List of works - Christoph Dehio

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum.

scientific article published on 12 January 2018

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

scientific article

A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening

scientific article published on 26 June 2019

A bacterial conjugation machinery recruited for pathogenesis

scientific article

A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella.

scientific article published on 26 October 2017

A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells

scientific article

A translocated bacterial protein protects vascular endothelial cells from apoptosis

scientific article

A translocated effector required for Bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors

scientific article (publication date: June 2014)

A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome

scientific article published on 27 February 2009

A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative type IV secretion system

scientific article published on 30 August 2013

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins

scientific article

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

scientific article published on 19 August 2015

An engineered heparin-binding form of VEGF-E (hbVEGF-E). Biological effects in vitro and mobilizatiion of precursor cells

scientific article published in January 2003

An experimental strategy for the identification of AMPylation targets from complex protein samples

scientific article published on 20 March 2014

An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics.

scientific article published on 15 November 2017

Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1.

scientific article published on November 2015

BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures

scientific article

Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production

scientific article

Bacterial persistence within erythrocytes: a unique pathogenic strategy of Bartonella spp.

scientific article

Bacterial type IV secretion systems in human disease

scientific article published on 08 June 2009

Bartonella alsatica sp. nov., a new Bartonella species isolated from the blood of wild rabbits

scientific article

Bartonella and Brucella--weapons and strategies for stealth attack

scientific article published on August 2013

Bartonella as emerging pathogens The 1st International Conference on Bartonella as Emerging Pathogens, organized by C. Dehio and A. Sander, was held at the Max-Planck-Institute, TÃ¼bingen, Germany, 5â 7 March 1999

article

Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.).

scientific article

Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane

scientific article published on 28 January 2021

Bartonella entry mechanisms into mammalian host cells

scientific article published on 16 May 2012

Bartonella gene transfer agent: Evolution, function, and proposed role in host adaptation

scientific article published on 09 July 2019

Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake

scientific article

Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system

scientific article

Bartonella henselae: subversion of vascular endothelial cell functions by translocated bacterial effector proteins

scientific article published on 25 October 2008

Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats.

scientific article

Bartonella-host-cell interactions and vascular tumour formation

scientific article

Biological Diversity and Molecular Plasticity of FIC Domain Proteins.

scientific article

CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes ⬇️

scientific article published on June 16, 1997

Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells.

scientific article published on June 2000

Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii

article

Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector

scientific article published on January 2003

Characterization of the genome composition of Bartonella koehlerae by microarray comparative genomic hybridization profiling

scientific article published in September 2005

Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution

scientific article published on 21 September 2010

Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells

scientific article published on 22 October 2010

Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae.

scientific article

Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold

scientific article

Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion

scientific article published in March 2004

Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin

scientific article

Definitions and guidelines for research on antibiotic persistence

scientific article published on 01 July 2019

Differential Opa specificities for CD66 receptors influence tissue interactions and cellular response to Neisseria gonorrhoeae

article

Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome

scientific article published on 22 July 2013

Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation

scientific article published on 12 March 2009

Dual input control: activation of the Bartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system

scientific article published on 4 October 2013

Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors.

scientific article published on 14 March 2009

Editorial overview: Bacterial systems biology

scientific article published on 01 October 2017

Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

scientific article published on 21 October 2015

Evolutionary Diversification of Host-Targeted Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

scientific article published on 31 July 2021

Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

scientific article published on 07 March 2017

Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results

scientific article published on 14 February 2017

Fic domain-catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA

scientific article

Functional dissection of the conjugative coupling protein TrwB.

scientific article published on 2 April 2010

Functional interactions between type IV secretion systems involved in DNA transfer and virulence

scientific article published on 01 November 2005

Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen

scientific article

Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation

scientific article published on 19 May 2015

Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori

scientific article

Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors

scientific article

Genomics of Host-Restricted Pathogens of the Genus Bartonella

article

Host cell interactome of tyrosine-phosphorylated bacterial proteins

scientific article published in April 2009

Host cell invasion by pathogenic Neisseriae.

