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List of works by Patrik Rorsman

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A pancreatic islet-specific microRNA regulates insulin secretion

scientific article
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

scientific article
Electrophysiology of the pancreatic beta-cell

scientific article (publication date: 1989)
Diabetes mellitus and the β cell: the last ten years

scientific article published on March 2012
miR-375 maintains normal pancreatic alpha- and beta-cell mass

scientific article
Insulin granule dynamics in pancreatic beta cells

scientific article
Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells

scientific article
Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

scientific article
Calcium and delayed potassium currents in mouse pancreatic beta-cells under voltage-clamp conditions

scientific article published in May 1986
Regulation of insulin secretion in human pancreatic islets

scientific article published on 04 September 2012
Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels

scientific article
Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion

scientific article
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice

scientific article
The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

scientific article
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells

scientific article published in Nature
Glucose dependent K+-channels in pancreatic beta-cells are regulated by intracellular ATP.

scientific article
Glucose-sensing mechanisms in pancreatic beta-cells.

scientific article
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis

scientific article
Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

scientific article
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

scientific article
Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells

scientific article published on April 2004
Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

scientific article published on 01 July 1997
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

scientific article
Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

scientific article
SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells

scientific article
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis

scientific article published in June 2010
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

scientific article published on April 1998
The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

scientific article published on May 1997
The Cell Physiology of Biphasic Insulin Secretion.

scientific article published in April 2000
Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets

scientific article published in December 1999
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

scientific article published in June 2007
Stimulus-secretion coupling in pancreatic beta cells.

scientific article published on January 1994
Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels

scientific article published in November 2000
Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells

scientific article published on January 1995
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels

scientific article
K(ATP) channels and islet hormone secretion: new insights and controversies

scientific article
MicroRNA-7a regulates pancreatic β cell function

scientific article
Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells

scientific article published in September 2000
Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

scientific article
Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells

scientific article published on January 2002
Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels

scientific article published on September 1997
Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic beta-cells

scientific article published in February 1990
Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans

scientific article published on 13 February 2004
Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells

scientific article
Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes

scientific article published on 01 March 1998
Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells

scientific article
Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice

scientific journal article
Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes

scientific article published on December 2013
Novel aspects of the molecular mechanisms controlling insulin secretion

scientific article published on 29 May 2008
Regulation of calcium in pancreatic α- and β-cells in health and disease

scientific article published on 15 December 2011

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