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List of works by Mark Johannes van der Laan

<b>ltmle</b>: An <i>R</i> Package Implementing Targeted Minimum Loss-Based Estimation for Longitudinal Data

scientific article published in 2017

A Case Study of the Impact of Data-Adaptive Versus Model-Based Estimation of the Propensity Scores on Causal Inferences from Three Inverse Probability Weighting Estimators

scientific article published on 01 May 2016

A General Implementation of TMLE for Longitudinal Data Applied to Causal Inference in Survival Analysis ⬇️

scientific article published on September 18, 2012

A Generally Efficient Targeted Minimum Loss Based Estimator based on the Highly Adaptive Lasso.

scientific article published on 12 October 2017

A Targeted Maximum Likelihood Estimator of a Causal Effect on a Bounded Continuous Outcome ⬇️

scientific article published on January 1, 2010

A causal inference approach for constructing transcriptional regulatory networks

scientific article published on 30 August 2005

A comparison of methods to control type I errors in microarray studies.

scientific article published on 11 October 2007

A cross-validation deletion-substitution-addition model selection algorithm: Application to marginal structural models

scientific article

A double robust approach to causal effects in case-control studies

scientific article published on 31 January 2014

A doubly robust censoring unbiased transformation

scientific article published in January 2007

A fundamental measure of treatment effect heterogeneity

scientific article published in 2021

A machine learning-based approach for estimating and testing associations with multivariate outcomes

scientific article published on 12 August 2020

A method to increase the power of multiple testing procedures through sample splitting.

scientific article published in August 2006

A new approach to hierarchical data analysis: Targeted maximum likelihood estimation for the causal effect of a cluster-level exposure

scientific article published on 19 June 2018

A novel targeted learning method for quantitative trait loci mapping

scientific article published on 24 September 2014

A practical illustration of the importance of realistic individualized treatment rules in causal inference

scientific article published on January 2007

A randomized, controlled trial of in-home drinking water intervention to reduce gastrointestinal illness

scientific article published in March 2005

A statistical method for constructing transcriptional regulatory networks using gene expression and sequence data

scientific article published in March 2005

A targeted maximum likelihood estimator for two-stage designs

scientific article published on 11 March 2011

ADAPTIVE MATCHING IN RANDOMIZED TRIALS AND OBSERVATIONAL STUDIES.

scientific article published on December 2012

AUC-Maximizing Ensembles through Metalearning.

scientific article

Accounting for heterogeneous treatment effects in the FDA approval process

scientific article published in January 2012

Adaptive pair-matching in randomized trials with unbiased and efficient effect estimation.

scientific article

Adaptive pre-specification in randomized trials with and without pair-matching

scientific article

Adaptive sequential surveillance with network and temporal dependence

scholarly article

Addressing Missing Data in Clinical Trials ⬇️

scientific article published on July 19, 2011

An Application of Collaborative Targeted Maximum Likelihood Estimation in Causal Inference and Genomics ⬇️

scientific article published on May 17, 2010

An application of model-fitting procedures for marginal structural models

scientific article published on 13 July 2005

An application of targeted maximum likelihood estimation to the meta-analysis of safety data

scientific article

An omnibus non-parametric test of equality in distribution for unknown functions

scientific article published on 02 November 2018

Analysis of longitudinal marginal structural models.

scientific article published in July 2004

Analysis of the effect of occupational exposure to asbestos based on threshold regression modeling of case-control data

scientific article

Analyzing Direct Effects in Randomized Trials with Secondary Interventions: An Application to HIV Prevention Trials

scientific article

Analyzing sequentially randomized trials based on causal effect models for realistic individualized treatment rules

scientific article published in August 2008

Antihypertensive Medication Use and Change in Kidney Function in Elderly Adults: A Marginal Structural Model Analysis ⬇️

scientific article published on September 8, 2011

Application of targeted maximum likelihood estimation technique to assess the impact of prenatal exposure to nitrogen dioxide and ozone on stillbirth in a California cohort study ⬇️

scholarly article

Assessing the causal effect of policies: an example using stochastic interventions

