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List of works by João Pedro de Magalhães

A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging

scientific article published on 14 February 2018

A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels

scientific article published on 20 November 2015

A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related

scientific article

A direct communication proposal to test the Zoo Hypothesis

A human tissue-specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence

scientific article published on 27 September 2019

A mathematical model of mortality dynamics across the lifespan combining heterogeneity and stochastic effects.

scientific article

A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms.

scientific article

A method for the permeabilization of live Drosophila melanogaster larvae to small molecules and cryoprotectants

scientific article published on 09 February 2020

A multidimensional systems biology analysis of cellular senescence in aging and disease

scientific article published on 07 April 2020

A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans

scientific article published on 16 December 2015

A new approach for interpreting random forest models and its application to the biology of ageing

scientific article published on 16 February 2018

A proposal to sequence genomes of unique interest for research on aging

scientific article published on 01 June 2007

A review and appraisal of the DNA damage theory of ageing ⬇️

scientific article published on May 10, 2011

A review of supervised machine learning applied to ageing research

scientific article published on 6 March 2017

A review of the biomedical innovations for healthy longevity

scientific article

A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis ⬇️

scientific article published on April 1, 2011

A scan for genes associated with cancer mortality and longevity in pedigree dog breeds

scientific article published on 13 July 2020

A-to-I RNA editing does not change with age in the healthy male rat brain.

scientific article published on 26 May 2013

Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity

scientific article (publication date: April 2013)

Age-related gene-specific changes of A-to-I mRNA editing in the human brain

scientific article

Ageing research in the post-genome era: new technologies for an old problem

scientific article published on 01 January 2009

Ageing-associated changes in the expression of lncRNAs in human tissues reflect a transcriptional modulation in ageing pathways

scientific article published on 09 November 2019

An analysis and validation pipeline for large-scale RNAi-based screens.

scientific article published on 16 January 2013

An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts

scientific article

An integrative analysis of the age-associated multi-omic landscape across cancers

scientific article published on 20 April 2021

Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging

scientific article published on 25 March 2007

Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans

scientific article

Being cool: how body temperature influences ageing and longevity

scientific article

Biohorology and biomarkers of aging: current state-of-the-art, challenges and opportunities

scientific article published on 06 April 2020

Bioinformatics approaches for deciphering the epitranscriptome: Recent progress and emerging topics

scientific article published on 13 June 2020

Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis.

scientific article published in August 2018

Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity.

scientific article published on June 2008

Cells discover fire: employing reactive oxygen species in development and consequences for aging.

scientific article

Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome.

scientific article

Cognitive aging as an extension of brain development: a model linking learning, brain plasticity, and neurodegeneration.

scientific article

Comparing enrichment analysis and machine learning for identifying gene properties that discriminate between gene classes

scientific article published on 20 March 2019

Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes

scientific article

Ecological, biomedical and epidemiological approaches to understanding oxidative balance and ageing: what they can teach each other

scholarly article by Alan A. Cohen et al published 30 July 2010 in Functional Ecology

Endless paces of degeneration--applying comparative genomics to study evolution's moulding of longevity

scientific article published on 12 July 2013

Enhancing Epitranscriptome Module Detection from m6A-Seq Data Using Threshold-Based Measurement Weighting Strategy.

scientific article published on 14 June 2018

Fish oil supplements, longevity and aging

scientific article published on 25 August 2016

From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing.

scientific article published in October 2004

From humans to hydra: patterns of cancer across the tree of life.

scientific article published on 16 April 2018

Gathering insights on disease etiology from gene expression profiles of healthy tissues

scientific article published on 11 October 2011

GenAge: a genomic and proteomic network map of human ageing.

scientific article published in July 2004

Gene co-expression analysis for functional classification and gene-disease predictions

scientific article published on 10 January 2017

Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase

scientific article

GeneFriends: a human RNA-seq-based gene and transcript co-expression database

scientific article

GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases.

scientific article

Genome-environment interactions that modulate aging: powerful targets for drug discovery

scientific article

Genome-wide patterns of genetic distances reveal candidate Loci contributing to human population-specific traits

scientific article published on 22 December 2011

Genomes optimize reproduction: aging as a consequence of the developmental program.

scientific article

Geographic encoding of transcripts enabled high-accuracy and isoform-aware deep learning of RNA methylation

scientific article published in 2022

Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease

scientific article

HAGR: the Human Ageing Genomic Resources

scientific article

Has gene duplication impacted the evolution of Eutherian longevity?

