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List of works by Jane A. McKeating

1566. Is Primary CMV Infection Post-transplant Influenced by Circadian Rhythms?

article published in 2018

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort.

scientific article

A PCR assay to quantify patterns of HBV transcription

scientific article published on 17 December 2019

A bile acid transporter as a candidate receptor for hepatitis B and D virus entry

scientific article published on 8 February 2013

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

scientific article published on 27 March 2019

A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration

scientific article

A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81.

scientific article published on 7 September 2017

A role for CD81 and hepatitis C virus in hepatoma mobility

scientific article published on 24 March 2014

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

scientific article published on 20 January 2022

Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

scientific article published on 03 March 2020

Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner.

scientific article published on 25 February 2014

Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant

scientific article published on 20 May 2015

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

scientific article

An immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 (HXB2-Env:Ala 582(-->Thr)) decreases viral neutralization by monoclonal antibodies to the CD4-binding site

scientific article published on September 1993

Antigenic variation within the CD4 binding site of human immunodeficiency virus type 1 gp120: effects on chemokine receptor utilization

scientific article

Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models

scientific article published on 03 November 2020

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

scientific article published on 23 January 2017

Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway

scientific article published on 27 May 2019

Binding of hepatitis C virus E2 glycoprotein to CD81 does not correlate with species permissiveness to infection

scientific article

Binding of the hepatitis C virus E2 glycoprotein to CD81 is strain specific and is modulated by a complex interplay between hypervariable regions 1 and 2.

scientific article

Bioportide: an emergent concept of bioactive cell-penetrating peptides

scientific article published on 20 April 2012

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

scientific article published on 6 December 2007

CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry

scientific article

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

scientific article

Characterization of HIV-1 neutralization escape mutants

scientific article

Characterization of infectious retroviral pseudotype particles bearing hepatitis C virus glycoproteins

scientific article

Chimeric viruses expressing primary envelope glycoproteins of human immunodeficiency virus type I show increased sensitivity to neutralization by human sera.

scientific article published in June 1996

Cholesterol-modifying drugs in COVID-19

scientific article published on 18 June 2020

Claudin association with CD81 defines hepatitis C virus entry.

scientific article

Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry

scientific article

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

scientific article published on 23 March 2015

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses

scientific article

Complete replication of hepatitis C virus in cell culture

scientific article (publication date: 22 July 2005)

Correction to 'Viral hepatitis and liver cancer'.

scientific article published in January 2018

Daytime variation in hepatitis C virus replication kinetics following liver transplant

scientific article published on 20 September 2018

Deep sequencing of hepatitis C virus reveals genetic compartmentalization in cerebrospinal fluid from cognitively impaired patients.

scientific article published on 5 April 2016

Detection of cytomegalovirus in urine samples by enzyme-linked immunosorbent assay

scientific article published on 01 August 1985

Development of novel therapies for hepatitis C.

scientific article published on April 2010

Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission.

scientific article published on 21 October 2013

Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

scientific article published on 29 November 2006

Diverse CD81 Proteins Support Hepatitis C Virus Infection

scientific article (publication date: November 2006)

Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner

scientific article published on August 2004

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

scientific article published on 24 April 2011

Early infection events highlight the limited transmissibility of hepatitis C virus in vitro.

scientific article published on 23 January 2013

Editorial overview - virus entry: towards reality - refining models of virus entry

scientific article published on 31 January 2014

Effect of Cell Polarization on Hepatitis C Virus Entry

scientific article (publication date: 2008)

Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture

scientific article

Enhancement of class I HLA antigen expression by cytomegalovirus: role in amplification of virus infection

scientific article

Entry of hepatitis B and C viruses - recent progress and future impact.

scientific article published on 14 January 2014

Expression of DC-SIGN and DC-SIGNR on Human Sinusoidal Endothelium

scientific article

Expression of HIV-1 envelope glycoproteins by Semliki Forest virus vectors.

scientific article published in October 1993

Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies.

scientific article published on 17 July 2013

Functional characterization of intracellular and secreted forms of a truncated hepatitis C virus E2 glycoprotein

scientific article

Functional characterization of the V1V2 region of human immunodeficiency virus type 1.