scientific article published on 19 November 2013

Assessing the effectiveness of antiretroviral adherence interventions. Using marginal structural models to replicate the findings of randomized controlled trials

scientific article published in December 2006

Association of Implementation of a Universal Testing and Treatment Intervention With HIV Diagnosis, Receipt of Antiretroviral Therapy, and Viral Suppression in East Africa

scientific article published on June 2017

Assumption Trade-Offs When Choosing Identification Strategies for Pre-Post Treatment Effect Estimation: An Illustration of a Community-Based Intervention in Madagascar

scientific article published on March 2015

Asymptotic optimality of likelihood-based cross-validation

scientific article published on 22 March 2004

Augmentation procedures for control of the generalized family-wise error rate and tail probabilities for the proportion of false positives.

scientific article published on 15 June 2004

Balancing Score Adjusted Targeted Minimum Loss-based Estimation

scientific article

Big Data, Small Sample

scientific article published on 20 May 2017

Biomarker discovery using targeted maximum-likelihood estimation: application to the treatment of antiretroviral-resistant HIV infection

scientific article

Causal Inference for a Population of Causally Connected Units

scientific article

Causal effect models for realistic individualized treatment and intention to treat rules.

scientific article published in January 2007

Causal inference in epidemiological studies with strong confounding ⬇️

scientific article published on February 23, 2012

Causal inference in longitudinal studies with history-restricted marginal structural models ⬇️

scientific article published on January 1, 2007

Causal inference when counterfactuals depend on the proportion of all subjects exposed

scientific article published on 03 April 2019

Causal models and learning from data: integrating causal modeling and statistical estimation

scientific article

Collaborative Targeted Maximum Likelihood for Time to Event Data ⬇️

scientific article published on January 1, 2010

Collaborative double robust targeted maximum likelihood estimation

scientific article published on 17 May 2010

Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries

scientific article published on 29 June 2016

Collaborative-controlled LASSO for constructing propensity score-based estimators in high-dimensional data.

scientific article published in January 2017

Colon cancer survival with herbal medicine and vitamins combined with standard therapy in a whole-systems approach: ten-year follow-up data analyzed with marginal structural models and propensity score methods.

scientific article

Comment on 'Entropy Learning for Dynamic Treatment Regimes' by Binyan Jiang, Rui Song, et al.

scholarly article

Comparison of targeted maximum likelihood and shrinkage estimators of parameters in gene networks

scientific article published on 25 September 2012

Complier Stochastic Direct Effects: Identification and Robust Estimation ⬇️

scholarly article

Computationally efficient confidence intervals for cross-validated area under the ROC curve estimates

scientific article published on January 2015

Confidence intervals for the population mean tailored to small sample sizes, with applications to survey sampling

scientific article published on 7 January 2009

Consistent causal effect estimation under dual misspecification and implications for confounder selection procedures ⬇️

scientific article published on February 23, 2012

Constrained binary classification using ensemble learning: an application to cost-efficient targeted PrEP strategies.

scientific article

Cravings as a mediator and moderator of drinking outcomes in the COMBINE study

scientific article published on 4 June 2013

Cross-Validated Bagged Learning

scientific article

Cross-Validated Loss-Based Covariance Matrix Estimator Selection in High Dimensions

scientific article published in 2022

Cross-validated bagged prediction of survival.

scientific article published in January 2006

DISCUSSION OF: TREELETS-AN ADAPTIVE MULTI-SCALE BASIS FOR SPARSE UNORDERED DATA.

scientific article

Data-adaptive longitudinal model selection in causal inference with collaborative targeted minimum loss-based estimation

scientific article published on 06 November 2019

Data-adaptive test statistics for microarray data

scientific article

Deletion/substitution/addition algorithm in learning with applications in genomics

scientific article

Diagnosing and responding to violations in the positivity assumption ⬇️

scientific article published on October 28, 2010

Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial

scientific article published on July 2007

Dimension reduction with gene expression data using targeted variable importance measurement

scientific article

Direct Effect Models ⬇️

scientific article published on January 1, 2008

Discussion of "Deductive derivation and turing-computerization of semiparametric efficient estimation" by Frangakis et al.

