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List of works by Carsten Carlberg

1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.

scientific article published on December 2011

1α,25-Dihydroxyvitamin D3 receptor as a mediator of transrepression of retinoid signaling ⬇️

scientific article published on December 1, 1997

25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand

scientific article

A Role for the PPARgamma in Cancer Therapy.

scientific article published on January 2008

A functional approach to the mapping of structural polymorphisms in superhelical DNA.

scientific article published in May 1988

A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors

scientific article published on 19 July 2005

A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling.

scientific article published on August 2004

Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs

scientific article

Agonist-triggered modulation of the activated and silent state of the vitamin D(3) receptor by interaction with co-repressors and co-activators

scientific article published on 01 December 2000

All natural DR3-type vitamin D response elements show a similar functionality in vitro

scientific article published on December 2000

Allosteric interaction of the 1 ,25-dihydroxyvitamin D3 receptor and the retinoid X receptor on DNA ⬇️

scientific article published on November 1, 1997

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

scientific article published on 03 December 2019

An integrated biological approach to nuclear receptor signaling in physiological control and disease.

scientific article

Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site

scientific article

Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein

scientific article published on 19 May 2005

Antagonistic action of a 25-carboxylic ester analogue of 1alpha, 25-dihydroxyvitamin D3 is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators

scientific article (publication date: 2 June 2000)

Carboxylic ester antagonists of 1alpha,25-dihydroxyvitamin D(3) show cell-specific actions.

scientific article

Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene.

scientific article

Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.

scientific article

Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

scientific article

Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor

scientific article published in August 2003

Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening

scientific article

Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression

scientific article

Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood

scientific article published on 03 December 2020

Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling

scientific article

Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites

scientific article published on 16 January 2007

Coordinate induction of PPAR alpha and SREBP2 in multifunctional protein 2 deficient mice

scientific article

Corepressor excess shifts the two-side chain vitamin D analog Gemini from an agonist to an inverse agonist of the vitamin D receptor

scientific article published on 3 July 2003

Corrigendum to “Primary effect of 1α,25(OH)2D3 on IL-10 expression in monocytes is short-term down-regulation” [Biochim. Biophys. Acta 1803 (2010) 1276–86]

scholarly article by Juha M. Matilainen published in December 2011

Critical role of helix 12 of the vitamin D(3) receptor for the partial agonism of carboxylic ester antagonists

scientific article published in January 2002

Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors

scientific article

Current status of vitamin D signaling and its therapeutic applications

scientific article published on January 2012

Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1alpha,25-dihydroxyvitamin D3.

scientific article published on 03 January 2009

Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3.

scientific article published on 19 September 2010

DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.

scientific article

Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes

scientific article

Design principles of nuclear receptor signaling: how complex networking improves signal transduction.

scientific article

Design principles of nuclear receptor signalling: How complex networking improves signal transduction

article

Detailed molecular understanding of agonistic and antagonistic vitamin D receptor ligands.

scientific article published on January 2006

Differential apoptotic response of human melanoma cells to 1 alpha,25-dihydroxyvitamin D3 and its analogues.

scientific article

Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes

scientific article published on 24 June 2011

Differential nuclear receptor signalling from DR4-type response elements

scientific article

Dissecting high from low responders in a vitamin D3 intervention study

scientific article published on 13 November 2014

Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and 1alpha,25-dihydroxyvitamin D3.

scientific article published on 13 November 2007

Dynamic nature of transcriptional regulation of nuclear receptor target genes in the context of chromatin organization.

scientific article published on July 2011

Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes

scientific article published on November 2013

Dynamics of nuclear receptor target gene regulation.

scientific article published on 13 July 2010

ETS transcription factor family member GABPA contributes to vitamin D receptor target gene regulation

scientific article published in September 2017

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study

scientific article published on 17 March 2016

Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)

scientific article published on 26 February 2014

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

scientific article

Endocrine functions of vitamin D

scientific article published on 29 June 2017

Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells

scientific article

Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF.

