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List of works by Andreas Radbruch

1,25-dihydroxyvitamin D(3) promotes IL-10 production in human B cells

scientific article published in August 2008

1,25-dihydroxyvitamin D3 impairs NF-κB activation in human naïve B cells

scientific article published on 21 March 2011

12th Joint Meeting of the Signal Transduction Society (STS). Signal Transduction: Receptors, Mediators and Genes Weimar, Germany. 29-31 October 2008. Abstracts

article

25-hydroxvitamin D3 promotes the long-term effect of specific immunotherapy in a murine allergy model

scientific article published on 20 June 2014

9-cis retinoic acid and 1.25-dihydroxyvitamin D3 drive differentiation into IgA+ secreting plasmablasts in human naïve B cells

scientific article published on 27 October 2020

9-cis retinoic acid modulates the type I allergic immune response

scientific article published on 16 May 2017

A Ca(2+) concentration of 1.5 mM, as present in IMDM but not in RPMI, is critical for maximal response of Th cells to PMA/ionomycin

scientific article

A GATA-3 binding site in the first intron of the interleukin-4 gene defines a critical element for the memory expression of interleukin-4 in Th lymphocytes

A critical control element for interleukin-4 memory expression in T helper lymphocytes

scientific article

A long-term perspective on immunity to COVID

scholarly article

A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines ⬇️

scientific article published on October 1, 1979

A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow.

scientific article published on 8 January 2015

Aberrant activation of B cells in patients with rheumatoid arthritis

scientific article

Abstracts of the 10th Congress of the European Association of NeuroOncology. Marseille, France. September 6-9, 2012

scientific article published in September 2012

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95

scientific article published on 01 June 2008

Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells

scientific article published in August 2005

Adaptation of humoral memory

scientific article published on June 2006

Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model.

scientific article published on 30 December 2016

Advancing cytometry for immunology

scientific article published in December 2012

Allergic sensitization and allergen exposure during pregnancy favor the development of atopy in the neonate

scientific article published on 01 January 2001

Allergy for a lifetime?

scientific article published on March 2010

An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus

scientific article published on 29 August 2018

An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3.

scientific article

An interleukin 4-induced DNase I hypersensitive site indicates opening of the gamma 1 switch region prior to switch recombination

scientific article published in January 1989

Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix

scientific article (publication date: 14 March 1995)

Analysis of B-cell subpopulations in systemic lupus erythematosus.

scientific article published on 12 September 2003

Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

scientific article published on 20 June 2011

Analysis of the antigen-specific T cell response in reactive arthritis by flow cytometry

scientific article published on December 2000

Andreas Radbruch: winner of the Avery-Landsteiner Prize for Immunology 2014.

scientific article published in November 2014

Animal models in infection and inflammation - chance and necessity

scientific article published on 01 August 2009

Antibodies and B cell memory in viral immunity

scientific article published on September 2007

Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

scientific article

Antigen-driven PD-1+TOX+BHLHE40+ and PD-1+TOX+EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ

scientific article published on 09 December 2020

Antigen-specific cytometry

scientific article

Antigen-specific cytometry--new tools arrived!

scientific article published on May 2004

Approaching clinical proteomics: current state and future fields of application in cellular proteomics

scientific article published on October 2009

Approaching clinical proteomics: current state and future fields of application in fluid proteomics

scientific article

Are interferon-related biomarkers advantageous for monitoring disease activity in systemic lupus erythematosus? A longitudinal benchmark study

scientific article published in September 2017

Authentic IgM Fc Receptor (FcμR).

scientific article published on 13 July 2017

Autoantibodies from long-lived 'memory' plasma cells of NZB/W mice drive immune complex nephritis

scientific article

Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts

scientific article published on 11 March 2014

Autologous stem-cell transplantation in refractory autoimmune diseases after in vivo immunoablation and ex vivo depletion of mononuclear cells

scientific article

Autoregulation of Th1-mediated inflammation by twist1.

scientific article published on 28 July 2008

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow

scientific article published on 2 February 2016

B-cell-directed therapies for autoimmune disease

scientific article published on 07 July 2009

Bad memories: understanding and removal of pathogenic consequences of immunological memory in inflammatory rheumatic diseases. The IMPAM consortium

scientific article published in August 2012

Blood dendritic cells in systemic lupus erythematosus exhibit altered activation state and chemokine receptor function

scientific article published on 22 October 2009

Blood-borne human plasma cells in steady state are derived from mucosal immune responses

scientific article

Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: implications for the treatment of autoimmunity.

