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List of works by Volker Haucke

5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors

scientific article

A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch.

scientific article published in November 2017

A Golgi-associated lipid kinase controls peripheral nerve myelination

scientific article published on 13 November 2020

A Model for Fast-Track Exocytosis of Synaptic Vesicles

A Presynaptic Perspective on Transport and Assembly Mechanisms for Synapse Formation

scientific article published on 14 October 2020

A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy

scientific article published on 16 May 2019

A dual role of SNAP-25 as carrier and guardian of synaptic transmission

scientific article

A grab to move on: ER-endosome contacts in membrane protrusion formation and neurite outgrowth

scientific article published on 9 April 2015

A lipid off-switch for mTORC1.

scientific article published on 2 August 2017

A matrix to build on

scientific article published on 01 January 2001

A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR

scientific article

A novel twist in membrane dePHormation

scientific article published in October 2014

A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis

scientific article

A phosphoinositide conversion mechanism for exit from endosomes

scientific article published on 13 January 2016

A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling.

scientific article published on 29 May 2014

A putative role for intramolecular regulatory mechanisms in the adaptor function of amphiphysin in endocytosis

scientific article

AP180 and CALM: Dedicated endocytic adaptors for the retrieval of synaptobrevin 2 at synapses

scientific article published on July 2011

ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma

scientific article

ATM-dependent cell-cycle arrest tamed in the test tube

scientific article published in December 2000

Adaptin' endosomes for synaptic vesicle recycling, learning and memory

scientific article

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling

scientific article

An exciting calcium sensor for smell

scientific article published in April 2011

Analysis of the sorting signals directing NADH-cytochrome b5 reductase to two locations within yeast mitochondria.

scientific article published on July 1997

Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding

scientific article published on 7 August 2008

Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells

scientific article published on 04 November 2019

At the crossroads of chemistry and cell biology: inhibiting membrane traffic by small molecules

scientific article

Autophagosome Formation by Endophilin Keeps Synapses in Shape

scientific article published in November 2016

Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module

scientific article published on 01 July 2018

BAR domain scaffolds in dynamin-mediated membrane fission

scientific article published on February 2014

Berlin Editorial

scientific article published on 12 May 2015

Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles

scientific article published in October 2013

CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process

scientific article

Calcium-Triggered Exocytosis and Clathrin-Mediated Endocytosis of Synaptic Vesicles

Cargo takes control of endocytosis

scientific article published in October 2006

Cell biology: Membrane kiss mediates hormone secretion

scientific article published on 15 June 2016

Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors

scientific article published on 09 January 2014

Clathrin-mediated endocytosis at synapses

scientific article

Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses.

scientific article

Clathrin/AP-2-dependent endocytosis: a novel playground for the pharmacological toolbox?

scientific article published on January 2008

Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth.

scientific article published on 9 December 2014

Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrity

scientific article

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

scientific journal article

Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2

scientific article published on 23 January 2013

Coupling of exocytosis and endocytosis at the presynaptic active zone

scientific article published on 5 December 2017

Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

scientific article published on 19 June 2013

Crystal structure of nucleotide-free dynamin

scientific article

Crystal structure of the dynamin tetramer

scientific article

Cycling of Synaptic Vesicles: How Far? How Fast!

Development of 1,8-naphthalimides as clathrin inhibitors

scientific article

Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins

scientific article published on 24 September 2015

Directing lipid transport at membrane contact sites

scientific article published in April 2016

Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing

scientific article

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

scientific article published on 22 April 2019

Dissecting the ins and outs of excitement: glutamate receptors on the move

article published in 2000

Dual interaction of synaptotagmin with mu2- and alpha-adaptin facilitates clathrin-coated pit nucleation

scientific article

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake

scientific article published on 13 March 2020

Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points.

scientific article published on 15 February 2017

Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis

scientific article published on 29 June 2020

Endocytosis in the adaptation to cellular stress

scientific article published on 18 August 2020

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

scientific article published on 09 March 2020

Faculty of 1000 evaluation for Integrin endosomal signalling suppresses anoikis

Faculty of 1000 evaluation for Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity

scholarly article published 27 August 2014

Fast neurotransmitter release regulated by the endocytic scaffold intersectin ⬇️

scientific article published on 30 April 2013

Functional assay of effectors of ADP ribosylation factor 6 during clathrin/AP-2 coat recruitment to membranes

scientific article published on January 2005

Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin

scientific article

Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis

scientific article (publication date: May 1999)