scientific article published on 28 December 2015

Epigenomic PU.1-VDR crosstalk modulates vitamin D signaling.

scientific article published on 14 February 2017

Fluorescence resonance energy transfer analysis of the structure of the four-way DNA junction

scientific article published on 01 May 1992

From pharmacogenomics to integrated personal omics profiling: a gap in implementation into healthcare

scientific article published on 01 September 2014

Functional characterization of a novel type of 1 alpha,25-dihydroxyvitamin D3 response element identified in the mouse c-fos promoter

scientific article published on 01 January 1997

Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene

scientific article published on 19 April 2007

Functional conformations of the nuclear 1α,25-dihydroxyvitamin D3 receptor ⬇️

scientific article published on October 15, 1997

Gene regulation by vitamin D3.

scientific article

Gene regulatory potential of nonsteroidal vitamin D receptor ligands

scientific article published on 28 April 2005

Gene regulatory scenarios of primary 1,25-dihydroxyvitamin d3 target genes in a human myeloid leukemia cell line

scientific article published on 16 October 2013

Genome-wide (over)view on the actions of vitamin D

scientific article

Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages.

scientific article

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

scientific article

High-affinity nuclear receptor binding of 20-epi analogues of 1,25-dihydroxyvitamin D3 correlates well with gene activation

scientific article published on 01 September 1996

Highlights from the 5th International Conference on Vitamin D Deficiency, Nutrition and Human Health, Abu Dhabi, United Arab Emirates, March 24-25, 2016.

scientific article published on 27 April 2017

Highlights from the 6th International Conference on Vitamin D Deficiency, "Nutrition and Human Health", Abu Dhabi, United Arab Emirates, March 9-10, 2017

scientific article published on 01 June 2018

Identification and characterization of a vitamin D3 response element of chicken carbonic anhydrase-II.

scientific article published on December 1994

Identification of a vitamin D receptor homodimer-type response element in the rat calcitriol 24-hydroxylase gene promoter.

scientific article published on August 1994

Identification of natural monomeric response elements of the nuclear receptor RZR/ROR. They also bind COUP-TF homodimers

scientific article published on 01 August 1996

Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis.

scientific article published on 5 January 2005

Identification of two activating elements in the proximal promoter region of the human glutathione transferase-A1 and -A2 genes

scientific article published on 01 November 1998

Impact of Epigenetics on Complications of Fanconi Anemia: The Role of Vitamin D-Modulated Immunity

scientific article published on 09 May 2020

In vivo response of the human epigenome to vitamin D: A Proof-of-principle study

scientific article published on 6 January 2018

In vivo transcriptome changes of human white blood cells in response to vitamin D

scientific article published on 08 December 2018

Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-κB pathway

scientific article published on 13 July 2012

Inhibitory effect of uremic solutions on protein-DNA-complex formation of the vitamin D receptor and other members of the nuclear receptor superfamily

scientific article published on 01 September 1999

Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-κB binding that is linked to immune phenotypes.

scientific article

Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB.

scientific article published on 15 February 2007

Key Vitamin D Target Genes with Functions in the Immune System

scientific article published on 19 April 2020

Ligand-mediated conformational changes of the VDR are required for gene transactivation

scientific article

Ligand-triggered stabilization of vitamin D receptor/retinoid X receptor heterodimer conformations on DR4-type response elements

scientific article published on 01 February 2000

Lipid soluble vitamins in gene regulation.

scientific article

Machine learning approaches infer vitamin D signaling: Critical impact of vitamin D receptor binding within topologically associated domains

scientific article published on 22 July 2018

Mechanism of 1α,25-dihydroxyvitamin D(3)-dependent repression of interleukin-12B.

