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List of works by Jan Nolta

"Next-generation" mesenchymal stem or stromal cells for the in vivo delivery of bioactive factors: progressing toward the clinic

scientific article published in April 2016

19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons.

scientific article published on 6 February 2007

Adhesion to fibronectin maintains regenerative capacity during ex vivo culture and transduction of human hematopoietic stem and progenitor cells

scientific article published in December 1998

Advances in bone marrow stem cell therapy for retinal dysfunction

scientific article published on 23 October 2016

Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts.

scientific article published on 4 February 2016

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

scientific article

Analysis of optimal conditions for retroviral-mediated transduction of primitive human hematopoietic cells

scientific article

Animal xenograft models for evaluation of gene transfer into human hematopoietic stem cells.

scientific article

Autoimmune T cells lured to a FASL web of death by MSCs

scientific article published in May 2012

Autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide purged marrows for children with acute non-lymphoblastic leukemia in second remission

scientific article

Autologous myoblasts attenuate atrophy and improve tongue force in a denervated tongue model: a pilot study

scientific article published in October 2013

BMI1 Regulation of Self-Renewal and Multipotency in Human Mesenchymal Stem Cells.

scientific article

Biology of umbilical cord blood progenitors in bone marrow niches

scientific article published on 19 March 2007

Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells.

scientific article published on February 2005

CD25 preselective anti-HIV vectors for improved HIV gene therapy

scientific article

Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury

scientific article published on 17 January 2014

Characterization andIn VivoTesting of Mesenchymal Stem Cells Derived from Human Embryonic Stem Cells ⬇️

scientific article published on March 4, 2011

Clinical infection control in gene therapy: a multidisciplinary conference.

scientific article

Clinical translation of stem cells: insight for cartilage therapies

scientific article

Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells

scientific article

Clonal diversity of primitive human hematopoietic progenitors following retroviral marking and long-term engraftment in immune-deficient mice.

scientific article published in December 1997

Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates

scientific article published on 17 March 2003

Companion animals: Translational scientist's new best friends

scientific article

Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells

scientific article

Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling

scientific article

Computational analysis of contractility in engineered heart tissue

scientific article published on 22 February 2012

Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine

scientific article published on 07 August 2015

Concise Review: Stem Cells in Osteoimmunology

scientific article published on 8 April 2017

Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: progress toward safe clinical products.

scientific article published on January 2012

Concise review: MicroRNA function in multipotent mesenchymal stromal cells.

scientific article published on May 2014

Contribution of human hematopoietic stem cells to liver repair.

scientific article published on 17 June 2009

Crosstalk between adrenergic and toll-like receptors in human mesenchymal stem cells and keratinocytes: a recipe for impaired wound healing

scientific article

Cutting Edge Advances in Stem Cell Biology and Therapy

scientific article

Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow.

scientific article published on 9 November 2006

Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice

scientific article published on April 2011

Developing stem cell therapies for juvenile and adult-onset Huntington's disease

scientific article

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass

scientific article published on 05 February 2012

Dissecting the genetic architecture of coronary artery disease by genome engineering.

scientific article

Editorial: 2013 - a year of clinical success and great scientific innovation in the stem cell field

scientific article published on 01 January 2014

Editorial: Our top 10 developments in stem cell biology over the last 30 years

scientific article published in January 2012

Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus

scientific article published on 29 August 2018

Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy

scientific article

Efficient Generation of Induced Pluripotent Stem and Neural Progenitor Cells From Acutely Harvested Dura Mater Obtained During Ventriculoperitoneal Shunt Surgery.

scientific article published on 11 June 2015

Electrical Guidance of Human Stem Cells in the Rat Brain

scientific article published on 28 June 2017

Engineered BDNF producing cells as a potential treatment for neurologic disease

scientific article published on 9 May 2016

Engraftment and retroviral marking of CD34+ and CD34+CD38- human hematopoietic progenitors assessed in immune-deficient mice.

