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List of works by James Cuthbert Smith

A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis

scientific article published in February 2018

A Xenopus tropicalis oligonucleotide microarray works across species using RNA from Xenopus laevis

scientific article published on 26 October 2004

A divergent Tbx6-related gene and Tbx6 are both required for neural crest and intermediate mesoderm development in Xenopus

scientific article

A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation

scholarly article

A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus

scientific article

A mechanism regulating the onset of Sox2 expression in the embryonic neural plate

scientific article

A mesoderm-inducing factor is produced by Xenopus cell line.

scientific article published in January 1987

A screen for targets of the Xenopus T-box gene Xbra

scientific article

A short loop on the ALK-2 and ALK-4 activin receptors regulates signaling specificity but cannot account for all their effects on early Xenopus development

scientific article published in March 1999

Active cell migration drives the unilateral movements of the anterior visceral endoderm

scientific article

Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B.

scientific article published on 15 September 2004

An Overview of Xenopus Development

article

An anterior signalling centre in Xenopus revealed by the homeobox gene XHex

scientific article published in September 1999

Analysis of gastrulation: different types of gastrulation movement are induced by different mesoderm-inducing factors in Xenopus laevis

scientific article published in September 1993

Are beta 1 integrins involved in Xenopus gastrulation?

scientific article published in August 1992

Attenuation of positional signalling in the chick limb by high doses of γ-radiation

scientific article published in Nature

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages

scientific article published on August 2011

Biochemical specificity of Xenopus notochord

scientific article published on 01 January 1985

Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells

scientific article published on 26 May 2015

Brachyury and the T-box genes ⬇️

scientific article published on August 1, 1997

CVAK104 is a novel regulator of clathrin-mediated SNARE sorting

scientific article

Ch-ch-ch-ch-changes..

Changes in states of commitment of single animal pole blastomeres of Xenopus laevis

scientific article published in February 1987

Chapter 32 Xenopus Cell Lines

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection

scientific article

Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition.

scientific article published on July 2017

Common and distinct transcriptional signatures of mammalian embryonic lethality

scientific article published on 26 June 2019

Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes

scientific article

Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex

scientific article

Control of somitic expression of tenascin in Xenopus embryos by myogenic factors and Brachyury

scientific article published on 01 August 1994

Control of vertebrate gastrulation: inducing signals and responding genes

scientific article

Controlling morpholino experiments: don't stop making antisense.

scientific article

Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes.

scientific article published on 6 April 2017

Crossing the threshold

scientific article published in September 1992

DNA-binding specificity and embryological function of Xom (Xvent-2).

scientific article published in December 1999

Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

scientific article published on 18 March 2013

Defining a large set of full-length clones from a Xenopus tropicalis EST project

scientific article published on July 2004

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides

scientific article

Development and `open access'

article

Development in 2007: new developments and sad goodbyes

article

Development: moving on in 2006.

scientific article published in January 2006

Developmental biology. Angles on activin's absence

scientific article published in March 1995

Differential effects on Xenopus development of interference with type IIA and type IIB activin receptors.

scientific article published in January 1997

Dissecting and Culturing Animal Cap Explants

article

Distinct Enhancer Elements Control Hex Expression during Gastrulation and Early Organogenesis

article published in 2001

Dorso-ventral patterning in the neural tube

scientific article published in September 1993

Downstream of FGF during mesoderm formation in Xenopus: the roles of Elk-1 and Egr-1.

scientific article published on 30 September 2009

Dynamic regulation of Brachyury expression in the amphibian embryo by XSIP1.

scientific article published in February 2002

Effects of biochemical inhibitors on positional signalling in the chick limb bud

scientific article published on April 1, 1981

Efficient Preparation of High-Complexity ChIP-Seq Profiles from Early Xenopus Embryos.

scientific article

Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

scientific article

Establishment of a BMP-4 morphogen gradient by long-range inhibition

scientific article published in February 1998

Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data

scientific article

Evidence for a positional memory in the development of the chick wing bud

scientific article published on August 1, 1979

Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria

scientific article (publication date: 15 August 2003)

