Search filters

List of works by Ernest Giralt i Lledó

'À la carte' peptide shuttles: tools to increase their passage across the blood-brain barrier

scientific article published on 24 March 2014

13C-NMR spectra of fluorinated molecules using 19F-13C polarization transfer

14-helical folding in a cyclobutane-containing beta-tetrapeptide

scientific article published in July 2004

15N relaxation NMR studies of prolyl oligopeptidase, an 80 kDa enzyme, reveal a pre-existing equilibrium between different conformational states

scientific article published on 08 November 2011

1H(N), 15N, 13CO, 13Calpha, 13Cbeta assignment and secondary structure of a 20 kDa alpha-L-fucosidase from pea using TROSY

scientific article published on 01 March 2002

3D structure of kaliotoxin: is residue 34 a key for channel selectivity?

article

A MALDI-TOF-based Method for Studying the Transport of BBB Shuttles-Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models

A New Class of Foldamers Based oncis-γ-Amino-l-proline [J. Am. Chem. Soc.2004,126, 6048−6057]

scientific article published in 2005

A betamimetic drug and human fetal lung maturation ⬇️

scientific article published on August 1, 1979

A comparative study of cyclization strategies applied to the synthesis of head-to-tail cyclic analogs of a viral epitope

scientific article published on 01 January 1999

A cost-effective labeling strategy for the NMR study of large proteins: selective 15N-labeling of the tryptophan side chains of prolyl oligopeptidase

scientific article published in November 2009

A cyclic disulfide peptide reproduces in solution the main structural features of a native antigenic site of foot-and-mouth disease virus ⬇️

scientific article published on June 1, 1997

A fast and robust 19F NMR-based method for finding new HIV-1 protease inhibitors

scientific article published on 06 March 2006

A new approach to Hmb-backbone protection of peptides: Synthesis and reactivity of Nα-Fmoc-Nα-(Hmb)amino acids

A new approach to the solid-phase peptide synthesis of peptide alkyl-amides and esters

A new class of foldamers based on cis-gamma-amino-L-proline

scientific article

A new flourene-derived anchor for solid-phase synthesis of protected peptides

A new ionizable chromophore of 1,4-bis(alkylamino)benzo[g]phthalazine which interacts with DNA by intercalation

scientific article published on 01 January 1991

A new method for the preparation of unprotected peptides on biocompatible resins with application in combinatorial chemistry

scientific article

A new quinoxaline-containing peptide induces apoptosis in cancer cells by autophagy modulation

scientific article published on 20 May 2015

A new side opening on prolyl oligopeptidase revealed by electron microscopy.

scientific article published on 25 September 2009

A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles

scientific article published in January 2009

A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones.

scientific article published in October 2011

A synthetic strategy for simultaneous purification-conjugation of antigenic peptides

scientific article published on 01 September 1989

A tetraguanidinium ligand binds to the surface of the tetramerization domain of protein P53.

scientific article published in January 2004

AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES

article by Fernando Albericio et al published January 2001 in Synthetic Communications

AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.

scientific article published in April 2005

Abbreviated nomenclature for cyclic and branched homo- and hetero-detic peptides.

scientific article published in June 2005

Absence of a stable secondary structure is not a limitation for photoswitchable inhibitors of β-arrestin/β-Adaptin 2 protein-protein interaction

scientific article published on January 2015

Acid-base properties of 4-nitro-l-histidine and related compounds

Active carbonate resins for solid-phase synthesis through the anchoring of a hydroxyl function. Synthesis of cyclic and alcohol peptides

Active carbonate resins: Application to the solid-phase synthesis of alcohol, carbamate and cyclic peptides

Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics.

scientific article

Activity-based probes for monitoring postproline protease activity

scientific article

Amphipathic peptides and drug delivery

scientific article

An Easy Entry to a New High-Symmetry, Large Molecular Framework for Molecular Recognition Studies and de Novo Protein Design. Solvent Modulation of the Spontaneous Formation of a Cyclic Monomer, Dimer, or Trimer from a Bis-cysteine Peptide

article by Miriam Royo et al published July 1998 in Journal of the American Chemical Society