scientific article

Discussion of Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer, by Wang et al. 2012.

scientific article published on April 2012

Discussion of Identification, Estimation and Approximation of Risk under Interventions that Depend on the Natural Value of Treatment Using Observational Data, by Jessica Young, Miguel Hernán, and James Robins

scientific article

Double Robust Efficient Estimators of Longitudinal Treatment Effects: Comparative Performance in Simulations and a Case Study

scientific article published on 26 February 2019

Doubly Robust and Efficient Estimation of Marginal Structural Models for the Hazard Function.

scientific article

Doubly robust inference for targeted minimum loss-based estimation in randomized trials with missing outcome data

scientific article

Drug development strategies for salvage therapy: conflicts and solutions

scientific article published in November 2006

EFFECT OF BREASTFEEDING ON GASTROINTESTINAL INFECTION IN INFANTS: A TARGETED MAXIMUM LIKELIHOOD APPROACH FOR CLUSTERED LONGITUDINAL DATA. ⬇️

scientific article

Early prediction of median survival among a large AIDS surveillance cohort

scientific article

Effect Modification by Sex and Baseline CD4+Cell Count Among Adults Receiving Combination Antiretroviral Therapy in Botswana: Results from a Clinical Trial ⬇️

scientific article published on March 23, 2012

Effects of body composition and leisure-time physical activity on transitions in physical functioning in the elderly

scientific article

Efficient nonparametric inference on the effects of stochastic interventions under two-phase sampling, with applications to vaccine efficacy trials

scientific article published on 19 September 2020

Empirical Bayes and resampling based multiple testing procedure controlling tail probability of the proportion of false positives

scientific article published on 7 October 2005

Empirical efficiency maximization: improved locally efficient covariate adjustment in randomized experiments and survival analysis

scientific article published in January 2008

Entering the Era of Data Science: Targeted Learning and the Integration of Statistics and Computational Data Analysis

scholarly article by Mark J. van der Laan & Richard J. C. M. Starmans published 2014 in Advances in statistics

Estimating Effects with Rare Outcomes and High Dimensional Covariates: Knowledge is Power.

scientific article published on 24 May 2016

Estimating the Effect of a Community-Based Intervention with Two Communities

scientific article published on May 2013

Estimation Based on Case-Control Designs with Known Prevalence Probability ⬇️

scientific article published on January 1, 2008

Estimation of a non-parametric variable importance measure of a continuous exposure

scientific article published on January 2012

Estimation of direct causal effects

scientific article

Estimation of the optimal surrogate based on a randomized trial

scientific article published on 27 April 2018

Evaluating the Impact of a HIV Low-Risk Express Care Task-Shifting Program: A Case Study of the Targeted Learning Roadmap

scientific article

Evaluating the impact of treating the optimal subgroup

scientific article published on January 2017

Expert-augmented machine learning

scientific article published on 18 February 2020

Explaining differential effects of medication for opioid use disorder using a novel approach incorporating mediating variables

scientific article published on 19 December 2020

Exploiting non-systematic covariate monitoring to broaden the scope of evidence about the causal effects of adaptive treatment strategies

scientific article published on 15 April 2020

Exploratory and confirmatory gene expression profiling of mac1Delta.

scientific article

Far from MCAR: Obtaining population-level estimates of HIV viral suppression

scientific article published on 20 May 2020

Finding hotspots: development of an adaptive spatial sampling approach

scientific article published on 02 July 2020

Finding quantitative trait loci genes with collaborative targeted maximum likelihood learning ⬇️

scientific article published on July 1, 2011

HIV Testing and Treatment with the Use of a Community Health Approach in Rural Africa

scientific article published on 01 July 2019

Highly Adaptive Lasso (HAL)

History-adjusted marginal structural models for estimating time-varying effect modification

scientific article published on 17 September 2007

Identification and efficient estimation of the natural direct effect among the untreated

scientific article published on 23 April 2013

Identification of regulatory elements using a feature selection method.

