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List of works by Mark Lautens

A New Multicomponent Multicatalyst Reaction (MC)(2)R: Chemoselective Cycloaddition and Latent Catalyst Activation for the Synthesis of Fully Substituted 1,2,3-Triazoles

scientific article published on 23 May 2016

A conjunctive carboiodination: indenes by a double carbopalladation-reductive elimination domino process

scientific article published on 03 September 2012

A convergent synthesis of polysubstituted aromatic nitriles via palladium-catalyzed C-H functionalization.

scientific article published on 17 November 2007

A general and practical method of alkynyl indole and benzofuran synthesis via tandem Cu- and Pd-catalyzed cross-couplings

scientific article published on 27 June 2007

A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins

scientific article published on 09 June 2007

A highly efficient and selective route to isomeric cyclic diazadienes

scientific article published on 01 February 2007

A palladium-catalyzed alkylation/direct arylation synthesis of nitrogen-containing heterocycles

scientific article published on 09 February 2008

A palladium-catalyzed approach to polycyclic sulfur heterocycles

scientific article published on 18 October 2008

A rapid approach to the synthesis of highly functionalized tetrahydroisoquinolines

scientific article published on 01 February 2009

A rhodium IBiox[(-)-menthyl] complex as a highly selective catalyst for the asymmetric hydroarylation of azabicyles: an alternative route to epibatidine.

scientific article published in July 2010

A simple, cost-effective method for the regioselective deuteration of anilines

scientific article published on 30 August 2008

A tandem catalytic approach to methyleneindenes: mechanistic insights into gem-dibromoolefin reactivity.

scientific article published in June 2010

Addition of arylboronic acids to arylpropargyl alcohols en route to indenes and quinolines

scientific article published on 14 September 2011

Additive effects in the palladium-catalyzed carboiodination of chiral N-allyl carboxamides

scientific article published on 10 June 2014

Allenylic Carbonates in Enantioselective Iridium-Catalyzed Alkylations

scientific article published on 22 March 2018

Aminomethylation of Oxabenzonorbornadienes via the Merger of Photoredox and Nickel Catalysis

scientific article published on 02 March 2020

An Exclusivelytrans-Selective Chlorocarbamoylation of Alkynes Enabled by a Palladium/Phosphaadamantane Catalyst

scientific article published on 20 November 2015

Application of a rhodium-catalyzed addition/cyclization sequence toward the synthesis of polycyclic heteroaromatics.

scientific article published in February 2009

Application of secondary alkyl halides to a domino aryl alkylation reaction for the synthesis of aromatic heterocycles

scientific article published on 01 January 2009

Aromatic ortho-benzylation reveals an unexpected reductant

scientific article published on 08 October 2008

Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.

scientific article published on January 2007

Benzylic Functionalization of Anthrones via the Asymmetric Ring Opening of Oxabicycles Utilizing a Fourth-Generation Rhodium Catalytic System.

scientific article published on 27 August 2015

Bifunctional reactivity of Cu(I): sequential ring opening/N-arylation

scientific article published on 01 January 2009

C-H bond functionalization in the synthesis of fused 1,2,3-triazoles

scientific article published on 14 October 2010

Carboiodination Catalyzed by Nickel

scientific article published on 23 August 2018

Chemodivergence in enantioselective desymmetrization of diazabicycles: ring-opening versus reductive arylation

scientific article published on 01 January 2008

Combining Ru-Catalyzed C-H Functionalization with Pd-Catalyzed Asymmetric Allylic Alkylation: Synthesis of 3-Allyl-3-aryl Oxindole Derivatives from Aryl α-Diazoamides

scientific article published on 15 September 2016

Computational and ¹³C investigations of the diazadienes and oxazadienes formed via the rearrangement of methylenecyclopropyl hydrazones and oximes

scientific article published on 22 July 2014

Concise enantioselective total syntheses of (+)-homochelidonine, (+)-chelamidine, (+)-chelidonine, (+)-chelamine and (+)-norchelidonine by a Pd II-catalyzed ring-opening strategy.

