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List of works by Guido Kroemer

3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

scientific article published on 14 October 2019

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects

scientific article published on 28 June 2019

4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.

scientific article published on 23 November 2007

53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope

scientific article published on 30 October 2009

A Cytofluorometric Assay of Nuclear Apoptosis Induced in a Cell-Free System: Application to Ceramide-Induced Apoptosis

A Single Injection of Staphylococcus aureus Enterotoxin B Reduces Autoimmunity in MRL/lpr Mice

scientific article published on 01 May 1994

A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency

scientific article published on 12 October 2020

A bidirectional crosstalk between autophagy and TP53 determines the pace of aging

scientific article published on 18 June 2020

A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2

scientific article

A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.

scientific article

A cellular machine generating apoptosis-prone aneuploid cells.

scientific article published in January 2005

A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint

scientific article

A comprehensive glossary of autophagy-related molecules and processes

scientific article published on 16 May 2010

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

scientific article

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects

scientific article published on 07 November 2019

A dual role for autophagy in a murine model of lung cancer

scientific article published in Nature Communications

A dual role of p53 in the control of autophagy

scientific article

A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors

scientific article published on March 15, 2011

A fluorescence-microscopic and cytofluorometric system for monitoring the turnover of the autophagic substrate p62/SQSTM1.

scientific article published on August 2011

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers

scientific article published on 26 April 2019

A four-lane highway to cancer.

scientific article

A genome-wide RNA interference screen disentangles the Golgi tropism of LC3

scientific article published on 10 December 2020

A higher spirit: avoiding yeast suicide during alcoholic fermentation

scientific article published on June 1, 2012

A histone point mutation that switches on autophagy

scientific article published in June 2014

A human mitochondriopathy caused by AIF mutation

scientific article published on 01 October 2010

A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription

scientific article

A multiplicity of cell death pathways. Symposium on apoptotic and non-apoptotic cell death pathways

scientific article published on 27 July 2007

A novel dendritic cell subset involved in tumor immunosurveillance

scientific article published on 29 January 2006

A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts

scientific article

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib

scientific article

A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity

scientific article (publication date: 15 March 2004)

A novel platinum-based chemotherapeutic inducing immunogenic cell death

scientific article published on 15 February 2020

A novel source of tetraploid cancer cell precursors: telomere insufficiency links aging to oncogenesis

scientific article published on 30 August 2010

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR

scientific article published on April 2016

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.

scientific article published on 22 July 2016

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease

scientific article published on 29 November 2018

A phase I/II trial of Erlotinib in higher risk myelodysplastic syndromes and acute myeloid leukemia after azacitidine failure

scientific article published on 7 October 2014

A revolution in apoptosis: from a nucleocentric to a mitochondriocentric perspective

scientific article published on 01 September 1998

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

scientific article published in August 2001

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies

scientific article published on 19 August 2013

A strategy for poisoning cancer cell metabolism: Inhibition of oxidative phosphorylation coupled to anaplerotic saturation

scientific article published on 29 July 2019

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

scientific article published on 07 September 2019

A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever

scientific article published on 10 June 2019

A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

scientific article

A-RAF

ACBP is an appetite stimulator across phylogenetic barriers

scientific article published on 20 January 2020

AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis

scientific article published on February 2004

AIF deficiency compromises oxidative phosphorylation

scientific article

AIF-regulated oxidative phosphorylation supports lung cancer development

scientific article published on 27 May 2019

AIF: not just an apoptosis-inducing factor

scientific article

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity

scientific article published on 26 July 2018

ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis

scientific article published on 08 May 2013

ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

scientific article

ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy

scientific article published on 16 April 2013

Aberrant ketolysis fuels hepatocellular cancer progression

scientific article published on 20 September 2016

Abscopal but desirable: The contribution of immune responses to the efficacy of radiotherapy

scientific article published on July 2012

Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin

scientific article published on 3 March 2015

Acetyl coenzyme A: a central metabolite and second messenger

scientific article

Acetyl-coenzyme A: a metabolic master regulator of autophagy and longevity.

scientific article published on 15 May 2014

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

scientific article published on 15 November 2016

Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis

scientific article published on 17 November 2018

Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid

scientific article published in Journal of Biological Chemistry

Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

scientific article

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

scientific article (publication date: October 2009)

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

scientific article published on 01 December 2019

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

scientific article published on 15 August 2019

Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator

scientific article published on 06 January 2020

Acyl-CoA-binding protein (ACBP): the elusive 'hunger factor' linking autophagy to food intake

scientific article published on 24 September 2019

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

scientific article

Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery

scientific article published on 21 August 2009

Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437

scientific article published on November 15, 2001

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth

scientific article published on 30 November 2018

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

scientific article published on 01 April 2020

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

scientific article published on 27 August 2019

Alternative cell death mechanisms in development and beyond

scientific article

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

scientific article published on 8 May 2011

Amino acid deprivation promotes intestinal homeostasis through autophagy

scientific article published on 19 April 2016

Ammonia: a diffusible factor released by proliferating cells that induces autophagy

scientific article published on June 2010

An AIF orthologue regulates apoptosis in yeast

scientific article

An anti-apoptotic viral protein that recruits Bax to mitochondria

scientific article published on 5 March 2004

An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells

scientific article published on January 2013

An atypical caspase-independent death pathway for an immunogenic cancer cell line

