List of works - Susan Coort

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

scientific article

A bioinformatics workflow to decipher transcriptomic data from vitamin D studies

scientific article published on 01 February 2019

A network biology workflow to study transcriptomics data of the diabetic liver

scientific article

Adipocyte abundances of CES1, CRYAB, ENO1 and GANAB are modified in-vitro by glucose restriction and are associated with cellular remodelling during weight regain

scientific article published on 01 December 2019

Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention

scientific article (publication date: 8 February 2011)

Bioinformatics for the NuGO proof of principle study: analysis of gene expression in muscle of ApoE3*Leiden mice on a high-fat diet using PathVisio

scientific article (publication date: December 2008)

Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus-A Co-expression Network Based Analysis

Blunted nutrient-response pathways in adipose tissue following high fat meals in men with metabolic syndrome: A randomized postprandial transcriptomic study

scientific article published on 27 August 2020

CD11c<sup>-</sup>MHC2<sup>low</sup> Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue

scientific article published on 01 April 2020

COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms ⬇️

journal article from 'Molecular Systems Biology' published in 2021

Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

scientific article (publication date: September 2007)

Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters

scientific article (publication date: 19 September 2006)

Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

scientific journal article

CyTargetLinker app update: A flexible solution for network extension in Cytoscape

scientific article published on 14 June 2018

CyTargetLinker app update: A flexible solution for network extension in Cytoscape

CyTargetLinker: a cytoscape app to integrate regulatory interactions in network analysis

scientific article (publication date: 2013)

Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of neurodegenerative diseases

Dipyridamole alters cardiac substrate preference by inducing translocation of FAT/CD36, but not that of GLUT4.

scientific article published in March 2004

Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats

scientific article

Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats

scientific article (publication date: 25 June 2004)

Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage

scientific article (publication date: 3 November 2010)

Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.

scientific article published on April 2009

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon

scientific article (publication date: December 2009)

From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results

scientific article published in 2018

Identification of Biological Pathways Contributing to Marbling in Skeletal Muscle to Improve Beef Cattle Breeding

scientific article published on 01 January 2019

Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

scientific article published on 11 December 2019

Identification of platelet function defects by multi-parameter assessment of thrombus formation

scientific article

Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK.

scientific article published on 26 November 2007

Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats

scientific journal article

Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm

scientific article

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

article

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

scientific article published on 25 March 2019

Integrative network-based analysis of mRNA and microRNA expression in 1,25-dihydroxyvitamin D3-treated cancer cells

scientific article published on 15 August 2015

Marginal selenium deficiency down-regulates inflammation-related genes in splenic leukocytes of the mouse

article

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

scientific article

Network Analysis of Genome-Wide Association Studies for Chronic Obstructive Pulmonary Disease in the Context of Biological Pathways

scientific article published on 01 December 2019

New insights in Rett syndrome using pathway analysis for transcriptomics data

scientific article

Pathway analysis of transcriptomic data shows immunometabolic effects of vitamin D.

scientific article published on 12 December 2017

Pathway enrichment based on text mining and its validation on carotenoid and vitamin A metabolism

scientific article

Prader-Willi Syndrome and Angelman Syndrome: Visualisation of the molecular pathways for two chromosomal disorders.

scientific article published on 9 February 2018

Presenting and exploring biological pathways with PathVisio

scientific article

Prolonged AMPK Activation Increases the Expression of Fatty Acid Transporters in Cardiac Myocytes and Perfused Hearts

scientific article (publication date: 19 May 2006)

Providing gene-to-variant and variant-to-gene database identifier mappings to use with BridgeDb mapping services

Reactome from a WikiPathways Perspective

scientific article (publication date: May 2016)

Regulation of FAT/CD36-mediated long-chain fatty acid uptake by cardiac muscle ⬇️

PhD thesis of Susan Coort

Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters

scientific article (publication date: 10 February 2004)

Regulation of fatty acid transport by fatty acid translocase/CD36

scientific article (publication date: May 2004)

Rett syndrome - biological pathways leading from MECP2 to disorder phenotypes

scientific article (publication date: 25 November 2016)

Role of 1α,25-Dihydroxyvitamin D 3 in Adipogenesis of SGBS Cells: New Insights into Human Preadipocyte Proliferation

Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures

scientific article

Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes

scientific article published in May 2004

Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake

scientific article (publication date: 2002)

