List of works - Lily Jan

A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles.

scientific article

A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating

scientific article published on December 2013

A fluorescent probe designed for studying protein conformational change

scientific article

A gate keeper for axonal transport.

scientific article published in March 2009

A potassium channel, the M-channel, as a therapeutic target

scientific article

A quantitative assessment of models for voltage-dependent gating of ion channels

scientific article

A twist on potassium channel gating

scientific article published in June 2010

Activation of orexin system facilitates anesthesia emergence and pain control

article published in the Proceedings of the National Academy of Sciences of the United States of America

An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging

scientific article

Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels

scientific article (publication date: April 1997)

Ca2+-activated Cl− channels at a glance ⬇️

scientific article published on March 15, 2012

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

scientific article

Channeling to the nucleus.

scientific article published in December 2006

Chapter 8 The molecular organization of voltage-dependent K+ channels in vivo

Chemically induced vesiculation as a platform for studying TMEM16F activity

scientific article published on 08 January 2019

Chloride channels regulate differentiation and barrier functions of the mammalian airway

scientific article published on 14 April 2020

Cloning and heterologous expression of new xANO2 from Xenopus laevis

scientific article published on 20 April 2011

Common variants associated with general and MMR vaccine-related febrile seizures

scientific article published on 26 October 2014

Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons

scientific article

Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity

scientific article

Conduits of life's spark: a perspective on ion channel research since the birth of neuron

scientific article published on October 2013

Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

scholarly article

Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.

scientific article published on February 2009

Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification

scientific article published on March 2004

Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling

scientific article

Dendrites of Distinct Classes of Drosophila Sensory Neurons Show Different Capacities for Homotypic Repulsion ⬇️

scientific article published on April 15, 2003

Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons

scientific article published in March 2003

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury.

scientific article published on 29 October 2015

Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila ⬇️

scientific article published on June 1, 2011

Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism

scientific article

Drosophila egg-laying site selection as a system to study simple decision-making processes

scientific article published on March 2008

Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity

scientific article published on 18 July 2019

EAG2 potassium channel with evolutionarily conserved function as a brain tumor target

scientific article

Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila

scientific article

Epilepsy genes: excitement traced to potassium channels

article

Erratum: Multiple potassium-channel components are produced by alternative splicing at the shaker locus in Drosophila

scientific article published in Nature

Expression Profile of Aging and Oxidative Stress Response in Drosophila melanogaster

scientific article published on 12 October 2001

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

scientific article

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

scientific article

Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.

scientific article

Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.

scientific article

G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

scientific article published in September 1997

Genetic and physiologic dissection of the vertebrate cardiac conduction system

scientific article

Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene

scientific article

Growing dendrites and axons differ in their reliance on the secretory pathway

scientific article published on August 2007

Identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling

scientific article published in March 2007

Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.

scientific article

Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning

scientific article published in August 2006

Identification of yeast proteins necessary for cell-surface function of a potassium channel

scientific article

Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells

scientific article published on 10 September 2013

Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning

scientific article published in August 2017

Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics

scientific article published on 16 May 2018

International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.

scientific article

International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels ⬇️

scientific article

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels

scientific article (publication date: December 2003)

Ion channel genes and human neurological disease: recent progress, prospects, and challenges.

scientific article

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

scientific article published on 10 November 2010

Lily Jan.

scientific article published in March 2014

M-channels: neurological diseases, neuromodulation, and drug development.

scientific article

MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development

scientific journal article

Making antisense of pain

scientific article published in August 2013

Mammalian electrophysiology on a microfluidic platform

scientific article

Mechanisms of distribution and targeting of neuronal ion channels

scientific article published on September 1, 2010

Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs

Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

scientific article

N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels

scientific article published on 5 July 2016

Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1 ⬇️

scientific article published on March 1, 2011

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.

scientific article published in November 2015

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

scientific journal article

Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains

scientific article

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche

scientific journal article

Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.

