List of works by Gideon Davies

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

scientific article published on 13 July 2017

A 1-acetamido derivative of 6-epi-valienamine: an inhibitor of a diverse group of beta-N-acetylglucosaminidases

scientific article

A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan-Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus

scientific article published on 19 January 2019

A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors

scientific article

A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase

scientific article published on 24 February 2020

A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites

scientific article published on 01 September 2019

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

scientific article published on 22 September 2017

A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides

scientific article published on 01 January 2007

A baculoviral system for the production of human β-glucocerebrosidase enables atomic resolution analysis

scientific article published on 29 May 2020

A census of carbohydrate-active enzymes in the genome of Arabidopsis thaliana.

scientific article

A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

scientific article

A complex gene locus enables xyloglucan utilization in the model saprophyte Cellvibrio japonicus

scientific article

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes

scientific article

A master of its sulfate

scientific article published on 01 August 2004

A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi

scientific article

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

scientific article

A second-generation ferrocene-iminosugar hybrid with improved fucosidase binding properties

scientific article published on 09 February 2016

A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism

scientific article published on 8 November 2016

Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules

scientific article

Activity, stability and 3-D structure of the Cu(ii) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens

scientific article

Activity-based probes for functional interrogation of retaining β-glucuronidases

scientific article

Activity-based protein profiling reveals dynamic substrate-specific cellulase secretion by saprotrophic basidiomycetes

scientific article published on 17 January 2022

An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 β-Glycosidase fromThermotoga maritima

article

An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion.

scientific article published on 22 February 2018

An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-α-mannanase inhibitor

scientific article

An evolving hierarchical family classification for glycosyltransferases

scientific article (publication date: 25 April 2003)

Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise

scientific article

Analysis of the reaction coordinate of alpha-L-fucosidases: a combined structural and quantum mechanical approach

scientific article

Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human -GlcNAcase

article

Anatomy of Glycosynthesis

Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A.

scientific article

Bacterial β-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2).

scientific article published on 26 April 2016

Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif.

scientific article published on 24 April 2018

Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates

scientific article

Building custom polysaccharides in vitro with an efficient, broad-specificity xyloglucan glycosynthase and a fucosyltransferase

scientific article published on 27 June 2011

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.

scientific article published on 2 May 2017

Carbohydrate anomalies in the PDB.

scientific article

Carbohydrate structure: the rocky road to automation

scientific article

Carbohydrate-active enzymes: sequences, shapes, contortions and cells

scientific article published on February 2016

Casuarine-6-O-alpha-D-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases

scientific article

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

scientific article

Cellulosome assembly revealed by the crystal structure of the cohesin-dockerin complex

scientific article

Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold

scientific article

Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants

scientific article

Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12

scientific article

Characterization of Escherichia coli OtsA, a trehalose-6-phosphate synthase from glycosyltransferase family 20.

scientific article published on 24 January 2002

Characterization of a novel pectate lyase, Pel10A, fromPseudomonas cellulosa

scientific article published on 23 July 2001

Chemistry's prodigal child: enzyme mechanism

Chemoenzymatic synthesis of 6-phospho-cyclophellitol as a novel probe of 6-phospho-β-glucosidases

scientific article

Chitinase inhibition by chitobiose and chitotriose thiazolines

scientific article

Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules

scientific article

Cloning, crystallization and preliminary X-ray analysis of a nucleotide-diphospho-sugar transferase spsA fromBacillus subtilis

scientific article published on 01 March 1999

Combinatorial assembly and design of enzymes

scientific article published on 13 January 2023

Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate

scientific article

Common Inhibition of Both β-Glucosidases and β-Mannosidases by Isofagomine Lactam Reflects Different Conformational Itineraries for Pyranoside Hydrolysis

scientific article published on 01 November 2004

Competitive and Covalent Inhibitors of Human Lysosomal Retaining Exoglucosidases

Complex pectin metabolism by gut bacteria reveals novel catalytic functions.