scientific article published on 20 June 2012

Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice

scientific article published on 7 August 2015

CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function.

scientific article published on 08 March 2004

CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations

scientific article published on 12 March 2004

CD40L expression by CD4+ but not CD8+ T cells regulates antiviral immune responses in acute LCMV infection in mice.

scientific article published on 26 August 2016

CD45RA-expressing memory/effector Th cells committed to production of interferon-γ lack expression of CD31 ⬇️

scientific article published on 01 June 1997

CD49b-dependent establishment of T helper cell memory.

scientific article published on 30 July 2013

CD49b/CD69-Dependent Generation of Resting T Helper Cell Memory.

scientific article published on 10 July 2013

CD69+ memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue-resident memory T lymphocytes

scientific article published on 30 January 2019

CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch.

scientific article published on 24 April 2010

CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients

scientific article published on January 2009

CXCR4-CXCL12 interaction is important for plasma cell homing and survival in NZB/W mice

scientific article published on 10 February 2018

Cell population identification using fluorescence-minus-one controls with a one-class classifying algorithm

scientific article published on 27 August 2014

Cell therapy for autoimmune diseases: does it have a future?

scientific article published in November 2004

Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

scientific article

Characterization of kidney infiltrating T cells in the NZB/W F1 lupus model.

scientific article published on 24 February 2004

Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response

scientific article published in August 2002

Chromosomal localisation of the CD4cre transgene in B6·Cg-Tg(Cd4-cre)1Cwi mice

scientific article

Cis- and trans-acting gene regulation is associated with osteoarthritis

scientific article

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

scientific article published on June 1986

Class switching and consecutive loss of dsDNA-reactive B1a B cells from the peritoneal cavity during murine lupus development

scientific article published in June 2010

Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4 ⬇️

scientific article published on September 15, 1998

Competence and competition: the challenge of becoming a long-lived plasma cell

scientific article published on 15 September 2006

Control of immunoglobulin class switch recombination

scientific article published on February 1986

Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus

scientific article published in May 2003

Corrigendum: Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.

scientific article published in December 2016

Corrigendum: Multispectral Flow Cytometry: The Consequences of Increased Light Collection

scientific article published on 14 May 2019

Cyto 2011 - overview of the XXVI ISAC Congress Proceedings Issue of Cytometry

scientific article published on 01 May 2011

Cytokine imprinting - mechanisms for memory

scientific article published on 16 September 2011

Cytokine memory of T helper lymphocytes

scientific article

Cytometric analyses in systemic autoimmune diseases

scientific article published in August 2002

Cytometry for immunology: A stable and happy marriage ⬇️

scientific article published on August 1, 2013

Cytometry for immunology: The marriage continues

scientific article published on 20 December 2013

Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells

scientific article published in 2022

Deep Phenotyping of CD11c+ B Cells in Systemic Autoimmunity and Controls

Deep phenotypical characterization of human CD3+ CD56+ T cells by mass cytometry

scientific article published on 24 November 2020

Defining TNF-α- and LPS-induced gene signatures in monocytes to unravel the complexity of peripheral blood transcriptomes in health and disease

scientific article

Deletion of Cmu genes in mouse B lymphocytes upon stimulation with LPS ⬇️

scientific article published on January 1, 1983

Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant ⬇️

scientific article published on November 1, 1984

Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells.

scientific article published on 4 March 2015

Demethylation of the constant region genes of immunoglobulins reflects the differentiation state of the B cell

scientific article published on September 1992

Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells

scientific article published on 4 July 2011

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

scientific article

Detection and characterization of plasma cells in peripheral blood: correlation of IgE+ plasma cell frequency with IgE serum titre

scientific article published on 01 December 2002

Detection and isolation of cytokine secreting cells using the cytometric cytokine secretion assay

scientific article published on 01 February 2002

Determination of background, signal-to-noise, and dynamic range of a flow cytometer: A novel practical method for instrument characterization and standardization.

scientific article published on 27 September 2017

Development and resolution of secondary autoimmunity after autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: competition of plasma cells for survival niches?

scientific article published on 29 January 2013

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

scientific article published on 7 February 2010

Differences between Human and Mouse IgM Fc Receptor (FcµR)

scientific article published in 2021

Differential Expression of miR-4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF).

scientific article published on 16 September 2016

Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls

scientific article published on 02 August 2007

Differential expression of a conserved new mRNA in lymphoid cells.

scientific article

Differential expression of miR-4520a is associated with gain of function mutations in Familial Mediterranean Fever (FMF).

