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List of works by Klaus Warnatz

14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency

scientific article published on 16 August 2017

15-Deoxyspergualin in patients with refractory ANCA-associated systemic vasculitis: a six-month open-label trial to evaluate safety and efficacy

scientific article published in February 2003

2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

scientific article published on 14 August 2019

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.

scientific article published on 7 January 2014

A homozygous CARD9 mutation in a family with susceptibility to fungal infections

scientific article

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

scientific article published on 19 June 2020

A new CD21low B cell population in the peripheral blood of patients with SLE.

scientific article published in November 2004

A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis.

scientific article

Advances in the Care of Primary Immunodeficiencies (PIDs): from Birth to Adulthood

scientific article

Analysis of bulk and virus-specific CD8+ T cells reveals advanced differentiation of CD8+ T cells in patients with common variable immunodeficiency ⬇️

scientific article published on August 5, 2011

Analysis of specific IgG titers against tick-borne encephalitis in patients with primary antibody deficiency under immunoglobulin substitution therapy: impact of plasma donor origin

scientific article

Anti-IgA antibodies in common variable immunodeficiency (CVID): diagnostic workup and therapeutic strategy

scientific article published on 28 November 2006

Assessing the Functional Relevance of Variants in the () in a Cohort of Patients With Primary Immunodeficiency ⬇️

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells

scientific article published on 20 April 2015

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases

scientific article

Autoimmune lymphoproliferative syndrome-like disease in patients with LRBA mutation

scientific article published on 27 April 2015

Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial ⬇️

scientific article published on 25 June 2014

Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis

scientific article published on 22 March 2017

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

scientific article

B cell depletion by Rituximab severely reduces immunoglobulin levels in patients with ANCA-associated vasculitis previously treated with cyclophosphamide

scientific article published on 23 November 2011

B cell homeostasis is disturbed by immunosuppressive therapies in patients with ANCA-associated vasculitides ⬇️

scientific article published on June 6, 2013

B cell receptor-mediated calcium signaling is impaired in B lymphocytes of type Ia patients with common variable immunodeficiency

scientific article published on 21 May 2010

B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans.

scholarly article

B-cell signaling in persistent polyclonal B lymphocytosis (PPBL).

scientific article

Bronchoalveolar lavage cytology resembles sarcoidosis in a subgroup of granulomatous CVID

scientific article published on 01 March 2014

Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.

scientific article published on 9 June 2011

CCL18 -- potential biomarker of fibroinflammatory activity in chronic periaortitis.

scientific article

CD21low B cells in common variable immunodeficiency do not show defects in receptor editing, but resemble tissue-like memory B cells ⬇️

scientific article published on November 4, 2010

Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency

scientific article published on 10 December 2021

Characterization of the clinical and immunological phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations

scientific article published on 09 April 2020

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells.

scholarly article

Classification of common variable immunodeficiencies using flow cytometry and a memory B-cell functionality assay

scientific article published on 10 August 2014

Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in

scientific article published on 19 March 2019

Clinical picture and treatment of 2212 patients with common variable immunodeficiency

scientific article published on 28 February 2014

Common variable immunodeficiency (CVID): exploring the multiple dimensions of a heterogeneous disease.

scientific article published on 02 February 2012

Common variable immunodeficiency - an update ⬇️

scientific article published on September 24, 2012

Common variable immunodeficiency at the end of a prospering decade: towards novel gene defects and beyond ⬇️

scientific article published on December 1, 2010

Common variable immunodeficiency-associated granulomatous and interstitial lung disease

scientific article

Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group

scientific article published on 01 February 2019

Correction: Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT.

scientific article published on June 2017

Corrigendum: Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency

scientific article published on 28 June 2019

Current Understanding and Future Research Priorities in Malignancy Associated With Inborn Errors of Immunity and DNA Repair Disorders: The Perspective of an Interdisciplinary Working Group

scientific article published on 12 December 2018

Cytokines in common variable immunodeficiency as signs of immune dysregulation and potential therapeutic targets - a review of the current knowledge

scientific article published on 15 May 2014

Deep intronic mis-splicing mutation in JAK3 gene underlies T-B+NK- severe combined immunodeficiency phenotype

scientific article

Deficiencies in the CD19 complex

scientific article published on 31 July 2018

Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects

scientific article published in February 2013

Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients

scientific article published in October 2005

Dependence of immunoglobulin class switch recombination in B cells on vesicular release of ATP and CD73 ectonucleotidase activity

scientific article published on 13 June 2013

Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry. ⬇️

scientific article published on 16 March 2018

Dissecting CXCR5+ T cell populations--on the quest for a better understanding of B cell help during T dependent antibody responses

scientific article published on 01 July 2006

Disseminated tuberculosis in a patient with idiopathic CD4+ lymphocytopenia

scientific article published on 11 August 2009

Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity

scientific article published on 23 November 2019

Disturbed canonical nuclear factor of κ light chain signaling in B cells of patients with common variable immunodeficiency

scientific article published on 14 June 2016

Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT.