scientific article published on September 2002

An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe

scientific article

An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy

scientific article published on 3 July 2014

An epigenetic modifier triggers therapeutic immune responses against breast cancer

scientific article published on 5 April 2017

An immunosurveillance mechanism controls cancer cell ploidy

scientific article

An inhibitor of cyclin-dependent kinases suppresses TLR signaling and increases the susceptibility of cancer patients to herpesviridae

scientific article published in January 2011

An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA<sub>A</sub> receptor

scientific article published on 18 April 2022

An unexpected link between immunogenic cell death and inhibition of gene transcription

scientific article published on 08 July 2020

Analysis of the immune-encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis

scientific article published in October 1990

Anti- and pro-tumor functions of autophagy

scientific article published on 21 January 2009

Anti-CTLA-4 immunotherapy: uncoupling toxicity and efficacy

article

Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1.

scientific article published in March 2004

Antiapoptotic activity of argon and xenon

scientific article published on 16 July 2013

Antibody-drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory properties

scientific article published on 09 February 2022

Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects

scientific article published on 01 December 2020

Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects

scientific article

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death.

scientific article published on 18 June 2018

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

scientific article published on 4 April 2013

Anticancer effects of anti-CD47 immunotherapy in vivo

scientific article published on 11 December 2018

Anticancer effects of imatinib via immunostimulation

scientific article published on 07 September 2011

Anticancer effects of the microbiome and its products

scientific article published on 22 May 2017

Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects

scientific article published on 20 July 2009

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

scientific article published on 5 November 2015

Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

scientific article

Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia

scientific article

Antitumor Benefits of Antiviral Immunity: An Underappreciated Aspect of Oncolytic Virotherapies

scientific article published on 20 December 2017

Apaf-1 Deficiency Causes Chromosomal Instability

scientific article published on 14 September 2007

Apoptosis and apoptosis-associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long-term non-progressors

scientific article published in December 2000

Apoptosis and cell cycle: distinct checkpoints with overlapping upstream control.

scientific article

Apoptosis and genomic instability

scientific article published in September 2004

Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex

scientific article published on 01 November 2000

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

scientific article

Apoptosis in yeast: triggers, pathways, subroutines

scientific article published on 15 January 2010

Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione

scientific article

Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

scientific article

Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target.

scientific article published in February 2001

Apoptosis inversely correlates with rabies virus neurotropism.

scientific article published on December 2003

Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size

scientific article published in November 2000

Apoptosis regulation in tetraploid cancer cells

scientific article

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.

scientific article published on May 1996

Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

scientific article

Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis

scientific article (publication date: 7 July 2000)

Apoptosis-inducing factor (AIF): caspase-independent after all.

scientific article published in June 2004

Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

scientific article

Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation

scientific article

Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas

scientific article published on August 2004

Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.

scientific article published on 13 October 2006

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

scientific article

Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus

scientific article

Apoptosis-inducing factor: vital and lethal

scientific article

Apoptosis. Mitochondria--the death signal integrators

scientific article published on 01 August 2000

Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?

scientific article

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

scientific article

Apoptotic cell death in disease—Current understanding of the NCCD 2023

scientific article published in 2023

Arsenic trioxide, a novel mitochondriotoxic anticancer agent?

scientific article published on 01 May 1999

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

scientific article published on 01 June 1999

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy

scientific article published on 10 October 2019

Aspirin Recapitulates Features of Caloric Restriction

scientific article published in February 2018

Aspirin induces autophagy via inhibition of the acetyltransferase EP300.

scientific article published on 15 May 2018

Aspirin-another caloric-restriction mimetic

scholarly article by Federico Pietrocola published in July 2018

Assessment of Glycolytic Flux and Mitochondrial Respiration in the Course of Autophagic Responses

scientific article published on 23 November 2016

Assessment of annexin A1 release during immunogenic cell death

scientific article published on 02 July 2019

Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study

scientific article published on 16 May 2011

Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies

scientific article published on 01 August 1992

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer

scientific article published on 17 April 2019

Author Correction: IMMP2L: a mitochondrial protease suppressing cellular senescence.

scientific article

Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

scientific article published on 03 April 2019

Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

scientific article published on 01 September 2018

Autocrine signaling of type 1 interferons in successful anticancer chemotherapy

scientific article

Automated Analysis of Fluorescence Colocalization: Application to Mitophagy

scientific article published on 23 November 2016

Autophagic cell death: the story of a misnomer

scientific article (publication date: December 2008)

Autophagic removal of micronuclei

scientific article

Autophagy Mediates Tumor Suppression via Cellular Senescence

scientific article published on 20 November 2015

Autophagy Mediates the Metabolic Benefits of Endurance Training

scientific article published on May 11, 2012

Autophagy and Aging

scientific article (publication date: 2 September 2011)

Autophagy and Mitophagy in Cardiovascular Disease

scientific article

Autophagy and cellular immune responses

scientific article published on August 2013

Autophagy and innate immunity ally against bacterial invasion

scientific article published on 22 July 2011

Autophagy and the Integrated Stress Response

scientific article (publication date: 22 October 2010)

Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens.

scientific article

Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease

article

Autophagy extends lifespan via vacuolar acidification

scientific article published on 05 May 2014

Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease

scientific article

Autophagy for the avoidance of neurodegeneration

scientific article published on October 2009

Autophagy for tissue homeostasis and neuroprotection

scientific article published on 26 October 2010

Autophagy in Cardiovascular Aging

scientific article published on 01 September 2018

Autophagy in Ras-Induced Malignant Transformation: Fatal or Vital?

