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List of works by Lucio Luzzatto

A Quantitative Measurement of the Human Somatic Mutation Rate

scientific article

A Role for PML in Innate Immunity

scientific article

A ten year review of the sickle cell program in Muhimbili National Hospital, Tanzania

scholarly article by Julie Makani et al published 2018 in BMC hematology

Acquired resistance to imatinib mesylate: selection for pre-existing mutant cells

scientific article published in August 2002

Advances in understanding the pathogenesis of acquired aplastic anaemia

scientific article published on 05 July 2018

Analysis of gene expression profiles reveals novel correlations with the clinical course of colorectal cancer

scientific article

Blood companions

scientific article published in Nature

CD157 is an important mediator of neutrophil adhesion and migration

scientific journal article

CD157 plays a pivotal role in neutrophil transendothelial migration

scientific article published on 17 August 2006

Causality and Chance in the Development of Cancer

scientific article published on 01 July 2015

Causality and chance in oncogenesis

scientific article published in January 2015

Childhood leukaemia and lymphoma: African experience supports a role for environmental factors in leukaemogenesis

scientific article

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase-deficient children receiving dapsone

scientific article published on 19 September 2012

Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab

scientific article published on 29 January 2009

Complement-mediated haemolysis and the role of blood transfusion in paroxysmal nocturnal haemoglobinuria

scientific article

Congenital dyserythropoietic anemia type II in human patients is not due to mutations in the erythroid anion exchanger 1.

scientific article published in October 2003

Correction: Somatic mutations in cancer development.

scientific article published on 28 July 2011

David Galton and the evolution of somatic cell populations

scientific article published on 01 December 2007

Diagnosis and management of paroxysmal nocturnal hemoglobinuria

scientific article

East and West

scientific article published in Nature

Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria

scientific article published on 16 August 2007

Ex vivo enrichment of mesenchymal cell progenitors by fibroblast growth factor 2

scientific article published in July 2003

Expression of Plasmodium falciparum G6PD-6PGL in laboratory parasites and in patient isolates in G6PD-deficient and normal Nigerian children

scientific article published in August 2003

F cell numbers are associated with an X-linked genetic polymorphism and correlate with haematological parameters in patients with sickle cell disease

scientific article published on 19 October 2020

Favism and Glucose-6-Phosphate Dehydrogenase Deficiency

scientific article published in January 2018

Favism, the commonest form of severe hemolytic anemia in Palestinian children, varies in severity with three different variants of G6PD deficiency within the same community

scientific article published on 6 July 2016

Feasibility of evaluating quality cancer care using registry data and electronic health records: a population-based study

scientific article

Frequency of missense mutations in the coding region of a eukaryotic gene transferred by retroviral vectors

scientific article

G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications

scientific article

G6PD deficiency: a polymorphism balanced by heterozygote advantage against malaria

scientific article published on 22 September 2015

G6PD is indispensable for erythropoiesis after the embryonic-adult hemoglobin switch

scientific journal article

Genes expressed in red cells could shape a malaria attack

article

Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry

scientific article

Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita

scientific article published on 30 September 2019

Glucose 6-phosphate dehydrogenase deficiency: from genotype to phenotype

scientific article published on 01 October 2006

Glucose-6-Phosphate Dehydrogenase Deficiency.

scientific article

Glycosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

scientific article published in September 2002

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria

scientific article

Haematology in Africa.

scientific article

Haemoglobin's chaperone

scientific article published in Nature

Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers

scientific article published on 24 July 2017

High frequency of acquired aplastic anemia in Tanzania

scientific article published on 06 February 2019

High incidence of thrombosis in African-American and Latin-American patients with Paroxysmal Nocturnal Haemoglobinuria

scientific article published on 01 January 2005

Highly homologous T-cell receptor beta sequences support a common target for autoreactive T cells in most patients with paroxysmal nocturnal hemoglobinuria

scientific article published on 6 February 2007

Hydroxyurea - An Essential Medicine for Sickle Cell Disease in Africa

scientific article published on 01 January 2019

Imatinib: can one outwit chronic myeloid leukemia?

scientific article published in September 2002

In vivo gene marking of rhesus macaque long-term repopulating hematopoietic cells using a VSV-G pseudotyped versus amphotropic oncoretroviral vector.