An HPLC-ESMS study on the solid-phase assembly ofC-terminal proline peptides

scientific article published on 01 March 1999

An intramolecular O-N migration reaction on gold surfaces: toward the preparation of well-defined amyloid surfaces.

scientific article published in October 2009

An optimized method for (15)N R(1) relaxation rate measurements in non-deuterated proteins.

scientific article

Analysis of conformational equilibria in aplidine using selective excitation 2D NMR spectroscopy and molecular mechanics/dynamics calculations

scientific article

Analysis of the conformational preferences of (4R,5R)-4,5-bis(alkylcarbamoyl)-1,3-dioxolanes

Analyzing slowly exchanging protein conformations by ion mobility mass spectrometry: study of the dynamic equilibrium of prolyl oligopeptidase.

scientific article published on July 2016

Antibacterial evaluation of a collection of norfloxacin and ciprofloxacin derivatives against multiresistant bacteria.

scientific article published on 14 June 2006

Antigenicity modulation upon peptide cyclization: application to the GH loop of foot-and-mouth disease virus strain C1-Barcelona.

scientific article published in May 2001

Applications of 3-aminolactams: design, synthesis, and biological evaluation of a library of potential dimerisation inhibitors of HIV1-protease

scientific article

Applying the retro-enantio approach to obtain a peptide capable of overcoming the blood-brain barrier

scientific article published on 4 February 2015

Arylboronic acids and arylpinacolboronate esters in Suzuki coupling reactions involving indoles. Partner role swapping and heterocycle protection

scientific article published in October 2004

Aβ40 and Aβ42 Amyloid Fibrils Exhibit Distinct Molecular Recycling Properties

scientific article published on 12 April 2011

Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

scientific article

Benzimidazolium salts as small, nonpeptidic and BBB-permeable human prolyl oligopeptidase inhibitors

scientific article

Benzotriazol-1-yloxytris(dimethylamino) phosphonium Hexafluorophosphate

Bicyclic homodetic peptide libraries: comparison of synthetic strategies for their solid-phase synthesis

scientific article published in November 2003

Bike peptides: a ride through the membrane

scientific article

Blocking EGFR Activation with Anti-EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms

scientific article published on 21 September 2018

Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery

scientific article published on 18 May 2016

Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood-brain barrier transport.

scientific article published on 18 September 2018

Bromotryptophans and their incorporation in cyclic and bicyclic privileged peptides

scientific article published in 2018

Building Cell Selectivity into CPP-Mediated Strategies

scientific article

CD of proline-rich polypeptides: Application to the study of the repetitive domain of maize glutelin-2

scientific article published on 01 July 1993

CSA-131, a ceragenin active against colistin-resistant Acinetobacter baumannii and Pseudomonas aeruginosa clinical isolates

scientific article published on 7 September 2015

Cell cycle arrest and proapoptotic effects of the anticancer cyclodepsipeptide serratamolide (AT514) are independent of p53 status in breast cancer cells

scientific article published on 18 November 2005

Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity

scientific article published on 8 November 2017

Cell-penetrating cis-gamma-amino-l-proline-derived peptides.

scientific article published in July 2005

Cell-penetrating proline-rich peptidomimetics

scientific article

Chemical Composition and Inhibitory Effects of Hypericum brasiliense and H. connatum on Prolyl Oligopeptidase and Acetylcholinesterase Activities

scientific article published on 26 October 2015

Chemical Synthesis of 19F-labeled HIV-1 Protease using Fmoc-Chemistry and ChemMatrix Resin

article

Chemically synthesized peptide libraries as a new source of BBB shuttles. Use of mass spectrometry for peptide identification.

scientific article published on 20 July 2016

Combating virulence of Gram-negative bacilli by OmpA inhibition

scientific article published on 31 October 2017

Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.

scientific article published on 10 November 2015

Combined bottom-up and top-down mass spectrometry analyses of the pattern of post-translational modifications of Drosophila melanogaster linker histone H1.

scientific article published on 27 May 2012

Comparative study of supports for solid-phase coupling of protected-peptide segments