scientific article

Imaging InlC secretion to investigate cellular infection by the bacterial pathogen Listeria monocytogenes

scientific article published on 19 September 2013

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects.

scientific article published in July 2018

Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction

scientific article published on 30 July 2008

Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome ⬇️

scientific article published on September 1, 1997

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

scientific article published on 19 January 2016

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp ⬇️

scientific article published on January 1, 2012

Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella

scientific article

Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis

scientific article

Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells: a model for cellular invasion by Neisseria gonorrhoeae.

scientific article published on August 1998

Maintenance of broad-host-range incompatibility group P and group Q plasmids and transposition of Tn5 in Bartonella henselae following conjugal plasmid transfer from Escherichia coli.

scientific article published on January 1997

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

scientific article

Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria.

scientific article published on 26 March 2018

Molecular and cellular basis of bartonella pathogenesis

scientific article published in January 2004

Multi-omic measurements of heterogeneity in HeLa cells across laboratories

scientific article published on 18 February 2019

Multi-scale Gaussian representation and outline-learning based cell image segmentation

scientific article

NEMix: single-cell nested effects models for probabilistic pathway stimulation

scientific article

New insights into the role of Bartonella effector proteins in pathogenesis

scientific article

New perspectives into bacterial DNA transfer to human cells

scientific article published on 29 June 2012

Opa binding to cellular CD66 receptors mediates the transcellular traversal of Neisseria gonorrhoeae across polarized T84 epithelial cell monolayers.

scientific article

Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella

scientific article (publication date: 2011)

Parapoxviruses: potential alternative vectors for directing the immune response in permissive and non-permissive hosts.

scientific article

Partial disruption of translational and posttranslational machinery reshapes growth rates of Bartonella birtlesii

scientific article

Persistence ofBartonellaspp. stealth pathogens: from subclinical infections to vasoproliferative tumor formation ⬇️

scientific article published on 07 February 2012

Persistent intracellular pathogens ⬇️

scientific article published on March 19, 2012

Phenotype and hormonal status of transgenic tobacco plants overexpressing the rolA gene of Agrobacterium rhizogenes T-DNA

scientific article published on 01 December 1993

Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism

scientific article published on 28 January 2014

Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae

scientific article

Publisher Correction: Definitions and guidelines for research on antibiotic persistence

scientific article published on 01 July 2019

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

scientific article published on 07 March 2019

Recent progress in understanding Bartonella-induced vascular proliferation

scientific article

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

scientific article

Role of distinct type-IV-secretion systems and secreted effector sets in host adaptation by pathogenic Bartonella species

scientific article published on 06 February 2019

Signature-tagged mutagenesis: technical advances in a negative selection method for virulence gene identification

scientific article

Simultaneous analysis of large-scale RNAi screens for pathogen entry

scientific article

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

scientific article

Splicing of the rolA transcript of Agrobacterium rhizogenes in Arabidopsis

scientific article

Stable expression of a single-copy rolA gene in transgenic Arabidopsis thaliana plants allows an exhaustive mutagenic analysis of the transgene-associated phenotype

scientific article published on November 1993

Structure and biological activity of the short-chain lipopolysaccharide from Bartonella henselae ATCC 49882T.

scientific article

Structure of the N-terminal Gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis

scientific article (publication date: 2014)

Survival mechanisms of VEGF and PlGF during microvascular remodeling

scientific article

Syndecan-1 and syndecan-4 can mediate the invasion of OpaHSPG-expressing Neisseria gonorrhoeae into epithelial cells

scientific article published on 01 February 2000

Systems-level analysis of host-pathogen interaction using RNA interference

scientific article published on 05 February 2013

Systems-level interference strategies to decipher host factors involved in bacterial pathogen interaction: from RNAi to CRISPRi

scientific article published on 28 August 2017

The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook

scientific article

The Bartonella henselae VirB/Bep system interferes with vascular endothelial growth factor (VEGF) signalling in human vascular endothelial cells.

