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List of works by Douglas R. Green

'Tit-for-tat' in cell biology

scientific article published in February 2011

A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc.

scientific article published in October 2000

A BH3 Mimetic for Killing Cancer Cells

scientific article published in June 2016

A Distinct Lung-Interstitium-Resident Memory CD8(+) T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection

scientific article published on 03 August 2016

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

scientific article published on September 2017

A matter of life and death

scientific article published on 01 February 2002

A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid

scientific article

A survivor hits the breaks

scientific article published on February 2008

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

scientific article published on 27 October 2011

APOPTOSIS: A Myc-Induced Apoptosis Pathway Surfaces

scientific article published on 01 November 1997

Abrogation of oral tolerance by contrasuppressor T cells suggests the presence of regulatory T-cell networks in the mucosal immune system.

scientific article published in April 1986

Acridine Orange/Ethidium Bromide (AO/EB) Staining to Detect Apoptosis

scientific article published on 01 August 2006

Activation-induced apoptosis in lymphocytes.

scientific article published on June 1994

Activation-induced cell death in T cells

scientific article

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

scientific article published on July 2012

An Element of Life

scientific article published in January 2018

Analysis of DNA Fragmentation Using Agarose Gel Electrophoresis

scientific article published on 01 June 2006

Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts

scientific article published on 01 August 1999

And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis

scientific article

Anthracyclines induce DNA damage response-mediated protection against severe sepsis.

scientific article published on 31 October 2013

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

scientific article

Antigen-Specific Immunoregulatory Activity of a T Cell Receptor α Chain Generated by Expression PCR

scientific article published on 01 May 1995

Antisense oligodeoxynucleotides as probes of T-lymphocyte gene function

scientific article published on October 28, 1992

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.

scientific article

Apoptosis and cancer: the failure of controls on cell death and cell survival.

scientific article

Apoptosis and oncogenesis: give and take in the BCL-2 family

scientific article published on 13 January 2011

Apoptosis therapy: driving cancers down the road to ruin

scientific article published in February 2013

Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.

scientific article published on 09 January 2016

Apoptosis: Stabbed in the BAX.

scientific article published in October 2008

Apoptosis: checkpoint at the mitochondrial frontier.

scientific article

Apoptosis: letting slip the dogs of war.

scientific article

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

scientific article

Apoptotic cells induce tolerance by generating helpless CD8+ T cells that produce TRAIL.

scientific article published in March 2007

Apoptotic gene therapy in the interdigital web.

scientific article

Apoptotic pathways: ten minutes to dead

scientific article

Armed response: how dying cells influence T-cell functions

scientific article

At the gates of death

scientific article published in May 2006

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

scientific article

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

scientific article

Autophagy and phagocytosis converge for better vision

scientific article

Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels

scientific article

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

scientific article published on 25 January 2016

Autophagy is a cell survival program for female germ cells in the murine ovary

scientific article published on 4 April 2011

Autophagy is essential for effector CD8(+) T cell survival and memory formation

scientific article

Autopsy of a cell

scientific article published on 14 January 2014

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

scientific article

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

scientific article (publication date: 18 February 2005)

BID-induced structural changes in BAK promote apoptosis

scientific article

BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation

scientific journal article

Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.

scientific article

Bcr - Abl-mediated resistance to apoptosis is independent of PI 3-kinase activity.

scientific article published in October 1997

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

scientific article (publication date: November 2002)

Biological events and molecular signaling following MLKL activation during necroptosis

scientific article published on 30 August 2017

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

scientific article

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

scientific article

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

scientific article published in March 2005

CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes

scientific article published on 26 April 2016

Calcium and energy: making the cake and eating it too?

scientific article published on July 2010

Calpain activation is upstream of caspases in radiation-induced apoptosis.

scientific article published on December 1998

Cancer and Apoptosis: Who Is Built to Last?

scientific article published in January 2017

Cancer: A wolf in wolf's clothing

scientific article published in May 2010

Carmine Melino.

scientific article published in September 2017

Caspase 8 inhibits programmed necrosis by processing CYLD ⬇️

scientific article published on October 30, 2011

Caspase-1 inflammasomes: choosing between death and taxis.

scientific article published in September 2007

Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity

scientific article published in March 2008

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

scientific journal article

Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.

scientific article published on 22 February 2006

Caspase-2-mediated cell death is required for deleting aneuploid cells

scientific article

Caspase-2: the orphan caspase.

scientific article

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

scientific article published on October 1999

Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival.