scientific article

Differential regulation of P-selectin ligand expression in naive versus memory CD4+ T cells: evidence for epigenetic regulation of involved glycosyltransferase genes

scientific article

Differential regulation of the expression of chemokine receptor 3 and 4 during plasma cell differentiation.

scientific article published on 24 February 2004

Differential surrogate light chain expression governs B-cell differentiation

scientific article

Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.

scientific article

Direct assessment of thymic reactivation after autologous stem cell transplantation

scientific article published on 22 February 2008

Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes

scientific article published on 14 July 2015

Directed Ig class switch recombination in activated murine B cells.

scientific article published on June 1987

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

scientific article published on 22 May 2020

Distinct antigen presenting cell-derived signals induce TH cell proliferation and expression of effector cytokines

scientific article published in January 1992

Diversity of clonal T cell proliferation is mediated by differential expression of CD152 (CTLA-4) on the cell surface of activated individual T lymphocytes.

scientific article published in October 2003

Does gene expression analysis inform us in rheumatoid arthritis?

scientific article

Drug induced modulation of T cell activation and differentiation in atopic dermatitis patients.

scientific article published on 26 February 2009

Editorial

Effects of reduced ATP-formation on cytokine production and proliferation in human peripheral CD4T cells

Efficient tetanus toxoid immunization on vitamin D supplementation

scientific article published on 12 January 2011

Endogenous Calcitriol Synthesis Controls the Humoral IgE Response in Mice

scientific article published on 6 November 2017

Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location

scientific article published on 01 January 2019

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

scientific article published on November 2016

Establishment of juvenile and tolerant immune systems in patients with autoimmune diseases treated with immunoablation and autologous stem cell therapy

Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation

scientific article

Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry

scientific article

Evolution of the six horse IGHG genes and corresponding immunoglobulin gamma heavy chains

scientific article published on 4 July 2002

Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease

scientific article

Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.

scientific article published on January 2003

Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3.

scientific article published in March 2007

Expression of a 4-(hydroxy-3-nitro-phenyl) acetyl (NP) specific equi-murine IgE antibody that mediates histamine release in vitro and a type I skin reaction in vivo

scientific article published on November 2002

Expression profiling in synovitis: ranking of candidates, diagnostic performance and individualized interpretation

scientific article published on 17 February 2005

Extensive hemispheric diffusion restriction in haemolytic uremic syndrome.

scientific article

Fair play at EJI ⬇️

scientific article published on January 1, 2013

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells

scientific article published on May 1994

Fluorescence-activated cytometry cell sorting based on immunological recognition

scientific article

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

scientific article

Fracture healing is accelerated in the absence of the adaptive immune system.

scientific article

Frequency of immunoglobulin E class switching is autonomously determined and independent of prior switching to other classes

scientific article published on June 1994

From cellular pathology to cell therapy

scientific article published in February 2015

From transcriptome to cytome: integrating cytometric profiling, multivariate cluster, and prediction analyses for a phenotypical classification of inflammatory diseases

scientific article

Functional Roles of the IgM Fc Receptor in the Immune System

scientific article published on 03 May 2019

GATA-3 in human T cell helper type 2 development

scientific article

GATA-3 in human T helper cell type 2 development

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

scientific article

Gene expression in chronically activated Th cells

Gene expression in inflammatory rheumatic diseases

scientific article published in September 2007

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response

scientific article published on 26 October 2004

Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming

scientific article

German Rheumatism Research Center in Berlin : A Leibniz institute

scientific article published on 30 June 2016

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

HLA-B27-restricted antigen presentation by human chondrocytes to CD8+ T cells: potential contribution to local immunopathologic processes in ankylosing spondylitis

scientific article

HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus.

scientific article published in January 2010

High gradient magnetic cell separation with MACS

scholarly article by Stefan Miltenyi et al published 1990 in Cytometry

High-resolution microbiota flow cytometry reveals dynamic colitis-associated changes in fecal bacterial composition

scientific article

Homeostasis and Durability of T-Cell Memory-The Resting and the Restless T-Cell Memory

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus

scientific article

How to cope with pathogenic long-lived plasma cells in autoimmune diseases

scientific article published on December 2008

Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production

scientific article published in June 2008

Human IgA-Expressing Bone Marrow Plasma Cells Characteristically Upregulate Programmed Cell Death Protein-1 Upon B Cell Receptor Stimulation

scientific article published on 12 February 2021

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory

scientific article

Humoral immunity and long-lived plasma cells

scientific article

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

scientific article

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

scientific article published in November 2010

IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus

scientific article

IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes.

