List of works by Frank Plummer

A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort

scientific article

A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers

scientific article published in May 2009

A common human leucocyte antigen-DP genotype is associated with resistance to HIV-1 infection in Kenyan sex workers

scientific article published on October 2008

A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells

scientific article

A comparison of parallel pyrosequencing and sanger clone-based sequencing and its impact on the characterization of the genetic diversity of HIV-1.

scientific article

A genetic polymorphism of FREM1 is associated with resistance against HIV infection in the Pumwani sex worker cohort

scientific article

A naturally occurring Vif mutant (I107T) attenuates anti-APOBEC3G activity and HIV-1 replication

scientific article published on 23 May 2013

A novel HIV vaccine targeting the protease cleavage sites

scientific article published on 12 September 2017

Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015

Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya

scientific article published on 22 October 2013

Altered dendritic cell-natural killer interaction in Kenyan sex workers resistant to HIV-1 infection

scientific article published on February 2012

An Outbreak of Human Coronavirus OC43 Infection and Serological Cross-reactivity with SARS Coronavirus

scientific article

An integrative bioinformatic approach for studying escape mutations in human immunodeficiency virus type 1 gag in the Pumwani Sex Worker Cohort

scientific article

Analysis of multimerization of the SARS coronavirus nucleocapsid protein

scientific article published in April 2004

Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells

scientific article

Anti-HIV-1 activity of elafin is more potent than its precursor's, trappin-2, in genital epithelial cells

scientific article published on 15 February 2012

Antigen-specific gene expression profiles of peripheral blood mononuclear cells do not reflect those of T-lymphocyte subsets

scientific article published on September 2004

Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study

scientific article

Association of sex work with reduced activation of the mucosal immune system

scientific article published on 12 January 2014

Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls

scientific article

Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort

scientific article published in May 2008

Associations of human leukocyte antigen-G with resistance and susceptibility to HIV-1 infection in the Pumwani sex worker cohort

scientific article published in January 2013

Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment

scientific article published in December 2008

Bacterial vaginosis, HIV serostatus and T-cell subset distribution in a cohort of East African commercial sex workers: retrospective analysis

scientific article

Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya

scientific article

CD26/dipeptidyl peptidase IV (CD26/DPPIV) is highly expressed in peripheral blood of HIV-1 exposed uninfected female sex workers

scientific article

CD4+ T cell responses in HIV-exposed seronegative women are qualitatively distinct from those in HIV-infected women

scientific article published in December 2004

Cell phones: tightening the communication gap in resource-limited antiretroviral programmes?

scientific article published in November 2006

Cellular immune responses to recurring influenza strains have limited boosting ability and limited cross reactivity to other strains

article

Cervical HIV-specific IgA in a population of commercial sex workers correlates with repeated exposure but not resistance to HIV.

scientific article

Chancroid: A rediscovered disease

Characterization of CD8 T-cell responses in HIV-1-exposed seronegative commercial sex workers from Nairobi, Kenya

scientific article

Characterization of an HLA-C-restricted CTL response in chronic HIV infection.

scientific article published in April 2010

Characterization of protein-protein interactions between the nucleocapsid protein and membrane protein of the SARS coronavirus

scientific article published in October 2004

Clade-specific evolution mediated by HLA-B*57/5801 in human immunodeficiency virus type 1 clade A1 p24.

scientific article published on 16 September 2009

Clinical Evaluation of Ebola Virus Disease Therapeutics

scientific article

Construction of an infectious HIV type 1 molecular clone from an African patient with a subtype D/C Recombinant Virus

scientific article published in September 2004

Correction: Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers

scientific article published on 21 July 2015

Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection.

scientific article

Cross-Clade HIV-1–Specific Neutralizing IgA in Mucosal and Systemic Compartments of HIV-1–Exposed, Persistently Seronegative Subjects

article

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

scientific article published in May 2002

Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cells

scientific article published in May 2009

Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units

scientific article published on 18 March 2005

Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus

scientific article

Development of functional human monoclonal single-chain variable fragment antibody against HIV-1 from human cervical B cells

scientific article published on 01 April 2003

Development of monoclonal antibodies to interrogate functional domains and isoforms of FREM1 protein.

