List of works - Susan Gottesman

A PhoQ/P-regulated small RNA regulates sensitivity of Escherichia coli to antimicrobial peptides

scientific article

A complex network of small non-coding RNAs regulate motility in Escherichia coli

scientific article

A genetic approach for finding small RNAs regulators of genes of interest identifies RybC as regulating the DpiA/DpiB two-component system

scientific article (publication date: May 2009)

A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli

scientific article

Acidic Residues in the Hfq Chaperone Increase the Selectivity of sRNA Binding and Annealing

scientific article

Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition

scientific article

Alternative pathways for Escherichia coli biofilm formation revealed by sRNA overproduction.

scientific article published on 4 May 2017

An antibody-based microarray assay for small RNA detection

scientific article

Analysis of the Escherichia coli Alp phenotype: heat shock induction in ssrA mutants

scientific article

Anti-adaptors provide multiple modes for regulation of the RssB adaptor protein

scientific article

Bacterial small RNA regulators

scientific article

Bacterial small RNA-based negative regulation: Hfq and its accomplices

scientific article

C-terminal domain of the RNA chaperone Hfq drives sRNA competition and release of target RNA.

scientific article published on 28 September 2016

Cell biology: Phosphate on, rubbish out.

scientific article published on 2 November 2016

Competition among Hfq-binding small RNAs in Escherichia coli

scientific article

Complex transcriptional and post-transcriptional regulation of an enzyme for lipopolysaccharide modification

scientific article published on 31 May 2013

Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli

scientific article published on 15 September 2003

Dicing defence in bacteria

scientific article published in Nature

Effect of RyhB small RNA on global iron use in Escherichia coli

scientific article

Genetic dissection of signaling through the Rcs phosphorelay.

scientific article published in January 2007

Global analysis of small RNA and mRNA targets of Hfq

scientific article (publication date: November 2003)

Hfq links translation repression to stress-induced mutagenesis in E. coli

scientific article published on 9 August 2017

Hfqs in Bacillus anthracis: Role of protein sequence variation in the structure and function of proteins in the Hfq family ⬇️

scientific article

Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis

scientific article

IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein

scientific article published on 27 July 2020

In vivo characterization of an Hfq protein encoded by the Bacillus anthracis virulence plasmid pXO1 ⬇️

scientific article

Integrating anaerobic/aerobic sensing and the general stress response through the ArcZ small RNA

scientific article

Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system

scientific article

Mechanism of positive regulation by DsrA and RprA small noncoding RNAs: pairing increases translation and protects rpoS mRNA from degradation

scientific article

Meeting report: Regulating with RNA in Bacteria 2013.

scientific article published on 12 June 2014

MicA sRNA links the PhoP regulon to cell envelope stress

scientific article

Micros for microbes: non-coding regulatory RNAs in bacteria

scientific article

Modes of regulation of RpoS by H-NS

scientific article

Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli

scientific article

Modulating the outer membrane with small RNAs

scientific article published on September 2006

Multiple in vivo roles for the C-terminal domain of the RNA chaperone Hfq

scientific article published on 01 February 2022

Multiple pathways for regulation of sigmaS (RpoS) stability in Escherichia coli via the action of multiple anti-adaptors

scientific article published in April 2008

Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets

scientific article

New aspects of RNA-based regulation by Hfq and its partner sRNAs

scientific article published on 7 November 2017

Not just Salk

scientific article published in September 2017

Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system

scientific article published in March 2004

Positive regulation by small RNAs and the role of Hfq

scientific article

Proteolysis in Bacterial Regulatory Circuits ⬇️

scientific article published on January 1, 2003

RNA reflections: converging on Hfq

scientific article

RNase E finds some sRNAs stimulating

scientific article

Regulating the regulator: an RNA decoy acts as an OFF switch for the regulation of an sRNA.

scientific article published on September 2009

Regulation and mode of action of the second small RNA activator of RpoS translation, RprA

scientific article (publication date: November 2002)

Regulation of acetate metabolism and coordination with the TCA cycle via a processed small RNA

scientific article published on 27 December 2018

Regulatory roles for small RNAs in bacteria ⬇️

scientific article published on April 1, 2003

Remodelling of the Escherichia coli outer membrane by two small regulatory RNAs

scientific article

Role of RcsF in signaling to the Rcs phosphorelay pathway in Escherichia coli

scientific article

Role of polynucleotide phosphorylase in sRNA function in Escherichia coli

scientific article

Roles of adaptor proteins in regulation of bacterial proteolysis

scientific article published on 31 January 2013

SigmaE regulates and is regulated by a small RNA in Escherichia coli

scientific article

Small RNA Regulation of TolC, the Outer Membrane Component of Bacterial Multidrug Transporters

scientific article published on 25 January 2016

Small RNAs shed some light

scientific article published in July 2004

Spot 42 sRNA regulates arabinose-inducible araBAD promoter activity by repressing synthesis of the high-affinity low-capacity arabinose transporter

scientific article published on 14 November 2016

Stealth regulation: biological circuits with small RNA switches

scientific article

Stress Reduction, Bacterial Style

scientific article published on 31 July 2017

Stress sigma factor RpoS degradation and translation are sensitive to the state of central metabolism

scientific article published on 6 April 2015

Structural basis for inhibition of a response regulator of σS stability by a ClpXP antiadaptor

scientific article published on 11 April 2019

The 5' end of two redundant sRNAs is involved in the regulation of multiple targets, including their own regulator

scientific article

The Crp-activated small noncoding regulatory RNA CyaR (RyeE) links nutritional status to group behavior

scientific article published on 31 October 2008

The MiaA tRNA modification enzyme is necessary for robust RpoS expression in Escherichia coli

scientific article published on 02 December 2013

The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica

scholarly article

The Rcs phosphorelay: a complex signal transduction system

scientific article

The RpoS-mediated general stress response in Escherichia coli

scientific article

The novel transcription factor SgrR coordinates the response to glucose-phosphate stress

scientific article

Translational regulation of the Escherichia coli stress factor RpoS: a role for SsrA and Lon

scientific article published on 20 April 2007

Unexpected properties of sRNA promoters allow feedback control via regulation of a two-component system ⬇️

scientific article published on 20 July 2016

ppGpp regulation of RpoS degradation via anti-adaptor protein IraP.