Computational study of the conformational preferences of the (R)-8-amino-pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane-8-carboxylic acid monopeptide

scientific article

Computer-aided design of fragment mixtures for NMR-based screening

scientific article

Conformational analysis of a potent SSTR3-selective somatostatin analogue by NMR in water solution

scientific article

Conformational analysis of the repeated sequence of glutelin-2, a maize storage protein

Conformational analysis of two cyclic disulfide peptides

scientific article published on 01 June 1991

Constrained derivatives of stylostatin 1. 1. Synthesis and biological evaluation as potential anticancer agents

scientific article published on December 2003

Convenient synthesis of a cyclic peptide disulfide: A type II β-turn structural model

article

Convergent Solid Phase Peptide Synthesis: An Efficient Approach to the Synthesis of Highly Repetitive Protein Domains

Convergent Synthesis of Repeating Peptides (Val-X-Leu-Pro-Pro-Pro)(8) Adopting a Polyproline II Conformation

scientific article published on October 1996

Convergent approaches for the synthesis of the antitumoral peptide, Kahalalide F. Study of orthogonal protecting groups

scientific article published in September 2006

Convergent solid-phase peptide synthesis

article

Convergent solid-phase peptide synthesis. X. Synthesis and purification of protected peptide fragments using the photolabile Nbb-resin

Convergent solid-phase peptide synthesis. XI. Synthesis and purification of protected peptide segments spanning the entire sequence of the uteroglobin monomer using the photolabile nbb-resin

Coupedu RoiBisection of Proteins. Spontaneous Tetramerization of Two Peptides That Span the Sequence of the Rabbit Uteroglobin Monomer

scientific article published on 01 December 2005

Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac

scientific article

Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes

scientific article published in May 2009

D-SAP: A New, Noncytotoxic, and Fully Protease Resistant Cell-Penetrating Peptide

scientific article published on 15 February 2008

DNA interaction and dual topoisomerase I and II inhibition properties of the anti-tumor drug prodigiosin

scientific article

De novo protein surface design: use of cation-pi interactions to enhance binding between an alpha-helical peptide and a cationic molecule in 50 % aqueous solution

scientific article

Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape

scientific article

Delivering wasp venom for cancer therapy

scientific article published on 12 March 2014

Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor

scientific article published on 15 July 2012

Design and synthesis of FAJANU: a de novo C(2) symmetric cyclopeptide family.

scientific article

Design of HR1 and HR2 synthetic peptide analogs: Characterization of their antiviral activities and their capacities to induce neutralizing antibodies

Design of enhanced agonists through the use of a new virtual screening method: application to peptides that bind class I major histocompatibility complex (MHC) molecules

scientific article published in August 2005

Design, synthesis and characterization of a new anionic cell-penetrating peptide: SAP(E).

scientific article published on March 2011

Design, synthesis, and complexing properties of (1Cys-1'Cys,4Cys-4'Cys)-dithiobis(Ac-L-1Cys-L-Pro-D-Val-L-4Cys-NH2). The first example of a new family of ion-binding peptides

scientific article published in 1993

Determination of interchain NOEs in symmetrical dimer peptides

scientific article published in 1991

Determination of the enantiomeric purity of synthetic peptides by gas chromatography—mass spectrometry ⬇️

scientific article published on 01 January 1991

Development and characterization of peptidic fusion inhibitors derived from HIV-1 gp41 with partial D-amino acid substitutions.

scientific article published in April 2009

Development of a Genetic Algorithm to Design and Identify Peptides that can Cross the Blood-Brain Barrier

article

Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine

scientific article

Differentiation restricted endocytosis of cell penetrating peptides in MDCK cells corresponds with activities of Rho-GTPases

scientific article published on 3 March 2007

Diketopiperazine formation in solid phase peptide synthesis using p-alkoxybenzyl ester resins and Fmoc-amino acids

article published in 1986

Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles

scientific article

Direct single-step surface plasmon resonance analysis of interactions between small peptides and immobilized monoclonal antibodies

scientific article published on 01 February 2000

Direct-reversible binding of small molecules to G protein βγ subunits

scientific article

Disruption of the HIV-1 protease dimer with interface peptides: structural studies using NMR spectroscopy combined with [2-(13)C]-Trp selective labeling

scientific article published in January 2007

Does the Solid-Phase Synthesis of a Tetrapeptide Represent a Challenge at the Onset of the XXI Century? The Case of Cyclo [(3R)-3-hydroxydecanoyl-l-seryl-(3R)-3-hydroxydecanoyl-l-seryl]