scientific article published on 22 March 2017

Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 α-Mannosidases

scientific article published on 27 December 2016

Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach

scientific article published on 11 May 2017

Conformational Behaviour of Azasugars Based on Mannuronic Acid

scientific article

Conformational analyses of the reaction coordinate of glycosidases

scientific article

Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases

scientific article

Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase

scientific article (publication date: 25 January 2017)

Convergent evolution sheds light on the anti-beta -elimination mechanism common to family 1 and 10 polysaccharide lyases

scientific article

Correction: Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluoro-oligosaccharide inhibitor of endo-xyloglucanases

scientific article published on 01 January 2019

Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism

scientific article published on 01 February 2016

Cracking the code, slowly: the state of carbohydrate-active enzymes in 2013

scientific article published on 26 September 2013

Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata

scientific article published on 19 February 2019

Crystal structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558

scientific article

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

scientific article

Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus

scientific article

Crystal structures of Clostridium thermocellum xyloglucanase, XGH74A, reveal the structural basis for xyloglucan recognition and degradation.

scientific article published on 13 June 2006

Crystallization and Preliminary X-ray Analysis of a Truncated Tissue Metalloproteinase Inhibitor Δ128-194 TIMP-2

scientific article published on 01 February 1993

Crystallization and preliminary X-ray analysis of a fungal endoglucanase I

scientific article published on 01 December 1992

Crystallization and preliminary X-ray analysis of nonglycosylated tissue inhibitor of metalloproteinases-1, N30QN78Q TIMP-1

scientific article published on 01 December 1993

Crystallization and preliminary X-ray analysis of the 6-phospho-α-glucosidase from Bacillus subtilis

article

Crystallization and preliminary X-ray analysis of the complex between a mouse Fab fragment and a single IgG-binding domain from streptococcal protein G

scientific article published on 01 October 1992

Crystallization and preliminary X-ray analysis of the laccase from Coprinus cinereus.

scientific article published in September 1997

Crystallization and preliminary X-ray crystallographic analysis of aTrichoderma reeseiβ-mannanase from glycoside hydrolase family 5

scientific article published on 01 May 1999

Crystallization of a DNA and N-acetylserine Binding Fragment (Residues 1 to 233) of Klebsiella aerogenes CysB Protein, a Member of the LysR Family

scientific article published on 01 January 1994

DNA-nogalamycin interactions: the crystal structure of d(TGATCA) complexed with nogalamycin

scientific article

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes

scientific article

Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding

scientific article

Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling

scientific article published on 12 December 2019

Discovery and characterization of a new family of lytic polysaccharide monooxygenases

scientific article

Discovery and characterization of a sulfoquinovose mutarotase using kinetic analysis at equilibrium by exchange spectroscopy.

scientific article published on 13 March 2018

Discovery of selective small-molecule activators of a bacterial glycoside hydrolase

scientific article

Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiont Teredinibacter turnerae

scientific article published on 30 September 2019

Dissecting conformational contributions to glycosidase catalysis and inhibition

scientific article published on 10 July 2014

Dissection of conformationally restricted inhibitors binding to a beta-glucosidase.

scientific article published in May 2006

Distortion of mannoimidazole supports a B2,5 boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens

scientific article published on 01 August 2019

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

scientific article

Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance

scientific article

Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases

scientific article

Erratum: Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

scientific article published in Nature

Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism

scientific article

Evidence for a dual binding mode of dockerin modules to cohesins

scientific article

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

scientific article

Exploiting the hydrophobic terrain in fucosidases with aryl-substituted pyrrolidine iminosugars

scientific article

Exploration of strategies for mechanism-based inhibitor design for family GH99 endo-α-1,2-mannanases.

scientific article published on 5 March 2018

Exploring the divalent effect in fucosidase inhibition with stereoisomeric pyrrolidine dimers.