scholarly article

sRNA roles in regulating transcriptional regulators: Lrp and SoxS regulation by sRNAs

scientific article published on 02 May 2016

sRNA-Mediated Control of Transcription Termination in E. coli

scientific article

List of works by Susan Gottesman

A PhoQ/P-regulated small RNA regulates sensitivity of Escherichia coli to antimicrobial peptides

A complex network of small non-coding RNAs regulate motility in Escherichia coli

A genetic approach for finding small RNAs regulators of genes of interest identifies RybC as regulating the DpiA/DpiB two-component system

A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli

Acidic Residues in the Hfq Chaperone Increase the Selectivity of sRNA Binding and Annealing

Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition

Alternative pathways for Escherichia coli biofilm formation revealed by sRNA overproduction.

An antibody-based microarray assay for small RNA detection

Analysis of the Escherichia coli Alp phenotype: heat shock induction in ssrA mutants

Anti-adaptors provide multiple modes for regulation of the RssB adaptor protein

Bacterial small RNA regulators

Bacterial small RNA-based negative regulation: Hfq and its accomplices

C-terminal domain of the RNA chaperone Hfq drives sRNA competition and release of target RNA.

Cell biology: Phosphate on, rubbish out.

Competition among Hfq-binding small RNAs in Escherichia coli

Complex transcriptional and post-transcriptional regulation of an enzyme for lipopolysaccharide modification

Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli

Dicing defence in bacteria

Effect of RyhB small RNA on global iron use in Escherichia coli

Genetic dissection of signaling through the Rcs phosphorelay.

Global analysis of small RNA and mRNA targets of Hfq

Hfq links translation repression to stress-induced mutagenesis in E. coli

Hfqs in Bacillus anthracis: Role of protein sequence variation in the structure and function of proteins in the Hfq family ⬇️

Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis

IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein

In vivo characterization of an Hfq protein encoded by the Bacillus anthracis virulence plasmid pXO1 ⬇️

Integrating anaerobic/aerobic sensing and the general stress response through the ArcZ small RNA

Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system

Mechanism of positive regulation by DsrA and RprA small noncoding RNAs: pairing increases translation and protects rpoS mRNA from degradation

Meeting report: Regulating with RNA in Bacteria 2013.

MicA sRNA links the PhoP regulon to cell envelope stress

Micros for microbes: non-coding regulatory RNAs in bacteria

Modes of regulation of RpoS by H-NS

Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli

Modulating the outer membrane with small RNAs

Multiple in vivo roles for the C-terminal domain of the RNA chaperone Hfq

Multiple pathways for regulation of sigmaS (RpoS) stability in Escherichia coli via the action of multiple anti-adaptors

Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets

New aspects of RNA-based regulation by Hfq and its partner sRNAs

Not just Salk

Overproduction of the Lon protease triggers inhibition of translation in Escherichia coli: involvement of the yefM-yoeB toxin-antitoxin system

Positive regulation by small RNAs and the role of Hfq

Proteolysis in Bacterial Regulatory Circuits ⬇️

RNA reflections: converging on Hfq

RNase E finds some sRNAs stimulating

Regulating the regulator: an RNA decoy acts as an OFF switch for the regulation of an sRNA.

Regulation and mode of action of the second small RNA activator of RpoS translation, RprA

Regulation of acetate metabolism and coordination with the TCA cycle via a processed small RNA

Regulatory roles for small RNAs in bacteria ⬇️

Remodelling of the Escherichia coli outer membrane by two small regulatory RNAs

Role of RcsF in signaling to the Rcs phosphorelay pathway in Escherichia coli

Role of polynucleotide phosphorylase in sRNA function in Escherichia coli

Roles of adaptor proteins in regulation of bacterial proteolysis

SigmaE regulates and is regulated by a small RNA in Escherichia coli

Small RNA Regulation of TolC, the Outer Membrane Component of Bacterial Multidrug Transporters

Small RNAs shed some light

Spot 42 sRNA regulates arabinose-inducible araBAD promoter activity by repressing synthesis of the high-affinity low-capacity arabinose transporter

Stealth regulation: biological circuits with small RNA switches

Stress Reduction, Bacterial Style

Stress sigma factor RpoS degradation and translation are sensitive to the state of central metabolism

Structural basis for inhibition of a response regulator of σS stability by a ClpXP antiadaptor

The 5' end of two redundant sRNAs is involved in the regulation of multiple targets, including their own regulator

The Crp-activated small noncoding regulatory RNA CyaR (RyeE) links nutritional status to group behavior

The MiaA tRNA modification enzyme is necessary for robust RpoS expression in Escherichia coli

The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica

The Rcs phosphorelay: a complex signal transduction system

The RpoS-mediated general stress response in Escherichia coli

The novel transcription factor SgrR coordinates the response to glucose-phosphate stress

Translational regulation of the Escherichia coli stress factor RpoS: a role for SsrA and Lon

Unexpected properties of sRNA promoters allow feedback control via regulation of a two-component system ⬇️

ppGpp regulation of RpoS degradation via anti-adaptor protein IraP.

sRNA roles in regulating transcriptional regulators: Lrp and SoxS regulation by sRNAs

sRNA-Mediated Control of Transcription Termination in E. coli