List of works - Stephen Anthony Cusack

Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

scientific article

Dynamical transition of myoglobin revealed by inelastic neutron scattering

scientific article

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

scientific article

A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 A.

scientific article

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

scientific article

The structural basis for cap binding by influenza virus polymerase subunit PB2

scientific article

The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser)

scientific article

Structure of influenza A polymerase bound to the viral RNA promoter

scientific article published on 19 November 2014

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

scientific article

The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution

scientific article

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

scientific article

A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein

scientific article

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

scientific article

Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription

scientific article published on September 16, 2010

The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue

scientific article

Structure of influenza virus RNP. I. Influenza virus nucleoprotein melts secondary structure in panhandle RNA and exposes the bases to the solvent

scientific article (publication date: July 1994)

The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid

scientific article

Head-to-tail dimers and interdomain flexibility revealed by the crystal structure of HIV-1 capsid protein (p24) complexed with a monoclonal antibody Fab.

scientific article published on March 1999

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

scientific article (publication date: April 2004)

Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase

scientific article (publication date: April 2003)

Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex

scientific article

The structure of the human adenovirus 2 penton

scientific article published on January 2005

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit

scientific article

Class I tyrosyl-tRNA synthetase has a class II mode of cognate tRNA recognition

scientific article

Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion

scientific article (publication date: June 2003)

Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites

scientific article published on July 2004

Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms

scientific article

A quasi-atomic model of human adenovirus type 5 capsid

scientific article published on 21 April 2005

The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

scientific article

Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution

scientific article

Structural insights into the Slit-Robo complex

scientific article

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

scientific article

Structure and assembly of the Alu domain of the mammalian signal recognition particle

scientific article

Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter.

scientific article published on 21 May 2015

RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts

scientific article

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor

scientific article

Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

scientific article

The crystal structures of T. thermophilus lysyl-tRNA synthetase complexed with E. coli tRNA(Lys) and a T. thermophilus tRNA(Lys) transcript: anticodon recognition and conformational changes upon binding of a lysyl-adenylate analogue

scientific article

Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase

scientific article

CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing

scientific article published on 24 November 2013

A structure-based model of RIG-I activation

scientific article

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains

scientific article published on 16 December 2015

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

scientific article

Crystal structure of the human nuclear cap binding complex

scientific article

A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase

scientific article

Towards an atomic resolution understanding of the influenza virus replication machinery

scientific article published on 12 January 2010

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

scientific article

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

scientific article

Dynamic instability of liquidlike motions in a globular protein observed by inelastic neutron scattering

scientific article published in Physical Review Letters

Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA

scientific article

List of works by Stephen Anthony Cusack

Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

Dynamical transition of myoglobin revealed by inelastic neutron scattering

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 A.

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

The structural basis for cap binding by influenza virus polymerase subunit PB2

The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser)

Structure of influenza A polymerase bound to the viral RNA promoter

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription

The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue

Structure of influenza virus RNP. I. Influenza virus nucleoprotein melts secondary structure in panhandle RNA and exposes the bases to the solvent

The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid

Head-to-tail dimers and interdomain flexibility revealed by the crystal structure of HIV-1 capsid protein (p24) complexed with a monoclonal antibody Fab.

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase

Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex

The structure of the human adenovirus 2 penton

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit

Class I tyrosyl-tRNA synthetase has a class II mode of cognate tRNA recognition

Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion

Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites

Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms

A quasi-atomic model of human adenovirus type 5 capsid

The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution

Structural insights into the Slit-Robo complex

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

Structure and assembly of the Alu domain of the mammalian signal recognition particle

Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter.

RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor

Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

The crystal structures of T. thermophilus lysyl-tRNA synthetase complexed with E. coli tRNA(Lys) and a T. thermophilus tRNA(Lys) transcript: anticodon recognition and conformational changes upon binding of a lysyl-adenylate analogue

Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase

CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing

A structure-based model of RIG-I activation

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

Crystal structure of the human nuclear cap binding complex

A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase

Towards an atomic resolution understanding of the influenza virus replication machinery

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

Dynamic instability of liquidlike motions in a globular protein observed by inelastic neutron scattering

Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA