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List of works by Dieter Langosch

A solid-state NMR study of changes in lipid phase induced by membrane-fusogenic LV-peptides

scientific article published on 30 October 2009

Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization

scientific article

An extended ToxR POSSYCCAT system for positive and negative selection of self-interacting transmembrane domains

scientific article published on 6 February 2007

BLaTM 2.0, a Genetic Tool Revealing Preferred Antiparallel Interaction of Transmembrane Helix 4 of the Dual-Topology Protein EmrE.

scientific article published on 18 April 2017

Complex patterns of histidine, hydroxylated amino acids and the GxxxG motif mediate high-affinity transmembrane domain interactions

scientific article

De novo design of conformationally flexible transmembrane peptides driving membrane fusion

scholarly article

Direct visualization of large and protein-free hemifusion diaphragms

scientific article

Entrapment of Water at the Transmembrane Helix-Helix Interface of Quiescin Sulfhydryl Oxidase 2.

scientific article

Functions of SNAREs in intracellular membrane fusion and lipid bilayer mixing

scientific article

Gas-phase behavior of noncovalent transmembrane segment complexes

scientific article published in December 2008

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

scientific article published in March 2007

Homodimerization Protects the Amyloid Precursor Protein C99 Fragment from Cleavage by γ-Secretase

scientific article published on 24 September 2015

Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions

scientific article

In vitro selection of self-interacting transmembrane segments--membrane proteins approached from a different perspective

scientific article

Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer's Disease Mutant of APP

scholarly article published 19 July 2018

Interaction and conformational dynamics of membrane-spanning protein helices

scientific article published on July 2009

Ionic interactions promote transmembrane helix-helix association depending on sequence context

scientific article

Is lipid flippase activity of SNARE transmembrane domains required for membrane fusion? ⬇️

scientific article published on March 5, 2011

Phenylalanine promotes interaction of transmembrane domains via GxxxG motifs

scientific article published on 26 September 2007

Role of GxxxG Motifs in Transmembrane Domain Interactions

scientific article published on 05 August 2015

Self-interaction of a SNARE transmembrane domain promotes the hemifusion-to-fusion transition

scientific article

Self-interaction of transmembrane helices representing pre-clusters from the human single-span membrane proteins ⬇️

scientific article published on July 1, 2013

Sequence-specific conformational flexibility of SNARE transmembrane helices probed by hydrogen/deuterium exchange

scientific article

Sequence‐dependent backbone dynamics of a viral fusogen transmembrane helix ⬇️

scientific article published on June 11, 2012

Side-chain to main-chain hydrogen bonding controls the intrinsic backbone dynamics of the amyloid precursor protein transmembrane helix

scientific article published on March 2014

Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u

scientific article

Solid-phase extraction as a tool to remove impurities and small fragments from synthetic peptides

scientific article published in September 2005

Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides

scientific article published in February 2007

Stabilization of conformationally dynamic helices by covalently attached acyl chains

scientific article published on August 2009

Structural features of fusogenic model transmembrane domains that differentially regulate inner and outer leaflet mixing in membrane fusion

scientific article published in January 2010

Substrate processing in intramembrane proteolysis by γ-secretase - the role of protein dynamics

scientific article published on 15 November 2016

Synaptobrevin transmembrane domain dimerization-revisited

scientific article published in May 2004

The Backbone Dynamics of the Amyloid Precursor Protein Transmembrane Helix Provides a Rationale for the Sequential Cleavage Mechanism of γ-Secretase ⬇️

scientific article published on January 16, 2013

The cleavage domain of the amyloid precursor protein transmembrane helix does not exhibit above-average backbone dynamics

scientific article

The interface between self-assembling erythropoietin receptor transmembrane segments corresponds to a membrane-spanning leucine zipper

scientific article published on 5 November 2003

The interface of a membrane-spanning leucine zipper mapped by asparagine-scanning mutagenesis

scientific article published in February 2004

Tryptophan supports interaction of transmembrane helices

scientific article published on 21 October 2005

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