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List of works by Leann Tilley

A new Python library to analyse skeleton images confirms malaria parasite remodelling of the red blood cell membrane skeleton

scientific article published on 15 February 2018

A phosphatidylcholine-BODIPY 581/591 conjugate allows mapping of oxidative stress in P. falciparum-infected erythrocytes.

scientific article published in May 2009

An Australian network to support the understanding and control of parasites

scientific article published on 30 January 2006

An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes

scientific article

Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.

scientific article

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

scientific article published in Nature Communications

Band 3 mobility in camelid elliptocytes: implications for erythrocyte shape

scientific article published on 01 July 1993

Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

scientific article published on 10 December 2014

Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP).

Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites

scientific article published in 2022

Characterization of a series of far-red-absorbing thiobarbituric acid oxonol derivatives as fluorescent probes for biological applications ⬇️

scientific article published on June 1, 2003

Characterization of the pathway for transport of the cytoadherence-mediating protein, PfEMP1, to the host cell surface in malaria parasite-infected erythrocytes.

scientific article published in November 2003

Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence

scientific article published on 17 February 2016

Correction: Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage

scientific article published in PLoS ONE

Cryo transmission X-ray imaging of the malaria parasite, P. falciparum.

scientific article

Decreased rotational diffusion of band 3 in melanesian ovalocytes from Papua, New Guinea ⬇️

scientific article published on April 1, 1991

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

scientific article

Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking

scientific article published on 18 July 2019

Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains

scientific article

Detailed morphological characterisation of Hendra virus infection of different cell types using super-resolution and conventional imaging.

scientific article

Detection and quantification of early-stage malaria parasites in laboratory infected erythrocytes by attenuated total reflectance infrared spectroscopy and multivariate analysis

scientific article

Determination of protein subcellular localization in apicomplexan parasites

scientific article published on 17 September 2012

Diagnosing malaria infected cells at the single cell level using focal plane array Fourier transform infrared imaging spectroscopy.

scientific article

Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network.

scientific article published in April 2009

Fresnel coherent diffractive imaging tomography of whole cells in capillaries

Genetic ablation of a Maurer's cleft protein prevents assembly of the Plasmodium falciparum virulence complex.

scientific article published on 7 July 2011

Green fluorescent antibodies: novel in vitro tools

scientific article published on 01 June 2000

Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

scientific article published on 16 December 2015

High-resolution X-ray imaging of Plasmodium falciparum-infected red blood cells

scientific article published in October 2008

Histidine-rich protein 2 of the malaria parasite, Plasmodium falciparum, is involved in detoxification of the by-products of haemoglobin degradation.

scientific article published in June 2001

Human erythrocyte band 7.2b is preferentially labeled by a photoreactive phospholipid

scientific article published on 01 July 1996

Improving the quality of electron tomography image volumes using pre-reconstruction filtering

scientific article

Inhibition of phenylephrine-stimulated gluconeogenesis by chlorpromazine is mediated by alpha-adrenergic receptors

scientific article published on 01 April 1981

Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection.

scientific article

Iron and heme metabolism in Plasmodium falciparum and the mechanism of action of artemisinins

scientific article published on 07 August 2013

Local regularization of tilt projections reduces artifacts in electron tomography

scientific article published on 14 March 2014

MAHRP-1, a novel Plasmodium falciparum histidine-rich protein, binds ferriprotoporphyrin IX and localizes to the Maurer's clefts

scientific article (publication date: 12 September 2003)

MAHRP2, an exported protein of Plasmodium falciparum, is an essential component of Maurer's cleft tethers

scientific article (publication date: September 2010)

Malaria parasite proteins that remodel the host erythrocyte

scientific article published on May 2009

Modulation of the function of human MDR1 P-glycoprotein by the antimalarial drug mefloquine.

scientific article published on November 1996

Multimodal analysis of Plasmodium knowlesi-infected erythrocytes reveals large invaginations, swelling of the host cell, and rheological defects

scientific article published on 11 February 2019

Non-canonical metabolic pathways in the malaria parasite detected by isotope-tracing metabolomics.

scientific article

Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation.

scientific article published on August 1996

Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity

scientific article published on 26 July 2013

Novel endoperoxide antimalarials: synthesis, heme binding, and antimalarial activity.

scientific article published on March 2004

Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin.

scientific article published on March 2002

Optimal assay design for determining the in vitro sensitivity of ring stage Plasmodium falciparum to artemisinins.

scientific article

Organization and function of an actin cytoskeleton in Plasmodium falciparum gametocytes

scientific article published on 31 October 2014

Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

scientific article published on February 2004

Parasite-Mediated Degradation of Synthetic Ozonide Antimalarials Impacts In Vitro Antimalarial Activity

scientific article published on 20 December 2017

Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.