scientific article published on 01 April 2011

Autophagy in acute brain injury

scientific article published on 3 June 2016

Autophagy in aging, disease and death: the true identity of a cell death impostor

scientific article published on January 2009

Autophagy in hepatic adaptation to stress

scientific article published on 01 January 2020

Autophagy in malignant transformation and cancer progression

scientific article

Autophagy in natural and therapy-driven anticancer immunosurveillance

scientific article

Autophagy in non-small cell lung carcinogenesis: A positive regulator of antitumor immunosurveillance

scientific article

Autophagy in stress and disease

scientific article published in March 2015

Autophagy in the Pathogenesis of Disease

scientific article (publication date: 11 January 2008)

Autophagy in the cancer-immunity dialogue

scientific article published on 07 December 2020

Autophagy induction by thiostrepton for the improvement of anticancer therapy

scientific article published on 24 April 2020

Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy

scientific article published on 01 March 2020

Autophagy induction for the treatment of cancer

scientific article published on 17 August 2016

Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling

scientific article published on 13 September 2013

Autophagy is required for the activation of NFκB.

scientific article

Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol

scientific article

Autophagy regulation by p53.

scientific article published on 13 January 2010

Autophagy represses hepatic carcinogenesis

scientific article published on 13 May 2019

Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis

scholarly article by Valeria R Villella et al published 15 March 2019 in Cell Death and Disease

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

scientific article published on 20 February 2009

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

scientific article published on 15 July 2019

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

scientific article published on 01 January 2018

Autophagy, fitness and longevity

scientific article published on March 2017

Autophagy-Dependent Ferroptosis: Machinery and Regulation

scientific article published on 03 March 2020

Autophagy-dependent ATP release from dying cells via lysosomal exocytosis

scientific article published on 13 August 2013

Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

scientific article (publication date: 16 December 2011)

Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors

scientific article published on 10 December 2016

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

scientific article published on 16 January 2020

Autophagy-mediated metabolic effects of aspirin

scientific article published on 24 November 2020

Autophagy: a druggable process that is deregulated in aging and human disease

scientific article

Autophagy: evolutionary and pathophysiological insights

scientific article published in September 2009

Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia

scientific article

B709 Mitochondrial Control of Cell Death

scientific article published on 05 October 2001

BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy

scientific article published in January 2015

BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer

scientific article published on 01 June 2022

BH3 mimetics activate multiple pro-autophagic pathways

scientific article published on 4 April 2011

BH3 mimetics reveal the network properties of autophagy-regulatory signaling cascades

scientific article published on August 1, 2011

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

scientific article published on 04 July 2007

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.

scientific article

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells

scientific article published on 11 October 2019

Bacterial infection and non-Hodgkin's lymphoma

scientific article published on 15 May 2020

Bacterial invasion: linking autophagy and innate immunity

scientific article published on 01 February 2010

Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE1α signaling

scientific article published on 19 February 2018

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

scientific article

Bcl-2 and Bax modulate adenine nucleotide translocase activity.

scientific article published in January 2003

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

scientific article

Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.

scientific article published in January 1997

Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma

scientific article published in November 2004

Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells

scientific article published on 01 December 2000

Bcl-2 family members: dual regulators of apoptosis and autophagy

scientific article published on 12 May 2008

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

scientific article

Beclin 1: a BH3-only protein that fails to induce apoptosis

scientific article published on 27 April 2009

Bid acts on the permeability transition pore complex to induce apoptosis

scientific article

Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection

scientific article

Biological Functions of Autophagy Genes: A Disease Perspective

scientific article published on 01 January 2019

Biomarkers of immunogenic stress in metastases from melanoma patients: Correlations with the immune infiltrate

scientific article

CANCER. A p53-regulated immune checkpoint relevant to cancer

scientific article published on 01 July 2015

CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy

scientific article published on 3 December 2013

CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance

scientific article published on 10 November 2014

CD4+ T Cells at the Center of Inflammaging

scientific article published on 25 April 2020

CD4-targeted immune intervention: a strategy for the therapy of AIDS and autoimmune disease

scientific article published on April 1, 1991

CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways

scientific article published on 01 September 1996

CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer

scientific article published on 14 August 2020

CHCHD4 links AIF to the biogenesis of respiratory chain complex I.

scientific article published on 29 July 2015

COVID-19: a challenge for oncology services

scientific article published on 05 May 2020

Calcium signaling and cell cycle: Progression or death.

scientific article published on 25 July 2017

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

scientific article published on July 2016

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

scientific article published on 01 March 2019

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

scientific article

Caloric restriction mimetics for the treatment of cardiovascular diseases

scientific article published on 24 October 2020

Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

scientific article published in January 2014

Caloric restriction mimetics: towards a molecular definition

scientific article published on 12 September 2014

Caloric restriction promotes the stemness and antitumor activity of T lymphocytes

scientific article published on 16 May 2019

Calreticulin Expression in Human Non-Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis

scientific article published on 3 February 2016

Calreticulin and cancer

scientific article published on 30 July 2020

Calreticulin and type I interferon: An unsuspected connection

scientific article

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

scientific article

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients

scientific article published on 20 November 2019

Calreticulin exposure dictates the immunogenicity of cancer cell death

scientific article

Calreticulin exposure is required for the immunogenicity of γ-irradiation and UVC light-induced apoptosis

article by M Obeid et al published 27 July 2007 in Cell Death & Differentiation

Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

scientific article

Calreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer

scientific article published on 09 June 2016

Can autophagy promote longevity?

