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List of works by Vijayalakshmi Ravindranath

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine

scientific article

Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid

scientific article published on 16 March 2007

Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues

scientific article published on June 2006

An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites

scientific article published in August 2007

An unsymmetrical diarylheptanoid from Curcuma longa

scientific article published on 25 July 2002

Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.

scientific article

CaV1.3 L-Type Calcium Channels Increase the Vulnerability of Substantia Nigra Dopaminergic Neurons in MPTP Mouse Model of Parkinson's Disease

scientific article published on 01 January 2019

Complex I assay in mitochondrial preparations from CNS.

scientific article published in January 2008

Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain

scientific article published on 20 September 2007

Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain

scientific article published in May 2005

Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain

scientific article published in June 2002

Critical cysteines in Akt1 regulate its activity and proteasomal degradation: implications for neurodegenerative diseases

scientific article

Cytochrome P450-mediated metabolism in brain: functional roles and their implications

scientific article published on 18 January 2013

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation

scientific article published on 02 April 2011

DJ-1 loss by glutaredoxin but not glutathione depletion triggers Daxx translocation and cell death

scientific article

Detection and localization of protein-acetaldehyde adducts in rat brain after chronic ethanol treatment

scientific article

Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS.

scientific article published on 14 November 2006

Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: implications in excitotoxicity

scientific article

Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite

scientific article

Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration

scientific article

Fenofibrate reduces mortality and precludes neurological deficits in survivors in murine model of Japanese encephalitis viral infection

scientific article

Gamma-glutamyl cysteine synthetase is up-regulated during recovery of brain mitochondrial complex I following neurotoxic insult in mice

scientific article published in October 2003

Glutaredoxin 1 Downregulation in the Substantia Nigra Leads to Dopaminergic Degeneration in Mice

scientific article published on 03 July 2020

Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP.

scientific article published on 19 February 2003

Glutaredoxin1 Diminishes Amyloid Beta-Mediated Oxidation of F-Actin and Reverses Cognitive Deficits in an Alzheimer's Disease Mouse Model

scientific article published on 01 December 2019

Grand challenges in global mental health

scientific article

Inhibition of cystathionine-gamma-lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS.

scientific article published on 13 November 2006

Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects

scientific article published in Scientific Reports

Knockdown of cytosolic glutaredoxin 1 leads to loss of mitochondrial membrane potential: implication in neurodegenerative diseases

scientific article

MPTP activates ASK1-p38 MAPK signaling pathway through TNF-dependent Trx1 oxidation in parkinsonism mouse model

scientific article

Neurolathyrism: mitochondrial dysfunction in excitotoxicity mediated by L-beta-oxalyl aminoalanine

scientific article

Occurrence, distribution and potential actions of CYP2D6 in the brain

Presence of splice variant forms of cytochrome P4502D1 in rat brain but not in liver

scientific article published in April 2005

Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.

scientific article

Redox activated MAP kinase death signaling cascade initiated by ASK1 is not activated in female mice following MPTP: novel mechanism of neuroprotection.

scientific article

Redox modification of Akt mediated by the dopaminergic neurotoxin MPTP, in mouse midbrain, leads to down-regulation of pAkt

scientific article published on 23 December 2011

Regional research priorities in brain and nervous system disorders

scientific article

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease

scientific article

Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.

scientific article published in November 2008

The influence of MTR A2756G polymorphism on plasma homocysteine in young south Indians

scientific article published in May 2008

Thiol Oxidation by Diamide Leads to Dopaminergic Degeneration and Parkinsonism Phenotype in Mice: A Model for Parkinson's Disease

scientific article published on 27 April 2016

Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury.

scientific article published in October 2002

Toxicological consequences of differential regulation of cytochrome p450 isoforms in rat brain regions by phenobarbital

scientific article published in March 2002

Withania somnifera Extract Protects Model Neurons from In Vitro Traumatic Injury

scientific article published in July 2017

Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver

scientific article published on 30 January 2012

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

scientific article published on 05 July 2020

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