scientific article published in August 2007

IL-10-producing B cells are characterized by a specific methylation signature

scientific article published on 07 May 2019

IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells.

scientific article published in June 2014

IL-2 Expression in Activated Human Memory FOXP3(+) Cells Critically Depends on the Cellular Levels of FOXP3 as Well as of Four Transcription Factors of  T Cell Activation.

scientific article published on 27 August 2012

IRF4 - a factor for class switching and antibody secretion

scientific article published on 01 July 2006

ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap.

scientific article published on 27 July 2016

Identification and characterization of SmD183-119-reactive T cells that provide T cell help for pathogenic anti-double-stranded DNA antibodies

scientific article published on February 2003

Identification of Amino Acid Residues in Human IgM Fc Receptor (FcµR) Critical for IgM Binding

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells

scientific article published on 16 September 2016

Identification of T Cell-Mediated Vascular Rejection After Kidney Transplantation by the Combined Measurement of 5 Specific MicroRNAs in Blood

scientific article published on 24 August 2015

Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception

scientific article published on 22 May 2020

Identification of cross-reactive antibodies for the detection of lymphocytes, myeloid cells and haematopoietic precursors in the naked mole rat

scientific article published on 05 September 2019

Identification of immunodominant CD4+ T cell epitopes in patients with Yersinia-induced reactive arthritis by cytometric cytokine secretion assay

scientific article

Ig gene rearrangement and expression in the progeny of B-cell progenitors in the course of clonal expansion in bone marrow cultures

scientific article published on September 1987

Immunoglobulin V region variants in hybridoma cells. I. Isolation of a variant with altered idiotypic and antigen binding specificity

scientific article

Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes.

scientific article

Immunoglobulin class switching: in vitro induction and analysis

scientific article

Immunological memories of the bone marrow

scientific article published in May 2018

Immunological memory in rheumatic inflammation — a roadblock to tolerance induction

scholarly article

Immunological memory of the bone marrow

scientific article published in August 2015

Immunological memory stabilizing autoreactivity

scientific article

Immunological memory: lessons from the past and a look to the future

scientific article published in February 2016

Immunomagnetic cell sorting--pushing the limits

scientific article

Immunomagnetic enrichment of disseminated epithelial tumor cells from peripheral blood by MACS

scientific article published on March 1, 1998

Immunomodulation by vitamin D

scientific article published on 01 September 2018

Immunomodulation of high-dose vitamin D supplementation during allergen specific immunotherapy

scientific article published on 04 August 2020

Impact of cellular therapies on autoreactive, long-lived plasma cells in autoimmune diseases (AID)

Impact of in utero Th2 immunity on T cell deviation and subsequent immediate-type hypersensitivity in the neonate

scientific article published on 01 February 2000

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients

scholarly article

In vivo preactivated autoreactive Th cells in healthy individuals.

scientific article published on 26 January 2001

Individual T helper cells have a quantitative cytokine memory

scientific article

Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells

scientific article published on April 1994

Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge

scientific article published in October 2009

Inexpensive upgrading of a FACS I and isolation of rare somatic variants by double-fluorescence sorting

scientific article

Influence of both TCR repertoire and severity of the atopic status on the cytokine secretion profile of Parietaria officinalis-specific T cells

scientific article published on 01 January 1998

Inhibition of calcineurin-NFAT signaling by the pyrazolopyrimidine compound NCI3.

scientific article published in September 2007

Innate-like effector differentiation of human invariant NKT cells driven by IL-7.

scientific article published in April 2008

Insights into the control of immunoglobulin class switch recombination from analysis of targeted mice ⬇️

scientific article published on September 1, 1997

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions

scientific article published on 14 January 2010

Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.

scientific article published on 31 August 2017

Intravenous injection of a D1 protein of the Smith proteins postpones murine lupus and induces type 1 regulatory T cells

scientific article published in November 2004

Introduction to the topic: Stem cells and cell therapy

scientific article published in May 2009

Is long-term humoral immunity in the mucosa provided by long-lived plasma cells? A question still open

scientific article published in May 2006

Isolation and characterization of CD34+ hematopoietic stem cells from human peripheral blood by high‐gradient magnetic cell sorting ⬇️

scientific article published on 01 January 1993

Isolation and characterization of allergen-binding cells from normal and allergic donors ⬇️

scientific article published on 01 August 1995

Isolation and characterization of anti-monosialoganglioside monoclonal antibody 19-9 class-switch variants