scientific article published on 23 January 2009

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

scientific article

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans

scientific article published on 25 July 2014

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

scientific article published on 24 June 2015

Caspase-8: regulating life and death

scientific article

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

scientific article

Cell Death Signaling

scientific article

Cell biology. Metabolic control of cell death

scientific article

Cell competition: pirates on the tangled bank

scientific article

Cell death and immune privilege

scientific article

Cell death and the immune system: getting to how and why.

scientific article

Cell death and tissue remodeling in planarian regeneration

scientific article

Cell survival in tough times: The mitochondrial recovery plan

scientific article published on 13 November 2010

Cell-Extrinsic TNF Collaborates with TRIF Signaling To Promote Yersinia-Induced Apoptosis

scientific article published on 12 October 2016

Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis

scientific article published on 29 May 2015

Characterization of cytoplasmic caspase-2 activation by induced proximity.

scientific article

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

scientific article

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.

scientific article

Class I MHC mediates programmed cell death in a Fas-independent manner.

scientific article published on February 1997

Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.

scientific article published on August 1999

Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains

scientific article

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

scientific article published in October 2005

Contrasuppression in the mouse

scientific article published on 01 March 1986

Contrasuppression. A novel immunoregulatory activity

scientific article published in June 1981

Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

scientific article

Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

scientific article published on 28 September 2016

Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis

scientific article published on 23 March 2016

Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway

scientific article published on 31 January 2014

Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

scientific article published on 9 November 2012

Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways

scientific article

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

scientific article

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

scientific article

Cytochrome c: functions beyond respiration

scientific article published on July 2008

Cytoplasmic functions of the tumour suppressor p53.

scientific article published on April 2009

DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1 ⬇️

scientific article published on March 1, 1998

DUB-le Trouble for Cell Survival

scientific article published in February 2010

Death and NF-kappaB in T cell activation: life at the edge

scientific article

Death fold domain interaction in apoptosis

scientific article (publication date: 2003)

Death receptors and mitochondria: life depends on the liver

scientific article published in July 2011

Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils

scientific article published in January 2002

Detection of caspase activity using antibody-based techniques

scientific article published in July 2014

Developmental checkpoints guarded by regulated necrosis

scientific article published on 7 April 2016

Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-α-induced shock.

scientific article

Dicing with death: dissecting the components of the apoptosis machinery.

scientific article

Die another way--non-apoptotic mechanisms of cell death

scientific article (publication date: 15 May 2014)

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration

scientific article

Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity

scientific article published on 12 June 2017

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

scientific article

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control

scientific article

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

scientific article

Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells

scientific article

Dissecting p53-dependent apoptosis.

scientific article

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

scientific article published in February 1999

Distinct roles of cytolytic effector molecules for antigen-restricted killing by CTL in vivo

scientific article published on 23 March 2010

Do inducers of apoptosis trigger caspase-independent cell death?

scientific article published in March 2005

Downregulation of Bcr-Abl in K562 cells restores susceptibility to apoptosis: characterization of the apoptotic death.

scientific article published on February 1997

Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion

scientific article published in July 2006

Dynamic programming of CD8+ T lymphocyte responses

article

Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death

scientific article

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

scientific article published on April 2017

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl ⬇️

scientific article published on November 1, 1995

Eating for good health: linking autophagy and phagocytosis in host defense

scientific article published on 03 June 2008

Eating the Beast: Dietary Protein and Anticancer Immunity

scientific article published on 01 April 2018

Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses

scientific article

Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy

scientific article

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

scientific article (publication date: 20 April 2006)

Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria

scientific article published on 12 January 2018

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.

scientific article published on 25 September 2017

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

scientific article published on 22 January 2014

FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

scientific article published on February 2011

Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo

scientific article published on 01 September 1995

Fas Bim boom!

scientific article published in February 2008

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

scientific article published on 01 November 1995

Fas ligand, death gene.

scientific article

Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease ⬇️

scientific article published on February 1, 1998

Fas-Ligand and Immune Privilege: The Eyes Have It

scientific article published on 01 July 2001

Functional Myc-Max heterodimer is required for activation-induced apoptosis in T cell hybridomas.

scientific article published on December 1994

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

scientific article published in June 2007

Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release

scientific article

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

scientific article

Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

scientific article published on 03 May 2013

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

scientific article

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

scientific article

Gone but not forgotten

scientific article published on 01 May 2000

Granzyme A: the road less traveled

scientific article (publication date: February 2003)

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

scientific article published in December 1998

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

scientific article

HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation

scientific article

HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells

scientific article (publication date: 4 October 2002)

HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B.

scientific article published on October 1997

Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium.