scientific article

Can the exome and the immunome converge on the design of efficient cancer vaccines?

scientific article

Cancer Cells Thrive on Stress

scientific article published on 05 April 2019

Cancer and the gut microbiota: an unexpected link

scientific article published on January 2015

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

scientific article

Cancer despite immunosurveillance: immunoselection and immunosubversion

scientific article

Cancer immunotherapy in 2017: The breakthrough of the microbiota

scientific article

Cancer is not just a disease of a tissue: It is a host disease

scientific article published on 16 April 2008

Cancer therapy: Altering mitochondrial properties

scientific article published on 01 February 2014

Cancer-Induced Endoplasmic Reticulum Stress in T Cells Subverts Immunosurveillance

scientific article published on 01 December 2018

Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells

scientific article published on 16 March 2012

Cancer: Antibodies regulate antitumour immunity

scientific article

Cancer: defeating the immortal

scientific article published on 13 August 2007

Carbotoxicity-Noxious Effects of Carbohydrates

scientific article published on 01 October 2018

Cardiac glycosides exert anticancer effects by inducing immunogenic cell death

scientific article

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Cardioprotective effects of autophagy induction in sepsis

scientific article published on 01 November 2018

Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.

scientific article published on 10 March 2017

Caspase activation is not death

article by Jean-Luc Perfettini & Guido Kroemer published April 2003 in Nature Immunology

Caspase independence of radio-induced cell death

scientific article published on 24 July 2006

Caspase-3 and prostaglandins signal for tumor regrowth in cancer therapy

scientific article published on 03 October 2011

Caspase-dependent and caspase-independent cell death pathways in yeast

scientific article published on 27 February 2009

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

scientific article

Caspase-independent cell death

scientific article

Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult.

scientific article published in August 2000

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

scientific article

Caspases disrupt mitochondrial membrane barrier function.

scientific article published in May 1998

Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF.

scientific article published on 29 September 2006

Cell Death and Disease: a new journal for a central area of pathophysiology

scientific article published on January 1, 2010

Cell Stress - a new journal for cellular pathophysiology

scientific article published on 01 October 2017

Cell biology. Metabolic control of cell death

scientific article

Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells

scientific article published in May 2006

Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy

scientific article published on 2 July 2007

Cell death assays for drug discovery

scientific article published on March 2011

Cell death by mitotic catastrophe: a molecular definition

scientific article

Cell death by necrosis: towards a molecular definition

scientific article published on December 2006

Cell death mechanisms in HIV-associated dementia: the involvement of syncytia

scientific article published in August 2005

Cell death modalities: classification and pathophysiological implications

scientific article published on 13 April 2007

Cell death pathways in retroviral infection.

scientific article published in August 2005

Cell death signaling and anticancer therapy

scientific article

Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).

scientific article published in March 2002

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

scientific article published in March 2001

Cell-Surface-Expressed HIV-1 Envelope Induces the Death of CD4 T Cells during GP41-Mediated Hemifusion-like Events

scientific article published on 01 January 2003

Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor

scientific article published on 05 September 2019

Cell-death-associated molecular patterns as determinants of cancer immunogenicity

scientific article published on 20 March 2013

Cellular degradation systems in ferroptosis

publication published on 18 January 2021

Ceramide triggers metacaspase-independent mitochondrial cell death in yeast

article by Didac Carmona-Gutierrez et al published 15 November 2011 in Cell Cycle

Change in HER2 (ERBB2) gene status after taxane-based chemotherapy for breast cancer: polyploidization can lead to diagnostic pitfalls with potential impact for clinical management.

scientific article

Chaperone-mediated autophagy degrades mutant p53.

scientific article published on August 2013

Chaperone-mediated autophagy degrades mutant p53.

scientific article published in September 2013

Chapter Eighteen Methods to Dissect Mitochondrial Membrane Permeabilization in the Course of Apoptosis

scientific article published on 01 January 2008

Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis

scientific article

Characterization of novel MPS1 inhibitors with preclinical anticancer activity

scientific article

Characterization of staphylococci in microtiter-plates (author's transl)

scientific article published on January 1, 1977

Charming to death: caspase-dependent or -independent?

scientific article published on 01 March 2003

Chemical activation of SAT1 corrects diet-induced metabolic syndrome

scientific article published on 06 May 2020

Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma.

scientific article

Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy

scientific article published on 10 January 2014

Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant.

scientific article published in December 2003

Chemosensitization by erythropoietin through inhibition of the NF-kappaB rescue pathway

scientific article

Chemosensitization by knockdown of adenine nucleotide translocase-2.

scientific article published on September 2006

Chemosensitization strategies for the treatment of lung cancer

scientific article

Chemotherapy and radiotherapy: cryptic anticancer vaccines

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scientific article

Peroxisome: the new player in ferroptosis

scientific article published on 24 November 2020

Personalization of therapies in rare diseases: a translational approach for the treatment of cystic fibrosis

scientific article published on 13 February 2019

Personalized immunotherapy: a siren myth?

scientific article published on 01 September 2009

Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes

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Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity

scientific article published on 01 May 1994

Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells

scientific article published on 01 November 1995

Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells.

scientific article published on 4 August 2015

Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection.