scientific article published in June 1996

Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization. ⬇️

scientific article published on 29 August 2017

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen

article

HIV infactivity

scientific article published in Nature

HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.

scientific article published on March 2013

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels

scientific article published on 22 August 2018

Hepatitis C Virus (HCV)–Specific Immune Responses of Long‐Term Injection Drug Users Frequently Exposed to HCV

scientific article (publication date: 15 July 2008)

Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function

scientific article published on 12 April 2007

Hepatitis C virus and alanine aminotransferase kinetics following B-lymphocyte depletion with rituximab: evidence for a significant role of humoral immunity in the control of viremia in chronic HCV liver disease

scientific article published in January 2007

Hepatitis C virus and the brain.

scientific article published on May 2012

Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cells

scientific article (publication date: 15 January 2009)

Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies

scientific article published in January 2008

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

scientific article published on 3 December 2006

Hepatitis C virus entry and neutralization

scientific article published on August 2008

Hepatitis C virus entry and the tetraspanin CD81.

scientific article published on April 2011

Hepatitis C virus entry: beyond receptors

scientific article published on 06 March 2012

Hepatitis C virus entry: possible targets for therapy

scientific article published on December 2008

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

scientific article

Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies

scientific article published on 14 September 2007

Hepatitis C virus glycoprotein E2 binding to CD81: the role of E1E2 cleavage and protein glycosylation in bioactivity

scientific article published on July 2000

Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR

scientific article

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

scientific article

Hepatitis C virus induces CD81 and claudin-1 endocytosis

scientific article

Hepatitis C virus infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure

scientific article published on 17 January 2019

Hepatitis C virus infection of cholangiocarcinoma cell lines.

scientific article

Hepatitis C virus infection of neuroepithelioma cell lines

scientific article published on 9 June 2010

Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner

scientific article published on 26 November 2009

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

scientific article published on December 2011

Hepatitis C virus receptor expression in normal and diseased liver tissue

scientific article published on February 2008

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

scientific article published on 2 May 2011

Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization

scientific article (publication date: December 2009)

Hepatoma polarization limits CD81 and hepatitis C virus dynamics

scientific article

Heterogeneous claudin-1 expression in human liver

scientific article published on February 2013

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease. ⬇️

scientific article

Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

scientific article

Humoral immune response in acute hepatitis C virus infection

scientific article

Hypoxia inducible factors in liver disease and hepatocellular carcinoma: current understanding and future directions.

scientific article

Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models

scientific article published on 24 August 2020

Hypoxic microenvironment shapes HIV-1 replication and latency

scientific article published on 14 July 2020

IFITM1 is a tight junction protein that inhibits hepatitis C virus entry

scientific article published on 12 December 2012

IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria

scientific article

Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies

scientific article (publication date: December 2008)

Identification of a monoclonal antibody to abscission tissue that recognises xylose/fucose-containing N-linked oligosaccharides from higher plants

scientific article published on October 1988

Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants

scientific article

Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2.

scientific article

Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains

scientific article published on 25 July 2011

Immunogenicity of full length and truncated forms of the human immunodeficiency virus type I envelope glycoprotein.

scientific article published in June 1996

In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface

scientific article published on 25 September 2012

In vitro selection of a neutralization-resistant hepatitis C virus escape mutant

scientific article

In vitro veritas? The challenges of studying hepatitis C virus infectivity in a test tube

scientific article published on 19 December 2006

Inflammatory Gene Expression Associates with Hepatitis B Virus cccDNA- but Not Integrant-Derived Transcripts in HBeAg Negative Disease

scientific article published on 17 May 2022

Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-claudin-1 associations

scientific article published in April 2010

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I

scientific article

Insights From Deep Sequencing of the HBV Genome-Unique, Tiny, and Misunderstood

scientific article published on 27 September 2018

Interplay between circadian clock and viral infection.