scientific article published on December 1985

Isolation of Human B Cell Populations

Isolation of immunoglobulin class-switch and variable-region variants from mouse myeloma and hybridoma cell lines

scientific article published on 01 January 1982

Isolation of myeloma variants with predefined variant surface immunoglobulin by cell sorting ⬇️

scientific article published on August 1, 1978

Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class

scientific article

Isolation of viable Hodgkin and Reed-Sternberg cells from Hodgkin disease tissues

scientific article

Joachim R. Kalden (1937–2021)

scholarly article

Keeping up with the stress of antibody production: BAFF and APRIL maintain memory plasma cells

scholarly article

Lifetime of plasma cells in the bone marrow

scientific article published in July 1997

Long term immune reconstitution after immunoablation and autologous CD34 cell therapy in autoimmune diseases.

scientific article published on 4 February 2002

Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

scientific article published on February 2011

Long-lived plasma cells and their contribution to autoimmunity

scientific article

Long-lived plasma cells are early and constantly generated in New Zealand Black/New Zealand White F1 mice and their therapeutic depletion requires a combined targeting of autoreactive plasma cells and their precursors

scientific article published on 2 March 2015

Long-lived plasma cells in immunity and immunopathology

scientific article published on 21 October 2005

Long-lived plasma cells in immunity and inflammation.

scientific article

Long-lived plasma cells survive independent of antigen

scientific article

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

scientific article

Long-term follow-up of fertility and pregnancy in autoimmune diseases after autologous haematopoietic stem cell transplantation

scientific article published on 13 August 2016

Long-term immune reconstitution after autologous stem-cell transplantation for severe autoimmune diseases. ⬇️

scientific article published on 17 February 2005

Long-term immune reconstitution in patients treated with autologous stem cell transplantation for refractory autoimmune diseases.

scientific article published on 24 February 2004

Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-γ memory in human CD4(+) T lymphocytes.

scientific article published in March 2013

Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism

scientific article published on January 2001

Low secretion of tumor necrosis factor alpha, but no other Th1 or Th2 cytokines, by peripheral blood mononuclear cells correlates with chronicity in reactive arthritis

scientific article published on 01 October 1999

Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis.

scientific article published on 29 April 2009

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

scientific article published on 31 August 2015

Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs

scientific article published on 11 January 2012

MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines

scientific article

Macrophages in bone fracture healing: Their essential role in endochondral ossification

scientific article published on 31 October 2015

Magnetofluorescent liposomes for increased sensitivity of immunofluorescence

scientific article published on 01 August 1995

Maintenance of CD8(+) memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation.

scientific article published on 16 August 2017

Maintenance of quiescent immune memory in the bone marrow

scholarly article

Maintenance of serum antibody levels

scientific article

Mapping urinary chemokines in human lupus nephritis: Potentially redundant pathways recruit CD4+ and CD8+ T cells and macrophages

scientific article published on 18 October 2016

Measurement of proliferative responses of cultured lymphocytes

scientific article

Membrane glucocorticoid receptor expression on peripheral blood mononuclear cells in patients with ankylosing spondylitis.

scientific article published in September 2006

Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis

scientific article published in January 2004

Membrane glucocorticoid receptors (mGCR) on monocytes are up-regulated after vaccination

scientific article published on 18 December 2006

Membrane glucocorticoid receptors are down regulated by glucocorticoids in patients with systemic lupus erythematosus and use a caveolin-1-independent expression pathway

scientific article published on 31 January 2006

Memory B and memory plasma cells

scientific article published on September 2010

Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription

scientific article

Memory on the move

scientific article

MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes

scientific article published on 06 December 2018

Monoclonal anti-equine IgE antibodies with specificity for different epitopes on the immunoglobulin heavy chain of native IgE

scientific article published on 01 March 2003

Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint

scientific article

Monocyte-specific gene signatures in rheumatoid arthritis

scholarly article by A Grützkau et al published 24 February 2004 in Arthritis Research and Therapy

Multispectral flow cytometry: The consequences of increased light collection

scientific article published on 13 June 2016

Nerve growth factor and neurotrophin-3 mediate survival of pulmonary plasma cells during the allergic airway inflammation

scientific article published in April 2009

Neuroradiological Response Criteria for High-grade Gliomas ⬇️

scientific article published on June 17, 2011

New insights into the function of bone marrow

scientific article published on 24 April 2018

Nibrin functions in Ig class-switch recombination

scientific journal article

Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow.