scientific article published on 18 February 2011

Mechanisms of nuclear signalling by vitamin D3. Interplay with retinoid and thyroid hormone signalling

scientific article

Meta-analysis of primary target genes of peroxisome proliferator-activated receptors

scientific article

Modulation of vitamin D signaling by the pioneer factor CEBPA

scientific article published on 11 December 2018

Molecular Approaches for Optimizing Vitamin D Supplementation.

scientific article published on 30 November 2015

Molecular basis of the selective activity of vitamin D analogues

scientific article

Molecular endocrinology of vitamin D on the epigenome level.

scientific article

Molecular evaluation of vitamin D responsiveness of healthy young adults

scientific article published on 6 June 2016

Molecular mechanism of allosteric communication in the human PPARalpha-RXRalpha heterodimer

scientific article published on March 2010

Multiplex Eukaryotic Transcription (In)activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism

scientific article published on 24 April 2015

Natural vitamin D3 response elements formed by inverted palindromes: polarity-directed ligand sensitivity of vitamin D3 receptor-retinoid X receptor heterodimer-mediated transactivation.

scientific article published on March 1995

Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy

scientific article published on 16 August 2011

Nutrigenomics of Vitamin D

scientific article published on 21 March 2019

Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands

scientific article published in January 2002

Patterns of genome-wide VDR locations.

scientific article

Peroxisome proliferator-activated receptor alpha controls hepatic heme biosynthesis through ALAS1.

scientific article published on 14 March 2009

Peroxisome proliferator-activated receptor δ is a specific sensor for teratogenic valproic acid derivatives ⬇️

scientific article published on November 9, 2001

Potent gene regulatory and antiproliferative activities of 20-methyl analogues of 1,25 dihydroxyvitamin D3

scientific article published on 01 November 1996

Potentiation by vitamin D analogs of TNFalpha and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2

scientific article published on 01 September 1999

Primary 1,25-dihydroxyvitamin D3 response of the interleukin 8 gene cluster in human monocyte- and macrophage-like cells

scientific article

Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation

scientific article published on 4 August 2010

Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system

scientific article published on 24 April 2014

Primary vitamin D target genes allow a categorization of possible benefits of vitamin D₃ supplementation

scientific article

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis

scientific article published on 27 January 2010

RXR-independent action of the receptors for thyroid hormone, retinoid acid and vitamin D on inverted palindromes

scientific article published on September 1993

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

Randomized controlled trial on the effectiveness of web-based Genomics Nursing Education Intervention for undergraduate nursing students: a study protocol

scientific article published on 25 August 2020

Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3.

scientific article

Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter

scientific article

Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.

scientific article

Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling.

scientific article published on 05 May 2009

Relevance of vitamin D receptor target genes for monitoring the vitamin D responsiveness of primary human cells

scientific article

Response element selectivity for heterodimerization of vitamin D receptors with retinoic acid and retinoid X receptors.

scientific article published on June 1994

Screening for PPAR Responsive Regulatory Modules in Cancer.

scientific article published on January 2008

Selective recognition of vitamin D receptor conformations mediates promoter selectivity of vitamin D analogs

scientific article published on 01 June 1999

Selective regulation of biological processes by vitamin D based on the spatio-temporal cistrome of its receptor.

scientific article published on 13 July 2017

Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene

scientific article

Sensitive induction of apoptosis in breast cancer cells by a novel 1,25-dihydroxyvitamin D3 analogue shows relation to promoter selectivity

scientific article published on 01 September 1997

Single thyroid hormone receptor monomers are competent for co-activator-mediated transactivation

scientific article

Skin color and vitamin D: an update

scientific article published on 03 July 2020

Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3.

scientific article

Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor

scientific article published in June 2003

Structural variants of the vitamin D analogue EB1089 reduce its ligand sensitivity and promoter selectivity

scientific article published on 01 December 1998

Structure activity relationship of carboxylic ester antagonists of the vitamin D(3) receptor

scientific article published on 01 November 2000

Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis

scientific article

The 1,25-dihydroxyvitamin D3 (VD) analogues MC903, EB1089 and KH1060 activate the VD receptor: homodimers show higher ligand sensitivity than heterodimers with retinoid X receptors

scientific article published on 01 November 1994

The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in human monocytes and macrophages.