scientific article published on 30 September 2017

Lentiviral hepatitis B pseudotype entry requires sodium taurocholate co-transporting polypeptide and additional hepatocyte-specific factors

scientific article published on 16 October 2015

Mechanisms of viral entry: sneaking in the front door

scientific article

Metallo supramolecular cylinders inhibit HIV-1 TAR-TAT complex formation and viral replication in cellulo

scientific article published in Scientific Reports

Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes

scientific article published on 2 June 2010

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

scientific article published on 28 December 2015

Monoclonal antibodies to the C4 region of human immunodeficiency virus type 1 gp120: use in topological analysis of a CD4 binding site

scientific article published on April 1, 1992

Multidrug treatment with nelfinavir and cepharanthine against COVID-19

scientific article published on 16 April 2020

Multiple effects of silymarin on the hepatitis C virus lifecycle

scientific article

Mutant CD4 molecules with improved binding to HIV envelope protein gp120 selected by phage display

scientific article published on August 1997

Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity

scientific article (publication date: June 2009)

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

scientific article

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

scientific article (publication date: March 2012)

Neutralizing antibody response during acute and chronic hepatitis C virus infection

scholarly article

Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission

scientific article published on 20 October 2010

Over the fence or through the gate: how viruses infect polarized cells

scientific article published on 01 March 2012

Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells

scientific article published in May 2006

Oxygen Sensing and Viral Replication: Implications for Tropism and Pathogenesis

scientific article published on 25 October 2020

Paracrine signals from liver sinusoidal endothelium regulate hepatitis C virus replication

scientific article published on 18 December 2013

Passage of HIV-1 molecular clones into different cell lines confers differential sensitivity to neutralization

scientific article

Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection.

scientific article

Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

scientific article

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

scientific article published on 06 August 2020

Pharmacological characterization of the chemokine receptor, CCR5.

scientific article published in February 2002

Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

scientific article

Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation ⬇️

scientific article published on 17 March 2014

Primary hepatocytes as targets for hepatitis C virus replication

scientific article published on December 2008

Production, purification and characterization of recombinant, full-length human claudin-1.

scientific article

Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity

scientific article

Rituximab treatment in hepatitis C infection: an in vitro model to study the impact of B cell depletion on virus infectivity

scientific article published on 30 September 2011

Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity

scientific article

Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent

scientific article (publication date: 2008)

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

scientific article published on April 1999

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

scientific article published on 21 August 2010

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes ⬇️

scientific article (publication date: 25 October 2016)

Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes

scientific article published on April 2011

Structural characterization of recombinant human CD81 produced in Pichia pastoris

scientific article published on 24 October 2007

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.

scientific article

Structure and function of the HIV envelope

scientific article published on January 1989

Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus

scientific article

Superinfection Exclusion in Cells Infected with Hepatitis C Virus

scientific article (publication date: April 2007)

Synchronized infection identifies early rate-limiting steps in the hepatitis B virus life cycle

scientific article published on 16 August 2020

TNF superfamily members promote hepatitis C virus entry via an NF-κB and myosin light chain kinase dependent pathway.

scientific article published on 15 December 2016

The CCCTC-binding factor CTCF represses hepatitis B virus Enhancer I and regulates viral transcription

scientific article published on 01 October 2020

The Circadian Clock and Viral Infections

scientific article published on 09 November 2020

The Effect of Low-Profile Serine Substitutions in the V3 Loop of HIV-1 gp120 IIIB/LAI on the Immunogenicity of the Envelope Protein

article

The Involvement of Tight Junction Protein Claudin-1 in Hepatitis C Virus Entry

article

The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis.

scientific article published on 18 January 2017

The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein

scientific article

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

scientific article published in Nature Communications

The complexities of hepatitis C virus entry

scientific article published on 2 July 2009

The past, present and future of neutralizing antibodies for hepatitis C virus

scientific article published on 26 February 2014

The role of the hepatitis C virus glycoproteins in infection.

scientific article

The role of the viral glycoprotein in HIV-1 persistence.

scientific article

Time of Day of Vaccination Affects SARS-CoV-2 Antibody Responses in an Observational Study of Health Care Workers

scientific article published in 2021

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

scientific article (publication date: February 2006)

Type I interferon rapidly restricts infectious hepatitis C virus particle genesis.

scientific article

Viral hepatitis and liver cancer.

scientific article published on October 2017

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