scientific article published on 30 May 2016

Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency

scientific article

Efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases: a systematic literature review for the 2019 update of EULAR recommendations

scientific article published on 09 September 2019

Elevated serum osteopontin levels in idiopathic retroperitoneal fibrosis

scientific article published on September 1, 2012

Enteroviral Infection in a Patient with BLNK Adaptor Protein Deficiency.

scientific article published on 17 April 2015

Evaluating laboratory criteria for combined immunodeficiency in adult patients diagnosed with common variable immunodeficiency

scientific article published on 17 April 2019

Exhausted phenotype of follicular CD8 T cells in CVID

scientific article published on 10 March 2020

Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia

scientific article

Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency.

scientific article published on 14 November 2014

Fatal adult-onset antibody deficiency syndrome in a patient with cartilage hair hypoplasia

scientific article published on 09 June 2010

Fatal ulcerative enteritis of the small intestine in a patient with ulcerative colitis treated with vedolizumab

scientific article published on 27 June 2017

Flowcytometric phenotyping of common variable immunodeficiency

scientific article published on 01 September 2008

Follicular Helper T Cells in DiGeorge Syndrome

scientific article published on 23 July 2018

Generalized verrucosis and HPV-3 susceptibility associated with CD4 T-cell lymphopenia caused by inherited human interleukin-7 deficiency

scientific article published on 01 June 2015

Genetic CD21 deficiency is associated with hypogammaglobulinemia

scientific article published on 27 October 2011

Germline deletion of CIN85 in humans with X chromosome-linked antibody deficiency

scientific article published on 10 April 2018

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency.

scientific article

Hepatitis E and jaundice in an HIV-positive pregnant woman

scientific article published on 01 April 2008

High SYK Expression Drives Constitutive Activation of CD21low B Cells.

scientific article published on 3 May 2017

High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.

scientific article

High-resolution CT imaging of the lung for patients with primary Sjögren’s syndrome

scientific article published on 01 November 2004

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

scientific article (publication date: March 2003)

Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency

scientific article published on 29 December 2005

Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

scientific article

ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells

scientific article published in October 2006

IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.

scientific article published on 17 March 2017

Idiopathic CD4 lymphocytopenia

scientific article (publication date: July 2006)

IgG4-related disease in autoimmune lymphoproliferative syndrome

scientific article published on 3 May 2017

Ill-defined germinal centers and severely reduced plasma cells are histological hallmarks of lymphadenopathy in patients with common variable immunodeficiency.

scientific article published on 2 May 2014

Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group

scientific article published on 13 December 2018

Immunodeficiency in adults a practical guide for the allergist

scientific article

Immunologist's Perspectives on Assessment and Management of Lung Disease in CVID: a Survey of the Membership of the Clinical Immunology Society and the European Society for Immunodeficiencies

scientific article published on 08 April 2018

Impact of rituximab on immunoglobulin concentrations and B cell numbers after cyclophosphamide treatment in patients with ANCA-associated vasculitides

scientific article

Impaired polysaccharide responsiveness without agammaglobulinaemia in three patients with hypomorphic mutations in Bruton Tyrosine Kinase-No detection by newborn screening for primary immunodeficiencies

scientific article published on 30 October 2019

Incidence and prevalence of vaccine preventable infections in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD): a systemic literature review informing the 2019 update of the EULAR recommendations for vaccination in adult patien

scientific article published on 19 September 2019

Increase of circulating α4β7+ conventional memory CD4 and regulatory T cells in patients with common variable immunodeficiency (CVID).

scientific article

Increased Risk for Malignancies in 131 Affected Mutation Carriers

scientific article published on 10 September 2018

International Consensus Document (ICON): Common Variable Immunodeficiency Disorders

scientific article

Interstitial lung disease in primary immunodeficiency: towards a brighter future

scientific article published on 03 April 2020

Is It Safe to Switch From Intravenous Immunoglobulin to Subcutaneous Immunoglobulin in Patients With Common Variable Immunodeficiency and Autoimmune Thrombocytopenia?