scientific article published in April 2014

Diversity and Frequencies of HLA Class I and Class II Genes of an East African Population

article

Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case-control study

scientific article published in April 2012

Effect of baseline HIV disease parameters on CD4+ T cell recovery after antiretroviral therapy initiation in Kenyan women

scientific article

Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial ⬇️

scientific article published on November 9, 2010

Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers

scientific article published on 27 July 2005

Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition

scientific article

Elevated expression of LAG-3, but not PD-1, is associated with impaired iNKT cytokine production during chronic HIV-1 infection and treatment

scientific article

Elevation of immune activation in kenyan women is associated with alterations in immune function: implications for vaccine development

article

Enrichment of LAG-3, but not PD-1, on double negative T cells at the female genital tract

scientific article

Enrichment of variations in KIR3DL1/S1 and KIR2DL2/L3 among H1N1/09 ICU patients: an exploratory study

scientific article (publication date: 2011)

Epigenetic control of IRF1 responses in HIV-exposed seronegative versus HIV-susceptible individuals

scientific article

Epitope cross-reactivity frequently differs between central and effector memory HIV-specific CD8+ T cells.

scientific article published in March 2007

Epitope mapping of HIV-specific CD8+ T cell responses by multiple immunological readouts reveals distinct specificities defined by function

scientific article

Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection

scientific article

Evaluation of a quantitative real-time PCR assay to measure HIV-specific mucosal CD8+ T cell responses in the cervix

scientific article

Experimental countermeasures against Ebola virus: current progress and an ethical conundrum

scientific article

For protection from HIV-1 infection, more might not be better: a systematic analysis of HIV Gag epitopes of two alleles associated with different outcomes of HIV-1 infection

scientific article published on 9 November 2011

From bench to almost bedside: the long road to a licensed Ebola virus vaccine

scientific article published on 17 November 2017

Full-length HIV type 1 proviral sequencing of 10 highly exposed women from Nairobi, Kenya reveals a high proportion of intersubtype recombinants.

scientific article

Genital levels of soluble immune factors with anti-HIV activity may correlate with increased HIV susceptibility

scientific article published on October 2008

Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers

scientific article published on 30 April 2002

HIV and interferon regulatory factor 1: a story of manipulation and control

scientific article published on 25 September 2013

HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition

scientific article published in June 2010

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis

scientific article published in October 2004

HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers

scientific article

HIV-1 Subtypes and 5'LTR-Leader Sequence Variants Correlate with Seroconversion Status in Pumwani Sex Worker Cohort

scientific article published on 23 December 2017

HIV-1 clade D is associated with increased rates of CD4 decline in a Kenyan cohort

scientific article

HIV-1 neutralizing activity is correlated with increased levels of chemokines in saliva of HIV-1-exposed uninfected individuals.

scientific article published in January 2008

HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression

scientific article published on 17 June 2015

HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progression.

scientific article

HIV-specific T cells: strategies for fighting a moving target

scientific article

HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factors

scientific article

HLA Class II Antigens and Their Interactive Effect on Perinatal Mother-To-Child HIV-1 Transmission

scientific article

HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades

scientific article

HLA-G and mother-child perinatal HIV transmission

scientific article published on 10 December 2012

Haemophilus ducreyi

Heterogeneity in host HIV susceptibility as a potential contributor to recent HIV prevalence declines in Africa

scientific article published on January 2009

High pH reversed-phase chromatography as a superior fractionation scheme compared to off-gel isoelectric focusing for complex proteome analysis

scientific article

High prevalence of genetically similar HIV-1 recombinants among infected sex workers in Nairobi, Kenya

scientific article published on November 2008

Host Genetics and Resistance to HIV-1 Infection

article

Human immunodeficiency virus (HIV) type 1 proviral hypermutation correlates with CD4 count in HIV-infected women from Kenya

scientific article published on 11 June 2008

Human infection with a triple-reassortant swine influenza A(H1N1) virus containing the hemagglutinin and neuraminidase genes of seasonal influenza virus.

