List of works - Jill Trewhella

1H N.M.R Studies of High-Spin Complexes of Soybean Leghemoglobin. Interactions Between the Distal Histidine and Acetate, Formate and Fluoride Ligands

1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis

scientific article published on 4 June 2010

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

scientific article published on 18 August 2017

A Day in the World Science Alliance

scientific article published in Science

A Structural Model of the Catalytic Subunit-regulatory Subunit Dimeric Complex of the cAMP-dependent Protein Kinase

scientific article published in Journal of Biological Chemistry

A chemically modified α-amylase with a molten-globule state has entropically driven enhanced thermal stability†

scientific article published on 09 August 2010

A model of troponin-I in complex with troponin-C using hybrid experimental data: the inhibitory region is a beta-hairpin

scientific article

A model structure of the muscle protein complex 4Ca2+.troponin C.troponin I derived from small-angle scattering data: implications for regulation.

scientific article published on November 1994

A novel approach for enhancing the catalytic efficiency of a protease at low temperature: reduction in substrate inhibition by chemical modification

scientific article published in July 2009

A novel structure of an antikinase and its inhibitor

scientific article

A picornaviral loop-to-loop replication complex.

scientific article published on 4 March 2009

Activation of Myosin Light Chain Kinase Requires Translocation of Bound Calmodulin

scientific article published in Journal of Biological Chemistry

Activation of the retroviral budding factor ALIX.

scientific article

An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis

scholarly article

Archiving of Integrative Structural Models

scientific article published on 01 January 2018

Assignment of segments of the bacteriorhodopsin sequence to positions in the structural map.

scientific article

Binding of N-Terminus Fragments of Cardiac Myosin-Binding C-protein to Actin

Book reviews

C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change

scientific article published on 25 February 2004

C-terminal domain of KipI from Bacillus subtilis

COAGULATION FACTOR, NMR, 15 STRUCTURES

COAGULATION FACTOR, NMR, 20 STRUCTURES

Ca2+-induced structural changes in phosphorylase kinase detected by small-angle X-ray scattering

scientific article

Calmodulin Binding to Myosin Light Chain Kinase Begins at Substoichiometric Ca2+Concentrations: A Small-Angle Scattering Study of Binding and Conformational Transitions†

scientific article published on 01 December 1998

Calmodulin Remains Extended upon Binding to Smooth Muscle Caldesmon: A Combined Small-Angle Scattering and Fourier Transform Infrared Spectroscopy Study†

scientific article published on 01 April 2000

Calmodulin binds a highly extended HIV-1 MA protein that refolds upon its release.

scientific article

Calmodulin disrupts the structure of the HIV-1 MA protein

scientific article

Cardiac myosin-binding protein C decorates F-actin: implications for cardiac function.

scholarly article

Changes in small-angle X-ray scattering parameters observed upon binding of ligand to rabbit muscle pyruvate kinase are not correlated with allosteric transitions

scientific article published on August 2010

Characterization of the solution structure of a neuroligin/beta-neurexin complex

scientific article published on 04 May 2008

Clinically Linked Mutations in the Central Domains of Cardiac Myosin-Binding Protein C with Distinct Phenotypes Show Differential Structural Effects

scientific article published on 30 November 2015

Coassembling Peptide-Based Biomaterials: Effects of Pairing Equal and Unequal Chain Length Oligopeptides

Conformational analysis of PKI(5-22)amide, the active inhibitory fragment of the inhibitor protein of the cyclic AMP-dependent protein kinase

scientific article published on December 1989

Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions

scientific article

Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase

scientific article

Contrast Variation

Corrigendum to “A picornaviral loop-to-loop replication complex” [J. Struct. Biol. 166 (2009) 251–262]

scholarly article published in Journal of Structural Biology

Corrigendum to “Calmodulin Disrupts the Structure of the HIV-1 MA Protein” [J. Mol. Biol. 400/4 (2010) 702–714]

article

Crystal structure of TTHA0988 in space group P43212

Denatured states of ribonuclease A have compact dimensions and residual secondary structure

article

Development of experimental techniques to study protein and nucleic acid structures

article

Differences in the heme environment of soybean leghemoglobin components shown by 1H-NMR spectroscopy

