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List of works by Matthias Epple

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

scientific article (publication date: April 2016)

3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study.

scientific article published on 11 June 2018

A Critical Review of Modern Concepts for Teeth Whitening

scientific article published on 01 August 2019

A Tumor-Peptide-Based Nanoparticle Vaccine Elicits Efficient Tumor Growth Control in Antitumor Immunotherapy

scientific article published on 08 April 2019

A bioactive nano-calcium phosphate paste for in-situ transfection of BMP-7 and VEGF-A in a rabbit critical-size bone defect: results of an in vivo study

scientific article published on 22 January 2019

A molecular fragment cheminformatics roadmap for mesoscopic simulation

scientific article (publication date: December 2014)

A new tool for the transfection of corneal endothelial cells: calcium phosphate nanoparticles

scientific article published on 17 September 2011

A pH-sensitive fluorescent protein sensor to follow the pathway of calcium phosphate nanoparticles into cells

scientific article published on 18 May 2020

A pH-sensitive poly(methyl methacrylate) copolymer for efficient drug and gene delivery across the cell membrane

scientific article published on 05 September 2014

A solid-state NMR investigation of the structure of nanocrystalline hydroxyapatite

scientific article

A thorough physicochemical characterisation of 14 calcium phosphate-based bone substitution materials in comparison to natural bone

scientific article published on 01 March 2004

Accumulation of silver nanoparticles by cultured primary brain astrocytes

scientific article published on 18 August 2011

Adhesion, proliferation, and osteogenic differentiation of human mesenchymal stem cells on additively manufactured Ti6Al4V alloy scaffolds modified with calcium phosphate nanoparticles

scientific article published on 18 December 2018

Amorphous and crystalline calcium carbonate distribution in the tergite cuticle of moulting Porcellio scaber (Isopoda, Crustacea).

scientific article

An Efficient Method for Covalent Surface Functionalization of Ultrasmall Metallic Nanoparticles by Surface Azidation Followed by Copper‐Catalyzed Azide‐Alkyne Cycloaddition (Click Chemistry)

scientific article published in 2021

An easy synthesis of autofluorescent alloyed silver-gold nanoparticles

scientific article published on 10 October 2014

An optimized synthetic substrate for orthodontic bond strength testing

scientific article published on 01 December 2003

Assessment of cytotoxicity and antibacterial effects of silver nanoparticle-doped titanium alloy surfaces

scientific article published on 10 July 2019

Author Correction: 3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study

scientific article published in Scientific Reports

Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivo

scientific article published on 25 May 2017

Bactericidal activity and recovery effect of hydroxyl radicals generated by ultraviolet irradiation and silver ion application on an infected titanium surface

scientific article published on 22 May 2020

Barium sulfate micro- and nanoparticles as bioinert reference material in particle toxicology

scientific article published on 10 September 2016

Bimetallic silver-platinum nanoparticles with combined osteo-promotive and antimicrobial activity

scientific article published on 08 April 2019

Biomimetic Bone Substitution Materials

chapter

Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help

scientific article published on 27 September 2019

Calcium phosphate coating of nickel-titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets

scientific article published in September 2003

Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization

scientific article published on 31 July 2008

Calcium phosphate increases the encapsulation efficiency of hydrophilic drugs (proteins, nucleic acids) into poly(d,l-lactide-co-glycolide acid) nanoparticles for intracellular delivery

scientific article published on 24 September 2014

Calcium phosphate nanoparticle-mediated transfection in 2D and 3D mono- and co-culture cell models

scientific article published on 29 November 2018

Calcium phosphate nanoparticles carrying BMP-7 plasmid DNA induce an osteogenic response in MC3T3-E1 pre-osteoblasts.

scientific article published on 19 June 2015

Calcium phosphate nanoparticles for the transfection of cells

scientific article published on January 2009

Calcium phosphate nanoparticles show an effective activation of the innate immune response in vitro and in vivo after functionalization with flagellin

scientific article published on 26 December 2013

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release.

scientific article published on 20 December 2017

Cell-biological effects of zinc oxide spheres and rods from the nano- to the microscale at sub-toxic levels

scientific article published on 17 November 2020

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

scientific article published on 12 May 2011

Characterization of crocodile teeth: correlation of composition, microstructure, and hardness

scientific article published in October 2013

Click Chemistry on the Surface of Ultrasmall Gold Nanoparticles (2 nm) for Covalent Ligand Attachment Followed by NMR Spectroscopy

scientific article published on 06 May 2019

Coating of cochlear implant electrodes with bioactive DNA-loaded calcium phosphate nanoparticles for the local transfection of stimulatory proteins

scientific article published in 2021

Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo

scientific article published on 14 December 2015

Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

scientific article

Comparative Study of the Structure, Properties, and Corrosion Behavior of Sr-Containing Biocoatings on Mg0.8Ca

scientific article published on 20 April 2020

Comparative biological effects of spherical noble metal nanoparticles (Rh, Pd, Ag, Pt, Au) with 4-8 nm diameter

scientific article published on 29 October 2018

Comparison of different methods to study effects of silver nanoparticles on the pro- and antioxidant status of human keratinocytes and fibroblasts.