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

scientific article

Gadkin: A novel link between endosomal vesicles and microtubule tracks

scientific article published on July 2010

Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes

scientific article

Gottfried Schatz (1936-2015)-mitochondrial pioneer and ambassador for science

scientific article

Greasing the synaptic vesicle cycle by membrane lipids

scientific article published on 8 June 2013

Hopping Pits Catch Fusing Granules

scientific article published in October 2015

How synapsin I may cluster synaptic vesicles

scientific article published on June 2011

Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating

scientific article

Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking

scholarly article

Identifying Small-Molecule Inhibitors of the Clathrin Terminal Domain

scientific article published on 01 January 2018

Imaging of doxorubicin release from theranostic macromolecular prodrugs via fluorescence resonance energy transfer

scientific article published on 28 August 2014

Import and folding of proteins by mitochondria

scientific article published on January 1995

Import of proteins into mitochondria and chloroplasts

scientific article published in March 1997

Incomplete arrest in the outer membrane sorts NADH-cytochrome b5 reductase to two different submitochondrial compartments

scientific article

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

scientific article published on 17 January 2013

Inositol Triphosphate Signaling Triggers Lysosome Biogenesis Via Calcium Release from Endoplasmic Reticulum Stores

scientific article published in 2022

Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites

scientific article published in 2021

Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus

scientific article

Intersectin 1: a versatile actor in the synaptic vesicle cycle

scientific article published on February 2010

Intersectin associates with synapsin and regulates its nanoscale localization and function

scientific article published on 23 October 2017

Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission

scientific article published on 01 January 2020

Liberating sleeping beauties by cutting the hook

scientific article published on 01 November 2000

Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

scientific article published on 19 June 2017

Lipids and lipid modifications in the regulation of membrane traffic

scientific article published on 24 July 2007

Lipids, GTPases, and their regulators in membrane dynamics: an intracellular ménage à trois

scientific article published in March 2015

Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles

scientific article published on 11 May 2016

Lysosomal localization of GLUT8 in the testis--the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction.

scientific article

Mas37p, a novel receptor subunit for protein import into mitochondria.

scientific article published on April 1995

Mechanical signals regulate TORC2 activity

scientific article published on 01 September 2018

Membrane Biology: Fission behind BARs ⬇️

scientific article published on June 5, 2012

Membrane remodeling in clathrin-mediated endocytosis

scientific article published on 03 September 2018

Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamily

scientific article published on 17 July 2011

Modes and mechanisms of synaptic vesicle recycling

scientific article published on 23 March 2016

Molecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2

scientific article

Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation

scientific article

Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2

scientific journal article

Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2.

scholarly article

Molecular mechanisms of presynaptic membrane retrieval and synaptic vesicle reformation

scientific article

Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.

scientific article published in June 2019

Multi-colour direct STORM with red emitting carbocyanines

scientific article

Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain

scientific article published on 8 September 2015

Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain

article

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

scientific article published on 06 September 2018

Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction

scientific article published on 29 April 2019

Nanoscale coupling of endocytic pit growth and stability

scientific article published on 27 November 2019

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

scientific article published on 28 October 2020

Neurotransmission: spontaneous and evoked release filing for divorce

scientific article

Oligomerization of dynamin superfamily proteins in health and disease

scientific article published on January 2013

On the endocytosis rollercoaster

scientific article published in Nature

Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles

scientific article published on 26 May 2015

PERKing up the ER stress response

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation

scientific article published on 10 December 2021

PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

scientific article

PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling

scientific article published on 24 October 2013

PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules

scientific article published on 4 April 2018

Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis

scientific article published on 9 April 2015

Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway

scientific article published on 12 December 2019

Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly

scientific article published on 12 October 2023

Phosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.

scientific article published on 17 February 2016

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

scientific article published on 25 October 2017

Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch

scientific article

Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.

scientific article

Phospho-dependent binding of the clathrin AP2 adaptor complex to GABAA receptors regulates the efficacy of inhibitory synaptic transmission

scientific journal article

Phosphoinositide conversion in endocytosis and the endolysosomal system

scientific article published on 27 December 2017

Phosphoinositide switches in endocytosis and in the endolysosomal system

scientific article published on 28 April 2019

Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signalling

scientific article published on March 2007

Phosphoinositides in endocytosis

scientific article published on 28 September 2014

Phosphoinositides in the control of lysosome function and homeostasis

scientific article published on 05 August 2019

Phosphoinositides: regulators of membrane traffic and protein function

scientific article published on 12 February 2007

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

scientific article

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

scientific article published on 30 August 2018

Presynaptic endocytic factors in autophagy and neurodegeneration.

scientific article published on 6 January 2018

Probing heterobivalent binding to the endocytic AP-2 adaptor complex by DNA-based spatial screening.

scientific article

Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1

scientific article published on 26 August 2019

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

scientific article published on 09 February 2011

Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression

scientific article published on 01 January 2019

Quantitative proteomics analysis of detergent-resistant membranes from chemical synapses: evidence for cholesterol as spatial organizer of synaptic vesicle cycling

scientific article published on 21 July 2006

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.

scientific article published on 26 September 2016

Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth

scientific article published on 05 June 2020

Ramping up the autophagy-lysosome system to cope with osmotic stress

scientific article published on 20 July 2020

Recognition of a basic AP-2 binding motif within the C2B domain of synaptotagmin is dependent on multimerization

scientific article

Recognition of the tryptophan-based endocytosis signal in the neonatal Fc Receptor by the mu subunit of adaptor protein-2.