Differential effects of substrate on type I and type II PKA holoenzyme dissociation

scientific article

Domain organization of the monomeric form of the Tom70 mitochondrial import receptor

scientific article published on 7 April 2009

Dynamic Light Scattering

Editorial overview --New frontiers of biophysical methods: Tools for structural biology and beyond

scholarly article by David P Millar published in October 2014

Effect of temperature during assembly on the structure and mechanical properties of peptide-based materials

scientific article

Effects of chain length on oligopeptide hydrogelation

scientific article published on January 2011

Effects of gadolinium chelate on the evolution of the nanoscale structure in peptide hydrogels

scientific article published on 23 June 2011

Effects of macromolecular crowding on an intrinsically disordered protein characterized by small-angle neutron scattering with contrast matching

scientific article

Erratum to “Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor” [J. Mol. Biol. 388 (2009) 1043–1058]

scientific article published in July 2009

Evolution of quaternary structure in a homotetrameric enzyme

scientific article

Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures

scientific article published on 25 November 2019

Fractal dimension of an intrinsically disordered protein: small-angle X-ray scattering and computational study of the bacteriophage λ N protein

scientific article published on 26 October 2011

Further insights into calmodulin-myosin light chain kinase interaction from solution scattering and shape restoration

scientific article published on September 2003

Global Conformational Changes Control the Reactivity of Methane Monooxygenase†

scientific article published in 1999

HIV-1 Reverse Transcriptase Monomers Adopt Multiple Conformations in Solution

article

Histidine kinase regulation by a cyclophilin-like inhibitor

scientific article

Human Cardiac Myosin Binding Protein C: Structural Flexibility within an Extended Modular Architecture

article

Inelastic neutron scattering in biology

Insights into biomolecular function from small-angle scattering.

scientific article

Invited review: probing the structures of muscle regulatory proteins using small-angle solution scattering.

scientific article published on 25 March 2011

K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity

scientific article

LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States

scientific article published on 09 April 2010

Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein

scientific article published on 28 November 2007

Ligand-induced conformational changes via flexible linkers in the amino-terminal region of the inositol 1,4,5-trisphosphate receptor.

scientific article published on 29 August 2007

Light Scattering

scholarly article published in 2002

Low-angle Scattering of Neutrons and X-rays

MULCh: modules for the analysis of small-angle neutron contrast variation data from biomolecular assemblies

article

Mechanisms associated with cGMP binding and activation of cGMP-dependent protein kinase

scholarly article

Molecular basis for proton-dependent anion binding by soybean leghaemoglobin a

scientific article published in Nature

Mutation in a flexible linker modulates binding affinity for modular complexes

scientific article published on 09 March 2019

Myosin light chain kinase: functional domains and structural motifs

article

Naysaying the Neutron Scattering Society

Neutron Diffraction And Scattering

Neutron Diffraction Studies of Bacteriorhodopsin Structure

Neutron Resonance Scattering Shows Specific Binding of Plutonium to the Calcium-Binding Sites of the Protein Calmodulin and Yields Precise Distance Information

scientific article published in 1997

Neutron diffraction studies of bacteriorhodopsin

Neutron-Scattering Studies Reveal Further Details of the Ca2+/Calmodulin-Dependent Activation Mechanism of Myosin Light Chain Kinase†

article by Joanna K. Krueger et al published October 1998 in Biochemistry

Neutrons reveal how nature uses structural themes and variation in biological regulation

Ordered macromolecular structures in ferrofluid mixtures

scientific article published in Physical Review Letters

Orienting rigid and flexible biological assemblies in ferrofluids for small-angle neutron scattering studies.

