and mechanical hyperalgesia induced by a constriction mononeuropathy of the sciatic nerve in lightly anesthetized rats.

scientific article published in July 1994

Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy

scientific journal article

Inhibitors of catechol-O-methyltransferase sensitize mice to pain

scientific article published on December 2010

Intrathecal administration of a gap junction decoupler, an inhibitor of Na(+)-K(+)-2Cl(-) cotransporter 1, or a GABA(A) receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat.

scientific article published on 16 September 2010

Intrathecal administration of antioxidants attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat

scientific article published on 01 April 2011

Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in the medetomidine-induced antinociception

scientific article published in January 1991

Is finding the common biological link(s) between pain and affect an infinity quest?

scientific article published on 01 July 2018

It’s not cool to reduce the skin temperature and activate the TRPM8 ion channel after spinal injury

scientific article published on 01 January 2013

Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats

scientific article

Localization of touch versus heat pain in the human hand: a dissociative effect of temporal parameters on discriminative capacity and decision strategy

scientific article published on 9 February 2006

Masseter inhibitory reflex in humans: attempted modulation by various experimental parameters

scientific article published in October 1999

Mechanical antihypersensitivity effect induced by repeated spinal administrations of a TRPA1 antagonist or a gap junction decoupler in peripheral neuropathy

scientific article published on 24 September 2016

Mechanisms of cognitive impairment in chronic pain patients can now be studied preclinically by inducing cognitive deficits with an experimental animal model of chronic neuropathic pain

scientific article published on 01 December 2015

Medetomidine, atipamezole, and guanfacine in delayed response performance of aged monkeys

scientific article published on 01 November 1996

Metabotropic glutamate 5 receptor in the infralimbic cortex contributes to descending pain facilitation in healthy and arthritic animals

scientific article

Modulation of facial sensitivity by navigated rTMS in healthy subjects

scientific article published on 6 February 2009

Modulation of pain by [1DMe]NPYF, a stable analogue of neuropeptide FF, in neuropathic rats.

scientific article

Navigated transcranial magnetic stimulation of the primary somatosensory cortex impairs perceptual processing of tactile temporal discrimination

scientific article published on 8 April 2008

Neural Substrate for Metacognitive Accuracy of Tactile Working Memory

scientific article

Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat.

scientific article published on 20 May 2008

Neurotransmitters behind pain relief with transcranial magnetic stimulation - positron emission tomography evidence for release of endogenous opioids

scientific article published on 11 May 2017

Noradrenergic pain modulation

scientific article published on 9 October 2006

Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties

scientific article published in February 2001

Pain treatment with intrathecal corticosteroids: Much ado about nothing? But epidural corticosteroids for radicular pain is still an option

Pain-related behavior following REM sleep deprivation in the rat: influence of peripheral nerve injury, spinal glutamatergic receptors and nitric oxide

scientific article published on 24 February 2007

Peripheral suppression of arthritic pain by intraarticular fadolmidine, an alpha 2-adrenoceptor agonist, in the rat.

scientific article published in July 2007

Peripherally Administered alpha2-Adrenoceptor Agonist in the Modulation of Chronic Allodynia Induced by Spinal Nerve Ligation in the Rat

scientific article published on 01 November 1997

Potential role of spinal TRPA1 channels in antinociceptive tolerance to spinally administered morphine

scientific article published on 14 December 2015

Prolactin-releasing peptide affects pain, allodynia and autonomic reflexes through medullary mechanisms

scientific article published in March 2004

Pronociception from the dorsomedial nucleus of the hypothalamus is mediated by the rostral ventromedial medulla in healthy controls but is absent in arthritic animals

scientific article published on 9 October 2013

Pronociceptive changes in response properties of rostroventromedial medullary neurons in a rat model of peripheral neuropathy

scientific article published on 24 September 2007

Pronociceptive effects induced by cutaneous application of a transient receptor potential ankyrin 1 (TRPA1) channel agonist methylglyoxal in diabetic animals: comparison with tunicamycin-induced endoplastic reticulum stress

scientific article published in August 2016

Psychiatric (axis I) and personality (axis II) disorders in patients with burning mouth syndrome or atypical facial pain

scientific article published on 01 October 2011

RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.

scientific article published in January 2005

Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits ⬇️

scientific article published on April 11, 2012

Regulation of neuropathic hypersensitivity by α(2) -adrenoceptors in the pontine A7 cell group

scientific article published on 25 September 2012

Regulation of neuropathic pain behavior by amygdaloid TRPC4/C5 channels

scientific article published on 29 September 2015

Response properties of nociceptive neurons in the caudal ventrolateral medulla (CVLM) in monoarthritic and healthy control rats: modulation of responses by the paraventricular nucleus of the hypothalamus (PVN).

scientific article

Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone

scientific article

Right secondary somatosensory cortex-a promising novel target for the treatment of drug-resistant neuropathic orofacial pain with repetitive transcranial magnetic stimulation

scientific article published in July 2015

Role of spinal 5-HT receptors in cutaneous hypersensitivity induced by REM sleep deprivation

scientific article published in June 2008

Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat.