scientific article

Conformational effects in diastereoselective aryne Diels-Alder reactions: synthesis of benzo-fused [2.2.1] heterobicycles

scientific article published on 01 October 2009

Construction of nitrogen-containing heterocycles by C-H bond functionalization

scientific article published on 01 June 2009

Convenient access to functionalized vinylcyclopentenols from alkynyloxiranes

scientific article published on 07 February 2007

Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols

scientific article published on 07 March 2019

Dearomative Indole Bisfunctionalization via a Diastereoselective Palladium-Catalyzed Arylcyanation

scientific article published on 01 October 2015

Diastereoselective Friedel-Crafts alkylation of hydronaphthalenes

scientific article published on 05 October 2011

Diastereoselective Nickel-Catalyzed Carboiodination Generating Six-Membered Nitrogen-Based Heterocycles

scientific article published on 21 August 2019

Diastereoselective intramolecular Friedel-Crafts alkylation of tetralins

scientific article published on 18 May 2011

Diastereoselective palladium-catalyzed arylcyanation/heteroarylcyanation of enantioenriched N-allylcarboxamides

scientific article published on 02 December 2014

Discovery of mu-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions.

scientific article

Domino rhodium-catalyzed alkyne arylation/palladium-catalyzed N arylation: a mechanistic investigation

scientific article published on 24 August 2011

Efficient syntheses of KDR kinase inhibitors using a Pd-catalyzed tandem C-N/Suzuki coupling as the key step

scientific article published on 25 January 2007

Enantioselective Copper-Catalyzed Borylative Cyclization with Cyclic Imides

scientific article published on 01 October 2019

Enantioselective Intramolecular Copper-Catalyzed Borylacylation

scientific article published on 21 September 2018

Enantioselective Rh-catalyzed domino transformations of alkynylcyclohexadienones with organoboron reagents

scientific article published on 20 February 2013

Enantioselective catalytic ring expansion of methylenecyclopropane carboxamides promoted by a chiral magnesium Lewis acid

scientific article published on 25 January 2007

Enantioselective palladium-catalyzed carbozincation of cyclopropenes

scientific article published on 20 January 2011

Enantioselective total synthesis of (+)-homochelidonine by a PdII-catalyzed asymmetric ring-opening reaction of a meso-azabicyclic alkene with an aryl boronic acid

scientific article published on 01 January 2007

Expanding the Scope of the Gold(I)-Catalyzed Rautenstrauch Rearrangement: Protic Additives

scientific article published on 23 September 2016

Expedient synthesis of chiral oxazolidinone scaffolds via rhodium-catalyzed asymmetric ring-opening with sodium cyanate

scientific article published on 08 February 2013

Expeditious synthesis of tetrasubstituted helical alkenes by a cascade of palladium-catalyzed C-H activations

scientific article published on 24 August 2012

Exploiting Distal Reactivity of Coumarins: A Rhodium-Catalyzed Vinylogous Asymmetric Ring-Opening Reaction.

scientific article published on 4 March 2016

Exploiting the chemistry of strained rings: synthesis of indoles via domino reaction of aryl iodides with 2H-azirines.

scientific article published in August 2010

Exploring the mechanism of the Pd-catalyzed spirocyclization reaction: a combined DFT and experimental study.

scientific article published on 8 December 2017

Formal synthesis of nitidine and NK109 via palladium-catalyzed domino direct arylation/N-arylation of aryl triflates

scientific article published on 24 February 2011

Forming Benzylic Iodides via a Nickel Catalyzed Diastereoselective Dearomative Carboiodination Reaction of Indoles

scientific article published on 12 March 2019

Functionalized chromans and isochromans via a diastereoselective Pd(0)-catalyzed carboiodination

scientific article published on 06 September 2012

Gast Editorial: Celebrating Canadian Chemistry.

scientific article published on 24 April 2017

Gold meets rhodium: tandem one-pot synthesis of β-disubstituted ketones via Meyer-Schuster rearrangement and asymmetric 1,4-addition

scientific article published on 18 June 2013

Identification and Structure–Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors

scientific article published on 09 May 2018

Intermolecular domino reaction of two aryl iodides involving two C-H functionalizations

scientific article published on 03 April 2014

Intramolecular Copper(I)-Catalyzed Interrupted Click-Acylation Domino Reaction

scientific article published on 07 August 2019

Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles.

