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List of works by Michael R. Gold

Activation and function of the Rap1 GTPase in B lymphocytes

scientific article

Activation and phosphatidylinositol 3-kinase-dependent phosphorylation of protein kinase C-epsilon by the B cell antigen receptor

scientific article published on 01 July 2002

Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation

scientific article published in Journal of Biological Chemistry

Akt is TCL-ish: implications for B-cell lymphoma.

scientific article

Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.

scientific article published on 19 May 2016

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

scientific article published on 3 June 2019

B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.

scientific article

B-cell receptor signaling inhibitors for treatment of autoimmune inflammatory diseases and B-cell malignancies.

scientific article published on August 2013

B-lymphocyte signal transduction in response to anti-immunoglobulin and bacterial lipopolysaccharide.

scientific article published on February 1987

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages ⬇️

scientific article published on May 15, 1991

Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation.

scientific article

Control of the hippo pathway by Set7-dependent methylation of Yap.

scientific article published on 11 July 2013

Dendritic cell survival and maturation are regulated by different signaling pathways.

scientific article published on December 1998

Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

scientific article published on 17 April 2015

Examination of B lymphoid cell lines for membrane immunoglobulin-stimulated tyrosine phosphorylation and src-family tyrosine kinase mRNA expression

scientific article published on July 1, 1992

Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility

scientific article published on 12 September 2017

Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis.

scientific article published on 21 August 2009

Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells

scientific article published on 24 June 2009

New views of BCR structure and organization.

scientific article published in June 2001

Overview of the Alliance for Cellular Signaling

scientific article

PI3K Signaling in B Cell and T Cell Biology.

scientific article published on 3 November 2014

Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs

scientific article published on 18 May 2010

Protein kinase C-delta is a target of B-cell antigen receptor signaling

scientific article published on 01 August 1999

Real-time 3D stabilization of a super-resolution microscope using an electrically tunable lens.

scientific article

Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase

scientific article

Regulation of anti-immunoglobulin-induced B lymphoma growth arrest by transforming growth factor β1 and dexamethasone ⬇️

scientific article published on November 1, 1991

SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling

scientific article published on April 2016

Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression.

scientific article

Selective activation of p42 mitogen-activated protein (MAP) kinase in murine B lymphoma cell lines by membrane immunoglobulin cross-linking. Evidence for protein kinase C-independent and -dependent mechanisms of activation.

scientific article published on October 1992

Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice

scientific article published on 01 February 2013

Signal transduction by the B-cell antigen receptor.

scientific article published on September 1995

TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma

scientific article published on 24 February 2020

TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells

scientific article published on 29 December 2010

The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.

scientific article

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

scientific article published on November 1998

The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes

scientific article published on 01 August 2006

The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.

scientific article

The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas.

scientific article published on 19 October 2009

The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse

scientific article published on 6 February 2017

The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center.

scientific article published on 19 February 2018

The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

scientific article

The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner.

scientific article published on 11 February 2013

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

scientific article

The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands.

scientific article

To make antibodies or not: signaling by the B-cell antigen receptor

scientific article

Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

scientific article

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking ⬇️

scientific article published on April 15, 1991

What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling

scientific article published in November 2016

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