Drosophila dSAP18 is a nuclear protein that associates with chromosomes and the nuclear matrix, and interacts with pinin, a protein factor involved in RNA splicing.

scientific article

Dual system for the central nervous system targeting and blood-brain barrier transport of a selective prolyl oligopeptidase inhibitor

scientific article

ENPDA: an evolutionary structure-based de novo peptide design algorithm.

scientific article published in August 2005

Effects of L- and D-REKR amino acid-containing peptides on HIV and SIV envelope glycoprotein precursor maturation and HIV and SIV replication

scientific article published on September 2002

Efficient preparation of proline N-carboxyanhydride using polymer-supported bases

scientific article published on 01 November 2006

Electrochemical investigation of cellular uptake of quantum dots decorated with a proline-rich cell penetrating peptide

scientific article published on 19 January 2011

Electrostatic binding and hydrophobic collapse of peptide-nucleic acid aggregates quantified using force spectroscopy ⬇️

scientific article

Enthalpy- versus Entropy-Driven Molecular Recognition in the Era of Biologics

scientific article published on 02 October 2019

Evolutionary combinatorial chemistry, a novel tool for SAR studies on peptide transport across the blood-brain barrier. Part 2. Design, synthesis and evaluation of a first generation of peptides

scientific article published in December 2005

Evolutionary computation and multimodal search: a good combination to tackle molecular diversity in the field of peptide design

scientific article published on 13 December 2006

Expanding the MiniAp-4 BBB-shuttle family: Evaluation of proline cis-trans ratio as tool to fine-tune transport

scientific article published on 01 May 2019

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

scientific article

Exploration of the one-bead one-compound methodology for the design of prolyl oligopeptidase substrates

scientific article

Exploring the interaction of the surfactant N-terminal domain of gamma-Zein with soybean phosphatidylcholine liposomes

scientific article published on 01 February 2004

Fast atom bombardment mass spectrometry of protected peptide segments

scientific article published on 01 June 1988

Fine structure study of Aβ1-42 fibrillogenesis with atomic force microscopy

scientific article published on 26 May 2005

Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers

scientific article

Folding and self-assembling with beta-oligomers based on (1R,2S)-2-aminocyclobutane-1-carboxylic acid

scientific article published on 3 December 2009

From venoms to BBB shuttles: Synthesis and blood-brain barrier transport assessment of apamin and a nontoxic analog

scientific article published in November 2013

From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom

scientific article published on 01 November 2018

Functional Mimicry of a Discontinuous Antigenic Site by a Designed Synthetic Peptide

scientific article published on 01 March 2002

Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies.

scientific article published in November 2010

Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis

scientific article published on 11 October 2008

Gold nanoparticles for selective and remote heating of β-amyloid protein aggregates

HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles

scientific article published in Scientific Reports

Highly efficient, nonpeptidic oligoguanidinium vectors that selectively internalize into mitochondria

scientific article

Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response

scientific article

How Changes in the Sequence of the Peptide CLPFFD-NH2Can Modify the Conjugation and Stability of Gold Nanoparticles and Their Affinity for β-Amyloid Fibrils

scientific article published on 30 May 2008

IB-01212, a new cytotoxic cyclodepsipeptide isolated from the marine fungus Clonostachys sp. ESNA-A009.

scientific article published in April 2006

Identification by 19F NMR of traditional Chinese medicinal plants possessing prolyl oligopeptidase inhibitory activity

scientific article published in May 2006

Immunosilencing peptides by stereochemical inversion and sequence reversal: retro-D-peptides

scientific article published on 24 April 2018

Improved Fmoc‐based solid‐phase synthesis of homologous peptide fragments of human and mouse prion proteins ⬇️

scientific article published on September 16, 2010

Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide

In vitro evaluation of caffeoyl and cinnamoyl derivatives as potential prolyl oligopeptidase inhibitors

scientific article published in October 2013

Increased immune cell infiltration in patient-derived tumor explants treated with Traniplatin: an original Pt(iv) pro-drug based on Cisplatin and Tranilast

scientific article published on 01 July 2018

Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

scientific article published on 20 April 2015

Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids.

