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List of works by Jane Visvader

1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex

scientific article (publication date: June 2002)

A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer

scientific article published on 05 December 2018

A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3

scientific journal article

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

scientific article

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.

scientific article

A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

scientific article published on 05 May 2021

Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells ⬇️

scientific article published on November 1, 2010

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

scientific article published on 2 August 2009

Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation

scientific article published in 2021

Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells.

scientific article published in February 2012

BARD1 variants are not associated with breast cancer risk in Australian familial breast cancer

article

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

scientific article published in Nature Communications

Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

article

Breast cancer risk and the BRCA1 interacting protein CTIP

scientific article published on 20 December 2007

CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity

scientific article (publication date: September 2002)

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

scientific article

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

scientific article

Cancer stem cells: current status and evolving complexities

scientific article published on June 2012

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

scientific article published on 06 August 2018

Cell fate takes a slug in BRCA1-associated breast cancer ⬇️

scientific article published on April 6, 2011

Cellular Mechanisms Underlying Intertumoral Heterogeneity

scientific article published on 28 September 2015

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer

scientific article

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer

scientific article published in Nature Communications

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.

scientific article published on 20 November 2017

Control of mammary stem cell function by steroid hormone signalling.

scientific article published on 11 April 2010

Crystallization of FLINC4, an intramolecular LMO4-ldb1 complex

scientific article

Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland

scientific article

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1

scientific journal article

Derivation of a robust mouse mammary organoid system for studying tissue dynamics

scientific article

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

scientific article

Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR.

scientific article published on 28 November 2017

Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif

scientific article published on 14 April 2004

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

scientific article

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

scientific article

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.

scientific article published on 18 July 2014

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

scientific article published on 03 April 2020

Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?

scientific article

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

scientific article

Early asymmetry of gene transcription in embryonic human left and right cerebral cortex

scientific article

Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression

scientific article published on 16 February 2017

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

scientific article

Essential role for a novel population of binucleated mammary epithelial cells in lactation.

scientific article

Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer

scientific article published on 16 April 2009

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

scientific article

Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

scientific article published on 25 October 2018

Frequency of the ATM IVS10-6T-->G variant in Australian multiple-case breast cancer families

scientific article

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

scientific article published on 3 February 2009

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

scientific article

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

scientific article published on 19 September 2011

Generation of a functional mammary gland from a single stem cell

scientific article (publication date: 5 January 2006)

Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.

scientific article

Grhl3 and Lmo4 play coordinate roles in epidermal migration

scientific article published on 26 June 2008

Halting triple negative breast cancer by targeting PROCR

scientific article published on 01 November 2019

High-resolution 3D imaging of fixed and cleared organoids

scientific article published on 03 May 2019

Identification of Taxreb107 as a lactogenic hormone responsive gene in mammary epithelial cells

scientific article published on October 2003

Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.

scientific article

Identification of the key LMO2-binding determinants on Ldb1.

scientific article published on 20 March 2006

Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium

scientific article published in April 2009

In situ identification of bipotent stem cells in the mammary gland.

scientific article published on 26 January 2014

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice

scientific article published on 9 January 2012

Insights into the cell of origin in breast cancer and breast cancer stem cells

scientific article published on June 2010

Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits

scientific article published on 18 June 2015

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

scientific article published on 01 June 2019

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

scientific article published on 28 March 2019

Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

scientific article

Isolation and Propagation of Mammary Epithelial Stem and Progenitor Cells

scientific article published on 01 January 2019

Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods

scientific article published on 30 May 2012

Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?

scientific article published on 25 May 2011

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

scientific article

Knocking off SOCS genes in the mammary gland.

scientific article published on 20 April 2007

LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

scientific article published on December 2003

LMO4 expression in squamous cell carcinoma of the anterior tongue.

scientific article

Letter to the Editor: (1)H, (15)N and (13)C assignments of FLIN4, an intramolecular LMO4:ldb1 complex