scientific article published on 18 March 2009

Pharmacological inhibition of programmed lymphocyte death

scientific article published on May 1994

Pharmacological inhibitors of anaplastic lymphoma kinase (ALK) induce immunogenic cell death through on-target effects

scientific article published on 16 July 2021

Pharmacological manipulation of cell death: clinical applications in sight?

scientific article

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

scientific article

Pharmacological suppression of B7-H4 glycosylation restores antitumor immunity in immune-cold breast cancers

scientific article published on 16 September 2020

Phosphatidylethanolamine positively regulates autophagy and longevity

scientific article

Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers

scientific article published on May 2012

Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy

scientific article published on 08 June 2020

Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus

scientific article published on 28 May 2018

Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals

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Physical interaction of apoptosis-inducing factor with DNA and RNA.

scientific article published in March 2006

Physiology and pathology of an immunoendocrine feedback loop

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Plasma membrane potential in thymocyte apoptosis

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Platelet formation is the consequence of caspase activation within megakaryocytes

scientific article published in August 2002

Polyethylene Glycol-Modified IL-2 Abrogates Superantigen-Induced Anergy without Affecting Peripheral Clonal Deletionin Vivo

scientific article published on 01 March 1996

Positive impact of autophagy in human breast cancer cells on local immunosurveillance

scientific article published on 24 May 2016

Possible contribution of apoptosis-inducing factor (AIF) and reactive oxygen species (ROS) to UVB-induced caspase-independent cell death in the T cell line Jurkat

scientific article

Potassium leakage during the apoptotic degradation phase.

scientific article published on June 1998

Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate

scientific article published on 16 October 2018

Potential mechanisms of cancer prevention by nicotinamide

scientific article published on 07 May 2020

Pre-processed caspase-9 contained in mitochondria participates in apoptosis

scientific article published in January 2002

Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.

scientific article published on 21 October 2004

Predictive biomarkers for cancer therapy with PARP inhibitors.

scientific article published on 16 September 2013

Predictors of responses to immune checkpoint blockade in advanced melanoma

scientific article published on 19 September 2017

Preface

Preface

Preface: oncometabolism: a new field of research with profound therapeutic implications

scientific article published on 01 January 2014

Preface: oncometabolism: a new field of research with profound therapeutic implications

Preferential killing of p53-deficient cancer cells by reversine.

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Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.

scientific article published on 27 April 2009

Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death

scientific article published on 24 February 2012

Prerequisites for the antitumor vaccine-like effect of chemotherapy and radiotherapy

scientific article published on September 2011

Prevention of breast cancer by RANKL/RANK blockade

scientific article published on 21 June 2016

Prime time for immune-checkpoint targeted therapy at ASCO 2015

scientific article

Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope

scientific article published on 15 February 2009

Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins

scientific article

Pro-necrotic molecules impact local immunosurveillance in human breast cancer

scientific article

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

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Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer

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Prognostic and predictive impact of intra- and peritumoral immune infiltrates

scientific article published on 16 August 2011

Prognostic impact of anticancer immune responses: an introduction

scientific article published on May 28, 2011

Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer

scientific article published on 13 May 2016

Prognostic value of LIPC in non-small cell lung carcinoma

scientific article

Programmed mitophagy is essential for the glycolytic switch during cell differentiation

scientific article published on 2 May 2017

Programmed necrosis from molecules to health and disease

scientific article published on January 2011

Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis

scientific article published on 06 July 2021

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

scientific article published on 17 August 2018

Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria

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Proteasome activation as a critical event of thymocyte apoptosis

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Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis

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Protein kinase C isoenzymes display differential affinity for phorbol esters. Analysis of phorbol ester receptors in B cell differentiation

scientific article published on October 15, 1992

Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients

scientific article

Pseudodiabetes-not a contraindication for metabolic interventions

scientific article published on 10 October 2019

Publisher Correction: Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

scientific article published on 17 September 2020

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

scientific article published on 01 July 2019

Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

scientific article published on 01 September 2018

Purification and liposomal reconstitution of permeability transition pore complex

scientific article published on 01 January 2000

Purification of mitochondria for apoptosis assays

scientific article published on 01 January 2000

Pyroptosis - a cell death modality of its kind?

scientific article published on March 2010

Quantification of cell cycle-arresting proteins

scientific article published in January 2013

Quantification of cellular viability by automated microscopy and flow cytometry

scientific article published on April 2015

Quantification of eIF2alpha phosphorylation during immunogenic cell death

scientific article published on 27 April 2019

Quantitation of calreticulin exposure associated with immunogenic cell death

scientific article published on 03 June 2019

Quantitation of mitochondrial alterations associated with apoptosis

scientific article

Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria

scientific article published on 01 January 2000

Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry

scientific article published on 02 August 2019

Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia

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Quinacrine-mediated detection of intracellular ATP

scientific article published on 17 June 2019

RIP kinases initiate programmed necrosis

scientific article published on 13 August 2009

RIP3 attenuates the pancreatic damage induced by deletion of ATG7.