scientific article

Roles of the rostroventromedial medulla and the spinal 5-HT(1A) receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat.

scientific article published on 14 April 2010

Selective and segmentally restricted antinociception induced by MPV-2426, a novel alpha-2-adrenoceptor agonist, following intrathecal administration in the rat

scientific article published on 01 October 2000

Sinomenine against neuropathic pain hypersensitivity

scientific article published on 01 October 2014

Somatotopic blocking of sensation with navigated transcranial magnetic stimulation of the primary somatosensory cortex

scientific article published in October 2005

Spatial discrimination of one versus two test stimuli in the human skin: dissociation of mechanisms depending on the task and the modality of stimulation

scientific article published on 01 August 2002

Spatial features of vibrotactile masking effects on airpuff-elicited sensations in the human hand

scientific article published in January 1990

Spatial integration of cold pressor pain sensation in humans

scientific article published on 01 May 2004

Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat.

scientific article published on 17 August 2013

Spinal TRPA1 ion channels contribute to cutaneous neurogenic inflammation in the rat.

scientific article

Spinal and pontine alpha2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat.

scientific article published on 8 September 2006

Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy

scientific article published on 23 December 2015

Spinal nerve ligation-induced neuropathy in the rat: sensory disorders and correlation between histology of the peripheral nerves

scientific article published on 01 March 1999

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat.

scientific article published on 5 January 2011

Spinal versus brain microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain

scientific article

Striatal dopamine D2 receptors attenuate neuropathic hypersensitivity in the rat.

scientific article

Striatal dopamine D2 receptors in modulation of pain in humans: a review

scientific article published in October 2004

Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain

scientific article published in September 2004

Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects

scientific article

Submodality-selective hyperalgesia adjacent to partially injured sciatic nerve in the rat is dependent on capsaicin-sensitive afferent fibers and independent of collateral sprouting or a dorsal root reflex

scientific article published in January 1997

Suppression of pain behavior in nerve-injured rats by an anti-inflammatory drug: Promises and caveats for translation to clinical applications in man

scientific article published on 01 October 2010

Supraspinal influence on hindlimb withdrawal thresholds and mustard oil-induced secondary allodynia in rats

scientific article published in January 1997

TRPA1 Antagonists for Pain Relief

scientific article published on 01 November 2018

TRPA1 ion channel in the spinal dorsal horn as a therapeutic target in central pain hypersensitivity and cutaneous neurogenic inflammation

scientific article published on 27 May 2011

TRPA1: a transducer and amplifier of pain and inflammation

scientific article

The Effect of a Selective α2-Adrenoceptor Antagonist on Pain Behavior of the Rat Varies, Depending on Experimental Parameters

scientific article published on 01 February 1998

The Effects of Stimulus Area and Adaptation Temperature on Warm and Heat Pain Thresholds in Man

article

The alpha2A-adrenoceptor subtype is not involved in inflammatory hyperalgesia or morphine-induced antinociception

scientific article published in May 2003

The analgesic effect of therapeutic rTMS is not mediated or predicted by comorbid psychiatric or sleep disorders

scientific article published on November 2016

The dissociation of sedative from spinal antinociceptive effects following administration of a novel alpha-2-adrenoceptor agonist, MPV-2426, in the locus coeruleus in the rat

scientific article published on 01 July 2000

The effect of interstimulus interval on somatosensory point localization

scientific article published on 01 March 2004

The impact of age on emotional and cognitive behaviours triggered by experimental neuropathy in rats

scientific article published on 26 April 2009

The influence of exercise on dental pain thresholds and the release of stress hormones

scientific article published on 01 December 1984

The noradrenergic pain regulation system: a potential target for pain therapy

scientific article published on 13 March 2013

The role of mu-opioid receptors in inflammatory hyperalgesia and alpha 2-adrenoceptor-mediated antihyperalgesia.

scientific article

The role of the dopamine D2 receptor in descending control of pain induced by motor cortex stimulation in the neuropathic rat.

scientific article published on 9 August 2012

Thermal sensation and pain in oral lichen planus and lichenoid reaction

scientific article published on 01 January 2003

Transient receptor potential ankyrin 1 (TRPA1) ion channel in the pathophysiology of peripheral diabetic neuropathy

scientific article published on 01 July 2013

Transient receptor potential ankyrin 1 ion channel contributes to guarding pain and mechanical hypersensitivity in a rat model of postoperative pain

scientific article

Two separate components of pain produced by the submaximal effort tourniquet test.

scientific article published on September 1984

Two-point tactile discrimination ability is influenced by temporal features of stimulation

scientific article published on 26 March 2014

Variation in the dopamine D2 receptor gene plays a key role in human pain and its modulation by transcranial magnetic stimulation

scientific article published on 29 August 2014

Weight bearing of the limb as a confounding factor in assessment of mechanical allodynia in the rat.

scientific article

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