scientific article published on 20 May 2016

Comparison of silver nanoparticles stored under air or argon with respect to the induction of intracellular free radicals and toxic effects toward keratinocytes

scientific article

Composites of fluoroapatite and methylmethacrylate-based polymers (PMMA) for biomimetic tooth replacement

scientific article

Conjugation of thiol-terminated molecules to ultrasmall 2 nm-gold nanoparticles leads to remarkably complex 1H-NMR spectra

scientific article published on 04 March 2016

Continuous preparation of functionalised calcium phosphate nanoparticles with adjustable crystallinity

Controlling the surface functionalization of ultrasmall gold nanoparticles by sequence-defined macromolecules

scientific article published on 22 September 2020

Cover Feature: Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper‐Catalysed and by Strain‐Promoted Azide‐Alkyne Click Chemistry (ChemNanoMat 4/2019)

scientific article published in 2019

Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal instillation in rats

scientific article (publication date: 19 December 2013)

Cytotoxicity of doxorubicin-conjugated poly[-(2-hydroxypropyl)methacrylamide]-modified γ-FeO nanoparticles towards human tumor cells

scientific article published on 25 September 2018

Deciphering the Surface Composition and the Internal Structure of Alloyed Silver-Gold Nanoparticles

scientific article published on 19 June 2018

Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulation.

scientific article published on 26 September 2017

Delivery of the autofluorescent protein R-phycoerythrin by calcium phosphate nanoparticles into four different eukaryotic cell lines (HeLa, HEK293T, MG-63, MC3T3): Highly efficient, but leading to endolysosomal proteolysis in HeLa and MC3T3 cells

scientific article

Dental pulp stem cells in chitosan/gelatin scaffolds for enhanced orofacial bone regeneration

scientific article published on 07 December 2018

Effect of silver nanoparticles on human mesenchymal stem cell differentiation

scientific article published on 10 November 2014

Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8+ T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery System

scientific article published on 01 March 2020

Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles

scientific article published on June 2006

Electrochemistry at single bimetallic nanoparticles - using nano impacts for sizing and compositional analysis of individual AgAu alloy nanoparticles

scientific article published on 15 September 2016

Electron microscopy and 3D microtomography of biominerals and biomaterials

scientific article published in 2003

Enhanced dissolution of silver nanoparticles in a physical mixture with platinum nanoparticles based on the sacrificial anode effect

scientific article published on 16 October 2019

Fetuin-A and albumin alter cytotoxic effects of calcium phosphate nanoparticles on human vascular smooth muscle cells

scientific article

Front Cover: An Efficient Method for Covalent Surface Functionalization of Ultrasmall Metallic Nanoparticles by Surface Azidation Followed by Copper‐Catalyzed Azide‐Alkyne Cycloaddition (Click Chemistry) (ChemNanoMat 12/2021)

scientific article published in 2021

Functional adaptations in the tergite cuticle of the desert isopod Hemilepistus reaumuri (Milne-Edwards, 1840)

scientific article published on 07 July 2020

Functionalization of titania nanotubes with electrophoretically deposited silver and calcium phosphate nanoparticles: Structure, composition and antibacterial assay

scientific article published on 15 December 2018

Functionally graded materials for biomedical applications

Gene silencing of the pro-inflammatory cytokine TNF-α with siRNA delivered by calcium phosphate nanoparticles, quantified by different methods

scientific article published on 24 August 2015

Gene transfection achieved by utilizing antibacterial calcium phosphate nanoparticles for enhanced regenerative therapy

scientific article published on 06 November 2020

Gene transfection of human mesenchymal stem cells with a nano-hydroxyapatite-collagen scaffold containing DNA-functionalized calcium phosphate nanoparticles.

scientific article published on 30 May 2016

Genetic immunization against hepatitis B virus with calcium phosphate nanoparticles in vitro and in vivo

scientific article published on 25 April 2020

Hybrid biocomposites based on titania nanotubes and a hydroxyapatite coating deposited by RF-magnetron sputtering: Surface topography, structure, and mechanical properties