scientific article

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop

scientific article published on 18 June 2015

PDB-Dev: a Prototype System for Depositing Integrative/Hybrid Structural Models

scientific article

Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin

scientific article

Potential Biophysical Application Of The Los Alamos Infrared Free Electron Laser: DNA Spectroscopy

Potential biophysical application of the Los Alamos infrared free electron laser: DNA spectroscopy

Progressive cyclic nucleotide-induced conformational changes in the cGMP-dependent protein kinase studied by small angle X-ray scattering in solution.

scientific article published in December 1997

Protein kinase A targeting and activation as seen by small-angle solution scattering

scientific article

Publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution ⬇️

scientific article published on May 17, 2012

Quaternary Structures of a Catalytic Subunit-Regulatory Subunit Dimeric Complex and the Holoenzyme of the cAMP-dependent Protein Kinase by Neutron Contrast Variation

scientific article published in Journal of Biological Chemistry

Radius Of Gyration

Refined solution structure of the 82-kDa enzyme malate synthase G from joint NMR and synchrotron SAXS restraints

scientific article

Refinement of multidomain protein structures by combination of solution small-angle X-ray scattering and NMR data

scientific article

Reflections of a Woman Scientist in the Year 2011

article

Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - the importance of quality control and a standard reporting framework ⬇️

scientific article published on May 17, 2012

Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB.

scientific article

Ritva Serimaa (1957–2016)

Scattering Intensity Distribution

Small-Angle Scattering

article from 2002

Small-Angle Scattering of Neutrons and X-Rays

Small-angle Scattering of Neutrons and X-rays

Small-angle X-ray scattering of reduced ribonuclease A: effects of solution conditions and comparisons with a computational model of unfolded proteins

scientific article published on 14 February 2008

Small-angle X-ray scattering reveals the N-terminal domain organization of cardiac myosin binding protein C.

scientific article published on 4 February 2008

Small-angle neutron scattering with contrast variation reveals spatial relationships between the three subunits in the ternary cardiac troponin complex and the effects of troponin I phosphorylation

scientific article published in July 2003

Small-angle scattering and 3D structure interpretation

scientific article

Small-angle scattering and neutron contrast variation for studying bio-molecular complexes

scientific article

Small-angle scattering for structural biology--expanding the frontier while avoiding the pitfalls.

scientific article

Sol and gel states in peptide hydrogels visualized by Gd(III)-enhanced magnetic resonance imaging

scientific article

Solution Structure of Heavy Meromyosin by Small-angle Scattering

scientific article published in Journal of Biological Chemistry

Solution Structures of Calcium Regulating Proteins: A Small-Angle Scattering Study

Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms

scientific article published on 20 January 2006

Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change

scientific article published on 14 October 2009

Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions

scientific article

Solution structure of the bisphosphorylated cardiac specific N-extension of cardiac troponin I

Solution structure of the cAMP-dependent protein kinase

Solution structure studies of monomeric human TIP47/perilipin-3 reveal a highly extended conformation.

scientific article published on 25 May 2012

Spin state equilibria in soybean ferric leghemoglobin and its complexes with formate and acetate

scientific article published on 01 May 1979

Stability of transmembrane regions in bacteriorhodopsin studied by progressive proteolysis

scientific article published on 01 January 1985

Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification

scientific article

Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1

scientific article

Structural basis of interprotein electron transfer in bacterial sulfite oxidation

scientific article published on 19 December 2015

Structural determination of larger proteins using stable isotope labeling and NMR spectroscopy

article

Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis

scientific article published in Nature Communications

Structural themes and variations in protein kinase A as seen by small-angle scattering and neutron contrast variation

Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state

scientific article

Structures of Calmodulin and a Functional Myosin Light Chain Kinase in the Activated Complex: A Neutron Scattering Study†

article by Joanna K. Krueger et al published May 1997 in Biochemistry

Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue

scientific article published on 11 July 2008

Synaptic arrangement of the neuroligin/beta-neurexin complex revealed by X-ray and neutron scattering

scientific article published on June 2007

The C0C1 fragment of human cardiac myosin binding protein C has common binding determinants for both actin and myosin

scientific article published on 28 September 2011

The N-terminal domains of myosin binding protein C can bind polymorphically to F-actin

scientific article

The Structure of the KinA-Sda Complex Suggests an Allosteric Mechanism of Histidine Kinase Inhibition

scientific article published on 03 February 2007

The Structure of the Muscle Protein Complex 4Ca2+·Troponin C·Troponin I

The assembly of immunoglobulin-like modules in titin: implications for muscle elasticity

scientific article published on 01 December 1998

The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding

scientific article published on 17 August 2005

The different views from small angles

scholarly article

The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition

scientific article

The motif of human cardiac myosin-binding protein C is required for its Ca2+-dependent interaction with calmodulin

scientific article published on 16 July 2012

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

scientific article published on 23 March 2016

The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study

scientific article

The role of heme binding by DNA-protective protein from starved cells (Dps) in the Tolerance of Porphyromonas gingivalis to heme toxicity

scientific article

The solution structure of a cardiac troponin C-troponin I-troponin T complex shows a somewhat compact troponin C interacting with an extended troponin I-troponin T component

scientific journal article

The solution structure of the DNA double-stranded break repair protein Ku and its complex with DNA: a neutron contrast variation study.

scientific article

The solution structures of calmodulin and its complexes with synthetic peptides based on target enzyme binding domains

scientific article published on June 1, 1992

The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase

scientific article

There is communication between all four Ca(2+)-bindings sites of calcineurin B.

scientific article published on October 2001

Troponin I Inhibitory Peptide (96−115) Has an Extended Conformation When Bound to Skeletal Muscle Troponin C†

scientific article published on 01 May 1999

X-Ray Scattering

scholarly article

List of works by Jill Trewhella

1H N.M.R Studies of High-Spin Complexes of Soybean Leghemoglobin. Interactions Between the Distal Histidine and Acetate, Formate and Fluoride Ligands

1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

A Day in the World Science Alliance

A Structural Model of the Catalytic Subunit-regulatory Subunit Dimeric Complex of the cAMP-dependent Protein Kinase

A chemically modified α-amylase with a molten-globule state has entropically driven enhanced thermal stability†

A model of troponin-I in complex with troponin-C using hybrid experimental data: the inhibitory region is a beta-hairpin

A model structure of the muscle protein complex 4Ca2+.troponin C.troponin I derived from small-angle scattering data: implications for regulation.

A novel approach for enhancing the catalytic efficiency of a protease at low temperature: reduction in substrate inhibition by chemical modification

A novel structure of an antikinase and its inhibitor

A picornaviral loop-to-loop replication complex.

Activation of Myosin Light Chain Kinase Requires Translocation of Bound Calmodulin

Activation of the retroviral budding factor ALIX.

An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis

Archiving of Integrative Structural Models

Assignment of segments of the bacteriorhodopsin sequence to positions in the structural map.

Binding of N-Terminus Fragments of Cardiac Myosin-Binding C-protein to Actin

Book reviews

C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change

C-terminal domain of KipI from Bacillus subtilis

COAGULATION FACTOR, NMR, 15 STRUCTURES

COAGULATION FACTOR, NMR, 20 STRUCTURES

Ca2+-induced structural changes in phosphorylase kinase detected by small-angle X-ray scattering

Calmodulin Binding to Myosin Light Chain Kinase Begins at Substoichiometric Ca2+Concentrations: A Small-Angle Scattering Study of Binding and Conformational Transitions†

Calmodulin Remains Extended upon Binding to Smooth Muscle Caldesmon: A Combined Small-Angle Scattering and Fourier Transform Infrared Spectroscopy Study†

Calmodulin binds a highly extended HIV-1 MA protein that refolds upon its release.