scientific article published on 6 August 2009

Iridium-Catalyzed Asymmetric Synthesis of Functionally Rich Molecules Enabled by (Phosphoramidite,Olefin) Ligands

scientific article published on 19 June 2019

Ligand-controlled selectivity in the desymmetrization of meso cyclopenten-1,4-diols via rhodium(I)-catalyzed addition of arylboronic acids

scientific article published on 01 June 2010

Linear-selective rhodium(I)-catalyzed addition of arylboronic acids to allyl sulfones.

scientific article published on November 2010

Mechanistic insights on the Pd-catalyzed addition of C-X bonds across alkynes - a combined experimental and computational study

scientific article published on 27 January 2017

Mechanistic studies of Pd-catalyzed regioselective aryl C-H bond functionalization with strained alkenes: origin of regioselectivity

scientific article published on 03 June 2011

Metal-Catalyzed Approaches toward the Oxindole Core

scientific article published on 24 July 2020

Metal-ligand binding affinity vs reactivity: qualitative studies in Rh(I)-catalyzed asymmetric ring-opening reactions

scientific article published on 17 May 2013

Metal-ligand binding interactions in rhodium/palladium-catalyzed synthesis of dihydroquinolines

scientific article published on 07 November 2014

Modern Transition-Metal-Catalyzed Carbon-Halogen Bond Formation

scientific article published on 24 June 2016

Modular and stereoselective synthesis of tetrasubstituted helical alkenes via a palladium-catalyzed domino reaction

scientific article published on 27 June 2012

Modular synthesis of naphthothiophenes by Pd-catalyzed tandem direct arylation/Suzuki coupling

scientific article published on 27 July 2011

Multicomponent multicatalyst reactions (MC)2R: one-pot synthesis of 3,4-dihydroquinolinones

scientific article published on 19 April 2013

Multicomponent-multicatalyst reactions (MC)(2)R: efficient dibenzazepine synthesis.

scientific article

Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles

scientific article published on 29 June 2018

One-pot synthesis of chiral dihydrobenzofuran framework via Rh/Pd catalysis

scientific article published on 12 October 2012

Organoselenium-catalyzed mild dehydration of aldoximes: an unexpected practical method for organonitrile synthesis

scientific article published on 24 February 2014

Palladium(II)-Catalyzed Enantioselective Synthesis of α-(Trifluoromethyl)arylmethylamines

scientific article published on 01 June 2016

Palladium(II)-catalyzed enantioselective synthesis of α-(trifluoromethyl)arylmethylamines

scientific article published on 24 July 2013

Palladium-Catalyzed Arylation/Heteroarylation of Indoles: Access to 2,3-Functionalized Indolines

scientific article published on 07 November 2018

Palladium-Catalyzed Disilylation and Digermanylation of Alkene Tethered Aryl Halides: Direct Access to Versatile Silylated and Germanylated Heterocycles

scientific article published on 20 April 2020

Palladium-Catalyzed Hydride Addition/C-H Bond Activation Cascade: Cycloisomerization of 1,6-Diynes

article

Palladium-Catalyzed Hydrohalogenation of 1,6-Enynes: Hydrogen Halide Salts and Alkyl Halides as Convenient HX Surrogates.

scientific article

Palladium-Catalyzed Norbornene-Mediated Tandem Amination/Cyanation Reaction: A Method for the Synthesis of ortho-Aminated Benzonitriles

scientific article published on 23 August 2016

Palladium-Catalyzed Spirocyclization through C-H Activation and Regioselective Alkyne Insertion

scientific article published on 14 July 2017

Palladium-Catalyzed Synthesis of 2-Cyanoindoles from 2-gem-Dihalovinylanilines.

scientific article published on 13 September 2017

Palladium-Catalyzed Synthesis of Dihydrobenzoindolones via C-H Bond Activation and Alkyne Insertion

scientific article published on 05 July 2018

Palladium-Catalyzed α-Arylation of Vinylogous Esters for the Synthesis of γ,γ-Disubstituted Cyclohexenones.