scientific article

Human interferon regulatory factor-1 gene and its promoter sequences revealed by population-based complete gene sequencing

scientific article

Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection

scientific article published in April 2008

Hypothetical endogenous SIV-like antigens in Mauritian cynomolgus macaques.

scientific article published on 28 February 2018

IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation

scientific article published in February 2006

Identification and Characterization of Positively Selected Mutations in Nef of Four HIV-1 Major Subtypes from Los Alamos National Laboratory.

scientific article

Identification and characterization of HLA-A*0301 epitopes in HIV-1 gag proteins using a novel approach

scientific article

Identification of HLA-DPA1*020107 in an individual of Ugandan descent

scientific article published on 12 May 2010

Identification of HLA-G*01:17, a new allele possibly generated by an interloci gene conversion event involving exon 3 of HLA-B.

scientific article published on 13 December 2010

Identification of a novel DPA1 allele, DPA1*010602, in an East African population

scientific article published on 07 October 2008

Identification of differentially expressed proteins in the cervical mucosa of HIV-1-resistant sex workers

scientific article published on 16 August 2008

Identification of four novel HLA-A alleles from an East African population by high-resolution sequence-based typing

scientific article published on 10 August 2006

Identification of four novel KIR2DL2 alleles and two novel KIR2DL3 alleles in an East African population

scientific article published on 25 September 2010

Identification of novel human leukocyte antigen G alleles in an East African population by high-resolution sequence-based typing

scientific article

Identification of two novel HLA-C alleles, Cw*070105 and Cw*1408, from East African women

scientific article

Immunogenicity of sequences around HIV-1 protease cleavage sites: potential targets and population coverage analysis for a HIV vaccine targeting protease cleavage sites

scientific article published on 10 May 2013

Influence of HLA class I haplotypes on HIV-1 seroconversion and disease progression in Pumwani sex worker cohort

scientific article

Interferon regulatory factor 1 polymorphisms previously associated with reduced HIV susceptibility have no effect on HIV disease progression

scientific article

Interferon responses in HIV infection: from protection to disease

scientific article published on January 2014

KIR3DL1 alleles and their Epistatic Interactions with HLA Class I Influence Resistance and Susceptibility to HIV-1 acquisition in the Pumwani Sex Worker cohort

scientific article published on 26 December 2017

Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations

scientific article

Mass spectrometric characterization of proteins from the SARS virus: a preliminary report

scientific article

Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state

scientific article

Modelling HIV/AIDS epidemics in Botswana and India: impact of interventions to prevent transmission

scientific article

Molecular characterization of a panel of murine monoclonal antibodies specific for the SARS-coronavirus

scientific article published in January 2005

Molecular characterization of the cervical and systemic B-cell repertoire: Unique, yet overlapping, immune compartments of an HIV-1 resistant individual

scientific article

Molecular definition of vaginal microbiota in East African commercial sex workers

scientific article

Molecular typing of a Legionella pneumophila outbreak in Ontario, Canada

scientific article

Mucosal serpin A1 and A3 levels in HIV highly exposed sero-negative women are affected by the menstrual cycle and hormonal contraceptives but are independent of epidemiological confounders

scientific article

Multiple T-cell epitopes overlap positively-selected residues in the p1 spacer protein of HIV-1 gag.

scientific article published on April 2009

Multiplex detection of bacteria associated with normal microbiota and with bacterial vaginosis in vaginal swabs by use of oligonucleotide-coupled fluorescent microspheres

scientific article published on 30 September 2009

Mx2 expression is associated with reduced susceptibility to HIV infection in highly exposed HIV seronegative Kenyan sex workers

scientific article published on January 2015

Natural and cross-inducible anti-SIV antibodies in Mauritian cynomolgus macaques

scientific article published on 5 October 2017

Naturally occurring protease inhibitor resistance mutations and their frequencies in HIV proviral sequences of drug-naïve sex workers in Nairobi, Kenya

scientific article published on 7 January 2014

Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract

scientific article published on March 2007

Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology

scientific article

Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers

scientific article

Novel interferon regulatory factor-1 polymorphisms in a Kenyan population revealed by complete gene sequencing