Hybrid chitosan/gelatin/nanohydroxyapatite scaffolds promote odontogenic differentiation of dental pulp stem cells and in vitro biomineralization

scientific article published on 15 November 2020

Immobilization of cesium from aqueous solution using nanoparticles of synthetic calcium phosphates

scientific article published on 24 July 2018

Immunization with biodegradable nanoparticles efficiently induces cellular immunity and protects against influenza virus infection

scientific article published on 10 May 2013

In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

scientific article

In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT

scientific article published on 03 April 2020

Incorporation of silver nanoparticles into magnetron-sputtered calcium phosphate layers on titanium as an antibacterial coating

scientific article published on 9 May 2017

Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral Infection.

scientific article

Induction of herpes simplex virus type 1 cell-to-cell spread inhibiting antibodies by a calcium phosphate nanoparticle-based vaccine

scientific article published on 27 December 2018

Inhibition of PMN apoptosis after adherence to dip-coated calcium phosphate surfaces on a NiTi shape memory alloy

scientific article published in August 2004

Inorganic nanoparticles as carriers of nucleic acids into cells

scientific article published on January 2008

Interaction of dermatologically relevant nanoparticles with skin cells and skin

scientific article published on 8 December 2014

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer.

scientific article published on 22 September 2017

Large-area, uniform, high-spatial-frequency ripples generated on silicon using a nanojoule-femtosecond laser at high repetition rate

scientific article published on January 15, 2011

Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation

scientific article published on 8 August 2017

Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cells

scientific article

Mesoscopic simulation of phospholipid membranes, peptides, and proteins with molecular fragment dynamics

scientific article published on 05 May 2015

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

scientific article (publication date: 26 August 2014)

Mineral in skeletal elements of the terrestrial crustacean Porcellio scaber: SRμCT of function related distribution and changes during the moult cycle

scientific article published on 8 June 2016

Mineralization of the vertebral bodies inAtlantic salmon (Salmo salarL.) is initiated segmentally in the form of hydroxyapatite crystal accretions in the notochord sheath

scientific article (publication date: August 2013)

Molecular fragment dynamics study on the water-air interface behavior of non-ionic polyoxyethylene alkyl ether surfactants

scientific article published on 13 August 2013

Molecular fragment dynamics study on the water-air interface behavior of non-ionic polyoxyethylene alkyl ether surfactants.

scientific article published on 11 March 2014

Molecular simulations of peptides and proteins with Molecular Fragment Dynamics (MFD)

Morphological characterization and in vitro biocompatibility of a porous nickel-titanium alloy

scientific article published on 26 April 2005

Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence imaging and photodynamic therapy

scientific article published on 19 December 2014

NR8383 rat macrophages can induce migration of differentiated HL-60 cells following challenge with TIO2, SIO2 or carbon black

scholarly article by Götz A. Westphal et al published September 2014 in Toxicology Letters

Nanoparticle-Protein Interactions: Therapeutic Approaches and Supramolecular Chemistry.

scientific article

Nanoparticle-based B-cell targeting vaccines: Tailoring of humoral immune responses by functionalization with different TLR-ligands.

scientific article

Nanoparticle-mediated gene transfer from electrophoretically coated metal surfaces.

scientific article published on 13 July 2012

Nanoparticulate versus ionic silver: Behavior in the tank water, bioaccumulation, elimination and subcellular distribution in the freshwater mussel Dreissena polymorpha

scientific article published on 26 December 2016

Nanoscopic Porous Iridium/Iridium Dioxide Superstructures (15 nm): Synthesis and Thermal Conversion by In Situ Transmission Electron Microscopy

scientific article published on 01 August 2019

New Tools to Probe the Protein Surface: Ultrasmall Gold Nanoparticles Carry Amino Acid Binders

scientific article published on 23 December 2020

On the Crystallography of Silver Nanoparticles with Different Shapes

scholarly article by Jens Helmlinger et al published 3 June 2016 in Crystal Growth & Design

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

scientific article

Particle-induced cell migration assay (PICMA): A new in vitro assay for inflammatory particle effects based on permanent cell lines

scientific article

Peculiarities in thermal evolution of precipitated amorphous calcium phosphates with an initial Ca/P ratio of 1:1.

scientific article published on 14 February 2017

Piezoelectric 3-D Fibrous Poly(3-hydroxybutyrate)-Based Scaffolds Ultrasound-Mineralized with Calcium Carbonate for Bone Tissue Engineering: Inorganic Phase Formation, Osteoblast Cell Adhesion, and Proliferation

scientific article published on 17 May 2019

Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales

article

Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices

scientific article

Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds

scientific article published on 23 June 2018

Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection.

scientific article

Quantitative Replacement of Citrate by Phosphane on Silver Nanoparticle Surfaces Monitored by Surface-Enhanced Raman Spectroscopy (SERS).