scientific article published in March 2004

Inhibitory effect of verbascoside isolated from Buddleja brasiliensis Jacq. ex Spreng on prolyl oligopeptidase activity

scientific article published on 25 January 2012

Inorganic nanoparticles and the immune system: detection, selective activation and tolerance

Intracellular Fate of Peptide-Mediated Delivered Cargoes ⬇️

scientific article published on January 1, 2013

In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii.

scientific article published on 14 June 2011

Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein

scientific article

Josef Rudinger Memorial Lecture: Use of peptides to modulate protein-protein interactions

scientific article published on 7 April 2015

Jumping Hurdles: Peptides Able To Overcome Biological Barriers

scientific article

Kahalalide B. Synthesis of a natural cyclodepsipeptide

Kinetic analyis of the carboxypeptidase a hydrolysis of oligopeptides by reversed-phase high-performance liquid chromatography

scientific article published on 01 September 1989

Knitting and untying the protein network: modulation of protein ensembles as a therapeutic strategy

scientific article published on March 2009

Light-regulated stapled peptides to inhibit protein-protein interactions involved in clathrin-mediated endocytosis

scientific article published on 17 June 2013

Lipid bilayer crossing--the gate of symmetry. Water-soluble phenylproline-based blood-brain barrier shuttles

scientific article

Loss of LPS is involved in the virulence and resistance to colistin of colistin-resistant Acinetobacter nosocomialis mutants selected in vitro

scientific article published on 25 August 2015

Low molecular weight inhibitors of Prolyl Oligopeptidase: a review of compounds patented from 2003 to 2010.

scientific article published on 03 May 2011

Mechanism of action of and resistance to quinolones

scientific article published on 13 October 2008

Mechanism of binding of fluoroquinolones to the quinolone resistance-determining region of DNA gyrase: towards an understanding of the molecular basis of quinolone resistance.

scientific article

Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly

scientific article

Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: a comparative study with epithelial cell cultures

scientific article

MiniAp-4: A Venom-Inspired Peptidomimetic for Brain Delivery

scientific article published on 23 October 2015

Modulating protein-protein interactions: the potential of peptides

scientific article published on February 2015

Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants.

scientific article published in November 2000

Molecular cloning of cDNAs encoding a putative cell wall protein from Zea mays and immunological identification of related polypeptides

scientific article

Molecular dynamics study of kaliotoxin in water.

scientific article

Molecular recognition at protein surface in solution and gas phase: Five VEGF peptidic ligands show inverse affinity when studied by NMR and CID-MS.

scientific article published on January 2010

Molecular recycling within amyloid fibrils

scientific article

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles

scientific article published in March 2010

NMR analysis of G-protein betagamma subunit complexes reveals a dynamic G(alpha)-Gbetagamma subunit interface and multiple protein recognition modes

scientific article

NMR studies of protein-ligand interactions

scientific article published on 01 January 2012

NMR-based methods and strategies for drug discovery.

scientific article

NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides I : Synthesis of the supports and their application to oligonucleotide synthesis

NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides II. Synthesis of protected peptides

Nanoparticle-Mediated Local and Remote Manipulation of Protein Aggregation

scientific article published on 01 January 2006

New Nomenclature for Complex Cyclopeptides

Non-additive effects of multiple amino acid substitutions on antigen-antibody recognition

scholarly article by Mauricio G. Mateu et al published June 1992 in European Journal of Immunology

Novel peptidyl aryl vinyl sulfones as highly potent and selective inhibitors of cathepsins L and B.