Calmodulin disrupts the structure of the HIV-1 MA protein

Cardiac myosin-binding protein C decorates F-actin: implications for cardiac function.

Changes in small-angle X-ray scattering parameters observed upon binding of ligand to rabbit muscle pyruvate kinase are not correlated with allosteric transitions

Characterization of the solution structure of a neuroligin/beta-neurexin complex

Clinically Linked Mutations in the Central Domains of Cardiac Myosin-Binding Protein C with Distinct Phenotypes Show Differential Structural Effects

Coassembling Peptide-Based Biomaterials: Effects of Pairing Equal and Unequal Chain Length Oligopeptides

Conformational analysis of PKI(5-22)amide, the active inhibitory fragment of the inhibitor protein of the cyclic AMP-dependent protein kinase

Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions

Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase

Contrast Variation

Corrigendum to “A picornaviral loop-to-loop replication complex” [J. Struct. Biol. 166 (2009) 251–262]

Corrigendum to “Calmodulin Disrupts the Structure of the HIV-1 MA Protein” [J. Mol. Biol. 400/4 (2010) 702–714]

Crystal structure of TTHA0988 in space group P43212

Denatured states of ribonuclease A have compact dimensions and residual secondary structure

Development of experimental techniques to study protein and nucleic acid structures

Differences in the heme environment of soybean leghemoglobin components shown by 1H-NMR spectroscopy

Differential effects of substrate on type I and type II PKA holoenzyme dissociation

Domain organization of the monomeric form of the Tom70 mitochondrial import receptor

Dynamic Light Scattering

Editorial overview --New frontiers of biophysical methods: Tools for structural biology and beyond

Effect of temperature during assembly on the structure and mechanical properties of peptide-based materials

Effects of chain length on oligopeptide hydrogelation

Effects of gadolinium chelate on the evolution of the nanoscale structure in peptide hydrogels

Effects of macromolecular crowding on an intrinsically disordered protein characterized by small-angle neutron scattering with contrast matching

Erratum to “Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor” [J. Mol. Biol. 388 (2009) 1043–1058]

Evolution of quaternary structure in a homotetrameric enzyme

Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures

Fractal dimension of an intrinsically disordered protein: small-angle X-ray scattering and computational study of the bacteriophage λ N protein

Further insights into calmodulin-myosin light chain kinase interaction from solution scattering and shape restoration

Global Conformational Changes Control the Reactivity of Methane Monooxygenase†

HIV-1 Reverse Transcriptase Monomers Adopt Multiple Conformations in Solution

Histidine kinase regulation by a cyclophilin-like inhibitor

Human Cardiac Myosin Binding Protein C: Structural Flexibility within an Extended Modular Architecture

Inelastic neutron scattering in biology

Inelastic neutron scattering in biology

Insights into biomolecular function from small-angle scattering.

Invited review: probing the structures of muscle regulatory proteins using small-angle solution scattering.

K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity

LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States

Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein

Ligand-induced conformational changes via flexible linkers in the amino-terminal region of the inositol 1,4,5-trisphosphate receptor.

Light Scattering

Low-angle Scattering of Neutrons and X-rays

MULCh: modules for the analysis of small-angle neutron contrast variation data from biomolecular assemblies

Mechanisms associated with cGMP binding and activation of cGMP-dependent protein kinase

Molecular basis for proton-dependent anion binding by soybean leghaemoglobin a

Mutation in a flexible linker modulates binding affinity for modular complexes

Myosin light chain kinase: functional domains and structural motifs

Naysaying the Neutron Scattering Society

Neutron Diffraction And Scattering

Neutron Diffraction Studies of Bacteriorhodopsin Structure

Neutron Resonance Scattering Shows Specific Binding of Plutonium to the Calcium-Binding Sites of the Protein Calmodulin and Yields Precise Distance Information

Neutron diffraction studies of bacteriorhodopsin