Late-onset hemophagocytic lymphohistiocytosis (HLH) in an adult female with Griscelli syndrome type 2 (GS2).

scientific article published on 30 December 2014

Molecules involved in T-B co-stimulation and B cell homeostasis: possible targets for an immunological intervention in autoimmunity

scientific article

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

scientific article published on 07 July 2015

Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency

scientific article

NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases

scientific article published on 23 September 2013

Naive- and Memory-like CD21low B Cell Subsets Share Core Phenotypic and Signaling Characteristics in Systemic Autoimmune Disorders

scientific article published on 09 September 2020

Non permissive bone marrow environment impairs early B-cell development in common variable immunodeficiency

scientific article published on 10 March 2020

Novel Patient with Late-Onset Familial Hemophagocytic Lymphohistiocytosis with STXBP2 Mutations Presenting with Autoimmune Hepatitis, Neurological Manifestations and Infections Associated with Hypogammaglobulinemia

scientific article published on 10 December 2014

Outcome of allogeneic stem cell transplantation in adults with common variable immunodeficiency

scientific article published on 17 September 2011

Pathogenesis of autoimmunity in common variable immunodeficiency ⬇️

scientific article published on July 18, 2012

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects

scientific article published on 04 May 2018

Phenotypic and Functional Comparison of Class Switch Recombination Deficiencies with a Subgroup of Common Variable Immunodeficiencies

scientific article published on 02 August 2016

Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation.

scientific article published on 21 September 2017

Preserved cellular immunity upon influenza vaccination in most patients with common variable immunodeficiency

scientific article published on 21 April 2020

Prolonged treatment of refractory Wegener's granulomatosis with 15-deoxyspergualin: an open study in seven patients

scientific article published on 12 April 2005

Protein Kinase C δ: a Gatekeeper of Immune Homeostasis

scientific article

Recurrence of persistent polyclonal B lymphocytosis (PPBL) after rituximab treatment

scientific article published on 01 February 2015

Reply

Rescue of Cytokine Storm Due to HLH by Hemoadsorption in a CTLA4-Deficient Patient

scientific article

Review: Cryptococcosis in HIV-negative immunodeficiency

scientific article published on June 2008

STAT3 gain-of-function mutations associated with autoimmune lymphoproliferative syndrome like disease deregulate lymphocyte apoptosis and can be targeted by BH3 mimetic compounds

scientific article published in June 2017

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

scientific article published on 4 May 2015

Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood

scientific article published on 10 May 2017

Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency

scientific article

Severe deficiency of switched memory B cells (CD27(+)IgM(-)IgD(-)) in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease

scientific article published on 01 March 2002

Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count

scientific article published on 12 February 2019

Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

scientific article published on 01 April 2022

Sinonasal computed tomography in patients with Wegener's granulomatosis

scientific article published in January 2006

Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors

scientific article

Soluble CD90 as a potential marker of pulmonary involvement in systemic sclerosis

scientific article published in February 2013

Spuriously low IgG levels in lupus-associated mixed cryoglobulinaemia type II complicated by iatrogenic immunoglobulin-induced immune complex vasculitis

scientific article published on 01 November 2012

Structural Noninfectious Manifestations of the Central Nervous System in Common Variable Immunodeficiency Disorders

scientific article published on 16 December 2019

T and B lymphocyte abnormalities in bone marrow biopsies of common variable immunodeficiency.

scientific article published on 16 May 2011

T+ NK+ IL-2 Receptor γ Chain Mutation: a Challenging Diagnosis of Atypical Severe Combined Immunodeficiency

scientific article published on 01 May 2018

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes

Tackling the heterogeneity of CVID.

scientific article

Telomere-dependent replicative senescence of B and T cells from patients with type 1a common variable immunodeficiency

scientific article published on 02 February 2011

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency

scientific article

The EUROclass trial: defining subgroups in common variable immunodeficiency.

scientific article published on 26 September 2007

The German National Registry of Primary Immunodeficiencies (2012-2017)

scientific article published on 19 July 2019

The TH1 phenotype of follicular helper T cells indicates an IFN-γ-associated immune dysregulation in patients with CD21low common variable immunodeficiency.

scientific article published on 26 May 2017

The autoimmune conundrum in common variable immunodeficiency disorders

scientific article

The crossroads of autoimmunity and immunodeficiency: Lessons from polygenic traits and monogenic defects.

scientific article

The immunological synapse for B-cell memory: the role of the ICOS and its ligand for the longevity of humoral immunity ⬇️

scientific article published on December 1, 2003

The role of HLA DQ2 and DQ8 in dissecting celiac-like disease in common variable immunodeficiency.

scientific article published on 23 April 2013

Treatment and management of primary antibody deficiency: German interdisciplinary evidence-based consensus guideline

scientific article published on 26 August 2020

Treatment of Progressive Multifocal Leukoencephalopathy with Pembrolizumab

scientific article published on 10 April 2019

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.

scientific article published on 11 July 2016

[Development of an Intervention to Enhance Health Literacy of Patients with Common Variable Immunodeficiency (CVID)]

scientific article published on 15 October 2019

[Primary Immunodeficiency in Adults]

scientific article published on 31 May 2017

β2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system.

scientific article published on 19 February 2015

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