scientific article published in May 2016

Family 6 Carbohydrate Binding Modules in β-Agarases Display Exquisite Selectivity for the Non-reducing Termini of Agarose Chains

scientific article published in Journal of Biological Chemistry

Formation of a Copper(II)-Tyrosyl Complex at the Active Site of Lytic Polysaccharide Monooxygenases Following Oxidation by H2O2

scientific article published on 12 November 2019

From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase

scientific article published on 14 November 2018

Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase

scientific article

Functional and informatics analysis enables glycosyltransferase activity prediction

scientific article published on 12 November 2018

Functional and structural characterization of a potent GH74 endo-xyloglucanase from the soil saprophyte Cellvibrio japonicus unravels the first step of xyloglucan degradation

scientific article

Functional characterization of xyloglucan glycosynthases from GH7, GH12, and GH16 scaffolds.

scientific article published on 6 May 2009

Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish

scientific article published on 04 March 2019

Genome analyses highlight the different biological roles of cellulases

scientific article published on 23 January 2012

GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease

scientific article published on October 2010

Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor.

scientific article published on 30 March 2018

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring

scientific article

Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics

scientific article

Glycosidase inhibition: assessing mimicry of the transition state

scientific article

Glycosidase mechanisms

scientific article published on 01 October 2002

Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases

scientific article published on 28 July 2020

Glycosyltransferases: structures, functions, and mechanisms

scientific article (publication date: 2008)

How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

scientific article published on 28 June 2005

How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

scientific article

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

scientific article

Identification of the Catalytic Nucleophile of Endoglucanase I fromFusarium oxysporumby Mass Spectrometry†

scientific article published on 01 May 1997

Identifying the Catalytic Acid/Base in GH29 α-l-Fucosidase Subfamilies

scientific article published on 13 August 2013

Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases

scientific article

In vitro and in vivo characterization of three Cellvibrio japonicus glycoside hydrolase family 5 members reveals potent xyloglucan backbone-cleaving functions.

scientific article published on 17 February 2018

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

scientific article published on 9 February 2015

Increase of enzyme activity through specific covalent modification with fragments.

scientific article published on 27 September 2017

Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

scientific article

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc–imidazole hybrid inhibitor

scientific article published on 29 September 2006

Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analyses

scientific article

Insight into a strategy for attenuating AmpC-mediated β-lactam resistance: Structural basis for selective inhibition of the glycoside hydrolase NagZ

scientific article

Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose

scientific article published on 03 March 2020

Insights into ligand-induced conformational change in Cel5A from Bacillus agaradhaerens revealed by a catalytically active crystal form

scientific article

Insights into the Structural Determinants of Cohesin—Dockerin Specificity Revealed by the Crystal Structure of the Type II Cohesin from Clostridium thermocellum SdbA

scientific article published on 01 June 2005

Insights into the molecular determinants of substrate specificity in glycoside hydrolase family 5 revealed by the crystal structure and kinetics of Cellvibrio mixtus mannosidase 5A.

scientific article published on 10 March 2004

Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components

scientific article

Insights into the synthesis of lipopolysaccharide and antibiotics through the structures of two retaining glycosyltransferases from family GT4.

scientific article

Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA

scientific article

Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin

scientific article

Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

scientific article published on 23 October 2019

Laccase

article published in 2011

Learning from microbial strategies for polysaccharide degradation

scientific article published on February 2016

Ligand-mediated dimerization of a carbohydrate-binding molecule reveals a novel mechanism for protein-carbohydrate recognition

scientific article published on March 2004

Lytic Polysaccharide Monooxygenases in Biomass Conversion

scientific article published on 12 October 2015

Lytic xylan oxidases from wood-decay fungi unlock biomass degradation

scientific article

Mannose foraging by Bacteroides thetaiotaomicron: structure and specificity of the beta-mannosidase, BtMan2A

scientific article

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

scientific article published on 03 September 2020

Mechanistic basis of substrate-O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study