scientific article published on 31 August 2013

The Impact of Whole GenomeIn SilicoScreening for Nuclear Receptor-Binding Sites in Systems Biology

The antiproliferative effect of vitamin D3 analogues

scientific article published on 01 January 1996

The concept of the personal vitamin D response index

scientific article published on 26 December 2016

The critical role of carboxy-terminal amino acids in ligand-dependent and -independent transactivation of the constitutive androstane receptor

scientific article

The down-regulation of the human MYC gene by the nuclear hormone 1alpha,25-dihydroxyvitamin D3 is associated with cycling of corepressors and histone deacetylases.

scientific article published on 21 May 2010

The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor

scientific article published on 7 December 2012

The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alpha,25(OH)2D3 targets.

scientific article published on May 2004

The high affinity ligand binding conformation of the nuclear 1,25-dihydroxyvitamin D3 receptor is functionally linked to the transactivation domain 2 (AF-2)

scientific article published on November 1996

The impact of the vitamin D-modulated epigenome on VDR target gene regulation

scientific article published on 03 July 2018

The impact of transcriptional cycling on gene regulation.

scientific article

The induction and functions of murine T-helper cell subsets

scientific article published on 01 July 1995

The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors.

scientific article published on 24 October 2006

The need for education in personalized medicine

scientific article published on 01 March 2012

The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes.

scientific article

The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells

scientific article

The physiology of vitamin D-far more than calcium and bone

scientific article published on 2 September 2014

The potent anti-proliferative effect of 20-epi analogues of 1,25 dihydroxyvitamin D3 in human breast-cancer MCF-7 cells is related to promoter selectivity

scientific article published on 01 September 1996

The role of the T-box for the function of the vitamin D receptor on different types of response elements.

scientific article published on December 1998

The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D.

scientific article

The vitamin D receptor

scientific article published on October 2007

The vitamin D(3) receptor in the context of the nuclear receptor superfamily : The central role of the retinoid X receptor

scientific article published on 01 April 1996

The vitamin D-dependent transcriptome of human monocytes

scientific article

Thiazolidine diones, specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent antiarthritic activity.

scientific article

Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta

scientific article

Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis

scientific article

Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model.

scientific article

Two nuclear signalling pathways for vitamin D

scientific article published in Nature

VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership

scientific article published on 01 July 2000

Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance

scientific article

Vitamin D Genomics: From In Vitro to In Vivo

scientific article published on 23 May 2018

Vitamin D Signaling Suppresses Early Prostate Carcinogenesis in TgAPT121 Mice

scientific article published on 26 April 2019

Vitamin D and Its Synthetic Analogs

scientific article published on 02 April 2019

Vitamin D and cancer: effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis

scientific article

Vitamin D and evolution: Pharmacologic implications

scientific article published on 01 August 2019

Vitamin D receptor 2016: novel ligands and structural insights.

scientific article

Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket

scientific article published on 13 February 2006

Vitamin D receptor ligands: the impact of crystal structures

scientific article published on 27 March 2012

Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view

scientific article

Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes

scientific article published on 27 April 2016

Vitamin D receptor signaling mechanisms: integrated actions of a well-defined transcription factor

scientific article

Vitamin D receptor(s): in the nucleus but also at membranes?

scientific article published on 11 July 2020

Vitamin D-dependent chromatin association of CTCF in human monocytes

scientific article published on 25 August 2016

Vitamin D3-thyroid hormone receptor heterodimer polarity directs ligand sensitivity of transactivation

scientific article published on August 1994

Vitamins as hormones.

scientific article published on February 2007

cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction

scientific article published on 01 September 1994

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