scientific article

Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery

scientific article published in February 2009

On the Role of Flexibility in Protein-Ligand Interactions: the Example of p53 Tetramerization Domain

article

PEG-PGA enveloped octaarginine-peptide nanocomplexes: An oral peptide delivery strategy

scientific article published on 5 March 2018

Peptide POP inhibitors for the treatment of the cognitive symptoms of schizophrenia

scientific article published on September 2013

Peptide and amide bond-containing dendrimers

scientific article

Peptide dendrimers based on polyproline helices

scientific article

Peptide multifunctionalized gold nanorods decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease

scientific article published on 30 June 2017

Peptides Targeting EGF Block the EGF-EGFR Interaction

scientific article published on 16 December 2015

Peptides and proteins used to enhance gold nanoparticle delivery to the brain: preclinical approaches

scientific article

Peptides conjugated to gold nanoparticles induce macrophage activation

scientific article published on 08 November 2008

Perspectives on NMR in drug discovery: a technique comes of age

scientific article

Potential peptide carriers: amphipathic proline-rich peptides derived from the N-terminal domain of gamma-zein

scientific article published in March 2004

Preparation of de novo globular proteins based on proline dendrimers

scientific article published in August 2005

Primary structure, recombinant expression and homology modelling of human brain prolyl oligopeptidase, an important therapeutic target in the treatment of neuropsychiatric diseases

scientific article

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

scientific article published in May 2002

Proline-rich, amphipathic cell-penetrating peptides

scientific article

Protein Chemical Synthesis Combined with Mirror-Image Phage Display Yields d-Peptide EGF Ligands that Block the EGF-EGFR Interaction

scientific article published on 22 July 2019

Proteomic analysis of a fraction enriched in cell envelope proteins of Acinetobacter baumannii.

scientific article

Proteomic analysis of prodigiosin-induced apoptosis in a breast cancer mitoxantrone-resistant (MCF-7 MR) cell line

scientific article published in February 2007

Racemization in suzuki couplings: a quantitative study using 4-hydroxyphenylglycine and tyrosine derivatives as probe molecules

scientific article published on 01 February 2007

Rational design of a selective covalent modifier of G protein βγ subunits

scientific article

Rational dissection of binding surfaces for mimicking of discontinuous antigenic sites.

scientific article

Reactivity with monoclonal antibodies of viruses from an episode of foot-and-mouth disease

scientific article published on 01 September 1987

Recent patents of dipeptidyl peptidase IV inhibitors

scientific article

Recognition and Stabilization of an α-Helical Peptide by a Synthetic Receptor

scientific article published in 1997

Redesign of protein domains using one-bead-one-compound combinatorial chemistry

scientific article

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer's disease.

scientific article published on 6 March 2014

Relationship between mutations in the gyrA gene and quinolone resistance in clinical isolates of Corynebacterium striatum and Corynebacterium amycolatum

scientific article

Relevant elements of a maize gamma-zein domain involved in protein body biogenesis

scientific article

Replacement of a Proline with Silaproline Causes a 20-Fold Increase in the Cellular Uptake of a Pro-Rich Peptide

scientific article published in 2006

Retro-enantio N-methylated peptides as beta-amyloid aggregation inhibitors

scientific article

Reversed-phase high-performance liquid chromatography of protected peptide segments

scientific article published on 01 November 1987

Reversible protection of lysine to facilitate the purification of protected peptide segments

S-2-(2,4-dinitrophenyl)ethyl--cysteine: a new derivative for solid-phase peptide synthesis

S-Phenylacetamidomethyl (Phacm): an orthogonal cysteine protecting group for Boc and Fmoc solid-phase peptide synthesis strategies

Saturated resins or stress of the resin

Selenomethionine incorporation into amyloid sequences regulates fibrillogenesis and toxicity

scientific article

Self-assembly of DNA-peptide supermolecules: Coiled-coil peptide structures templated by D-DNA and L-DNA triplexes exhibit chirality-independent but orientation-dependent stabilizing cooperativity

scientific article published on 05 February 2020

Self-assembly of a cyclobutane beta-tetrapeptide to form nanosized structures

scientific article published in 2007

Self-assembly of the amphipathic helix (VHLPPP)8. A mechanism for zein protein body formation11Edited by W. Baumeister

