List of works - Robert Tycko

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

scientific article

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

scientific article published on 17 January 2006

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

scientific article

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

scientific article published on September 12, 2013

Molecular structure of amyloid fibrils: insights from solid-state NMR.

scientific article published on February 2006

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

scientific article published on 3 November 2007

Solid-State NMR Studies of Amyloid Fibril Structure

scientific article published on January 1, 2011

Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure

scientific article

Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

scientific article

Progress towards a molecular-level structural understanding of amyloid fibrils

scientific article published on February 2004

Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

scholarly article

Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils

scientific article published on March 8, 2012

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

scientific article published on January 7, 2013

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

scientific article published on 04 January 2017

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

article

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance

scientific article published in December 2002

Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

scientific article

Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide

scientific article

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

scientific article published on May 6, 2015

Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains

scientific article

Amyloid of Rnq1p, the basis of the [PIN+] prion, has a parallel in-register beta-sheet structure

scientific article

Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance

scientific article published on 23 October 2007

Alignment of Biopolymers in Strained Gels: A New Way To Create Detectable Dipole−Dipole Couplings in High-Resolution Biomolecular NMR

article

Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p

scientific article published in August 2005

The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance

scientific article

Physical and structural basis for polymorphism in amyloid fibrils

scientific article published on September 13, 2014

Insights into the amyloid folding problem from solid-state NMR

article

Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings

scientific article published on August 28, 2012

Symmetry-based constant-time homonuclear dipolar recoupling in solid state NMR

article

The functional curli amyloid is not based on in-register parallel beta-sheet structure

scientific article published on July 2009

Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils

scientific article

Measurement of sample temperatures under magic-angle spinning from the chemical shift and spin-lattice relaxation rate of 79Br in KBr powder

scientific article published on 25 September 2008

Measurement of amyloid fibril mass-per-length by tilted-beam transmission electron microscopy

scientific article

Probing site-specific conformational distributions in protein folding with solid-state NMR

scientific article

Low-temperature dynamic nuclear polarization at 9.4 T with a 30 mW microwave source

scientific article

Polymorph-Specific Kinetics and Thermodynamics of β-Amyloid Fibril Growth

scientific article published on April 29, 2013

Two prion variants of Sup35p have in-register parallel beta-sheet structures, independent of hydration

scientific article published on June 2009

Structural Evolution of Iowa Mutant β-Amyloid Fibrils from Polymorphic to Homogeneous States under Repeated Seeded Growth

scientific article published on February 28, 2011

Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel

scientific article

Constraints on supramolecular structure in amyloid fibrils from two-dimensional solid-state NMR spectroscopy with uniform isotopic labeling

scientific article published in June 2003

Biomolecular solid state NMR with magic-angle spinning at 25K

scientific article

Adiabatic Rotational Splittings and Berry's Phase in Nuclear Quadrupole Resonance

scientific article

Structure and dynamics of the HIV-1 Vpu transmembrane domain revealed by solid-state NMR with magic-angle spinning

article

Amyloids of shuffled prion domains that form prions have a parallel in-register beta-sheet structure

article

Detection of a transient intermediate in a rapid protein folding process by solid-state nuclear magnetic resonance

scientific article

Perturbation of nuclear spin polarizations in solid state NMR of nitroxide-doped samples by magic-angle spinning without microwaves

scientific article published on May 14, 2014

The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40 into Atypical Fibrils by ΔE22-Aβ1−39

scientific article (publication date: 29 March 2011)

Site-Specific Identification of Non-β-Strand Conformations in Alzheimer's β-Amyloid Fibrils by Solid-State NMR

scientific article published on May 1, 2003

Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network

scientific article published on July 27, 2015

Oligomerization state and supramolecular structure of the HIV‐1 Vpu protein transmembrane segment in phospholipid bilayers

scientific article published on October 1, 2010

List of works by Robert Tycko

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

Molecular structure of amyloid fibrils: insights from solid-state NMR.

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

Solid-State NMR Studies of Amyloid Fibril Structure

Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure

Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

Progress towards a molecular-level structural understanding of amyloid fibrils

Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance

Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains

Amyloid of Rnq1p, the basis of the [PIN+] prion, has a parallel in-register beta-sheet structure

Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance

Alignment of Biopolymers in Strained Gels: A New Way To Create Detectable Dipole−Dipole Couplings in High-Resolution Biomolecular NMR

Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p

The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance

Physical and structural basis for polymorphism in amyloid fibrils

Insights into the amyloid folding problem from solid-state NMR

Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings

Symmetry-based constant-time homonuclear dipolar recoupling in solid state NMR

The functional curli amyloid is not based on in-register parallel beta-sheet structure

Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils

Measurement of sample temperatures under magic-angle spinning from the chemical shift and spin-lattice relaxation rate of 79Br in KBr powder

Measurement of amyloid fibril mass-per-length by tilted-beam transmission electron microscopy

Probing site-specific conformational distributions in protein folding with solid-state NMR

Low-temperature dynamic nuclear polarization at 9.4 T with a 30 mW microwave source

Polymorph-Specific Kinetics and Thermodynamics of β-Amyloid Fibril Growth

Two prion variants of Sup35p have in-register parallel beta-sheet structures, independent of hydration

Structural Evolution of Iowa Mutant β-Amyloid Fibrils from Polymorphic to Homogeneous States under Repeated Seeded Growth

Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel

Constraints on supramolecular structure in amyloid fibrils from two-dimensional solid-state NMR spectroscopy with uniform isotopic labeling

Biomolecular solid state NMR with magic-angle spinning at 25K

Adiabatic Rotational Splittings and Berry's Phase in Nuclear Quadrupole Resonance

Structure and dynamics of the HIV-1 Vpu transmembrane domain revealed by solid-state NMR with magic-angle spinning

Amyloids of shuffled prion domains that form prions have a parallel in-register beta-sheet structure

Detection of a transient intermediate in a rapid protein folding process by solid-state nuclear magnetic resonance

Perturbation of nuclear spin polarizations in solid state NMR of nitroxide-doped samples by magic-angle spinning without microwaves

The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40 into Atypical Fibrils by ΔE22-Aβ1−39

Site-Specific Identification of Non-β-Strand Conformations in Alzheimer's β-Amyloid Fibrils by Solid-State NMR

Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network

Oligomerization state and supramolecular structure of the HIV‐1 Vpu protein transmembrane segment in phospholipid bilayers