scientific article published on February 2015

Quantitative determination of the composition of multi-shell calcium phosphate–oligonucleotide nanoparticles and their application for the activation of dendritic cells

scientific article published on July 14, 2011

RF magnetron sputtering of a hydroxyapatite target: A comparison study on polytetrafluorethylene and titanium substrates

scholarly article by Roman A. Surmenev et al published August 2017 in Applied Surface Science

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

article

Reduction of inflammation in a chronic periodontitis model in rats by TNF-α gene silencing with a topically applied siRNA-loaded calcium phosphate paste

scientific article published on 23 January 2020

Reply to the ‘Comments on “Dental lessons from past to present: ultrastructure and composition of teeth from plesiosaurs, dinosaurs, extinct and recent sharks”’ by H. Botella et al., RSC Adv., 2016,<b>6</b>, 74384–74388

scientific article published in 2017

SPICES: a particle-based molecular structure line notation and support library for mesoscopic simulation

scientific article published on 09 August 2018

Shape-Dependent Dissolution and Cellular Uptake of Silver Nanoparticles.

scientific article

SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing.

scientific article published on 21 May 2010

Silver as antibacterial agent: ion, nanoparticle, and metal

scientific article published on 17 December 2012

Silver-doped calcium phosphate nanoparticles: synthesis, characterization, and toxic effects toward mammalian and prokaryotic cells.

scientific article

Skeletal deformations in medaka (Oryzias latipes) visualized by synchrotron radiation micro-computer tomography (SRmicroCT).

scientific article published on 25 August 2007

Solution NMR Spectroscopy with Isotope-Labeled Cysteine (13C and 15N) Reveals the Surface Structure of l-Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)

scientific article published on 04 January 2019

Structure of Biocompatible Coatings Produced from Hydroxyapatite Nanoparticles by Detonation Spraying

scientific article

Structure, composition, and mechanical properties of shark teeth

scientific article

Synthesis and characterization of PLGA/HAP scaffolds with DNA-functionalised calcium phosphate nanoparticles for bone tissue engineering

scientific article published on 02 November 2020

Synthesis, characterization and in vitro effects of 7 nm alloyed silver-gold nanoparticles

scientific article published on 27 May 2015

Synthetic pathways to make nanoparticles fluorescent

scientific article published on 07 March 2011

Targeting and activation of antigen-specific B-cells by calcium phosphate nanoparticles loaded with protein antigen

scientific article published on 26 April 2014

Targeting the surface of the protein 14-3-3 by ultrasmall gold nanoparticles (1.5 nm), carrying the specific peptide CRaf

scientific article published on 04 December 2020

Teeth of Past and Present Elephants: Microstructure and Composition of Enamel in Fossilized Proboscidean Molars and Implications for Diagenesis

scientific article published in 2021

The potential of nanoparticles for the immunization against viral infections

scientific article published on 21 May 2015

The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunization

scientific article published on 27 August 2013

The use of calcium phosphate nanoparticles encapsulating Toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activation

scientific article

The use of size-defined DNA-functionalized calcium phosphate nanoparticles to minimise intracellular calcium disturbance during transfection.

scientific article published on 18 September 2009

Thermally induced crystallization and phase evolution in powders derived from amorphous calcium phosphate precipitates with a Ca/P ratio of 1:1

Tracking the pathway of calcium phosphate/DNA nanoparticles during cell transfection by incorporation of red-fluorescing tetramethylrhodamine isothiocyanate-bovine serum albumin into these nanoparticles

scientific article published on 10 October 2006

Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model

scientific article published on 22 October 2020

Ultrasmall gold and silver/gold nanoparticles (2 nm) as autofluorescent labels for poly(D,L-lactide-co-glycolide) nanoparticles (140 nm)

scientific article published on 28 November 2020

Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model

scientific article published on 12 May 2020

Ultrastructural organization and micromechanical properties of shark tooth enameloid

scientific article published on 4 May 2014

Ultrastructure and mineral distribution in the tergal cuticle of the terrestrial isopod Titanethes albus. Adaptations to a karst cave biotope.

scientific article published on 24 July 2009

Ultrastructure and mineral distribution in the tergite cuticle of the beach isopod Tylos europaeus Arcangeli, 1938.

scientific article

Upregulation of metallothioneins after exposure of cultured primary astrocytes to silver nanoparticles

scientific article

Zn- or Cu-Containing CaP-Based Coatings Formed by Micro-arc Oxidation on Titanium and Ti-40Nb Alloy: Part I-Microstructure, Composition and Properties

scientific article published on 16 September 2020

miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin

scientific article