scientific article published on 28 July 2020

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase

scientific article

Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors

scientific article

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

scientific article

Mechanistic insights into glycosidase chemistry

scientific article published on October 2008

Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: INTRACELLULAR  -O-LINKED N-GLYCOLYLGLUCOSAMINE (GlcNGc), UDP-GlcNGc, AND THE BIOCHEMICAL AND STRUCTURAL RATIONALE FOR THE SUBSTRATE TOLERANCE OF  -O-LINKED  -N-ACETYLGLUCOSAMINIDASE

scientific article

Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides

scientific article published on October 2017

Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues

scientific article

Molecular basis for inhibition of GH84 glycoside hydrolases by substituted azepanes: conformational flexibility enables probing of substrate distortion

scientific article

Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors

scientific article

Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum

scientific article

Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution

scientific article

NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides

scientific article

Nomenclature for sugar-binding subsites in glycosyl hydrolases

scientific article (publication date: 15 January 1997)

Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis

scientific article published in September 2004

On the catalytic mechanisms of lytic polysaccharide monooxygenases

scientific article published on 16 April 2016

Privateer: software for the conformational validation of carbohydrate structures

scientific article

Probing the beta-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants

scientific article

Probing the mechanism of ligand recognition in family 29 carbohydrate-binding modules.

scientific article

Production and spectroscopic characterization of lytic polysaccharide monooxygenases

scientific article published on 15 November 2018

Promiscuity in ligand-binding: The three-dimensional structure of a Piromyces carbohydrate-binding module, CBM29-2, in complex with cello- and mannohexaose

scientific article

Protein--carbohydrate interactions: learning lessons from nature.

scientific article

Purification, crystallisation and preliminary X-ray analysis of the vanadium-dependent haloperoxidase from Corallina officinalis

scientific article published on 01 February 1995

Purification, crystallization and preliminary X-ray analysis of the 3-phosphoglycerate kinase from Bacillus stearothermophilus

scientific article published on 01 October 1992

Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases

scientific article published on 26 February 2020

Recent insights into copper-containing lytic polysaccharide mono-oxygenases

scientific article published on 14 June 2013

Recent structural and mechanistic insights into post-translational enzymatic glycosylation

scientific article

Recent structural insights into the expanding world of carbohydrate-active enzymes

scientific article

Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates

scientific article published on 16 March 2020

Sequence and expression of the gene encoding 3-phosphoglycerate kinase from Bacillus stearothermophilus.

scientific article published on December 1991

Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module

scientific article

Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase

scientific article

Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases

scientific article

Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase

scientific article published on 21 June 2018

Structural Enzymology of Cellvibrio japonicus Agd31B Protein Reveals  -Transglucosylase Activity in Glycoside Hydrolase Family 31

scientific article

Structural analyses of enzymes involved in the O-GlcNAc modification

scientific article published on 30 July 2009

Structural analysis of a chimeric bacterial alpha-amylase. High-resolution analysis of native and ligand complexes

scientific article

Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases

scientific article published on 05 September 2018

Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance

scientific article published on 03 October 2019

Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans

scientific article

Structural and biochemical analysis of Cellvibrio japonicus xylanase 10C: how variation in substrate-binding cleft influences the catalytic profile of family GH-10 xylanases

scientific article

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases

scientific article

Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification

scientific article

Structural and functional insight into human O-GlcNAcase

scientific article published on 27 March 2017

Structural and kinetic dissection of the endo-α-1,2-mannanase activity of bacterial GH99 glycoside hydrolases from Bacteroides spp

scientific article

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

scientific article

Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation.

scientific article published on 22 August 2016

Structural and sequence-based classification of glycoside hydrolases

scientific article (publication date: October 1997)

Structural and thermodynamic analyses of α-L-fucosidase inhibitors

scientific article

Structural and thermodynamic dissection of specific mannan recognition by a carbohydrate binding module, TmCBM27

scientific article

Structural basis for cyclophellitol inhibition of a beta-glucosidase

scientific article

Structural basis for ligand binding and processivity in cellobiohydrolase Cel6A from Humicola insolens

scientific article

Structural characterization of human heparanase reveals insights into substrate recognition.

