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List of works by Henry Markram

25th Annual Computational Neuroscience Meeting: CNS-2016

scientific article

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2.

scientific article published on 18 August 2017

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3.

scientific article

A Brief History of Simulation Neuroscience

A Cell Atlas for the Mouse Brain

scholarly article by Csaba Erö et al published 2018 in Frontiers in Neuroinformatics

A Component-Based Extension Framework for Large-Scale Parallel Simulations in NEURON.

scientific article published on 27 April 2009

A Derived Positional Mapping of Inhibitory Subtypes in the Somatosensory Cortex

scientific article published on 06 August 2019

A Hierarchical Structure of Cortical Interneuron Electrical Diversity Revealed by Automated Statistical Analysis ⬇️

scientific article published on September 17, 2012

A Kinetic Map of the Homomeric Voltage-Gated Potassium Channel (Kv) Family

scientific article published on 20 August 2019

A Model for Real-Time Computation in Generic Neural Microcircuits ⬇️

scientific article published in January 2003

A Process for Digitizing and Simulating Biologically Realistic Oligocellular Networks Demonstrated for the Neuro-Glio-Vascular Ensemble

scientific article published on 25 September 2018

A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation

scientific article published on 10 November 2021

A Topological Representation of Branching Neuronal Morphologies

scientific article

A biophysically detailed model of neocortical local field potentials predicts the critical role of active membrane currents

scientific article

A computer-assisted multi-electrode patch-clamp system

scientific article published on 18 October 2013

A history of spike-timing-dependent plasticity

scientific article (publication date: 2011)

A neuron membrane mesh representation for visualization of electrophysiological simulations

scientific article

A new mechanism for memory: neuronal networks rewiring in the young rat neocortex

scientific article published in December 2006

A novel multiple objective optimization framework for constraining conductance-based neuron models by experimental data

scientific article

A null model of the mouse whole-neocortex micro-connectome

scientific article published on 29 August 2019

A synaptic organizing principle for cortical neuronal groups

scientific article

A versatile clearing agent for multi-modal brain imaging

scientific article published on 7 May 2015

A06 Effects of mutant huntingtin on cortical neuron connectivity and activity dependent gene expression

article

Abnormal fear conditioning and amygdala processing in an animal model of autism

scientific article

An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

scientific article published on 7 May 2015

An algorithm for modifying neurotransmitter release probability based on pre- and postsynaptic spike timing.

scientific article

An algorithm to predict the connectome of neural microcircuits

scientific article

Anatomical and functional differentiation of glutamatergic synaptic innervation in the neocortex

scientific article

Anatomical, physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat

scientific article

Anatomical, physiological, molecular and circuit properties of nest basket cells in the developing somatosensory cortex

scientific article

Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron

scientific article

Anti-obesity and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin secretion and functional impact on food intake and gastric emptying

scientific journal article

Bio-physically plausible visualization of highly scattering fluorescent neocortical models for in silico experimentation

scientific article

Bioinformatics: industrializing neuroscience

scientific article published in January 2007

Blue Brain Knowledge Graph: Leveraging Semantic Web Technologies for Simulation Neuroscience

scientific article published in proceedings of the iswc 2023 posters, demos and industry tracks: from novel ideas to industrial practice

Blue Brain Nexus: An open, secure, scalable system for knowledge graph management and data-driven science

scientific article published in 2022

BluePyOpt: Leveraging Open Source Software and Cloud Infrastructure to Optimise Model Parameters in Neuroscience ⬇️

scientific article

Brief bursts self-inhibit and correlate the pyramidal network.

scientific article

Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts

scientific article published on 21 December 2008

Caries Detection with Near-Infrared Transillumination Using Deep Learning

scientific article published on 26 August 2019

Cell Densities in the Mouse Brain: A Systematic Review

article

Cell type- and activity-dependent extracellular correlates of intracellular spiking.

scientific article published on 20 May 2015

Cellular, Synaptic and Network Effects of Acetylcholine in the Neocortex

Channelpedia: An Integrative and Interactive Database for Ion Channels ⬇️

scientific article published on December 30, 2011

Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function

scientific article

Coding and learning of behavioral sequences

scientific article published on January 2004

Coding of temporal information by activity-dependent synapses

scientific article published on 01 January 2002

Combinatorial expression rules of ion channel genes in juvenile rat (Rattus norvegicus) neocortical neurons

scientific article

Competitive calcium binding: implications for dendritic calcium signaling

scientific article published on July 1, 1998

Computing the size and number of neuronal clusters in local circuits

scientific article published on 19 February 2013

Correction: Effective Stimuli for Constructing Reliable Neuron Models.