Lgr5+ pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

scientific article published on 05 September 2019

Lineage Tracing of Mammary Stem and Progenitor Cells

scientific article published on 01 January 2017

Lineage enforcement by inductive mesenchyme on adult epithelial stem cells across developmental germ layers

scientific article

Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

scientific article

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

scientific article published on 10 March 2021

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

scientific article

Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development

scientific article published in July 2005

Mammary stem cells and mammopoiesis

scientific article published on October 2006

Mammary stem cells and their regulation by steroid hormones

scientific article published on 01 May 2011

Modeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoids

scientific article published on 07 October 2019

Murine Mammary Epithelial Stem Cells: Discovery, Function, and Current Status ⬇️

scientific article published on February 1, 2011

Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer

scientific article

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas

scientific article (publication date: 20 October 2003)

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

scientific article

Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

scientific article published in October 2008

Out-RANKing BRCA1 in Mutation Carriers.

scientific article published on 19 January 2017

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

scientific article

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

scientific article published on 27 December 2016

Patient-derived xenograft models of breast cancer and their predictive power

scientific article

Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.

scientific article published on 7 June 2016

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

scientific article published on 12 March 2021

Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations.

scientific article

Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

scientific article published on 24 April 2019

R code and downstream analysis objects for the scRNA-seq atlas of normal and tumorigenic human breast tissue

publication published on 23 March 2022

RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.

scientific article published on 20 June 2016

RE: Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article published on 4 April 2017

ROAST: rotation gene set tests for complex microarray experiments

scientific article

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

scientific article published on 13 April 2016

Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4

scientific journal article

Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli

scientific article published on 11 October 2012

Replication of in vitro constructed viroid mutants: location of the pathogenicity-modulating domain of citrus exocortis viroid.

scientific article published on September 1986

Resident macrophages influence stem cell activity in the mammary gland

scientific article published on 26 August 2009

Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer

scientific article

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

scientific article

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

scientific article published on 18 July 2011

Shedding light on mammary stem cells and tumorigenesis

scientific article

Single cell transcriptome atlas of mouse mammary epithelial cells across development

scientific article published on 29 June 2021

Socs2 and elf5 mediate prolactin-induced mammary gland development

scientific journal article

StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.

scientific article

Stem Cells and the Differentiation Hierarchy in Mammary Gland Development

scientific article published on 20 September 2019

Stem cells and cancer - the promise and puzzles

scientific article published on 27 July 2010

Steroid hormone receptor status of mouse mammary stem cells

scientific article

Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

scientific article

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer

scientific article published in August 2017

Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex

scientific article published on 2 September 2004

Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer

scientific article

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

scientific article published on 27 April 2020

The Ets transcription factor Elf5 specifies mammary alveolar cell fate

scientific article

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

scientific article

The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues

scientific article published on April 2005

The complexities and caveats of lineage tracing in the mammary gland.

scientific article published on 25 November 2016

The emerging picture of the mouse mammary stem cell

scientific article published on June 2007

The future of mammary stem cell biology: the power of in vivo transplants

scientific article published on 29 May 2008

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

scientific article published on 01 October 2008

The mammary stem cell hierarchy.

scientific article published on January 2014

The molecular culprits underlying precocious mammary gland involution

scientific article published on March 2007

The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation

scientific article published on May 2004

The unmasking of novel unipotent stem cells in the mammary gland

scientific article published on 8 November 2011

Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins

scientific article

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling

scientific article published on 27 April 2020

Tissue-specific designs of stem cell hierarchies

scientific article published on 21 March 2016

Transcription factor Lmo4 defines the shape of functional areas in developing cortices and regulates sensorimotor control

scientific article published on 16 December 2008

Transcriptional regulators in mammary gland development and cancer

scientific article

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

scientific article

Two promoters within the human LMO4 gene contribute to its overexpression in breast cancer cells

scientific article published on September 2003

c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.

scientific article

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