scientific article

Structural dissection and high-throughput screening of mannosylglycerate synthase

scientific article

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut.

scientific article

Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway

scientific article

Structural insight into industrially relevant glucoamylases: flexible positions of starch-binding domains.

scientific article published on 26 April 2018

Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum

scientific article

Structural insight into the mechanism of streptozotocin inhibition of O-GlcNAcase

scientific article

Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide

scientific article published on 19 October 2020

Structural studies of a surface-entropy reduction mutant of O-GlcNAcase

scientific article published on 08 January 2019

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors

scientific article

Structural studies of the unusual metal-ion site of the GH124 endoglucanase from Ruminiclostridium thermocellum

scientific article published on 01 August 2018

Structural studies on cellulases.

scientific article published in May 1998

Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors†,‡

scientific article published on 01 October 2006

Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases

scientific article published on 8 September 2004

Structure and Activity of Paenibacillus polymyxa Xyloglucanase from Glycoside Hydrolase Family 44

scientific article

Structure and FTIR spectra of 3 : 2 complexes of trimethylamine N-oxide and 4-dimethylamine-2,6-dimethylpyridine N-oxide with perchloric acid

Structure and activity of the Streptococcus pyogenes family GH1 6-phospho-β-glucosidase SPy1599

scientific article

Structure and activity of the Streptomyces coelicolor A3(2) β-N-acetylhexosaminidase provides further insight into GH20 family catalysis and inhibition

scientific article

Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases.

scientific article published on 23 January 2006

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

scientific article

Structure and function of Bs164 β-mannosidase from Bacteroides salyersiae the founding member of glycoside hydrolase family GH164

scientific article published on 22 December 2019

Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae

scientific article published on 02 October 2018

Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase

scientific article published in 2010

Structure and kinetics of a monomeric glucosamine 6-phosphate deaminase: missing link of the NagB superfamily?

scientific article

Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains

scientific article (publication date: 28 March 2003)

Structure determination and refinement of the Humicola insolens endoglucanase V at 1.5 A resolution.

scientific article

Structure of a Bacillus halmapalus family 13 alpha-amylase, BHA, in complex with an acarbose-derived nonasaccharide at 2.1 A resolution

scientific article

Structure of a GH51 α-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi

scientific article published on 16 October 2020

Structure of a Talaromyces pinophilus GH62 arabinofuranosidase in complex with AraDNJ at 1.25 Å resolution

Structure of a carbohydrate esterase from Bacillus anthracis

scientific article published on 01 January 2007

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

scientific article published on 16 February 2006

Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix

scientific article

Structure of a pullulanase from Bacillus acidopullulyticus

scientific article

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation

scientific article

Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

scientific article published on 05 November 2020

Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 A.

scientific article published on March 1994

Structure of the Aspergillus oryzae α-Amylase Complexed with the Inhibitor Acarbose at 2.0 Å Resolution,

scientific article published on September 9, 1997

Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 A and its cellobiose complex at 2.0 A resolution

scientific article

Structure of the GH76 α-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron

scientific article

Structure of the GH9 glucosidase/glucosaminidase from Vibrio cholerae

Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis

scientific article

Structure of the catalytic core module of the Chaetomium thermophilum family GH6 cellobiohydrolase Cel6A

scientific article

Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms

scientific article

Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family

scientific article

Structures and mechanisms of glycosyl hydrolases

scientific article (publication date: 15 September 1995)

Substrate Distortion by a Lichenase Highlights the Different Conformational Itineraries Harnessed by Related Glycoside Hydrolases

scientific article published on 01 August 2006

Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase

scientific article

Substrate distortion by a beta-mannanase: snapshots of the Michaelis and covalent-intermediate complexes suggest a B(2,5) conformation for the transition state

scientific article

Sweet secrets of synthesis.

scientific article

Synthetic and Crystallographic Insight into Exploiting sp2 Hybridization in the Development of α-l-Fucosidase Inhibitors

scientific article published on 18 March 2019

Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A.