scientific article

Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers

scientific article

Potential intensive care unit ventilator demand/capacity mismatch due to novel swine-origin H1N1 in Canada

scientific article

Presence of CD8+ T cells in the ectocervical mucosa correlates with genital viral shedding in HIV-infected women despite a low prevalence of HIV RNA-expressing cells in the tissue

scientific article

Pyrosequencing of the chaperonin-60 universal target as a tool for determining microbial community composition

scientific article

QUASI analysis of host immune responses to Gag polyproteins of human immunodeficiency virus type 1 by a systematic bioinformatics approach

scientific article published on August 2010

Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women

scientific article published in May 2003

Recombination following superinfection by HIV-1.

scientific article published in January 2004

Reduced HIV Risk-Taking and Low HIV Incidence After Enrollment and Risk-Reduction Counseling in a Sexually Transmitted Disease Prevention Trial in Nairobi, Kenya

article

Reduced HIV risk-taking and low HIV incidence after enrollment and risk-reduction counseling in a sexually transmitted disease prevention trial in Nairobi, Kenya

scientific article published in May 2002

Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: a potential mechanism mediating resistance to infection by HIV-1.

scientific article published in May 2010

Reduced cellular susceptibility to in vitro HIV infection is associated with CD4+ T cell quiescence

scientific article

Reduced rates of HIV acquisition during unprotected sex by Kenyan female sex workers predating population declines in HIV prevalence

scientific article published on January 2008

Reducing IRF-1 to Levels Observed in HESN Subjects Limits HIV Replication, But Not the Extent of Host Immune Activation

scientific article published on 27 October 2015

Relative HIV resistance in kenyan sex workers is not due to an altered prevalence or mucosal immune impact of herpes simplex virus type 2 infection.

scientific article published in September 2009

Salivary basic proline-rich proteins are elevated in HIV-exposed seronegative men who have sex with men.

scientific article published in September 2012

Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes

scientific article published in July 2004

Selection, phenotyping and identification of acid and hydrogen peroxide producing bacteria from vaginal samples of Canadian and East African women

scientific article

Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

scientific article published on 12 March 2004

Sex, microbial translocation, and the African HIV epidemic

scientific article published on 18 August 2009

Stable CD4 expression and local immune activation in the ectocervical mucosa of HIV-infected women

scientific article published on 4 September 2013

Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection

scientific article published on September 2006

Structural insights into immune recognition of the severe acute respiratory syndrome coronavirus S protein receptor binding domain

scientific article

Substantial intrapatient differences in the breadth and specificity of HIV-specific CD8+ T-cell interferon-gamma and proliferation responses.

scientific article published in October 2008

Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies

scientific article published on June 2012

Systematic analysis of host immunological pressure on the envelope gene of human immunodeficiency virus type 1 by an immunobioinformatics approach

scientific article published on June 2008

The Genome sequence of the SARS-associated coronavirus

scientific article

The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol

scientific article published on 22 September 2009

The Microbiological Context of HIV Resistance: Vaginal Microbiota and Mucosal Inflammation at the Viral Point of Entry

scientific article published on 14 March 2012

The frequencies of naturally occurring protease inhibitor resistance mutations in HIV proviral sequences of drug naïve sex workers in Nairobi, Kenya and their correlation with host immune response driven positively selected mutations in HIV-1

article

The interaction of HIV infection and other sexually transmitted diseases

The interaction of HIV infection and other sexually transmitted diseases

article

The role of G protein gene GNB3 C825T polymorphism in HIV-1 acquisition, progression and immune activation

scientific article published on 3 January 2012

The shaping of modern human immune systems by multiregional admixture with archaic humans

scientific article

The story of Canada's Ebola vaccine

scientific article published in October 2017

Toll-like Interleukin 1 Receptor Regulator Is an Important Modulator of Inflammation Responsive Genes

article

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection

scientific article published in March 2008

Virulence differences of closely related pandemic 2009 H1N1 isolates correlate with increased inflammatory responses in ferrets

scientific article

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