scientific article published in September 2002

Identification of the joint effect of a dynamic treatment intervention and a stochastic monitoring intervention under the no direct effect assumption

scientific article

Improving propensity score estimators' robustness to model misspecification using super learner

scientific article

Individualized treatment rules: generating candidate clinical trials

scientific article published on November 2007

Influenza vaccination and mortality: differentiating vaccine effects from bias

scientific article published on 22 July 2009

Issues of processing and multiple testing of SELDI-TOF MS proteomic data

scientific article

Leisure-time physical activity and all-cause mortality in an elderly cohort

scientific article

Long-term consequences of the delay between virologic failure of highly active antiretroviral therapy and regimen modification

scientific article published on October 2008

Longitudinal Mediation Analysis with Time-varying Mediators and Exposures, with Application to Survival Outcomes

scientific article published on 23 June 2017

Lung cancer survival with herbal medicine and vitamins in a whole-systems approach: ten-year follow-up data analyzed with marginal structural models and propensity score methods

scientific article

Machine learning to identify persons at high-risk of HIV acquisition in rural Kenya and Uganda

scientific article published on 07 November 2019

Marginal Structural Models with Counterfactual Effect Modifiers

scientific article published on 08 June 2018

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels

scientific article

Modeling the impact of hepatitis C viral clearance on end-stage liver disease in an HIV co-infected cohort with targeted maximum likelihood estimation

scientific article

Modeling treatment effects on binary outcomes with grouped-treatment variables and individual covariates

scientific article published in October 2002

Modified FDR controlling procedure for multi-stage analyses

scientific article

Mortality prediction in intensive care units with the Super ICU Learner Algorithm (SICULA): a population-based study

scientific article

Multiple testing and data adaptive regression: an application to HIV-1 sequence data

scientific article

Multiple testing methods for ChIP-Chip high density oligonucleotide array data

scientific article

Multiple testing. Part I. Single-step procedures for control of general type I error rates

scientific article published on 9 June 2004

Multiple testing. Part II. Step-down procedures for control of the family-wise error rate

scientific article published on 14 June 2004

Nonlinearity in demographic and behavioral determinants of morbidity

scientific article

Nonparametric bootstrap inference for the targeted highly adaptive least absolute shrinkage and selection operator (LASSO) estimator

scientific article published on 10 August 2020

Occupational exposure to PM2.5 and incidence of ischemic heart disease: longitudinal targeted minimum loss-based estimation

journal article published in 2015

On adaptive propensity score truncation in causal inference

scientific article published on 11 July 2018

One-Step Targeted Minimum Loss-based Estimation Based on Universal Least Favorable One-Dimensional Submodels

scientific article published in May 2016

One-step targeted maximum likelihood estimation for time-to-event outcomes

scientific article published on 15 November 2019

Online Super Learning

article published in 2018

Online cross-validation-based ensemble learning.

scientific article published on 4 May 2017

Optimal Individualized Treatments in Resource-Limited Settings.

scientific article published in May 2016

Optimal Spatial Prediction Using Ensemble Machine Learning

scientific article published on 01 May 2016

Optimizing matching and analysis combinations for estimating causal effects

scientific article published on 16 March 2016

Parametric-rate inference for one-sided differentiable parameters

scientific article published on 28 February 2017

Petersen et al. Respond to "Effect Modification by Time-varying Covariates" ⬇️

scientific article published on November 1, 2007

Pillbox organizers are associated with improved adherence to HIV antiretroviral therapy and viral suppression: a marginal structural model analysis

scientific article published on 20 August 2007

Population Intervention Causal Effects Based on Stochastic Interventions ⬇️

scientific article published on October 6, 2011

Propensity score prediction for electronic healthcare databases using Super Learner and High-dimensional Propensity Score Methods

scientific article published on 22 February 2019

Quantile-function based null distribution in resampling based multiple testing.