Ten simple rules for creating reusable pathway models for computational analysis and visualization

scientific article published on 19 August 2021

The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

scientific article (publication date: 26 November 2008)

The future of food and nutrition in ELIXIR

scientific article published on 25 August 2022

The public road to high-quality curated biological pathways

scientific article published in October 2008

The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR

scientific journal article

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

scientific article

Transcriptomic analysis of vitamin D responses in uterine and peripheral NK cells

scientific article published on 01 August 2019

Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis

publication published on 19 July 2021

Uncoupling protein 3 as a mitochondrial fatty acid anion exporter

scientific article (publication date: December 2003)

Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways

scientific article

WikiPathways 2024: next generation pathway database

scientific article published on 6 November 2023

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research

scientific article published on 10 November 2017

WikiPathways: capturing the full diversity of pathway knowledge

Research paper from 2016 about the WikiPathways database.

WikiPathways: connecting communities ⬇️

scientific article published on 19 November 2020

List of works by Susan Coort

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

A bioinformatics workflow to decipher transcriptomic data from vitamin D studies

A network biology workflow to study transcriptomics data of the diabetic liver

Adipocyte abundances of CES1, CRYAB, ENO1 and GANAB are modified in-vitro by glucose restriction and are associated with cellular remodelling during weight regain

Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention

Bioinformatics for the NuGO proof of principle study: analysis of gene expression in muscle of ApoE3*Leiden mice on a high-fat diet using PathVisio

Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus-A Co-expression Network Based Analysis

Blunted nutrient-response pathways in adipose tissue following high fat meals in men with metabolic syndrome: A randomized postprandial transcriptomic study

CD11c<sup>-</sup>MHC2<sup>low</sup> Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue

COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms ⬇️

Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters

Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

CyTargetLinker app update: A flexible solution for network extension in Cytoscape

CyTargetLinker app update: A flexible solution for network extension in Cytoscape

CyTargetLinker: a cytoscape app to integrate regulatory interactions in network analysis

Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of neurodegenerative diseases

Dipyridamole alters cardiac substrate preference by inducing translocation of FAT/CD36, but not that of GLUT4.

Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats

Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats

Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage

Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon

From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results

Identification of Biological Pathways Contributing to Marbling in Skeletal Muscle to Improve Beef Cattle Breeding

Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK.

Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats

Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

Integrative network-based analysis of mRNA and microRNA expression in 1,25-dihydroxyvitamin D3-treated cancer cells

Marginal selenium deficiency down-regulates inflammation-related genes in splenic leukocytes of the mouse

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

Network Analysis of Genome-Wide Association Studies for Chronic Obstructive Pulmonary Disease in the Context of Biological Pathways

New insights in Rett syndrome using pathway analysis for transcriptomics data

Pathway analysis of transcriptomic data shows immunometabolic effects of vitamin D.

Pathway enrichment based on text mining and its validation on carotenoid and vitamin A metabolism

Prader-Willi Syndrome and Angelman Syndrome: Visualisation of the molecular pathways for two chromosomal disorders.

Presenting and exploring biological pathways with PathVisio

Prolonged AMPK Activation Increases the Expression of Fatty Acid Transporters in Cardiac Myocytes and Perfused Hearts

Providing gene-to-variant and variant-to-gene database identifier mappings to use with BridgeDb mapping services

Reactome from a WikiPathways Perspective

Regulation of FAT/CD36-mediated long-chain fatty acid uptake by cardiac muscle ⬇️

Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters

Regulation of fatty acid transport by fatty acid translocase/CD36

Rett syndrome - biological pathways leading from MECP2 to disorder phenotypes

Role of 1α,25-Dihydroxyvitamin D 3 in Adipogenesis of SGBS Cells: New Insights into Human Preadipocyte Proliferation

Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures

Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes

Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake

Ten simple rules for creating reusable pathway models for computational analysis and visualization

The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

The future of food and nutrition in ELIXIR

The public road to high-quality curated biological pathways

The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

Transcriptomic analysis of vitamin D responses in uterine and peripheral NK cells

Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis

Uncoupling protein 3 as a mitochondrial fatty acid anion exporter

Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways

WikiPathways 2024: next generation pathway database

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research

WikiPathways: capturing the full diversity of pathway knowledge

WikiPathways: connecting communities ⬇️