scientific article

Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys

scientific article published on 24 June 2020

Nuclear factor of activated T cells regulates the expression of interleukin-4 in Th2 cells in an all-or-none fashion

scientific article published on 17 July 2014

Organ culture of human lymphoid tissue. II. Marked differences in cytokine production and proliferation between slice and suspension cultures of human spleen ⬇️

scientific article published on July 14, 1997

Organization and maintenance of immunological memory by stroma niches

scientific article published on August 2009

Organization of immunological memory by bone marrow stroma

scientific article published on 15 February 2010

Organization of the equine immunoglobulin constant heavy chain genes. I. c epsilon and c alpha genes

scientific article

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

scientific article published in Nature

P1. Immunoablation with t cell depleted autologous peripheral blood stem cell rescue produces complete remission in thrombocytopenic purpura (TTP) recidivant and refractory to standard treatment

PRI: Re-Analysis of a Public Mass Cytometry Dataset Reveals Patterns of Effective Tumor Treatments

scientific article published on 03 May 2022

Pathogenesis of systemic lupus erythematosus

scientific article published in April 2015

Pathogenic memory plasma cells in autoimmunity

scientific article published on 30 October 2019

Pathophysiological hypoxia affects the redox state and IL-2 signalling of human CD4+ T cells and concomitantly impairs survival and proliferation

scientific article published on 17 May 2013

Persistence of effector memory Th1 cells is regulated by Hopx

scientific article published on 27 October 2010

Persistence of plasma cells in the kidneys of autoimmune NZB/W mice.

scientific article published on 26 January 2001

Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies

scientific article

Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus

scientific article published on September 2003

Phenotypic analysis of B-cells and plasma cells.

scientific article published in January 2007

Physiological and Pathophysiological Roles of IgM Fc Receptor (FcµR) Isoforms

scholarly article

Plasma cell differentiation and survival

scientific article published on April 2008

Plasma cell differentiation in T-independent type 2 immune responses is independent of CD11c(high) dendritic cells

scientific article published on November 2006

Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals

scientific article published in August 2003

Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression

scientific article published on February 2004

Plasma cells as an innovative target in autoimmune disease with renal manifestations

scientific article published on 29 February 2016

Plasma cells for a lifetime?

scientific article

Plasma-cell like morphotype with loss of CD3 expression by Th1 cytokine producing cells.

scientific article published on 24 February 2003

Predominant cellular immune response to the cartilage autoantigenic G1 aggrecan in ankylosing spondylitis and rheumatoid arthritis

scientific article published on 28 February 2003

Prenatal sensitization in a mouse model

scientific article published on 01 September 2000

Presentation of the Center of Competence in Berlin

scientific article published in August 2002

Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.

scientific article

Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors

scientific article published on 30 July 2018

Protective and pathogenic memory plasma cells.

scientific article

Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch and TcR recombination

scientific article published on October 1990

Protective role of interferon gamma in murine antigen-induced arthritis.

scientific article published on 13 September 2004

Rapid Isolation of Functional Human Skin Tissue-Resident Memory T Lymphocytes

scientific article

Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE.

scientific article published on 21 January 2015

Reactivation of rheumatoid arthritis after pregnancy: increased phagocyte and recurring lymphocyte gene activity

scientific article published on 01 October 2008

Recombination between antibody heavy chain variable-region genes: evidence for gene conversion

scientific article published on August 1983

Recruitment of Histone Methyltransferase Ehmt1 to Foxp3 TSDR Counteracts Differentiation of Induced Regulatory T Cells

scientific article published on 27 July 2019

Regulation and function of T1/ST2 expression on CD4+ T cells: induction of type 2 cytokine production by T1/ST2 cross-linking

scientific article published on 01 March 2001

Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells

scientific article published in February 2005

Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation

scientific article published on 05 September 2019

Regulation of T helper cell cytokine expression: functional dichotomy of antigen-presenting cells

scientific article published in January 1993

Regulatory T cells in experimental arthritis.

scientific article published on 12 September 2003

Research consortium Neuroimmunology and pain in the research network musculoskeletal diseases

scientific article published on 13 April 2018

Resetting the immune system with immunoablation and autologous haematopoietic stem cell transplantation in autoimmune diseases

scientific article

Resident memory CD4<sup>+</sup> T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction

scientific article published in 2022

Response to Parks et al.: Multispectral Flow Cytometry: Unaddressed Issues and Recommendations for Improvement

scientific article published on 14 August 2020

Response to methotrexate in early rheumatoid arthritis is associated with a decrease of T cell derived tumour necrosis factor alpha, increase of interleukin 10, and predicted by the initial concentration of interleukin 4.

