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List of works by Susan C. Baker

1876. A Hepacivirus-Like Protein Is Targeted by the Antibody Response to Kawasaki Disease (KD)

scientific article published on 23 October 2019

A Protein Epitope Targeted by the Antibody Response to Kawasaki Disease

scientific article published on 13 February 2020

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses

scientific article

A new cistron in the murine hepatitis virus replicase gene

scientific article published on 28 July 2010

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

scientific article

A study of cardiovascular miRNA biomarkers for Kawasaki disease.

scientific article

Allograft Inflammatory Factor-1 Links T-Cell Activation, Interferon Response, and Macrophage Activation in Chronic Kawasaki Disease Arteritis

scientific article published on 15 May 2017

An "Old" protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses

scientific article published on 4 January 2018

Analysis of Coronavirus Temperature-Sensitive Mutants Reveals an Interplay between the Macrodomain and Papain-Like Protease Impacting Replication and Pathogenesis

scientific article published on 15 June 2019

Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

scientific article published on 28 August 2013

Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus

scientific article

Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors

scientific article

Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines

scientific article published on 08 September 2018

Cloning the arterial IgA antibody response during acute Kawasaki disease

scientific article published on 01 December 2005

Colocalization and membrane association of murine hepatitis virus gene 1 products and De novo-synthesized viral RNA in infected cells.

scientific article

Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions.

scientific article published on April 2014

Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses

scientific article published on 15 April 2019

Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages

scientific article published on 18 March 2020

Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression

scientific article

Coronavirus Papain-like Peptidases

Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling ⬇️

scientific article published on January 1, 2012

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

scientific article published on 20 March 2020

Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

scientific article published on 8 May 2017

Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance

scientific article

Cytoplasmic inclusion bodies are detected by synthetic antibody in ciliated bronchial epithelium during acute Kawasaki disease

scientific article published on 17 October 2005

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

scientific article

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

scientific article published on 28 August 2008

Detection of antigen in bronchial epithelium and macrophages in acute Kawasaki disease by use of synthetic antibody

scientific article published on 16 July 2004

Detection of nonstructural protein 6 in murine coronavirus-infected cells and analysis of the transmembrane topology by using bioinformatics and molecular approaches

scientific article published on 22 April 2009

Deubiquitinating Activity of the SARS-CoV Papain-Like Protease

scientific article published on 01 January 2006

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

scientific article

Developing bioinformatic resources for coronaviruses

scientific article published on January 2006

Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026

scientific article published on 13 November 2020

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

scientific article published on 05 September 2019

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus [...]

scientific article

Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro

scientific article published on 01 September 2020

Eosinophilic Esophagitis: the Potential Role of Biologics in its Treatment

scientific article published on 07 June 2019

Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

scientific article published on 29 March 2007

Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus

scientific article published on 30 August 2019

Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing ⬇️

scientific article published on November 21, 2012

Human airway epithelial cell culture to identify new respiratory viruses: coronavirus NL63 as a model

scientific article published on 05 December 2008

Human coronavirus NL63 is not detected in the respiratory tracts of children with acute Kawasaki disease

scientific article

Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

scientific article published on December 2004

Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2.

scientific article

Inactivating Three Interferon Antagonists Attenuates Pathogenesis of an Enteric Coronavirus

scientific article published on 17 June 2020

Integrins α4 and αM, collagen1A1, and matrix metalloproteinase 7 are upregulated in acute Kawasaki disease vasculopathy ⬇️

scientific article published on December 7, 2012

Introduction to Virology special issue featuring nidovirus research

scientific article published on 01 April 2018

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

scientific article published on 22 December 2013

Membrane topology of murine coronavirus replicase nonstructural protein 3.

scientific article published on 12 January 2007

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

scientific article

Morphogenesis of Coronavirus HCoV-NL63 in Cell Culture: A Transmission Electron Microscopic Study

scientific article published on January 2008

Mouse hepatitis virus infection activates the Ire1/XBP1 pathway of the unfolded protein response

scientific article published in January 2006

Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis

scientific article

Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive ⬇️

scientific article published on October 23, 2012

Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles

scientific article published on 4 March 2008

Nidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activities

scientific article

Periostin is upregulated in coronary arteriopathy in Kawasaki disease and is a potential diagnostic biomarker.

scientific article

Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [F]-Flutemetamol PET Scan Result

scientific article published on 11 December 2018

Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy.

scientific article published on February 2007

Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63

scientific article published on 28 March 2007

RNA replication of mouse hepatitis virus takes place at double-membrane vesicles

scientific article

RNA-containing cytoplasmic inclusion bodies in ciliated bronchial epithelium months to years after acute Kawasaki disease

scientific article

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

scientific article published on 30 August 2007

Relationships between coarse woody debris habitat quality and forest maturity attributes

scientific article published on 01 September 2019

Renilla luciferase as a reporter to assess SARS-CoV mRNA transcription regulation and efficacy of anti-SARS-CoV agents

scientific article published on 01 January 2006

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

scientific article

SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway

scientific article published on 28 October 2020

Searching for the cause of Kawasaki disease--cytoplasmic inclusion bodies provide new insight.

scientific article

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme

scholarly article

Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group

scientific article published on 11 February 2020

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

scientific article

Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus

scientific article published on 18 March 2020

Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus

scientific article published on 26 September 2019

Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease

scientific article published in August 2009

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

scientific article

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species

scientific article published on 24 September 2018

The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase ⬇️

scientific article published on April 17, 2013

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

scientific article published on December 2005

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

scientific article published on 2 March 2020

The transcriptional profile of coronary arteritis in Kawasaki disease

scientific article

Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study ⬇️

scientific article published on June 18, 2012

Ultrastructural, Immunofluorescence, and RNA Evidence Support the Hypothesis of a “New” Virus Associated With Kawasaki Disease ⬇️

scientific article published on April 1, 2011

Use of Centers for Disease Control and Prevention Gravid Trap in Catch Basins: Proof-Of-Concept Trials

scientific article published on June 2015

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

scientific article published on 01 January 2020

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

scientific article

X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions

scientific article

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

scientific article published on 12 January 2017

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