scientific article

The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection

scientific article

The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome

scientific article published on 14 April 2017

The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes

scientific article

The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells

scientific article published on April 2004

The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection

scientific article published in November 2002

The early nodulin gene SrEnod2 from Sesbania rostrata is inducible by cytokinin

scientific article published on January 1, 1992

The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells

scientific article

Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells

scientific article published on 9 September 2011

Type IV Effector Secretion and Subversion of Host Functions by Bartonella and Brucella Species.

scientific article

VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells.

scientific article published in August 2005

Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts

scientific article published on 01 March 2002

Versatility of the BID Domain: Conserved Function as Type-IV-Secretion-Signal and Secondarily Evolved Effector Functions Within Bartonella-Infected Host Cells

scientific article published on 03 May 2019

Virulence-associated type IV secretion systems of Bartonella

scientific article

gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

scientific article published on 7 October 2015

List of works by Christoph Dehio

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum.

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening

A bacterial conjugation machinery recruited for pathogenesis

A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella.

A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells

A translocated bacterial protein protects vascular endothelial cells from apoptosis

A translocated effector required for Bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors

A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome

A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative type IV secretion system

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

An engineered heparin-binding form of VEGF-E (hbVEGF-E). Biological effects in vitro and mobilizatiion of precursor cells

An experimental strategy for the identification of AMPylation targets from complex protein samples

An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics.

Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1.

BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures

Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production

Bacterial persistence within erythrocytes: a unique pathogenic strategy of Bartonella spp.

Bacterial type IV secretion systems in human disease

Bartonella alsatica sp. nov., a new Bartonella species isolated from the blood of wild rabbits

Bartonella and Brucella--weapons and strategies for stealth attack

Bartonella as emerging pathogens The 1st International Conference on Bartonella as Emerging Pathogens, organized by C. Dehio and A. Sander, was held at the Max-Planck-Institute, TÃ¼bingen, Germany, 5â 7 March 1999

Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.).

Bartonella effector protein C mediates actin stress fiber formation via recruitment of GEF-H1 to the plasma membrane

Bartonella entry mechanisms into mammalian host cells

Bartonella gene transfer agent: Evolution, function, and proposed role in host adaptation

Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake

Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system

Bartonella henselae: subversion of vascular endothelial cell functions by translocated bacterial effector proteins

Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats.

Bartonella-host-cell interactions and vascular tumour formation

Biological Diversity and Molecular Plasticity of FIC Domain Proteins.

CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes ⬇️

Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells.

Characterization of Genes Involved in Long-Term Bacteremia in Mice by Bartonella birtlesii

Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector

Characterization of the genome composition of Bartonella koehlerae by microarray comparative genomic hybridization profiling

Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution

Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells

Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae.

Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold

Coordinated activation of VEGFR-1 and VEGFR-2 is a potent arteriogenic stimulus leading to enhancement of regional perfusion

Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin

Definitions and guidelines for research on antibiotic persistence

Differential Opa specificities for CD66 receptors influence tissue interactions and cellular response to Neisseria gonorrhoeae

Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome

Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation

Dual input control: activation of the Bartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system

Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors.

Editorial overview: Bacterial systems biology

Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

Evolutionary Diversification of Host-Targeted Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results

Fic domain-catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA

Functional dissection of the conjugative coupling protein TrwB.

Functional interactions between type IV secretion systems involved in DNA transfer and virulence

Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen

Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation

Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori

Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors

Genomics of Host-Restricted Pathogens of the Genus Bartonella

Host cell interactome of tyrosine-phosphorylated bacterial proteins

Host cell invasion by pathogenic Neisseriae.

Imaging InlC secretion to investigate cellular infection by the bacterial pathogen Listeria monocytogenes

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects.

Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction

Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome ⬇️

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp ⬇️

Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella

Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis

Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells: a model for cellular invasion by Neisseria gonorrhoeae.

Maintenance of broad-host-range incompatibility group P and group Q plasmids and transposition of Tn5 in Bartonella henselae following conjugal plasmid transfer from Escherichia coli.

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria.

Molecular and cellular basis of bartonella pathogenesis

Multi-omic measurements of heterogeneity in HeLa cells across laboratories