Sequence-activity relationship, and mechanism of action of mastoparan analogues against extended-drug resistant Acinetobacter baumannii

scientific article published on 9 June 2015

Severe side-reaction in the acidolytic cleavage of a C-terminal Met-containing peptide from the solid support. Formation of the homoserine lactone peptide

Shuttle-mediated drug delivery to the brain

scientific article published on 30 June 2011

Shuttling gold nanoparticles into tumoral cells with an amphipathic proline-rich peptide

scientific article

Simple methods for the preparation of protected derivatives of and

Simultaneous (19)F NMR screening of prolyl oligopeptidase and dipeptidyl peptidase IV inhibitors

scientific article published in May 2010

Small peptide inhibitors disrupt a high-affinity interaction between cytoplasmic dynein and a viral cargo protein.

scientific article

Solid-phase syntheses of N-substituted carbamates. Reaction monitoring by gel-phase 13C NMR using a 13C enriched BAL-linker

Solid-phase synthesis and characterization of N-methyl-rich peptides.

scientific article published in February 2005

Solid-phase synthesis of peptides using allylic anchoring groups 2. Palladium-catalysed cleavage of Fmoc-protected peptides

scholarly article by Paul Lloyd-Williams et al published June 1994 in Tetrahedron Letters

Solid-phase synthesis of peptides using allylic anchoring groups. An investigation of their palladium-catalysed cleavage

scholarly article by Paul Lloyd-Williams et al published August 1991 in Tetrahedron Letters

Solid-phase synthesis of second-generation polyproline dendrimers

scientific article published in January 2004

Solid-phase synthesis of “head-to-tail” cyclic peptides via lysine side-chain anchoring

Solid-phase total synthesis of trunkamide A(1).

scientific article published in November 2001

Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery

scientific article

Solid-phase-mediated peptide heterodisulfide formation

scientific article published in 1990

Solution structure of the antitumor candidate trunkamide A by 2D NMR and restrained simulated annealing methods

scientific article published in January 2003

Solution versus solid-phase cyclization strategies for large sidechain lactam-bridged peptides: a comparative study

scientific article published on 01 July 1995

Spirolactams as conformationally restricted pseudopeptides: synthesis and conformational analysis

scientific article published in November 2002

Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand

scholarly article

Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability

scientific article published on 6 May 2013

Staple Motifs, Initial Steps in the Formation of Thiolate-Protected Gold Nanoparticles: How Do They Form?

scientific article published on 10 October 2012

Steady-state dqf-cosy spectra using a variable relaxation delay

Structural analysis of substance P using molecular dynamics and NMR spectroscopy

scientific article

Structural, kinetic and cytotoxicity aspects of 12-28 beta-amyloid protein fragment: a reappraisal

Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange

scientific article published in August 2010

Structure-activity relationship of kahalalide F synthetic analogues

scientific article

Supramolecular properties of the proline-rich gamma-Zein N-terminal domain

scientific article published on August 2002

Surface Recognition and Helix Stabilization of a Tetraaspartate Peptide by Shape and Electrostatic Complementarity of an Artificial Receptor

scientific article published in 1999

Synthesis and NMR structure of p41icf, a potent inhibitor of human cathepsin L

scientific article (publication date: 12 February 2003)

Synthesis and antitumor evaluation of new thiazolo[5,4-b]quinoline derivatives

scientific article published on 01 February 1997

Synthesis and applications of a new base-labile fluorene derived linker for solid-phase peptide synthesis

Synthesis and ion-binding properties of an immobilized bis-cysteine peptide

scientific article published in 1992

Synthesis and screening of a small library of proline-based biodendrimers for use as delivery agents

scientific article published in January 2005

Synthesis and structure determination of kahalalide F (1,2).

scientific article published in November 2001

Synthesis of 3-aminolactams as X-Gly constrained pseudodipeptides and conformational study of a Trp-Gly surrogate

scientific article

Synthesis of an Orthogonally Protected Polyhydroxylated Cyclopentene from l-Sorbose

scientific article

Synthesis of aspartimide-free protected peptides on base-labile functionalized resins

Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal sequence

Synthesis of derivatives of (2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoic acid, a constituent of the didemnins