scientific article published on 6 June 2013

Correlation maps allow neuronal electrical properties to be predicted from single-cell gene expression profiles in rat neocortex

scientific article published on 10 June 2004

Corrigendum: A Cell Atlas for the Mouse Brain

scholarly article published in Frontiers in Neuroinformatics

Cortical reliability amid noise and chaos

scientific article published on 22 August 2019

Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices

scientific article

Data-Driven Modeling of Cholinergic Modulation of Neural Microcircuits: Bridging Neurons, Synapses and Network Activity

Deriving physical connectivity from neuronal morphology.

scientific article published in March 2003

Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments

scientific article published on 12 July 2010

Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells

scientific article

Dynamics of population rate codes in ensembles of neocortical neurons

scientific article published on 01 February 2004

Effective stimuli for constructing reliable neuron models

scientific article

Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid

scholarly article

Enhanced long term microcircuit plasticity in the valproic acid animal model of autism ⬇️

scientific article published on June 24, 2009

Ephaptic coupling of cortical neurons.

scientific article

Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex

scientific article published on 15 October 2019

Evaluating automated parameter constraining procedures of neuron models by experimental and surrogate data

scientific article

Excitation states of metabolic networks predict dose-response fingerprinting and ligand pulse phase signalling

scientific article published on 19 December 2019

Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons

scholarly article published 4 January 2019

Experimentally-constrained biophysical models of tonic and burst firing modes in thalamocortical neurons.

scientific article

Fading memory and kernel properties of generic cortical microcircuit models

scientific article

Fixing the location and dimensions of functional neocortical columns

scientific article published on 23 May 2008

Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex

scientific article published on 21 September 2009

From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

scientific article published on 09 June 2016

Fully implicit parallel simulation of single neurons

scientific article published on April 2008

General developmental health in the VPA-rat model of autism ⬇️

scientific article published on July 24, 2013

Henry Markram: A brain in a supercomputer

TEDGlobal 2009

Heterogeneity in the pyramidal network of the medial prefrontal cortex

scientific article published on 19 March 2006

Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism

scientific article published on 29 October 2008

Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid

scientific article

Impact of higher order network structure on emergent cortical activity

scientific article published on 01 March 2020

Individual differences in sensory sensitivity: Further lessons from an Autism model

scientific article published on 27 March 2019

Inferring connection proximity in networks of electrically coupled cells by subthreshold frequency response analysis

scientific article published on 28 November 2007

Information processing with frequency-dependent synaptic connections.

scientific article published in July 1998

Innate neural assemblies for lego memory

scientific article published on 16 May 2011

Input prediction and autonomous movement analysis in recurrent circuits of spiking neurons

scientific article

Interactive visualization and analysis of morphological skeletons of brain vasculature networks with VessMorphoVis

scientific article published on 01 July 2020

Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits

scientific article

Interneuron Diversity series: Molecular and genetic tools to study GABAergic interneuron diversity and function

scientific article published on February 2004

Interneurons of the neocortical inhibitory system

scientific article (publication date: October 2004)

Intrinsic morphological diversity of thick-tufted layer 5 pyramidal neurons ensures robust and invariant properties of in silico synaptic connections

scientific article published on 14 November 2011

Introducing the Human Brain Project

Matched Pre- and Post-Synaptic Changes Underlie Synaptic Plasticity over Long Time Scales ⬇️

scientific article published on April 10, 2013

Microcircuits in action--from CPGs to neocortex

scientific article

Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons

scientific article

Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties

scientific article

Morphological Development of Thick-Tufted Layer V Pyramidal Cells in the Rat Somatosensory Cortex ⬇️

scientific article published on February 17, 2011

Morphological Diversity Strongly Constrains Synaptic Connectivity and Plasticity

scientific article published on 20 June 2017

Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex

scientific article published on 23 November 2006

Multiquantal release underlies the distribution of synaptic efficacies in the neocortex

scientific article published on 24 November 2009

NEOBASE: databasing the neocortical microcircuit.

scientific article published in January 2005

Network-Related Challenges and Insights from Neuroscience

Network-timing-dependent plasticity

scientific article

Neural codes: firing rates and beyond

scientific article

Neural networks with dynamic synapses ⬇️

scientific article published in May 1998

NeuroMorphoVis: a collaborative framework for analysis and visualization of neuronal morphology skeletons reconstructed from microscopy stacks.

scientific article published in July 2018

Neuropeptide and calcium-binding protein gene expression profiles predict neuronal anatomical type in the juvenile rat.