scientific article published on 21 May 2006

Rachael V. Phillips and Mark J. van der Laan’s contribution to the Discussion of ‘Assumption‐lean inference for generalised linear model parameters’ by Vansteelandt and Dukes

scientific article published in 2022

Racial/Ethnic Differences in the Role of Childhood Adversities for Mental Disorders Among a Nationally Representative Sample of Adolescents

scientific article

Regulatory motif finding by logic regression

scientific article published on 27 May 2004

Rejoinder to Tan

scientific article published on 01 January 2008

Repeated measures semiparametric regression using targeted maximum likelihood methodology with application to transcription factor activity discovery

scientific article published on 6 January 2011

Resampling-based empirical Bayes multiple testing procedures for controlling generalized tail probability and expected value error rates: focus on the false discovery rate and simulation study

scientific article published on October 2008

Robust estimation of encouragement-design intervention effects transported across sites

scientific article published on 31 October 2016

Robust inference on the average treatment effect using the outcome highly adaptive lasso

scientific article published on 30 October 2019

Robust variance estimation and inference for causal effect estimation

scientific article published in 2023

Rose and van der Laan respond to "Some advantages of the relative excess risk due to interaction".

scientific article published on 31 January 2014

STATISTICAL INFERENCE FOR THE MEAN OUTCOME UNDER A POSSIBLY NON-UNIQUE OPTIMAL TREATMENT STRATEGY ⬇️

scientific article published on 17 March 2016

Scalable collaborative targeted learning for high-dimensional data

scientific article published in January 2017

Second-Order Inference for the Mean of a Variable Missing at Random

scientific article published on 01 May 2016

Selecting Optimal Subgroups for Treatment Using Many Covariates

scientific article published on 01 May 2019

Semi-Parametric Estimation and Inference for the Mean Outcome of the Single Time-Point Intervention in a Causally Connected Population

scientific article published on 29 November 2016

Sensitivity analysis for causal inference under unmeasured confounding and measurement error problems

article

Simple optimal weighting of cases and controls in case-control studies.

scientific article published on 29 September 2008

Simple, efficient estimators of treatment effects in randomized trials using generalized linear models to leverage baseline variables.

scientific article published in April 2010

Smoking Is Associated with Higher Disease Activity in Rheumatoid Arthritis: A Longitudinal Study Controlling for Time-varying Covariates.

scientific article published in December 2018

Special Issue on Data-Adaptive Statistical Inference.

scientific article

Statistical Inference for Data Adaptive Target Parameters.

scientific article published in May 2016

Statistical Issues and Limitations in Personalized Medicine Research with Clinical Trials ⬇️

scientific article published on July 20, 2012

Statistical estimation of parameters in a disease transmission model: analysis of a Cryptosporidium outbreak.

scientific article

Statistical inference for simultaneous clustering of gene expression data

scientific article

Statistical learning of origin-specific statically optimal individualized treatment rules.

scientific article

Statistical methods for analyzing sequentially randomized trials

scientific article published on 30 October 2007

Subsemble: an ensemble method for combining subset-specific algorithm fits

scientific article

Super Learner Analysis of Electronic Adherence Data Improves Viral Prediction and May Provide Strategies for Selective HIV RNA Monitoring

scientific article

Super Learner Based Conditional Density Estimation with Application to Marginal Structural Models ⬇️

scientific article published on October 3, 2011

Super learner

scientific article published on 16 September 2007

Super learning: an application to the prediction of HIV-1 drug resistance

scientific article published on 23 February 2007

Super-Learning of an Optimal Dynamic Treatment Rule

scientific article published on 01 May 2016

Supervised detection of conserved motifs in DNA sequences with cosmo

scientific article published on 23 February 2007

Supervised detection of regulatory motifs in DNA sequences

scientific article published on 25 August 2003

Supervised distance matrices

scientific article

Survival ensembles.

scientific article published on 12 December 2005

TARGETED SEQUENTIAL DESIGN FOR TARGETED LEARNING INFERENCE OF THE OPTIMAL TREATMENT RULE AND ITS MEAN REWARD.

scientific article published on 15 December 2017

Targeted Data Adaptive Estimation of the Causal Dose–Response Curve

scientific article published in 2013

Targeted Learning of the Mean Outcome under an Optimal Dynamic Treatment Rule

scientific article published in March 2015

Targeted Maximum Likelihood Estimation for Dynamic Treatment Regimes in Sequentially Randomized Controlled Trials ⬇️

scientific article published on June 22, 2012

Targeted Maximum Likelihood Estimation for Dynamic and Static Longitudinal Marginal Structural Working Models.