scientific article

Harm's way: polyglutamine repeats and the activation of an apoptotic pathway.

scientific article published on March 1999

Highly conserved caspase and Bcl-2 homologues from the sea anemone Aiptasia pallida: lower metazoans as models for the study of apoptosis evolution

scientific article published on 10 June 2006

Histoincompatibility in vertebrates: the relict hypothesis.

scientific article

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis

scientific article

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

scientific article published on 07 March 2008

Hyperimmunity and the decision to be intolerant ⬇️

scientific article published on January 1, 1982

ICE Heats Up

scientific article published on 01 June 2001

IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells

scientific article

Immunogenic and tolerogenic cell death

scientific article

Immunology: A heavyweight knocked out.

scientific article published on 2 November 2011

Immunoregulatory T-cell pathways.

scientific article

Immunoregulatory activity of a T-cell receptor alpha chain demonstrated by in vitro transcription and translation.

scientific article

Immunoregulatory activity of the T-cell receptor alpha chain demonstrated by retroviral gene transfer ⬇️

scientific article published on October 1, 1991

Immunoregulatory circuits which modulate responsiveness to suppressor cell signals: characterization of an effector cell in the contrasuppressor circuit

scientific article published on 01 December 1981

Immunoregulatory circuits which modulate responsiveness to suppressor cell signals: contrasuppressor cells can convert anin vivo tolerogenic signal into an immunogenic one

scientific article published on 01 December 1981

In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis

scientific article published on 18 December 2005

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation

scientific article

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation

scientific article published in 2014

Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein

scientific article

Inhibition of TNF-induced apoptosis by NF-κB ⬇️

scientific article published on March 1, 1998

Innate immune recognition of mtDNA--an undercover signal?

scientific article published on June 2015

Interleukin-2 rescues helpless effector CD8+ T cells by diminishing the susceptibility to TRAIL mediated death

scientific article

Introduction: apoptosis in the development and function of the immune system ⬇️

scientific article published on June 1, 2003

Is SIRT2 required for necroptosis?

scientific article published on February 2014

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

scientific article published on 21 October 2011

Just So Stories about the Evolution of Apoptosis

scientific article

Knockdown of actin and caspase gene expression by RNA interference in the symbiotic anemone Aiptasia pallida

scientific article published in June 2007

LC3-Associated Phagocytosis and Inflammation.

scientific article published on 25 August 2017

LC3-associated phagocytosis at a glance

scientific article published on 20 February 2019

Life support: the alpha4 phosphatase subunit in cell survival and apoptosis

scientific article published in June 2005

Life, death, BH3 profiles, and the salmon mousse

scientific article published on August 2007

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy

scientific article published on 26 December 2017

Live to dead cell imaging

scientific article

Living with death: the evolution of the mitochondrial pathway of apoptosis in animals.

scientific article published on 02 May 2008

Lymphocyte apoptosis: refining the paths to perdition

scientific article

Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc.

scientific article published on January 1994

MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis

scientific article

MOMP, cell suicide as a BCL-2 family business

scientific article published on 20 October 2017

Manipulation of apoptosis in the host-parasite interaction

scientific article published on June 2004

Many players in BCL-2 family affairs

scientific article published on 03 February 2014

Measuring apoptosis at the single cell level

scientific article published on March 2008

Measuring apoptosis: caspase inhibitors and activity assays

scientific article published in August 2014

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

scholarly article

Metabolic activation of CaMKII by coenzyme A.

scientific article published on 03 October 2013

Metabolic checkpoints in activated T cells

scientific article published on 18 September 2012

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

scientific article

Metabolic reprogramming and metabolic dependency in T cells ⬇️

scientific article published on September 1, 2012

Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells

scientific article published on 10 March 2014

Metabolism and immunity: The old and the new ⬇️

scientific article published on December 1, 2012

Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity

scientific article published in September 2002

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

scientific article

Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins.

scientific article published on 17 March 2003

Mito-priming as a method to engineer Bcl-2 addiction.

scientific article

Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

scientific article

Mitochondria and apoptosis

scientific article (publication date: 28 August 1998)

Mitochondria and apoptosis: HQ or high-security prison?

scientific article

Mitochondria and apoptosis: a quick take on a long view

scientific article

Mitochondria and cell death: outer membrane permeabilization and beyond

scientific article (publication date: September 2010)

Mitochondria and cell signalling

scientific article published in February 2012

Mitochondria and the autophagy-inflammation-cell death axis in organismal aging ⬇️

scientific article published on August 26, 2011

Mitochondria are required for pro-ageing features of the senescent phenotype.