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Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.

scientific article published on 16 April 2009

Radiosensitization by a novel Bcl-2 and Bcl-XL inhibitor S44563 in small-cell lung cancer

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Re-examining the role of cytochrome c in cell death

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Redaporfin induces immunogenic cell death by selective destruction of the endoplasmic reticulum and the Golgi apparatus

scientific article published on 27 July 2018

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function

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Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

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Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin.

scientific article published on 23 November 2007

Redundant cell death mechanisms as relics and backups

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Regulated cell death and adaptive stress responses

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Regulated necrosis.

scientific article published on 20 August 2014

Regulation of autophagy by cytoplasmic p53

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Regulation of autophagy by cytosolic acetyl-coenzyme A.

scientific article published on 20 February 2014

Regulation of autophagy by stress-responsive transcription factors

scientific article published on 30 May 2013

Regulation of autophagy by the inositol trisphosphate receptor

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Regulation of cytoplasmic stress granules by apoptosis-inducing factor

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Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death

scientific article published on 27 October 2020

Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo

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Reply to Gostner and Fuchs

scientific article published on 01 January 2019

Reply to ‘F508del-CFTR is not corrected by thymosin α1’

scientific article published on 01 July 2018

Reply: Immunosuppressive cell death in cancer

scientific article published on 8 May 2017

Repurposing CD8+ T cell immunity against SARS-CoV-2 for cancer immunotherapy: a positive aspect of the COVID-19 pandemic?

scientific article published on 16 July 2020

Repurposing therapies for the personalised treatment of cystic fibrosis

scholarly article by Antonella Tosco et al published 3 June 2018 in Expert opinion on orphan drugs

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors

scientific article published on June 2016

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

scientific article published in January 2014

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

scientific article published on 13 December 2010

Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

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Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

scientific article

Retrospective electron microscopy: Preservation of fine structure by freezing and aldehyde fixation

scientific article published on 27 October 2016

Reverse Warburg: Straight to cancer

scientific article published on March 15, 2012

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

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Role of the mitochondrial permeability transition pore in apoptosis

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STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells

scientific article published on 24 July 2015

STAT3 inhibition for cancer therapy: Cell-autonomous effects only?

scientific article published on 8 January 2016

SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends

scientific article published on 08 June 2020

Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set

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Secondary Necrosis: Accidental No More

scientific article published on 03 January 2017

Secreted calreticulin mutants subvert anticancer immunosurveillance

scientific article published on 28 December 2019

Seeking Cellular Fitness and Immune Evasion: Autophagy in Pancreatic Carcinoma

scientific article published on 25 May 2020

Selective killing of p53-deficient cancer cells by SP600125.

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Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis

scientific article published on December 2006

Self-consumption: the interplay of autophagy and apoptosis

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

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Senescence, apoptosis or autophagy? When a damaged cell must decide its path--a mini-review

scientific article published on 02 May 2008

Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

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Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

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Shigella targets the mitochondrial checkpoint of programmed necrosis

scientific article published on February 2009

Side-by-side comparison of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death

scientific article published on 08 July 2019

Signal transduction pathways involved in B-cell induction

scientific article

Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides

scientific article published in May 2000

SnapShot: Macroautophagy

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Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

scientific article

Spermidine delays aging in humans

Spermidine in health and disease.

scientific article

Spermidine induces autophagy by inhibiting the acetyltransferase EP300.

scientific article

Spermidine promotes mating and fertilization efficiency in model organisms

scientific article published on 15 January 2012

Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways

scientific article

Spermidine protects against α-synuclein neurotoxicity.

scientific article

Spermidine reduces cancer-related mortality in humans

scholarly article by Federico Pietrocola published in October 2018

Spermidine: a novel autophagy inducer and longevity elixir

scientific article published on January 2010

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

scholarly article by Frank Madeo published in October 2018

Spontaneous DNA damage propels tumorigenicity.

scientific article

Spontaneous autoimmune thyroiditis: new therapeutic strategies

scientific article published on January 1990

Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

scientific article published on 11 March 2019

Stimulation of autophagy by the p53 target gene Sestrin2.

scientific article published on 20 May 2009

Strategies for the etiological therapy of cystic fibrosis

scientific article

Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity

scientific article published on 09 September 2019

Structure and expression of a chicken MHC class I gene

scientific article published on January 1990

Structure–function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA

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Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins

scientific article published on April 30, 1998

Subversion of anticancer immunosurveillance by radiotherapy.

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Subversion of the chemotherapy-induced anticancer immune response by the ecto-ATPase CD39.

scientific article published on May 2012

Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome

scientific article published on 27 April 2009

Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion

scientific article published on 06 September 2019

Surface-exposed and soluble calreticulin: conflicting biomarkers for cancer prognosis

scientific article published on 20 July 2020

Surface-exposed calreticulin in the interaction between dying cells and phagocytes

scientific article published on October 2010

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

scientific article published on 03 September 2019

Syncytial apoptosis signaling network induced by the HIV-1 envelope glycoprotein complex: an overview.

scientific article

Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer

scientific article published on 21 February 2013

Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines

scientific article published on 14 September 2009

Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress

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Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy

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Systems biology of cisplatin resistance: past, present and future

scientific article

T cell hyperproliferation in autoimmunity prone obese strain (OS) chickens is independent of abnormal mitogen binding in vitro and can be demonstrated in vivo

scientific article published on 01 January 1988

T-Lymphocyte Subsets in the Embryonic Spleen Undergoing a Graft-Versus-Host Reaction

scientific article published on January 1, 1991

T-cell bispecific antibodies in node-positive breast cancer: novel therapeutic avenue for MHC class I loss variants

scientific article published on 01 June 2019

TFAM is a novel mediator of immunogenic cancer cell death.