scientific article

Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

scientific article

Enhancing Retention of Mesenchymal Stem Cells with Pro-survival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia

scientific article published on 18 December 2018

Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations

scientific article published on 18 February 2011

Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro

scientific article

Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin ⬇️

scientific article published on 08 December 2011

Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion ⬇️

scientific article published on 26 February 2019

Expression of human glucocerebrosidase following retroviral vector-mediated transduction of murine hematopoietic stem cells

scientific article published in November 1991

Expression of human glucocerebrosidase in murine long-term bone marrow cultures after retroviral vector-mediated transfer.

scientific article published on February 1990

FLT3 ligand preserves the ability of human CD34+ progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction

scientific article published on 01 January 1997

Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice.

scientific article

Feasibility Study of Canine Epidermal Neural Crest Stem Cell Transplantation in the Spinal Cords of Dogs

scientific article

Fibroblast Growth Factor 2 Regulates High Mobility Group A2 Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells

scientific article published on 16 February 2016

Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.

scientific article

Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells

scientific article

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity

scientific article published on 3 June 2004

Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells

scientific article published on 30 November 2010

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.

scientific article

Generation of human vascularized brain organoids

scientific article published on 01 May 2018

Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease

scientific article published on 9 December 2011

Guided migration of neural stem cells derived from human embryonic stem cells by an electric field

scientific article

Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways.

scientific article published in March 2017

Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells

scientific article published on 16 May 2013

Human Hematopoietic Cell Culture, Transduction, and Analyses

article

Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models.

scientific article published on 14 January 2016

Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy.

scientific article

Human Thymus Mesenchymal Stromal Cells Augment Force Production in Self-Organized Cardiac Tissue ⬇️

scientific article published on September 1, 2010

Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction.

scientific article

Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor

scientific article published on April 2007

Human progenitor cells with high aldehyde dehydrogenase activity efficiently engraft into damaged liver in a novel model.

scientific article

Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo.

scientific article published on 11 May 2015

Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells

scientific article

Immunodeficient mice as models of human hematopoietic stem cell engraftment.

scientific article

Immunodeficient mouse models to study human stem cell-mediated tissue repair

scientific article published in January 2008

Improving mesenchymal stem/stromal cell potency and survival: Proceedings from the International Society of Cell Therapy (ISCT) MSC preconference held in May 2018, Palais des Congrès de Montréal, Organized by the ISCT MSC Scientific Committee

scientific article published on 15 February 2020

In vitro purging of human rhabdomyosarcoma cells using 4-hydroperoxycyclophosphamide

scientific article

In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models

scientific article

Inclusion of IL-3 during retrovirally-mediated transduction on stromal support does not increase the extent of gene transfer into long-term engrafting human hematopoietic progenitors.

scientific article

Induction of human embryonic and induced pluripotent stem cells into urothelium

scientific article

Inosculation of blood vessels allows early perfusion and vitality of bladder grafts--implications for bioengineered bladder wall

scientific article published on 22 April 2015

Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway

scientific article published on October 2013

Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration.

scientific article

Intravitreal autologous bone marrow CD34+ cell therapy for ischemic and degenerative retinal disorders: preliminary phase 1 clinical trial findings

scientific article

Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

scientific article published on 17 June 2015

Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivo

scientific article

Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease

scientific article published on 24 April 2008

Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model

scientific article published on January 1997

Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury

scientific article published on 23 February 2012

Long-term persistence of donor nuclei in a Duchenne muscular dystrophy patient receiving bone marrow transplantation

scientific article

Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells

scientific article

Lysophosphatidic acid enhances stromal cell-directed angiogenesis

scientific article

Mechanisms of modulation and differentiation in mesenchymal stem/stromal cells

scientific article published on 01 January 2021

Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols.

scientific article published on 24 July 2015

Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors.

scientific article published on September 2010

Mesenchymal stem cells for the treatment of neurodegenerative disease.

scientific article

Mesenchymal stem cells for trinucleotide repeat disorders

scientific article published on January 2013

Mesenchymal stem/stromal cells genetically engineered to produce vascular endothelial growth factor for revascularization in wound healing and ischemic conditions

scientific article published on 01 November 2018

Migration of mesenchymal stem cells to heart allografts during chronic rejection

scientific article published on March 2003

Molecular mechanism of transforming growth factor β–mediated cell-cycle modulation in primary human CD34+ progenitors ⬇️

scientific article published on January 15, 2002

Multidrug resistance gene expression in pediatric primitive neuroectodermal tumors of the central nervous system

scientific article published in March 1992

Natural killer cell subsets differentially reject embryonic stem cells based on licensing

scientific article

New advances in understanding stem cell fate and function

scientific article published in February 2015

Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate.

