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Authors whose works are in public domain in at least one jurisdiction

List of works by Marylyn D. Ritchie

1-50 of 360 results

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions

scientific article published in February 2003

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

scientific article

The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies

scientific article (publication date: 26 January 2011)

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

scientific article

Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity

scientific article

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

scientific article (publication date: October 2013)

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Methods of integrating data to uncover genotype-phenotype interactions

scientific article

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

scientific article published on 5 June 2008

Genetic determinants of response to warfarin during initial anticoagulation

scientific article

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record

scientific article

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies

scientific article

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

scientific article

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

scientific article published in February 2006

Renin-angiotensin system gene polymorphisms and atrial fibrillation

scientific article

Quality control procedures for genome-wide association studies

scientific article published in 2011

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

scientific article

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

scientific article published on December 2016

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus

scientific article

The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study

scientific article

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

scientific article published on 05 March 2013

Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems

scientific article

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

scientific article published on 02 March 2016

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science

scientific article

Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping

scientific article published on 27 June 2012

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

scientific article published on 24 May 2017

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study

scientific article

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

scientific article

Genetic identification of familial hypercholesterolemia within a single U.S. health care system

scientific article published on December 2016

Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study

scientific article

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network

scientific article published on 30 October 2011

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes

scientific article published on 18 November 2011

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

scientific article published on 11 January 2016

A novel method to identify gene-gene effects in nuclear families: the MDR-PDT.

scientific article

The phenotypic legacy of admixture between modern humans and Neandertals

scientific article

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

scientific article published on 12 September 2013

Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies.

scientific article

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

scientific article published on December 2012

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

scientific article

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records

scientific article published on January 2016

Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records

scientific article

Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases

scientific article

Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum.

scientific article published on September 1993