scientific article published on 4 July 2016

How ageing processes influence cancer ⬇️

scientific article published on May 1, 2013

How bioinformatics can help reverse engineer human aging

scientific article published on April 2004

Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing

scientific article

Human disease-associated mitochondrial mutations fixed in nonhuman primates.

scientific article published on 25 August 2005

Identification of polymorphisms in cancer patients that differentially affect survival with age.

scientific article published on 20 October 2017

In memory of Dr. Olivier Toussaint.

scientific article published on 23 January 2017

Insights into the evolution of longevity from the bowhead whale genome ⬇️

scientific article

Insights on cryoprotectant toxicity from gene expression profiling of endothelial cells exposed to ethylene glycol.

scientific article published on 12 October 2015

Is mammalian aging genetically controlled?

scientific article published on 01 January 2003

List of Contributors

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

scientific article published on 16 June 2016

LongevityMap: a database of human genetic variants associated with longevity.

scientific article

MYCN/LIN28B/Let-7/HMGA2 pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging.

scientific article published on 29 April 2013

Machine learning for predicting lifespan-extending chemical compounds

scientific article published on July 2017

Meta-analysis of age-related gene expression profiles identifies common signatures of aging.

scientific article

Mitochondrially encoded methionine is inversely related to longevity in mammals

scientific article

Mutational Bias Plays an Important Role in Shaping Longevity-Related Amino Acid Content in Mammalian mtDNA-Encoded Proteins ⬇️

scientific article published on June 30, 2012

Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence.

scientific article published on 5 February 2018

Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions

scientific article

No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.

scientific article published in June 2004

Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations

scientific article

Osh6 links yeast vacuolar functions to lifespan extension and TOR.

scientific article published on July 2012

Paternal genome effects on aging: Evidence for a role of Rasgrf1 in longevity determination? ⬇️

scientific article published on December 21, 2010

Predicting the Pro-Longevity or Anti-Longevity Effect of Model Organism Genes with New Hierarchical Feature Selection Methods

scientific article published on March 2015

Prediction of C. elegans longevity genes by human and worm longevity networks

scientific article published on 29 October 2012

Programmatic features of aging originating in development: aging mechanisms beyond molecular damage? ⬇️

scientific article published on September 10, 2012

RMDisease V2.0: an updated database of genetic variants that affect RNA modifications with disease and trait implication

scientific article published in 2022

RMDisease: a database of genetic variants that affect RNA modifications, with implications for epitranscriptome pathogenesis

scientific article published on 03 October 2020

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice

scientific article

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

scientific article published on 01 February 2019

Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice

scientific article published on 14 April 2016

Stress, cell senescence and organismal ageing

scientific article

Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts

scientific article published on July 2002

SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes

scientific article published on 26 October 2020

Systematic analysis of the gerontome reveals links between aging and age-related diseases

scientific article

Telomeres and telomerase: a modern fountain of youth?

scientific article

The Business of Anti-Aging Science

scientific article published on August 2017

The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource

scientific article

The DrugAge database of aging-related drugs

scientific article

The Human Ageing Genomic Resources: online databases and tools for biogerontologists.

scientific article

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations

scientific article

The effects of donor age on organ transplants: A review and implications for aging research

scholarly article by Jose Carlos Dayoub published in September 2018

The evolution of mammalian aging

scientific article

The fog of genetics: what is known, unknown and unknowable in the genetics of complex traits and diseases

scientific article published on 21 October 2019

The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS

scientific article published in 2021

The inherent challenges of classifying senescence-Response

scientific article

The role of DNA methylation in aging, rejuvenation, and age-related disease

scientific article

The scientific quest for lasting youth: prospects for curing aging

scientific article

To help aging populations, classify organismal senescence

scientific article

Topological Characterization of Human and Mouse m5C Epitranscriptome Revealed by Bisulfite Sequencing.

scientific article

Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

scientific article published on 11 January 2022

Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.

scientific article published on 22 December 2015

Using deep learning to associate human genes with age-related diseases

scientific article published on 01 April 2020

Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization.

scientific article published on 12 February 2018

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13

scientific article published on 17 August 2020

WHISTLE: a high-accuracy map of the human N6-methyladenosine (m6A) epitranscriptome predicted using a machine learning approach

scientific article published on 01 April 2019

Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome

scientific article (publication date: June 2013)

Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research

scientific article

flowAI: automatic and interactive anomaly discerning tools for flow cytometry data.

scientific article

m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome

scientific article published on 21 August 2020

m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human

scientific article published on 12 March 2020

miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's Disease

scientific article published on 17 January 2020

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