scientific article

TG2 regulates the heat-shock response by the post-translational modification of HSF1

scientific article published on 11 May 2018

TMEM173 Drives Lethal Coagulation in Sepsis

scientific article published on 05 March 2020

TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer

scientific article published on 11 October 2017

TP53 and 53BP1 Reunited

scientific article published on 17 November 2016

TP53 and MTOR crosstalk to regulate cellular senescence

scientific article published on September 2010

Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere

scientific article published on 27 February 2018

Tantalizing Thanatos: unexpected links in death pathways

scientific article published on 01 July 2002

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

scientific article published in November 2007

Targeting GATA transcription factors - a novel strategy for anti-aging interventions?

scientific article published on 06 May 2019

Targeting HSP70 for cancer therapy

scientific article published in October 2009

Targeting NF-kappaB in hematologic malignancies

scientific article

Targeting PD-1/PD-L1 interactions for cancer immunotherapy

scientific article published on November 1, 2012

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

scientific article

Targeting dendritic cell metabolism in cancer

scientific article published on 01 August 2010

Targeting foxp1 for reinstating anticancer immunosurveillance

scientific article published on 01 September 2014

Targeting mitochondria for cancer therapy

scientific article

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles

scientific article published on 01 January 2019

Targeting mitochondrial apoptosis by betulinic acid in human cancers

scientific article published on 09 June 2009

Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells

scientific article published on 26 January 2012

Targeting p53 to mitochondria for cancer therapy

scientific article published on July 2008

Targeting post-mitochondrial effectors of apoptosis for neuroprotection

scientific article published on 24 September 2008

Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

scientific article published on January 21, 2013

Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy

scientific article published on 10 April 2016

Tetraploid cancer cell precursors

scientific article published on 23 June 2010

Tetraploid cancer cell precursors in ovarian carcinoma

scientific article published on 16 August 2012

The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway

scientific article (publication date: November 2002)

The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models

scientific article published on 16 November 2012

The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs

scientific article

The European Academy of Tumor Immunology: Bridging fields, continents and generations

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The European Cell Death Group

scientific article published on 01 April 2001

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

scientific article

The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

scientific article published on 04 April 2022

The IKK complex contributes to the induction of autophagy

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The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer

scientific article published on 20 July 2019

The Multifaceted Roles of MicroRNAs in Cystic Fibrosis

scientific article published on 17 December 2020

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins

scientific article published on April 20, 1998

The Role of Micro-RNAs and Circulating Tumor Markers as Predictors of Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer

scientific article published on 24 September 2020

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

scientific article published on 04 May 2016

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

scientific article published on September 2016

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

scientific article published in August 2017

The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer

scientific article

The abundance of the long intergenic non-coding RNA 01087 differentiates between luminal and triple-negative breast cancers and predicts patient outcome

scientific article published on 14 October 2020

The adenine nucleotide translocator in apoptosis

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The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal

scientific article published in July 2001

The ambiguous role of FPR1 in immunity and inflammation

scientific article published on 30 April 2020

The anticancer immune response: indispensable for therapeutic success?

scientific article published on June 2008

The anticancer peptide RT53 induces immunogenic cell death

scientific article published in PLoS ONE

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

scientific article published on September 25, 1997

The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

scientific article published on 28 June 2005

The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe

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The autophagic network and cancer

scientific article published on 23 February 2018

The beauty of death

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The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis

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The biochemistry of programmed cell death

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The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe

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The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

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The central executioners of apoptosis: caspases or mitochondria?

scientific article published on 01 July 1998

The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes

scientific article published on January 1, 1998

The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family

scientific article published in September 2003

The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

scientific article

The complement system is also important in immunogenic cell death

The crystal structure of the mouse apoptosis-inducing factor AIF

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The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells

scientific article published in August 2009

The dendritic cell-tumor cross-talk in cancer

scientific article published on 21 October 2010

The dilemma of anticancer therapy: tumor-specific versus immune effects

scientific article published in December 2008

The effects of p53 on whole organism longevity are mediated by autophagy

scientific article published on 04 October 2008

The elusive "hunger protein": an appetite-stimulatory factor that is overabundant in human obesity

scientific article published on 15 October 2019

The end of autophagic cell death?

scientific article published on 01 January 2012

The fabulous legacy of a Nobel Prize Laureate: Ralph M. Steinman, 1943-2011.

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The fail-safe paradigm of immunological self-tolerance

scientific article published on November 16, 1991

The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species

scientific article published on 19 February 2019

The gliadin-CFTR connection: new perspectives for the treatment of celiac disease

The grand challenges to cellular and molecular oncology

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The gut microbiota influences anticancer immunosurveillance and general health

scientific article published on 10 April 2018

The hallmarks of aging

scientific article

The hallmarks of successful anticancer immunotherapy

scientific article published on 01 September 2018

The holy grail of cystic fibrosis research: pharmacological repair of the F508del-CFTR mutation

scientific article published on May 2015

The immune contexture in cancer prognosis and treatment

scientific article published on 25 July 2017

The immune response against dying tumor cells: avoid disaster, achieve cure

scientific article published in January 2008

The immune system: taming and unleashing cancer

scientific article published on 01 December 2006

The immunogenicity of tumor cell death

scientific article published on January 2009

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

scientific article published on 27 March 2009

The inositol trisphosphate receptor in the control of autophagy

scientific article published on 27 July 2007

The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

scientific article published on December 2007

The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1

scholarly article by Lisa Derosa et al published 2018 in OncoImmunology

The intimate relationship between gut microbiota and cancer immunotherapy

scholarly article by Arielle Elkrief et al published 19 October 2018 in Gut microbes