Synthesis of peptides containing α, β-didehydroamino acids. Scope and limitations

Synthesis, conformational analysis, and cytotoxicity of conformationally constrained aplidine and tamandarin A analogues incorporating a spirolactam beta-turn mimetic.

scientific article published in November 2004

Synthetic approaches to multivalent lipopeptide dendrimers containing cyclic disulfide epitopes of foot-and-mouth disease virus

scientific article

Synthetic ligands able to interact with the p53 tetramerization domain. Towards understanding a protein surface recognition event

scientific article published in July 2006

Synthetic studies on threonines. The preparation of protected derivatives of d-allo- and l-allo-threonine for peptide synthesis

Targeted nanoswitchable inhibitors of protein-protein interactions involved in apoptosis

scientific article published on 10 December 2018

Temperature coefficients of peptides dissolved in hexafluoroisopropanol monitor distortions of helices

Template-Assisted Lateral Growth of Amyloid-β42 Fibrils Studied by Differential Labeling with Gold Nanoparticles

scientific article published on 12 December 2011

Tentoxin as a scaffold for drug discovery. Total solid-phase synthesis of tentoxin and a library of analogues

scientific article

The GAGA protein of Drosophila is phosphorylated by CK2.

scientific article published in August 2005

The fuc1 gene product (20 kDa FUC1) of Pisum sativum has no alpha-L-fucosidase activity

scientific article published on April 2003

The natural product berberine is a human prolyl oligopeptidase inhibitor

scientific article published in March 2007

The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia

scientific article

The role of peptides in blood-brain barrier nanotechnology

scientific article

The use of the Nbb-resin for the solid-phase synthesis of peptide alkylesters and alkylamides. Synthesis of leuprolide

Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan

scientific article published on April 2015

Total Solid-Phase Synthesis of Marine Cyclodepsipeptide IB-01212

article by Luis J. Cruz et al published April 2006 in Journal of Organic Chemistry

Total Synthesis of Dehydrodidemnin B. Use of Uronium and Phosphonium Salt Coupling Reagents in Peptide Synthesis in Solution†

scientific article published on 01 January 1997

Toward an optimal blood-brain barrier shuttle by synthesis and evaluation of peptide libraries

scientific article

Towards the identification of unknown neuropeptide precursor-processing enzymes: Design and synthesis of a new family of dipeptidyl phosphonate activity probes for substrate-based protease identification

scientific article

Trishomocubane Amino Acid as a β-turn scaffold

Two short peptides including segments of subunit A of Escherichia coli DNA gyrase as potential probes to evaluate the antibacterial activity of quinolones

scientific article published in January 2001

Unequivocal synthesis and characterization of a parallel and an antiparallel bis-cystine peptide

Unveiling prolyl oligopeptidase ligand migration by comprehensive computational techniques.

scientific article published on January 2015

Use of Alloc-amino acids in solid-phase peptide synthesis. Tandem deprotection-coupling reactions using neutral conditions

Use of BOP reagent for the suppression of diketopiperazine formation in boc/bzl solid-phase peptide synthesis

Use of N-tritylamino acids and PyAOP1 for the suppression of diketopiperazine formation in Fmoc/tBu solid-phase peptide synthesis using alkoxybenzyl ester anchoring linkages

article published in 1996

Use of histidine pKa changes to study peptide-DNA interactions

Use of substituted and tandem-repeated peptides to probe the relevance of the highly conserved RGD tripeptide in the immune response against foot-and-mouth disease virus.

scientific article

Use of the SPhos ligand to suppress racemization in arylpinacolboronate ester Suzuki couplings involving alpha-amino acids. Synthesis of biaryl derivatives of 4-hydroxyphenylglycine, tyrosine, and tryptophan

scientific article published in December 2009

Using peptides to increase transport across the intestinal barrier

scientific article published on 4 May 2016

Using peptidyl aldehydes in activity-based proteomics.

scientific article published on 6 May 2009

d-Polyarginine Lipopeptides as Intestinal Permeation Enhancers

scientific article published on 20 August 2018

Paulina is supported by:

About Paulina

Help