Expression of tenascin mRNA in mesoderm during Xenopus laevis embryogenesis: the potential role of mesoderm patterning in tenascin regionalization

scientific article

FAM83F regulates canonical Wnt signalling through an interaction with CK1α

scientific article published on 24 December 2020

Fates and states of determination of single vegetal pole blastomeres of X. laevis

scientific article published on 01 May 1984

Forming and interpreting gradients in the early Xenopus embryo

scientific article published on July 2009

Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1.

scientific article published in April 2005

Gastrulation and larval pattern in Xenopus after blastocoelic injection of a Xenopus-derived inducing factor: Experiments testing models for the normal organization of mesoderm

scientific article published on 01 February 1989

Genome-wide snapshot of chromatin regulators and states in Xenopus embryos by ChIP-Seq

scientific article

Germ layer induction in ESC--following the vertebrate roadmap

scientific article published in June 2007

Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development

scientific article published on 13 October 2012

Gradual refinement of activin-induced thresholds requires protein synthesis

scientific article published in January 2000

Growth and the origin of additional structures in reduplicated chick wings

scientific article published on 01 January 1983

Growth factors adherent to cell substrate are mitogenically active in situ

scientific article published in Nature

Growth factors as morphogens: do gradients and thresholds establish body plan?

scientific article published on August 1991

Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?

scientific article

Hedgehog, the floor plate, and the zone of polarizing activity

scientific article published on January 1994

Hello goodbye

2008 scholarly article by James Cuthbert Smith

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

scientific article

Identification and characterisation of the posteriorly-expressed Xenopus neurotrophin receptor homolog genes fullback and fullback-like

article

Identification of direct T-box target genes in the developing zebrafish mesoderm

scientific article published on 21 January 2009

Identification of the zebrafish maternal and paternal transcriptomes

scientific article published on 29 May 2013

Identification of two amino acids in activin A that are important for biological activity and binding to the activin type II receptors

scientific article

In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency

scientific article published on 19 September 2013

Induction and early amphibian development

scientific article published on December 1989

Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm

scientific article published on 27 April 2005

Inductive interactions in early amphibian development

scientific article published on December 1990

Inductive interactions in early embryonic development

scientific article published on August 1991

Inductive signals. Revolving vertebrates

scientific article published on June 1995

Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus.

scientific article published on 17 February 2018

Interference with brachyury function inhibits convergent extension, causes apoptosis, and reveals separate requirements in the FGF and activin signalling pathways

scientific article published in September 1999

Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists

scientific article

Introduction. Calcium signals and developmental patterning

scientific article published on April 2008

Investigating physical chromatin associations across the Xenopus genome by chromatin immunoprecipitation

scientific article

KazrinA is required for axial elongation and epidermal integrity in Xenopus tropicalis

scientific article published in June 2008

Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo.

scientific article published on 16 November 2017

Loss of REEP4 causes paralysis of the Xenopus embryo

scientific article published in January 2009

Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53

scientific article

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

scientific article published on 17 August 2018

Many ways to make a gradient

scientific article published in July 2004

Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

scientific article published on 19 September 2019

Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals

Measurement of developmental time by cells of early embryos

scientific article published on March 1990

Mesoderm formation in response to Brachyury requires FGF signalling

scientific article published in January 1995

Mesoderm induction assays

scientific article published on January 2008

Mesoderm induction in Xenopus caused by activation of MAP kinase

scientific article

Mesoderm-inducing factors and mesodermal patterning

scientific article published on December 1995

Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance

scientific article

Microarray-based identification of VegT targets in Xenopus

scientific article

Mix.1/2-dependent control of FGF availability during gastrulation is essential for pronephros development in Xenopus

scientific article published on 9 July 2008

Molecular components of the endoderm specification pathway in Xenopus tropicalis

scientific article

Neurotrophin receptor homolog (NRH1) proteins regulate mesoderm formation and apoptosis during early Xenopus development

scientific article published on 28 September 2006

New insights into the maternal to zygotic transition

scientific article

New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites

scientific article

Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation.

scientific article published in November 1995

Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus

scientific article published on 24 October 2007

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

scientific article

PAWS1 controls Wnt signalling through association with casein kinase 1α.