The life span-prolonging effect of sirtuin-1 is mediated by autophagy

scientific article published on 02 January 2010

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas

scientific article

The metabolomic signature of extreme longevity: naked mole rats versus mice

scientific article published on 01 July 2019

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies

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The mitochondrial death/life regulator in apoptosis and necrosis

scientific article published on January 1, 1998

The mitochondrial pathway in yeast apoptosis

scientific article published on May 2007

The mitochondrial permeability transition pore complex as a pharmacological target. An introduction

scientific article

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.

scientific article published on 13 July 2009

The mitochondrion as an integrator/coordinator of cell death pathways

scientific article published on 01 June 1998

The mitochondrion in apoptosis: how Pandora's box opens

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The mitochondrion in cell death control: certainties and incognita

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The mitochondriotoxic domain of Vpr determines HIV-1 virulence

scientific article published on May 1, 2003

The molecular archaeology of a mitochondrial death effector: AIF in Drosophila

scientific article

The molecular machinery of regulated cell death

scientific article published on 04 April 2019

The multifaceted granulysin

scientific article published on 01 November 2010

The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?

scientific article published on 01 October 2019

The neuroprotective steroid progesterone promotes mitochondrial uncoupling, reduces cytosolic calcium and augments stress resistance in yeast cells

scientific article

The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.

scientific article

The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis

scientific article published on January 1989

The oncolytic compound LTX-401 targets the Golgi apparatus

scientific article published on 10 November 2017

The oncolytic compound LTX-401 targets the Golgi apparatus

scientific article published on 2 September 2016

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization

scientific article

The oncolytic peptide LTX-315 overcomes resistance of cancers to immunotherapy with CTLA4 checkpoint blockade

scientific article published on 15 April 2016

The oncolytic peptide LTX-315 triggers immunogenic cell death

scientific article published on 10 March 2016

The oncolytic peptide LTX-315 triggers necrotic cell death

scientific article published on November 2015

The pathophysiology of mitochondrial cell death

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The pharmacology of T cell apoptosis

scientific article published on January 1995

The place of mitochondria in apoptosis.

scientific article published on 26 January 2001

The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer

scientific article published on 16 March 2016

The propeptide of yeast cathepsin D inhibits programmed necrosis.

scientific article

The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma

scientific article published on 24 January 2014

The proto-oncogene Bcl-2 and its role in regulating apoptosis

scientific article published on June 1997

The ratio of CD8+/FOXP3 T lymphocytes infiltrating breast tissues predicts the relapse of ductal carcinoma in situ

scientific article published on 18 August 2016

The role of interleukin 2 in autoimmunity

scientific article

The role of interleukin 2 in the development of autoimmune thyroiditis

scientific article published on January 1, 1992

The scent of death: a metabolic goodbye signal emitted by dying cells

scientific article published on 06 April 2020

The secret ally: immunostimulation by anticancer drugs

scientific article published on 03 February 2012

The spectrum of T cell metabolism in health and disease

scientific article published on 25 September 2017

The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

scientific article published on 01 February 1998

The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope.

scientific article published on 21 November 2008

The tumor suppressor protein p53 and the ferroptosis network.

scientific article

The ultimate goal of curative anti-cancer therapies: inducing an adaptive anti-tumor immune response

scientific article published on December 2011

Therapeutic modulation of autophagy: which disease comes first?

scientific article published on 06 February 2019

Therapy-induced microenvironmental changes in cancer

scientific article published on 2 March 2016

Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells

scientific article published on February 2007

Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

scientific article

To die or not to die: that is the autophagic question

scientific article published on March 2008

Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

scientific article published on 11 October 2018

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

scientific article (publication date: September 2007)

Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR.

scientific article published on 25 June 2013

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids.

scientific article

Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations

scientific article

Transient Autophagy Inhibition Precipitates Oncogenesis: A Red Flag For Pharmacological Autophagy Inhibitors?

scientific article published on 27 February 2020

Transmission of innate immune signaling by packaging of cGAMP in viral particles

scientific article

Trial Watch

scientific article

Trial Watch-Immunostimulation with cytokines in cancer therapy

scientific article

Trial Watch-Oncolytic viruses and cancer therapy

scientific article

Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy

scientific article published on 10 March 2016

Trial Watch: Adoptive cell transfer for anticancer immunotherapy

scientific article published on May 2013

Trial Watch: Adoptive cell transfer for anticancer immunotherapy

scientific article published on May 2014

Trial Watch: Adoptive cell transfer for oncological indications

scientific article

Trial Watch: Adoptive cell transfer immunotherapy

scientific article

Trial Watch: Adoptively transferred cells for anticancer immunotherapy

scientific article published on 11 August 2017

Trial Watch: Anticancer radioimmunotherapy

scientific article published on 3 July 2013

Trial Watch: Chemotherapy with immunogenic cell death inducers.

scientific article published in January 2014

Trial Watch: DNA vaccines for cancer therapy

scientific article published on January 2014

Trial Watch: Experimental Toll-like receptor agonists for cancer therapy

scientific article

Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy

scientific article

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications

scientific article

Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy

scientific article

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy

scholarly article by Elena García-Martínez et al published 2018 in OncoImmunology

Trial Watch: Immunostimulatory cytokines

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Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications

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