scientific article published on 9 June 2005

Neuroscience thinks big (and collaboratively).

scientific article published in September 2013

New insights into the classification and nomenclature of cortical GABAergic interneurons

scientific article published on 6 February 2013

Newsmaker interview: Henry Markram. Blue Brain founder responds to critics, clarifies his goals. Interview by Greg Miller

scientific article published in November 2011

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro

scientific article

Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate

scientific article published on 30 August 2018

Objective Morphological Classification of Neocortical Pyramidal Cells

scientific article published on 01 April 2019

Organizing principles for a diversity of GABAergic interneurons and synapses in the neocortex

scientific article

Parallel network simulations with NEURON.

scientific article published on 26 May 2006

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

scientific article

Physically-based in silico light sheet microscopy for visualizing fluorescent brain models

scientific article published on 13 August 2015

Potential for multiple mechanisms, phenomena and algorithms for synaptic plasticity at single synapses.

scientific article

Predictable enriched environment prevents development of hyper-emotionality in the VPA rat model of autism

scientific article published on 2 June 2015

Predicting neuronal activity with an adaptive exponential integrate-and-fire model.

scientific article published on 6 July 2007

Preserving axosomatic spiking features despite diverse dendritic morphology ⬇️

scientific article published on March 27, 2013

Real-time computing without stable states: a new framework for neural computation based on perturbations

scientific article (publication date: November 2002)

Reconstruction and Simulation of Neocortical Microcircuitry.

scientific article published on October 2015

Reconstruction and visualization of large-scale volumetric models of neocortical circuits for physically-plausible in silico optical studies

scientific article published on 13 September 2017

Rich cell-type-specific network topology in neocortical microcircuitry.

scientific article published on 05 June 2017

Seven challenges for neuroscience

scientific article

Short-term ionic plasticity at GABAergic synapses ⬇️

scientific article published on October 16, 2012

Short-term synaptic plasticity orchestrates the response of pyramidal cells and interneurons to population bursts

scientific article published in June 2005

Single-cell RT-PCR, a technique to decipher the electrical, anatomical, and genetic determinants of neuronal diversity

scientific article published in January 2007

Single-cell RT-PCR, a technique to decipher the electrical, anatomical, and genetic determinants of neuronal diversity

scientific article

Slow oscillations in neural networks with facilitating synapses

scientific article published on 16 May 2008

Spike frequency adaptation and neocortical rhythms

scientific article published in August 2002

Spike-timing-dependent plasticity: a comprehensive overview

scientific article published on 12 July 2012

Spontaneous and evoked synaptic rewiring in the neonatal neocortex

scientific article

Statistical connectivity provides a sufficient foundation for specific functional connectivity in neocortical neural microcircuits

scientific article

Stereotypy in neocortical microcircuits

scientific article

Substrate arrays of iridium oxide microelectrodes for in vitro neuronal interfacing

scientific article published on 22 January 2009

Synapses as dynamic memory buffers

scientific article published in March 2002

Synaptic and cellular organization of layer 1 of the developing rat somatosensory cortex

scientific article published on January 2013

Synaptic dynamics control the timing of neuronal excitation in the activated neocortical microcircuit

scientific article published on 20 February 2004

Synaptic pathways in neural microcircuits.

scientific article

Synchrony generation in recurrent networks with frequency-dependent synapses.

scientific article published on January 2000

The Blue Brain Project: building the neocortical column.

scientific article published on 6 July 2007

The Blue Brain Project: calibrating the neocortical column.

scientific article published on 6 July 2007

The Intense World Theory – A Unifying Theory of the Neurobiology of Autism ⬇️

scientific article published on December 21, 2010

The blue brain project

scientific article

The death of Cajal and the end of scientific romanticism and individualism

scientific article published in October 2014

The future of human cerebral cartography: a novel approach

scientific article

The human brain project

scientific article published on 01 June 2012

The intense world syndrome--an alternative hypothesis for autism

scientific article

The modular cross-synaptic nature of LTP/LTD following on-going neural activity

scientific article

The neocortical column

scientific article published in 2012

The neocortical microcircuit as a tabula rasa

scientific article

The neocortical microcircuit collaboration portal: a resource for rat somatosensory cortex

scientific article

The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow

scientific article published on 17 September 2018

Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically Encoded pH Sensors

scientific article published on June 2016

Timed Synaptic Inhibition Shapes NMDA Spikes, Influencing Local Dendritic Processing and Global I/O Properties of Cortical Neurons

scientific article published in November 2017

“The Blue Brain Project”

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