scientific article

Palladium-Catalyzed, Norbornene-Mediated, ortho-Amination ipso-Amidation: Sequential C-N Bond Formation

scientific article published on 28 December 2017

Palladium-catalysed norbornene-mediated C-H functionalization of arenes.

scientific article published on October 2015

Palladium-catalyzed annulation of aryl heterocycles with strained alkenes

scientific article published on 04 April 2007

Palladium-catalyzed annulation of haloanilines and halobenzamides using norbornadiene as an acetylene synthon: a route to functionalized indolines, isoquinolinones, and indoles.

scientific article published in February 2009

Palladium-catalyzed carbohalogenation: bromide to iodide exchange and domino processes

scientific article published on 06 September 2011

Palladium-catalyzed carboiodination of alkenes: carbon-carbon bond formation with retention of reactive functionality

scientific article published on 25 January 2011

Palladium-catalyzed domino C-C/C-N coupling using a norbornene template: synthesis of substituted benzomorpholines, phenoxazines, and dihydrodibenzoxazepines

scientific article

Palladium-catalyzed domino direct arylation/N-arylation: convenient synthesis of phenanthridines

scientific article published on 01 January 2009

Pd(0)-Catalyzed Dearomative Diarylation of Indoles

scientific article

Pd-Catalyzed Spirocyclization via C-H Activation and Benzyne Insertion

scientific article published on 01 December 2016

Practical asymmetric synthesis of bioactive aminotetralins from a racemic precursor using a regiodivergent resolution.

scientific article published on 2 November 2010

Reagent-controlled regiodivergent resolution of unsymmetrical oxabicyclic alkenes using a cationic rhodium catalyst.

scientific article published in January 2009

Remote C-H alkylation and C-C bond cleavage enabled by an in situ generated palladacycle

scientific article published on 17 October 2016

Rh(I)-catalyzed carbonylative ring opening of diazabicycles with acyl anion equivalents

scientific article published on 17 November 2007

Rh(I)-catalyzed ring-opening of hetaryne-furan Diels-Alder adducts: rapid access to stereochemically defined heterocyclic scaffolds

scientific article published on 24 February 2011

Rh-Catalyzed Domino Addition-Enolate Arylation: Generation of 3-Substituted Oxindoles via a Rh(lll) Intermediate

scientific article published on 09 July 2015

Rh/Pd catalysis with chiral and achiral ligands: domino synthesis of aza-dihydrodibenzoxepines

scientific article published on 19 July 2013

Rhodium(I)-catalyzed addition of arylboronic acids to (benzyl-/arylsulfonyl)acetonitriles: efficient synthesis of (Z)-β-sulfonylvinylamines and β-keto sulfones

scientific article published on 13 December 2010

Rhodium(I)-catalyzed cyclization reaction of o-alkynyl phenols and anilines. Domino approach to 2,3-disubstituted benzofurans and indoles

scientific article published on 01 March 2009

Rhodium-Catalyzed Asymmetric Conjugate Alkynylation/Aldol Cyclization Cascade for the Formation of α-Propargyl-β-hydroxyketones.

scientific article published on 9 February 2018

Rhodium-Catalyzed Asymmetric Cycloisomerization and Parallel Kinetic Resolution of Racemic Oxabicycles

scientific article

Rhodium-Catalyzed Enantioselective Defluorinative α-Arylation of Secondary Amides

scientific article published on 08 November 2018

Rhodium-Catalyzed Enantioselective Isomerization of meso-Oxabenzonorbornadienes to 1,2-Naphthalene Oxides.

scientific article

Rhodium-Catalyzed Enantioselective Reductive Arylation: Convenient Access to 3,3-Disubstituted Oxindoles

scientific article published on 13 July 2017

Rhodium-Catalyzed Enantioselective Synthesis of Oxazinones via an Asymmetric Ring Opening-Lactonization Cascade of Oxabicyclic Alkenes

scientific article published on 06 September 2019

Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening

scientific article published on 04 June 2020

Rhodium-catalyzed arylative cyclization for the enantioselective synthesis of (trifluoromethyl)cyclobutanols

scientific article published on 18 September 2014

Rhodium-catalyzed domino enantioselective synthesis of bicyclo[2.2.2]lactones

scientific article published on 22 June 2011

Rhodium-catalyzed enantioselective nucleophilic fluorination: ring opening of oxabicyclic alkenes

scientific article published on 04 November 2012

Rhodium-catalyzed vinylcyclopropanation/cyclopentenation of strained alkenes via a sequential carborhodation process.