scientific article

Plasmodium falciparum metabolic pathways (MPMP) project upgraded with a database of subcellular locations of gene products

scientific article published on 12 April 2011

Plasmodium species: master renovators of their host cells

scientific article

Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum.

scientific article

Prospects for the treatment of drug-resistant malaria parasites.

scientific article published on June 2006

Protein trafficking in Plasmodium falciparum-infected red blood cells.

scientific article

Proteolytic digestion of band 3 at an external site alters the erythrocyte membrane organisation and may facilitate malarial invasion

scientific article published on 01 December 1993

Purification and kinetic characterisation of human erythrocyte actin.

scientific article published on October 1984

Quinoline antimalarials: mechanisms of action and resistance.

scientific article

Random sequence libraries displayed on phage: identification of biologically important molecules.

scientific article

Re-assessing the locations of components of the classical vesicle-mediated trafficking machinery in transfected Plasmodium falciparum

scientific article (publication date: August 2007)

Red blood cells polarize green laser light revealing hemoglobin's enhanced non-fundamental Raman modes

scientific article

Resonance Raman spectroscopy can detect structural changes in haemozoin (malaria pigment) following incubation with chloroquine in infected erythrocytes.

scientific article published on 4 March 2008

Selective permeabilization of the host cell membrane of Plasmodium falciparum-infected red blood cells with streptolysin O and equinatoxin II

scientific article published on April 2007

Serum lipoproteins promote efficient presentation of the malaria virulence protein PfEMP1 at the erythrocyte surface

scientific article

Shape-shifting gametocytes: how and why does P. falciparum go banana-shaped?

scientific article published on 30 August 2012

Signal-mediated export of proteins from the malaria parasite to the host erythrocyte.

scientific article

Solubilization of native actin monomers from human erythrocyte membranes

scientific article published on 01 January 1986

Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum

scientific article published on 14 March 2013

Specific inhibition of the eubacterial DNA ligase by arylamino compounds.

scientific article

Structural organisation of band 3 in Melanesian ovalocytes

scientific article published on 01 March 1993

Structure- and function-based design of Plasmodium-selective proteasome inhibitors

scientific article published on February 2016

Surface area-to-volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels

scientific article published on 27 September 2020

Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites.

scientific article published on April 2004

Synthesis and activity of some antimalarial bisquinolines.

scientific article published on January 1995

Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines.

scientific article published on August 2001

Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome

scientific article published on 7 November 2018

Targeted mutagenesis of the ring-exported protein-1 of Plasmodium falciparum disrupts the architecture of Maurer's cleft organelles.

scientific article published on 28 June 2008

The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes

scientific article published on 11 April 2008

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum

scientific article published on 10 December 2019

The Plasmodium falciparum protein RESA interacts with the erythrocyte cytoskeleton and modifies erythrocyte thermal stability.

scientific article

The Plasmodium falciparum-infected red blood cell

scientific article published in June 2011

The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum.

scientific article published on September 1997

The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma

scientific article

The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly

scientific article published on 09 May 2019

The metabolic repair enzyme phospho-glycolate phosphatase regulates central carbon metabolism and fosmidomycin sensitivity in Plasmodium falciparum

The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites

scientific article published on 01 May 2000

The quinoline-based drug, N-[4-[1-hydroxy-2-(dibutylamino)ethyl] quinolin-8-yl]-4-azidosalicylamide, photoaffinity labels the multidrug resistance protein (MRP) at a biologically relevant site

scientific article published on 01 December 1997

The ring-infected erythrocyte surface antigen of Plasmodium falciparum associates with spectrin in the erythrocyte membrane.

scientific article published in May 1991

The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis

scientific article published on 05 August 2019

The use of n-(9-anthroyloxy) fatty acids to determine fluidity and polarity gradients in phospholipid bilayers

scientific article published on 01 December 1979

Tip-enhanced Raman scattering (TERS) from hemozoin crystals within a sectioned erythrocyte

scientific article published on 12 April 2011

Tracking Glideosome-associated protein 50 reveals the development and organization of the inner membrane complex of Plasmodium falciparum.

scientific article

Ultrastructure of the asexual blood stages of Plasmodium falciparum.

scientific article

Whole cell imaging reveals novel modular features of the exomembrane system of the malaria parasite, Plasmodium falciparum

scientific article published on 18 September 2009

Whole-cell phase contrast imaging at the nanoscale using Fresnel coherent diffractive imaging tomography.

scientific article

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