scientific article

Reconstitution of the protein insertion machinery of the mitochondrial inner membrane ⬇️

scientific article published on August 1, 1997

Recycling endosomes in neuronal membrane traffic

scientific article published in June 2007

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

scientific article published on 19 June 2017

Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex

scientific article

Regulation of inhibitory synaptic transmission by a conserved atypical interaction of GABA(A) receptor beta- and gamma-subunits with the clathrin AP2 adaptor

scientific article published on 10 July 2008

Regulation of phosphoinositide-metabolizing enzymes by clathrin coat proteins

scientific article published in January 2012

Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor  2 subunit

scientific article

Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2

scientific article

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

scientific article

Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes

scientific article

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

scientific article

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

scientific article

Shaping membranes for endocytosis.

scientific article published on January 2011

Shuttling receptors for peroxisomes

scientific article published on 01 June 2001

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway

scientific article

Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity

scientific article published on 12 December 2016

SnapShot: endocytic trafficking

scientific article published in April 2009

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

scientific journal article

Specific interaction between SNAREs and epsin N-terminal homology (ENTH) domains of epsin-related proteins in trans-Golgi network to endosome transport

scientific article

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses

scientific article published on 23 December 2019

Spontaneous neurotransmission: a SNARE for the rest

scientific article published in January 2012

Stabilization of GABA(A) receptors at endocytic zones is mediated by an AP2 binding motif within the GABA(A) receptor β3 subunit.

scientific article published in February 2012

Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes

scientific article

Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization and recycling

scientific article published on February 2006

Stonins--specialized adaptors for synaptic vesicle recycling and beyond?

scientific article published on January 2010

Structural insights into dynamin-mediated membrane fission

scientific article published on October 2012

Structure and function of membrane-integral receptors

Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity

scientific article

Super-Resolution Imaging of Tight and Adherens Junctions: Challenges and Open Questions

scientific article published on 23 January 2020

Surface functionalization of silica nanoparticles supports colloidal stability in physiological media and facilitates internalization in cells

scientific article published on 7 May 2012

Synapsin I senses membrane curvature by an amphipathic lipid packing sensor motif.

scientific article

Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly.

scientific article

Synaptic requiem: a duet for Piccolo and Bassoon

scientific article published on 8 March 2013

Synthesis of the Pitstop family of clathrin inhibitors

Tamoxifen therapy in a murine model of myotubular myopathy

scientific article published in Nature Communications

The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple Negative Breast Cancer

scientific article published on 08 June 2020

The Molecular Mechanisms Mediating Class II PI 3-Kinase Function in Cell Physiology

scientific article published on 02 January 2021

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

scientific article

The Yeast Mitochondrial Protein Import Receptor Mas20p Binds Precursor Proteins through Electrostatic Interaction with the Positively Charged Presequence

scientific article published in Journal of Biological Chemistry

The axonal endo-lysosomal and autophagic systems

scientific article published on 28 December 2020

The cell adhesion protein CAR is a negative regulator of synaptic transmission

article

The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit

scientific article

The early steps of endocytosis: from cargo selection to membrane deformation

scientific article published on 31 March 2011

The first steps of protein import into mitochondria

scientific article published on February 1997

The neural cell adhesion molecule promotes maturation of the presynaptic endocytotic machinery by switching synaptic vesicle recycling from adaptor protein 3 (AP-3)- to AP-2-dependent mechanisms.

scientific article published in October 2013

The oncogenic TBC domain protein USP6/TRE17 regulates cell migration and cytokinesis

scientific article

The progressive ankylosis protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface

scientific article published on 27 July 2016

The tortoise and the hare revisited

scientific article published on 3 September 2013

Trafficking and signalling at the synapse: where are we heading to?

scientific article published on 01 June 2007

TrkAing signals with clathrin

scientific article published on 01 April 2002

Turning CALM into excitement: AP180 and CALM in endocytosis and disease

scientific article published on 31 May 2012

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells

scientific article published on 11 April 2016

Tyrosine phosphorylation regulates the endocytosis and surface expression of GluN3A-containing NMDA receptors

scientific article published on February 2013

Tyrosine-based endocytic motifs stimulate oligomerization of AP-2 adaptor complexes

scientific article

Vacuoles fuse with V0

scientific article published on 01 April 2001

Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation

scientific article published on 01 February 2020

Vesicle budding: a coat for the COPs

scientific article

Vesicle uncoating regulated by SH3-SH3 domain-mediated complex formation between endophilin and intersectin at synapses

scientific article published on 17 December 2014

Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission

scientific journal article

Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes

scientific article published on 13 February 2020

Where Proteins and Lipids Meet

scientific article published on 01 February 2003

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

scientific article

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