scientific article published on 22 July 2016

Novel murine xenograft model for the evaluation of stem cell therapy for profound dysphagia.

scientific article published on 23 May 2017

Novel targeted therapy for neuroblastoma: silencing the MXD3 gene using siRNA.

scientific article

Now More Than Ever: The Importance of Reporting Evidence-Based Science

scientific article published on 01 January 2019

P3C-2 Ultrasound Energy Rapidly Labels Stem/Progenitor Cells with Nanoparticle Beacons without Disrupting Membrane Integrity

Phenotypic comparison of extrathymic human bone-marrow-derived T cells with thymic-selected T cells recovered from different tissues

scientific article published on 01 September 2001

Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia

scientific article published on 24 August 2016

Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy

scientific article

Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation

scientific article published on 26 March 2019

Protective Effect of Intravitreal Administration of Exosomes Derived from Mesenchymal Stem Cells on Retinal Ischemia.

scientific article

Recent advances in hematopoietic stem cell biology

scientific article

Reduction in levels of the cyclin-dependent kinase inhibitor p27 kip-1 coupled with transforming growth factor β neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells ⬇️

scientific article published on October 27, 1998

Research Leads to Approved Therapies in the New Era of Living Medicine

scientific article

Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation

scientific article

Retroviral vector-mediated gene transfer into primitive human hematopoietic progenitor cells: effects of mast cell growth factor (MGF) combined with other cytokines

scientific article published in October 1992

Retroviral-mediated transduction and clonal integration analysis of human hematopoietic stem and progenitor cells

scientific article published in January 2002

Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow

scientific article published on August 1992

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity.

scientific article published on 26 March 2009

Reversibility of CD34 expression on human hematopoietic stem cells that retain the capacity for secondary reconstitution

scientific article published on 25 July 2002

Reversing bone loss by directing mesenchymal stem cells to bone.

scientific article published on September 2013

Role of miRNAs in neuronal differentiation from human embryonic stem cell-derived neural stem cells

scientific article

Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells

scientific article published on March 2015

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

scientific article published on 3 November 2005

Self-inactivating lentiviral vectors resist proviral methylation but do not confer position-independent expression in hematopoietic stem cells

scientific article

Signaling defects in iPSC-derived fragile X premutation neurons

scientific article

Specific transduction of HIV-susceptible cells for CCR5 knockdown and resistance to HIV infection: a novel method for targeted gene therapy and intracellular immunization.

scientific article published on October 2009

Spotlight on hematopoietic stem cells: looking beyond dogma. Introduction

scientific article published on 01 November 2001

Stem Cells' position statement on hESC research

scientific article published on 01 September 2010

Stem cells in canine spinal cord injury--promise for regenerative therapy in a large animal model of human disease.

scientific article

Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors

scientific article published on 01 May 1994

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.

scientific article published on July 1998

Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia.

scientific article

The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors

scientific article published on March 2002

The Complex Ethics of First In Human Stem Cell Clinical Trials

scientific article published on January 2012

The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation

scientific article

The age of immunotherapy-Celebrating STEM CELLS' contribution to understanding mechanisms of immune system development and modulation

scientific article published on 01 January 2020

The number and generative capacity of human B lymphocyte progenitors, measured in vitro and in vivo, is higher in umbilical cord blood than in adult or pediatric bone marrow

scientific article published on 01 December 1999

The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance

scientific article published on 30 July 2012

The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long-term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease.

scientific article published in October 1995

Toward gene therapy for Gaucher disease

scientific article published on January 1991

Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer

scientific article published on January 1994

Use of the bnx/hu xenograft model of human hematopoiesis to optimize methods for retroviral-mediated stem cell transduction (Review).

scientific article published in January 1998

Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity.

scientific article

shRNA-mediated decreases in c-Met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair

scientific article

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