List of works - Michael Sheetz

Local force and geometry sensing regulate cell functions

scientific article (publication date: April 2006)

Stretching single talin rod molecules activates vinculin binding

scientific article

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

scientific article (publication date: December 2006)

Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

scientific article published on November 11, 2003

Lamellipodial actin mechanically links myosin activity with adhesion-site formation

scientific article

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

scientific article

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

scientific journal article

Single pilus motor forces exceed 100 pN.

scientific article

Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction

scientific article

Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

scientific article

Activation of a signaling cascade by cytoskeleton stretch

scientific article

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

scientific article

Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading.

scientific article

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

scientific article

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

scientific article published on March 20, 2013

Cytoskeletal coherence requires myosin-IIA contractility

scientific article

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

scientific article

Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading

scientific article

Cells test substrate rigidity by local contractions on submicrometer pillars.

scientific article

Force generated by actomyosin contraction builds bridges between adhesive contacts

scientific article

Transformation proteins and DNA uptake localize to the cell poles in Bacillus subtilis

scientific article published on July 2005

Cooperative retraction of bundled type IV pili enables nanonewton force generation

scientific article (publication date: 15 April 2008)

Immediate-early signaling induced by E-cadherin engagement and adhesion

scientific article

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

scientific journal article

Force-dependent polymorphism in type IV pili reveals hidden epitopes.

scientific article

A force-dependent switch reverses type IV pilus retraction

scholarly article

Plasma membrane area increases with spread area by exocytosis of a GPI-anchored protein compartment.

scientific article

Cyclic stretching of soft substrates induces spreading and growth

scientific article

DNA transport into Bacillus subtilis requires proton motive force to generate large molecular forces

scientific article

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices

scientific article

Direct evidence for coherent low velocity axonal transport of mitochondria

scientific article

A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex.

scientific article

Analysis of the local organization and dynamics of cellular actin networks

scientific article

T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse

scientific article

An in vivo covalent TMP-tag based on proximity-induced reactivity

scientific article published on July 2009

Second-Generation Covalent TMP-Tag for Live Cell Imaging

scientific article published on August 9, 2012

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling

scientific article

Methotrexate conjugates: a molecular in vivo protein tag.

scientific article published on March 2004

Netrin-1 attracts axons through FAK-dependent mechanotransduction

scientific article

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

scientific article

Mechanisms controlling cell size and shape during isotropic cell spreading

scientific article

Mechanosensing Controlled Directly by Tyrosine Kinases.

scientific article

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

scientific article

Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading

scientific article

N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.

scientific article

Structural effects of PrP polymorphisms on intra- and interspecies prion transmission.

scientific article

Early events in cell spreading as a model for quantitative analysis of biomechanical events

scientific article

Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.

scientific article

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

scientific article published on December 15, 2013

Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.

scientific article

List of works by Michael Sheetz

Local force and geometry sensing regulate cell functions

Stretching single talin rod molecules activates vinculin binding

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

Lamellipodial actin mechanically links myosin activity with adhesion-site formation

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

Single pilus motor forces exceed 100 pN.

Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction

Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

Activation of a signaling cascade by cytoskeleton stretch

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading.

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

Cytoskeletal coherence requires myosin-IIA contractility

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading

Cells test substrate rigidity by local contractions on submicrometer pillars.

Force generated by actomyosin contraction builds bridges between adhesive contacts

Transformation proteins and DNA uptake localize to the cell poles in Bacillus subtilis

Cooperative retraction of bundled type IV pili enables nanonewton force generation

Immediate-early signaling induced by E-cadherin engagement and adhesion

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

Force-dependent polymorphism in type IV pili reveals hidden epitopes.

A force-dependent switch reverses type IV pilus retraction

Plasma membrane area increases with spread area by exocytosis of a GPI-anchored protein compartment.

Cyclic stretching of soft substrates induces spreading and growth

DNA transport into Bacillus subtilis requires proton motive force to generate large molecular forces

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices

Direct evidence for coherent low velocity axonal transport of mitochondria

A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex.

Analysis of the local organization and dynamics of cellular actin networks

T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse

An in vivo covalent TMP-tag based on proximity-induced reactivity

Second-Generation Covalent TMP-Tag for Live Cell Imaging

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling

Methotrexate conjugates: a molecular in vivo protein tag.

Netrin-1 attracts axons through FAK-dependent mechanotransduction

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

Mechanisms controlling cell size and shape during isotropic cell spreading

Mechanosensing Controlled Directly by Tyrosine Kinases.

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading

N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.

Structural effects of PrP polymorphisms on intra- and interspecies prion transmission.

Early events in cell spreading as a model for quantitative analysis of biomechanical events

Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.