scientific article

Targeted Maximum Likelihood Estimation of Natural Direct Effects ⬇️

scientific article published on January 6, 2012

Targeted Minimum Loss Based Estimation of Causal Effects of Multiple Time Point Interventions ⬇️

scientific article published on January 1, 2012

Targeted Minimum Loss Based Estimation of a Causal Effect on an Outcome with Known Conditional Bounds ⬇️

scientific article published on July 25, 2012

Targeted Minimum Loss Based Estimator that Outperforms a given Estimator ⬇️

scientific article published on May 18, 2012

Targeted Minimum Loss-Based Estimation

Targeted Minimum Loss-Based Estimation of Causal Effects in Right-Censored Survival Data with Time-Dependent Covariates: Warfarin, Stroke, and Death in Atrial Fibrillation

scientific article published in 2013

Targeted estimation and inference for the sample average treatment effect in trials with and without pair-matching.

scientific article published on 18 April 2016

Targeted estimation of binary variable importance measures with interval-censored outcomes

scientific article published in January 2014

Targeted estimation of nuisance parameters to obtain valid statistical inference.

scientific article published in January 2014

Targeted learning in real-world comparative effectiveness research with time-varying interventions

scientific article published on 17 February 2014

Targeted learning with daily EHR data

scientific article published on 25 April 2019

Targeted maximum likelihood based causal inference: Part I.

scientific article published in January 2010

Targeted maximum likelihood based causal inference: Part II.

scientific article published on 22 February 2010

Targeted maximum likelihood estimation for prediction calibration.

scientific article published on 31 October 2012

Targeted maximum likelihood estimation in safety analysis

scientific article published on August 2013

Targeted maximum likelihood estimation of effect modification parameters in survival analysis

scientific article published on 30 March 2011

Targeted maximum likelihood estimation of the parameter of a marginal structural model

scientific article published on 15 April 2010

Testing the Relative Performance of Data Adaptive Prediction Algorithms: A Generalized Test of Conditional Risk Differences.

scientific article

The Authors Respond

scientific article published on 01 May 2020

The Authors Respond

scientific article published on 01 July 2020

The Highly Adaptive Lasso Estimator

scientific article published on 26 December 2016

The Relative Performance of Ensemble Methods with Deep Convolutional Neural Networks for Image Classification

scientific article published on 26 February 2018

The Relative Performance of Targeted Maximum Likelihood Estimators ⬇️

scientific article published on August 17, 2011

The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapy

scientific article

Toward computerized efficient estimation in infinite-dimensional models

scientific article published on 13 September 2018

Transporting stochastic direct and indirect effects to new populations

scientific article published on 11 April 2020

Use of a machine learning framework to predict substance use disorder treatment success

scientific article

Using Super Learner Prediction Modeling to Improve High-dimensional Propensity Score Estimation

scientific article

Using regression models to analyze randomized trials: asymptotically valid hypothesis tests despite incorrectly specified models

scientific article published on 04 February 2009

Validation of Predictive Models in Inflammatory Bowel Diseases

scientific article published on 11 November 2020

Virologic efficacy of boosted double versus boosted single protease inhibitor therapy

scientific article published on July 2007

Why match? Investigating matched case-control study designs with causal effect estimation

scientific article published on 06 January 2009

cvCovEst: Cross-validated covariance matrix estimator selection and evaluation in R

scientific article published on 26 July 2021

hal9001: Scalable highly adaptive lasso regression in R

scientific article published on 26 September 2020

methyvim: Targeted, robust, and model-free differential methylation analysis in R

scholarly article

partDSA: deletion/substitution/addition algorithm for partitioning the covariate space in prediction

scientific article

simcausal R Package: Conducting Transparent and Reproducible Simulation Studies of Causal Effect Estimation with Complex Longitudinal Data.

scientific article published on 16 October 2017

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