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The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions

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The Cellvibrio japonicus Mannanase CjMan26C Displays a Unique exo-Mode of Action That Is Conferred by Subtle Changes to the Distal Region of the Active Site

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The Clostridium cellulolyticum dockerin displays a dual binding mode for its cohesin partner

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The Contribution of Non-catalytic Carbohydrate Binding Modules to the Activity of Lytic Polysaccharide Monooxygenases

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The Copper Active Site of CBM33 Polysaccharide Oxygenases

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The GH130 Family of Mannoside Phosphorylases Contains Glycoside Hydrolases That Target β-1,2-Mannosidic Linkages in Candida Mannan

scientific article published on 18 August 2015

The X-ray crystal structure of an Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase reveals a (beta/alpha)(8) catalytic domain, two ancillary domains and active site residues key for transglycosylation activity

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The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: structure and biochemistry of the Clostridium thermocellum X6b domain

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The alpha-glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants

scientific article (publication date: 30 May 2003)

The case of the missing base

scientific article published on 28 October 2012

The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration

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The crystal structure of human muscle aldolase at 3.0 A resolution.

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The crystal structure of the catalytic core domain of endoglucanase I from Trichoderma reesei at 3.6 A resolution, and a comparison with related enzymes

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The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity

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The crystallization and structural analysis of cellulases (and other glycoside hydrolases): strategies and tactics

scientific article published on January 2012

The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution

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The mechanisms by which family 10 glycoside hydrolases bind decorated substrates

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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases.

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The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach

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The structural basis for catalysis and specificity of the Pseudomonas cellulosa alpha-glucuronidase, GlcA67A

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The structure of a family GH25 lysozyme fromAspergillus fumigatus

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The structure of the AliC GH13 α-amylase from Alicyclobacillus sp. reveals the accommodation of starch branching points in the α-amylase family

scientific article published on 04 January 2019

The structure of the feruloyl esterase module of xylanase 10B from Clostridium thermocellum provides insights into substrate recognition

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The sulfoquinovosyl glycerol binding protein SmoF binds and accommodates plant sulfolipids

scientific article published on 07 March 2022

The three-dimensional structure of the N-acetylglucosamine-6-phosphate deacetylase, NagA, from Bacillus subtilis: a member of the urease superfamily

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The three-dimensional structure of the cellobiohydrolase Cel7A from Aspergillus fumigatus at 1.5 Å resolution

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The use of forced protein evolution to investigate and improve stability of family 10 xylanases. The production of Ca2+-independent stable xylanases

scientific article published on 27 September 2004

Three dimensional structure of a bacterial α-l-fucosidase with a 5-membered iminocyclitol inhibitor

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Three-Dimensional Structures of UDP-Sugar Glycosyltransferases Illuminate the Biosynthesis of Plant Polysaccharides

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Three-dimensional structure of a thermophilic family GH11 xylanase fromThermobifida fusca

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Three-dimensional structure of a variant `Termamyl-like' Geobacillus stearothermophilus α-amylase at 1.9 Å resolution

scientific article published on January 2015

Three-dimensional structure of aStreptomyces sviceusGNAT acetyltransferase with similarity to the C-terminal domain of the human GH84O-GlcNAcase

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Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases

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Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families

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Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

scientific article published on 8 November 2017

Trapped in the act of catalysis

scientific article published on 01 May 1999

Understanding how diverse beta-mannanases recognize heterogeneous substrates

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Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors

scientific article published in 2019

Validation tools: can they indicate the information content of macromolecular crystal structures?

scientific article published in June 1998

Visualizing the reaction coordinate of an O-GlcNAc hydrolase

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X-ray crystal structure of a non-crystalline cellulose-specific carbohydrate-binding module: CBM28.

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YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids

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α-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies

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