scientific article

Mitochondria in cell death

scientific article published in January 2010

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

scientific article published in January 1998

Mitochondrial dysfunction in ataxia-telangiectasia

scientific article

Mitochondrial functions during cell death, a complex (I–V) dilemma ⬇️

scientific article published on May 1, 2003

Mitochondrial pathway of apoptosis is ancestral in metazoans

scientific article published on 13 March 2012

Mitochondrial regulation of cell death.

scientific article published on September 2013

Molecular Cell Biology of Apoptosis and Necroptosis in Cancer

scientific article published in January 2016

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

scientific article (publication date: 2012)

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Mostly dead

scientific article published on 01 July 2001

Mouse genome engineering via CRISPR-Cas9 for study of immune function

scientific article

Murder by proxy

scientific article published on 01 December 2000

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

scientific article published on 11 December 2014

NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2

scientific article

Nab2 regulates secondary CD8+ T-cell responses through control of TRAIL expression

scientific article published on 29 November 2011

Necroptosis

scientific article

Necroptosis in development, inflammation and disease.

scientific article published on 21 December 2016

Non-apoptotic role of BID in inflammation and innate immunity

scientific article published on 8 May 2011

Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes

scientific article published on 06 December 2012

Noncanonical autophagy promotes the visual cycle

scientific article published on July 2013

Noncanonical function of an autophagy protein prevents spontaneous Alzheimer's disease

scientific article published on 14 August 2020

Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion

scientific article

Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells

scientific article published in June 2014

Novel roles for GAPDH in cell death and carcinogenesis.

scientific article published on 25 September 2009

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

scientific article

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

scientific article

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.

scientific article published on 2 November 2007

Overview: apoptotic signaling pathways in the immune system

scientific article

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

scientific article

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

scientific article

PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis

scientific article published on 02 September 2009

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

scientific article

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

scientific article

Pharmacological manipulation of cell death: clinical applications in sight?

scientific article

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

scientific article

Phenytoin inhibits necroptosis

scientific article published on 2 March 2018

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53

scientific article

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

scientific article published on 29 July 2015

Polarization and asymmetry in T cell metabolism

scientific article

Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.

scientific article published on 9 February 2012

Preparation of cytosolic extracts and activation of caspases by cytochrome c.

scientific article published in July 2014

Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells

scientific article published in December 2003

Pro-caspase-3 is a major physiologic target of caspase-8.

scientific article published in October 1998

Programmed necrosis in inflammation: Toward identification of the effector molecules

scientific article

Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1α-dependent

scientific article published on 25 January 2016

Promotion and Inhibition of Activation‐Induced Apoptosis in T‐Cell Hybridomas by Oncogenes and Related Signals ⬇️

scientific article published on December 1, 1994

Protease activation during apoptosis: death by a thousand cuts?

scientific article published on August 1995

Protective roles for caspase-8 and cFLIP in adult homeostasis.

scientific article published on 03 October 2013

Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.

scientific article published in November 1994

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

scientific article published on March 1995

Pseudokiller, qu'est-ce que c'est?

scientific article published on September 2013

Publications in cell death: the golden age.

scientific article

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

retracted scholarly article

RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts

scientific article

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

scientific article

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

scientific article

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

scientific article

RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.

scientific article

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.

scientific article published on 15 June 2016

RIPped for neuroinflammation

scientific article published on 19 May 2017

RIPped for neuroinflammation

scientific article published on August 2017

Real time with caspase-2.

scientific article published on 30 January 2010

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

scientific article published on 24 March 2013

Regional analysis of p53 mutations in rheumatoid arthritis synovium

scientific article

Regulation of FasL by NF-κB and AP-1 in Fas-dependent Thymineless Death of Human Colon Carcinoma Cells

scientific article published on 01 April 2000

Regulation of activation-induced Fas (CD95/Apo-1) ligand expression in T cells by the cyclin B1/Cdk1 complex

scientific article published on 23 June 2004

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL.

scientific article published on 5 March 2018

Regulation of arthritis by p53: critical role of adaptive immunity

scientific article published in June 2005

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

scientific article published in January 1999

Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis

scientific article published on January 2002

RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

scientific article published in Journal of Biological Chemistry

Remodeling for Demolition

scientific article published on 01 January 2002

Resistance to caspase-independent cell death requires persistence of intact mitochondria

scientific article published on May 2010

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

scientific article

Ripped to death

scientific article

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

scientific article published on July 10, 1992

Role of Bcl-2 family members in immunity and disease

scientific article published on March 2004

Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells.