scientific article published on April 2000

Response to: Comments on the publication "Determination of Background, Signal-to-Noise, and Dynamic Range of a Flow Cytometer: A Novel Practical Method for Instrument Characterization and Standardization" by Giesecke et al

scientific article published on 29 January 2020

Response: Commentary: Memory CD8(+) T Cells Colocalize with IL-7(+) Stromal Cells in Bone Marrow and Rest in Terms of Proliferation and Transcription

scientific article published on 31 August 2016

Rethinking ‘immunological memory’: Local and systemic immunity provided by bone marrow‐resident memory cells

scholarly article

Rimexolone inhibits proliferation, cytokine expression and signal transduction of human CD4+ T-cells

scientific article published on 2 April 2010

Role of Blimp-1 in programing Th effector cells into IL-10 producers

scientific article published on 29 July 2014

Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura

scientific article

SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself

scientific article

SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren's syndrome

scientific article published on 30 December 2016

SIICA‐DGfI 2011 Joint Meeting: Front‐line immunology with sensorial stimulations, neuromuscular activity and phago/pinocytosis ⬇️

scientific article published on 29 December 2011

Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation

scientific article

Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG+ plasma cell persistence in the bone marrow

scientific article published on 25 March 2019

Selecting B cells and plasma cells to memory

scientific article published on February 2005

Selection and depletion of plasma cells based on the specificity of the secreted antibody

scientific article published on 2 November 2014

Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies

scientific article published on 12 November 2019

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo

scientific article published on 25 November 2017

Sensitive analysis of recombination activity using integrated cell surface reporter substrates

scientific article published on November 1999

Sensitive visualization of peptide presentation in vitro and ex vivo.

scientific article published in July 2003

Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.

scientific article published on 30 April 2009

Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.

scientific article published in May 1998

Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

scientific article

Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

article published in 2004

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

scientific article published on April 2010

Shutdown of class switch recombination by deletion of a switch region control element.

scientific article

SiPaGene: A new repository for instant online retrieval, sharing and meta-analyses of GeneChip expression data

scientific article

Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus

scientific article published on 01 April 2008

Siglec-1-positive plasmacytoid dendritic cells (pDCs) in human peripheral blood: A semi-mature and myeloid-like subset imbalanced during protective and autoimmune responses

scientific article published on 7 December 2015

Signals controlling rest and reactivation of T helper memory lymphocytes in bone marrow ⬇️

scientific article published on March 30, 2012

Simultaneous Presence of Non- and Highly Mutated Keyhole Limpet Hemocyanin (KLH)-Specific Plasmablasts Early after Primary KLH Immunization Suggests Cross-Reactive Memory B Cell Activation

scientific article published on 07 May 2018

Simultaneous cytometric analysis of (auto)antigen-reactive T and B cell proliferation

scientific article published on 01 December 2002

Single-cell transcriptomes of murine bone marrow stromal cells reveal niche-associated heterogeneity

scientific article published on 07 June 2019

Small but mighty: how the MACS-technology based on nanosized superparamagnetic particles has helped to analyze the immune system within the last 20 years

scientific article published on July 2010

Specialist network "Inflammatory-rheumatic systemic diseases." Developmental perspectives for rheumatology in Germany

scientific article published in February 2001

Specific expression of surface interferon-gamma on interferon-gamma producing T cells from mouse and man

scientific article published on 01 January 1996

Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer's patches in mice

scientific article published on 17 February 2020

Spontaneous immunoglobulin class switching in myeloma and hybridoma cell lines differs from physiological class switching

scientific article published on January 1982

Stable IL-2 decision making by endogenous c-Fos amounts in peripheral memory T-helper cells.

scientific article published on 3 April 2012

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment

scientific article published in January 2000

Static and dynamic components synergize to form a stable survival niche for bone marrow plasma cells

scientific article published on 30 May 2014

Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab

scientific article published on 9 September 2010

Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells

scientific article published on 01 August 2020

Stromal niches, plasma cell differentiation and survival.

scientific article

Substitution in position 3 of cyclosporin A abolishes the cyclophilin-mediated gain-of-function mechanism but not immunosuppression.

scientific article published on 28 October 2003

Survival of long-lived plasma cells is independent of antigen

scientific article published in November 1998

Switch from NP-specific IgG3 to IgG1 in the mouse hybridoma cell line S24/63/63

scientific article published on 01 March 1982

Synovial and peripheral blood CD4+FoxP3+ T cells in spondyloarthritis

scientific article published on 15 September 2011

Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation

scientific article published on 13 May 2020

Systemic T‐cell unresponsiveness during rush bee‐venom immunotherapy ⬇️

scientific article published on 01 March 1998

Systemic inflammatory rheumatic diseases competence network

scientific article published in April 2004

Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development

scientific article published on May 2017

T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion.