scientific article

Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants

scientific article published in December 1997

Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology

scientific article published on January 2007

Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis

scientific article

Retrospective: Seymour Benzer (1921-2007).

scientific article

Signalling mechanisms: a decade of signalling.

scientific article

Spider toxins selectively block calcium currents in Drosophila.

scientific article published on December 1989

Stoichiometry of Kir channels with phosphatidylinositol bisphosphate

scientific article published on 01 January 2008

Structure, function and pharmacology of human itch GPCRs

scientific article published on 17 November 2021

Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense

scientific article

TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation.

scientific article published on 29 December 2016

TMEM16B Calcium-Activated Chloride Channels Regulate Action Potential Firing in Lateral Septum and Aggression in Male Mice

scientific article published on 18 July 2019

TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala

scientific article published on 04 September 2019

Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization

scientific journal article

Targeting potassium channels in cancer

scientific article

The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts.

scientific article published on February 2003

The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel

scientific article published on 22 February 2018

The distribution and targeting of neuronal voltage-gated ion channels

scientific article published on July 2006

The isomeric configuration of the bacteriorhodopsin chromophore

scientific article published on October 1, 1975

The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12.

scientific article published in October 1987

Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

scientific article published on 01 July 2019

Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

scientific article published on 28 May 2019

Thrilling moment of an inhibitory channel.

scientific article published on June 2008

Tiling of the Drosophila epidermis by multidendritic sensory neurons.

scientific article published in June 2002

Turning G proteins on and off using peptide ligands

scientific article

Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics

scientific article

List of works by Lily Jan

A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles.

A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating

A fluorescent probe designed for studying protein conformational change

A gate keeper for axonal transport.

A potassium channel, the M-channel, as a therapeutic target

A quantitative assessment of models for voltage-dependent gating of ion channels

A twist on potassium channel gating

Activation of orexin system facilitates anesthesia emergence and pain control

An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging

Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels

Ca2+-activated Cl− channels at a glance ⬇️

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

Channeling to the nucleus.

Chapter 8 The molecular organization of voltage-dependent K+ channels in vivo

Chemically induced vesiculation as a platform for studying TMEM16F activity

Chloride channels regulate differentiation and barrier functions of the mammalian airway

Cloning and heterologous expression of new xANO2 from Xenopus laevis

Common variants associated with general and MMR vaccine-related febrile seizures

Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons

Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity

Conduits of life's spark: a perspective on ion channel research since the birth of neuron

Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.

Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification

Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling

Dendrites of Distinct Classes of Drosophila Sensory Neurons Show Different Capacities for Homotypic Repulsion ⬇️

Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury.

Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila ⬇️

Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism

Drosophila egg-laying site selection as a system to study simple decision-making processes

Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity

EAG2 potassium channel with evolutionarily conserved function as a brain tumor target

Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila

Epilepsy genes: excitement traced to potassium channels

Erratum: Multiple potassium-channel components are produced by alternative splicing at the shaker locus in Drosophila

Expression Profile of Aging and Oxidative Stress Response in Drosophila melanogaster

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.

Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.

G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

Genetic and physiologic dissection of the vertebrate cardiac conduction system

Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene

Growing dendrites and axons differ in their reliance on the secretory pathway

Identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling

Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.

Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning

Identification of yeast proteins necessary for cell-surface function of a potassium channel

Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells

Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning

Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics

International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.

International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels ⬇️

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels

Ion channel genes and human neurological disease: recent progress, prospects, and challenges.

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

Lily Jan.

M-channels: neurological diseases, neuromodulation, and drug development.

MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development

Making antisense of pain

Mammalian electrophysiology on a microfluidic platform

Mechanisms of distribution and targeting of neuronal ion channels

Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs

Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels

Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1 ⬇️

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche

Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.

Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants

Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology

Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis

Retrospective: Seymour Benzer (1921-2007).

Signalling mechanisms: a decade of signalling.

Spider toxins selectively block calcium currents in Drosophila.