scientific article published in March 2009

Secondary alkyl halides in transition-metal-catalyzed cross-coupling reactions.

scientific article

Sequential rhodium/palladium catalysis: enantioselective formation of dihydroquinolinones in the presence of achiral and chiral ligands

scientific article published on 24 September 2014

Silver-promoted domino Pd-catalyzed amination/direct arylation: access to polycyclic heteroaromatics

scientific article published on 19 September 2008

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin

scientific article

Stereochemical and mechanistic investigations of a palladium-catalyzed annulation of secondary alkyl iodides

scientific article published on 01 January 2007

Stereoselective Construction of γ-Lactams via Copper-Catalyzed Borylacylation

scientific article published on 29 September 2020

Stereoselective Synthesis of Methylene Oxindoles via Palladium(II)-Catalyzed Intramolecular Cross-Coupling of Carbamoyl Chlorides

scientific article published on 4 October 2016

Synergistic steric effects in the development of a palladium-catalyzed alkyne carbohalogenation: stereodivergent synthesis of vinyl halides

scientific article published on 06 November 2014

Synthesis and Reactions of 3,3-Difluoro-2-exo-methylidene Indolines

scientific article published on 10 April 2020

Synthesis in the key of Catellani: norbornene-mediated ortho C-H functionalization.

scientific article published on January 2010

Synthesis of 1,2,3-triazole-fused heterocycles via Pd-catalyzed cyclization of 5-iodotriazoles

scientific article published on 14 November 2011

Synthesis of 2-oxazolones and α-aminoketones via palladium-catalyzed reaction of β,β-dibromoenamides

scientific article published on 02 December 2010

Synthesis of Aminated Phenanthridinones via Palladium/Norbornene Catalysis

scientific article published on 29 September 2020

Synthesis of Pyridobenzazepines Using a One-Pot Rh/Pd-Catalyzed Process

scientific article

Synthesis of annulated 2H-indazoles and 1,2,3- and 1,2,4-triazoles via a one-pot palladium-catalyzed alkylation/direct arylation reaction.

scientific article

Synthesis of benzannulated N-heterocycles by a palladium-catalyzed C-C/C-N coupling of bromoalkylamines

scientific article published on 15 November 2007

Synthesis of beta,gamma-unsaturated lactams via a magnesium iodide promoted ring expansion of secondary methylenecyclopropyl amides

scientific article published on 01 November 2006

Synthesis of enantioenriched 5,6-dihydrophenanthridine derivatives through retro-carbopalladation of chiral o-bromobenzylamines

scientific article published on 08 January 2015

Synthesis of polycyclic benzonitriles via a one-pot aryl alkylation/cyanation reaction

scientific article published on 01 November 2006

Synthesis of polycyclic heterocycles via a one-pot ortho alkylation/direct heteroarylation sequence

scientific article published on 01 October 2006

Synthesis of tricyclic heterocycles via a tandem aryl alkylation/heck coupling sequence

scientific article published on 01 February 2007

The Role of Reversible Oxidative Addition in Selective Palladium(0)-Catalyzed Intramolecular Cross-Couplings of Polyhalogenated Substrates: Synthesis of Brominated Indoles ⬇️

scientific article published on August 25, 2010

The use of silyl ketene acetals and enol ethers in the catalytic enantioselective alkylative ring opening of oxa/aza bicyclic alkenes

scientific article published on 25 April 2014

Transition-Metal-Free [4+3]-Cycloaddition of ortho-Quinone Methides and Isomünchnones: Catalytic and Diastereoselective Assembly of Oxa-bridged Oxazocine Scaffolds

scientific article published on 12 November 2018

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