scientific article published in April 2004

Independent origin of single and double mutations in the human glucose 6-phosphate dehydrogenase gene

scientific article published in 1996

Inherited and acquired mutations in blood diseases

scientific article published on 01 May 2007

LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis

scientific article published on October 2009

Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania.

scientific article

Making Hydroxyurea Affordable for Sickle Cell Disease in Tanzania is Essential (HASTE): how to meet major health needs at a reasonable cost

scientific article published on 24 September 2020

Management of paroxysmal nocturnal haemoglobinuria: a personal view.

scientific article published on 22 April 2011

Maternally transmitted severe glucose 6-phosphate dehydrogenase deficiency is an embryonic lethal

scientific article

Neutral evolution in paroxysmal nocturnal hemoglobinuria

scholarly article

New Insights into the Pathophysiology of Acquired Cytopenias ⬇️

scientific article published on January 1, 2000

One enzyme from two genes?

scientific article published in Nature

Orphan drugs - Authors' reply

scientific article published on 01 April 2019

Outrageous prices of orphan drugs: a call for collaboration

scientific article published on 20 July 2018

PNH from mutations of another PIG gene ⬇️

scientific article published on August 15, 2013

Paroxysmal Nocturnal Haemoglobinuria

Paroxysmal nocturnal haemoglobinuria (PNH): novel therapies for an ancient disease

scientific article published on 01 November 2020

Paroxysmal nocturnal hemoglobinuria and eculizumab

scientific article published on April 2010

Paroxysmal nocturnal hemoglobinuria--hemolysis before and after eculizumab

scientific article published on December 2010

Paroxysmal nocturnal hemoglobinuria: Significant association with specific HLA-A, -B, -C, and -DR alleles in an Italian population

scientific article published in March 2008

Paroxysmal nocturnal hemoglobinuria: an acquired X-linked genetic disease with somatic-cell mosaicism

scientific article

Patients with paroxysmal nocturnal hemoglobinuria have a high frequency of peripheral-blood T cells expressing activating isoforms of inhibiting superfamily receptors

scientific article published in October 2005

Polymorphism of the complement receptor 1 gene correlates with the hematologic response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

scientific article published on 13 September 2013

Primaquine-induced haemolysis in females heterozygous for G6PD deficiency

scientific article

Rare diseases and effective treatments: are we delivering?

scientific article

Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

scientific article published on 14 December 2012

Recent advances in biological and clinical aspects of paroxysmal nocturnal hemoglobinuria

scientific article published on August 2006

Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria

scientific article published in 2016

Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells

scientific article published in December 2002

Resistance to "castration-resistant".

scientific article published on 17 February 2014

Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

scientific article

Severe telomere shortening in patients with paroxysmal nocturnal hemoglobinuria affects both GPI- and GPI+ hematopoiesis

scientific article published on 13 March 2003

Sickle cell anaemia and malaria

scientific article

Somatic mutations and the hierarchy of hematopoiesis ⬇️

scientific article published on August 27, 2010

Somatic mutations in cancer development ⬇️

scientific article published on April 5, 2011

Sterile 'Abscess' of the Spleen and the Sickle Cell Trait

scientific article published in January 2018

Synthesis of the essential core of the human glycosylphosphatidylinositol (GPI) anchor

scientific article published in April 2011

TMPRSS2:ERG fusion gene and androgen-ablation therapy in prostate cancer

scientific article published on 01 July 2010

The "escape" model: a versatile mechanism for clonal expansion

scientific article

The European Cancer Patient's Bill of Rights, update and implementation 2016. ⬇️

scientific article

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria

scientific article

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment

scientific article published on 10 May 2012

The frequency of granulocytes with spontaneous somatic mutations: a wide distribution in a normal human population

scientific article

The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH).

scientific article published on 16 March 2006

The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics

scientific article

The use of PIG-A as a sentinel gene for the study of the somatic mutation rate and of mutagenic agents in vivo

scientific article published on 24 December 2009

The zinc finger gene ZIC2 has features of an oncogene and its overexpression correlates strongly with the clinical course of epithelial ovarian cancer

scientific article

Thrombolytic therapy is effective in paroxysmal nocturnal hemoglobinuria: a series of nine patients and a review of the literature

scientific article

Transcriptional functionality of germ line p53 mutants influences cancer phenotype.

scientific article

Two founder mutations in the SEC23B gene account for the relatively high frequency of CDA II in the Italian population

scientific article published on September 2011

correspondence: Pregnancy in PNH: another eculizumab baby

scientific article published in September 2010

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