scientific article

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.

scientific article published on 24 November 2017

Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling

scientific article published on 09 September 2019

Pattern formation along the anteroposterior axis of the chick wing: the increase in width following a polarizing region graft and the effect of X-irradiation

scientific article published on 01 June 1981

Placentation defects are highly prevalent in embryonic lethal mouse mutants

scientific article published on 14 March 2018

Pointing a digit at digitised JEEM.

scientific article published in August 2008

Positional signalling: where are we now?

scientific article published on June 1989

Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo

scientific article published on 6 June 2008

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling

scientific article

Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus

scientific article

Refinement of gene expression patterns in the early Xenopus embryo

scientific article

Regulation of apoptosis in theXenopus embryo by Bix3.

scientific article published in October 2003

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

scientific article published in November 1992

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes

scientific article

Smicl is required for phosphorylation of RNA polymerase II and affects 3'-end processing of RNA at the midblastula transition in Xenopus

scientific article published on October 2009

Spatial and temporal patterns of cell division during early Xenopus embryogenesis

scientific article published in January 2001

Stem cells in Development: new editor, renewed commitment

article

T-box genes: what they do and how they do it.

scientific article

T-targets: clues to understanding the functions of T-box proteins

scientific article

Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates

scientific journal article

Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis

scientific article published on 5 January 2005

Techniques and probes for the study of Xenopus tropicalis development

scientific article published in December 2002

Tes regulates neural crest migration and axial elongation in Xenopus

scientific article published on 22 March 2006

The ARID domain protein dril1 is necessary for TGF(beta) signaling in Xenopus embryos

scientific article

The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.

scientific article

The Wnt/beta-catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signalling

scientific article

The Xenopus animal pole blastomere

scientific article published on November 1987

The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression

scientific article

The accidental biologist: an interview with Jim Smith by Weston Kathy

scientific article published in January 2010

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

scientific article published on 24 August 2016

The midblastula transition defines the onset of Y RNA-dependent DNA replication in Xenopus laevis

scientific article

The molecular basis of positional information

scientific article published on September 1, 1991

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo

scientific article

The origin of the mesoderm in an anuran, Xenopus laevis, and a urodele, Ambystoma mexicanum

scientific article published on 01 July 1983

The time required for positional signalling in the chick wing bud

scientific article published on 01 December 1980

TheXenopus Brachyurypromoter is activated by FGF and low concentrations ofactivinandsuppressed by high concentrationsof activin and by paired-type homeodomain proteins ⬇️

scientific article published on December 1, 1997

Titration of four replication factors is essential for the Xenopus laevis midblastula transition

scientific article

Transcriptional regulation of mesendoderm formation in Xenopus

scientific article

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling

scientific article

Understanding how morphogens work

scientific article published on April 2008

Vegetal pole cells and commitment to form endoderm in Xenopus laevis

scientific article

Visualisation and quantification of morphogen gradient formation in the zebrafish

scientific article (publication date: May 2009)

Visualizing long-range movement of the morphogen Xnr2 in the Xenopus embryo

scientific article published in November 2004

Visualizing protein interactions by bimolecular fluorescence complementation in Xenopus

scientific article published on 27 June 2008

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13

scientific article published on 17 August 2020

Whither development and developmental biology?

scientific article published in January 2008

Wholemount in situ hybridization to Xenopus embryos

scientific article published on January 2008

Wise, a context-dependent activator and inhibitor of Wnt signalling

scientific article

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development

scientific article published on 5 January 2005

XSIP1, a Xenopus zinc finger/homeodomain encoding gene highly expressed during early neural development

scientific article published in June 2000

Xenopus Brachyury

article

Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling

scientific article

Xenopus genetics and genomics

scientific article

Xnrs and activin regulate distinct genes during Xenopus development: activin regulates cell division

scientific article

Xwnt11 and the regulation of gastrulation in Xenopus.

scientific article

Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes

scientific article

Zebrafish promoter microarrays identify actively transcribed embryonic genes.

scientific article published on 4 August 2006

no tail integrates two modes of mesoderm induction

scientific article

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