scientific article published on 8 April 2014

T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.

scientific article published on 17 February 2016

T-cell epitope mapping by flow cytometry ⬇️

scientific article published on August 1, 1998

T-cell receptor transgenic models of inflammatory disorders: relevance for atopic dermatitis?

scientific article

T1/ST2 expression is enhanced on CD4+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo.

scientific article published in April 1999

T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function

scientific article

Takayasu arteritis is characterised by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab

scientific article published on 27 September 2011

Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus

scientific article published on 01 September 2020

Targeting pathogenic T helper cell memory

scientific article published on March 2011

Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response

scientific article published in December 2010

Th memory for interleukin-17 expression is stable in vivo

scientific article published in October 2008

The Maintenance of Memory Plasma Cells

The challenge: understanding the molecular pathogenesis of osteoarthritis and developing innovative therapeutic concepts

scientific article published in May 2014

The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta

scientific article

The intestinal microbiota determines the colitis-inducing potential of T-bet-deficient Th cells in mice.

scientific article published on 6 September 2017

The intracellular 52-kd Ro/SSA autoantigen in keratinocytes is up-regulated by tumor necrosis factor alpha via tumor necrosis factor receptor I

scientific article published on 01 February 2005

The lifestyle of memory CD8(+) T cells

scientific article published on 21 March 2016

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

scientific article published on 10 October 2010

The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.

scientific article published on 19 May 2012

The pro- and anti-inflammatory potential of IL-12: the dual role of Th1 cells

scientific article published in September 2007

The pro- and anti-inflammatory potential of interleukin-12.

scientific article published in August 2007

The pro-inflammatory immunological memory : twist1 as a marker for chronically activated T lymphocytes

scientific article published in December 2008

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

scientific article

The role of Nfil3 in zebrafish hematopoiesis

scientific article published on 2 May 2012

The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells

scientific article

The role of the miR-148/-152 family in physiology and disease.

scientific article

The systemic and SmD183-119-autoantigen-specific cytokine memory of Th cells in SLE patients

scientific article published on 31 July 2006

Therapeutic inhibition of proteasomes in systemic lupus erythematosus

scientific article published on 23 November 2011

Thymus-Derived Regulatory T Cells Are Positively Selected on Natural Self-Antigen through Cognate Interactions of High Functional Avidity.

scientific article published on May 2016

Transcription factor co-occupied regions in the murine genome constitute T-helper-cell subtype-specific enhancers.

scientific article

Transcriptional control networks of cell differentiation: insights from helper T lymphocytes

scientific article

Treatment of spondyloarthropathies with antibodies against tumour necrosis factor alpha: first clinical and laboratory experiences

scientific article

Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood

scientific article published on March 2002

Type 1 regulatory T cells in treatment of murine lupus.

scientific article published on 17 February 2005

Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options

scientific article published on 29 March 2017

Type II membrane protein CD69 regulates the formation of resting T-helper memory

scientific article published on 2 April 2012

Unbiased transcriptomes of resting human CD4⁺ CD45RO⁺ T lymphocytes

scientific article

Unraveling complexity of rheumatoid synovial gene expression by comparison with purified leukocyte profiles.

scientific article published on 24 February 2004

Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells

scientific article

Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice

scientific article published in May 2003

Vitamin D receptor activation improves allergen-triggered eczema in mice

scientific article published on 22 September 2011

Vitamin D receptor binds to the ε germline gene promoter and exhibits transrepressive activity

scientific article published on November 2010

Welcome aboard!

scientific article published on 01 March 2014

Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells

scientific article published in July 2010

Wild immunology assessed by multidimensional mass cytometry.

scientific article published on 12 July 2016

[Autologous hematopoietic stem cell transplantation for autoimmune diseases : Current indications and mode of action, a review on behalf of the EBMT Autoimmune Diseases Working Party (ADWP)]

scientific article published on 30 April 2020

[Experimental rheumatology--on the way to a fundamental understanding of rheumatic diseases]

scientific article published on 01 September 2005

[Living rheumatology]

scientific article published on 01 February 2007

[News from the German Society of Rheumatology]

scientific article published on 01 December 2004

[Preface]

scientific article published on 01 January 2002

[The what, the how and the why in rheumatological research]

scientific article published on 01 December 2020

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

scientific article published on 22 January 2015

miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2.

scientific article

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