scientific article

Role of acidic sphingomyelinase in Fas/CD95-mediated cell death.

scientific article published on March 2000

Role of contrasuppression in the adoptive transfer of immunity ⬇️

scientific article published on September 1, 1983

Role of proteolysis in caspase-8 activation and stabilization

scientific article published on 20 March 2007

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

scientific article

Saying the 'S' word in public.

scientific article

Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis

scientific article published on 3 February 2016

SnapShot: Mitochondrial quality control

scientific article published on November 2011

Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

scientific article published on September 1997

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

scientific article

Stress in Biomedical Research: Six Impossible Things ⬇️

scientific article published on October 22, 2010

Suppression and contrasuppression in the regulation of gut-associated immune responses ⬇️

scientific article published on June 30, 1983

Surviving the cytochrome seas.

scientific article published in October 1998

Sweet nothings: sensing of sugar metabolites controls T cell function

scientific article published on July 2013

Synchronized renal tubular cell death involves ferroptosis. ⬇️

scientific article

Synergistic action of protein kinase C θ and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells

scientific article published on 01 November 1999

Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy.

scientific article published on January 2013

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

scientific article

T cell development: Some cells get all the breaks

article

T cell metabolism and the immune response

scientific article published on December 2012

T cells are just dying to accept grafts

scientific article published on 01 November 1999

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

scientific journal article

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox

scientific article published on 6 July 2017

Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention

scientific article published on May 2017

Ten years of publication in cell death

scientific article published on 01 January 2004

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

scientific article

The BCL-2 family reunion

scientific article published on February 2010

The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity.

scientific article

The DNA-binding domain mediates both nuclear and cytosolic functions of p53

scientific article

The End and After: How Dying Cells Impact the Living Organism ⬇️

scientific article published on October 28, 2011

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

scientific article

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis

scientific article published on May 2016

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.

scientific article published in June 2016

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

scientific article

The Relationship between Metabolism and the Autophagy Machinery during the Innate Immune Response ⬇️

scientific article published on June 4, 2013

The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway

scientific article

The cell's dilemma, or the story of cell death: an entertainment in three acts

scientific article

The clearance of dead cells by efferocytosis

scientific article published on 06 April 2020

The immune diet: meeting the metabolic demands of lymphocyte activation

scientific article published on 2 May 2012

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

scientific journal article

The killer and the executioner: how apoptosis controls malignancy.

scientific article published on October 1995

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

scientific article published on October 2002

The machinery of programmed cell death.

scientific article

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

scientific article

The neoepitope landscape in pediatric cancers.

scientific article published on 31 August 2017

The pantheon of the fallen: why are there so many forms of cell death?

scientific article published on 17 September 2012

The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage

scientific article published on 28 July 2017

The regulation of apoptotic cell death.

scientific article

The role of ARK in stress-induced apoptosis in Drosophila cells

scientific article

The role of Fas ligand in immune privilege ⬇️

scientific article published on December 1, 2001

The role of p53 and Fas in a model of acute murine graft-versus-host disease

scientific article

The suicide in the thymus, a twisted trail

scientific article published on 01 March 2003

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

scientific article

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function

scientific article

The two faces of receptor interacting protein kinase-1

scientific article

The ubiquitin-protein ligase Itch regulates p73 stability

scientific article

To be or not to be? How selective autophagy and cell death govern cell fate

scientific article

Toll-like receptor signaling in the lysosomal pathways

scientific article published on January 2009

Transcription, apoptosis and p53: catch-22.

scientific article

Trauma and the immune response

scientific article published on 01 September 1988

Tumor necrosis factor alpha up-regulates non-lymphoid Fas-ligand following superantigen-induced peripheral lymphocyte activation

scientific article

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

scientific article published on July 2013

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

scientific article

Uptake of Apoptotic Antigen-Coupled Cells by Lymphoid Dendritic Cells and Cross-Priming of CD8+ T Cells Produce Active Immune Unresponsiveness

scientific article published on 01 June 2002

Verification of a putative caspase substrate

scientific article published in August 2014

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

scientific article

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

scientific article published on 21 November 2013

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

scientific article

p34cdc2 and apoptosis

scientific article

p53 and metabolism: Inside the TIGAR.

scientific article

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

scientific article published on March 2000

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

scientific article published on 01 April 2003

p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis

scientific article

p53's believe it or not: lessons on transcription-independent death

scientific article published on September 1, 2003

p53-dependent radiation-induced crypt intestinal epithelial cells apoptosis is mediated in part through TNF-TNFR1 system

scientific article published on 01 February 2001

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