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List of works by Napoleone Ferrara

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain

scientific article

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain.

scientific article published in August 2015

A direct and melanopsin-dependent fetal light response regulates mouse eye development

scientific article published on 16 January 2013

A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life

scientific article published on 30 March 2010

ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo

scientific article

An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

scientific article published on 4 August 2013

Angiogenesis-Dependent and Independent Phases of Intimal Hyperplasia

scientific article published on 11 October 2004

Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

scientific article

Angiogenic inhibitors: a new therapeutic strategy in oncology

scientific article

Anti-angiogenic drugs to treat human disease: an interview with Napoleone Ferrara by Kristin H. Kain

scientific article published in July 2009

Antiangiogenesis to treat cancer and intraocular neovascular disorders

scientific article published on 29 January 2007

Antiangiogenic therapy for cancer: an update

scientific article published on 01 November 2007

Anti‐VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models ⬇️

scientific article published on June 28, 2012

Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature

scientific article (publication date: 29 July 2010)

Autocrine VEGF signaling is required for vascular homeostasis

scientific article

Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy

scientific article

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

scientific article (publication date: 3 June 2004)

Binding to the extracellular matrix and proteolytic processing: two key mechanisms regulating vascular endothelial growth factor action

scientific article published on March 2010

Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1.

scientific article published in January 2008

Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization

scholarly article

Bv8 regulates myeloid-cell-dependent tumour angiogenesis

scientific article published on December 2007

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

scientific article published on 10 May 2012

Chapter 6. Mouse models to investigate anti-cancer effects of VEGF inhibitors

scientific article published in January 2008

Characterization and regulation of bv8 in human blood cells

scientific article published on 31 March 2009

Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells

scientific article published on 20 December 2001

Commentary on "Humanization of an Anti-VEGF Monoclonal Antibody for the Therapy of Solid Tumors and Other Disorders".

scientific article published in September 2016

Comparing protein VEGF inhibitors: In vitro biological studies ⬇️

scientific article published on April 8, 2011

Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A.

scientific article published on 16 September 2014

Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation

scientific article

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Corneal avascularity is due to soluble VEGF receptor-1

scientific article (publication date: 26 October 2006)

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

scientific article published in October 2003

Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.

scientific article published on 18 December 2013

Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

scientific article

Development and preclinical characterization of a humanized antibody targeting CXCL12

scientific article

Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration

scientific article published on October 2006

Developmental and pathological angiogenesis ⬇️

scientific article published on July 13, 2011

Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors ⬇️

scientific article published on July 3, 2012

Differential expression of the angiogenic factor genes vascular endothelial growth factor (VEGF) and endocrine gland-derived VEGF in normal and polycystic human ovaries

scientific article published on June 2003

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

scientific article published on 17 July 2017

Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells

scientific article (publication date: July 2004)

EG-VEGF and Bv8. a novel family of tissue-selective mediators of angiogenesis, endothelial phenotype, and function

scientific article published on October 2003

EG-VEGF and Bv8: a novel family of tissue-restricted angiogenic factors

scientific article published on March 2004

EG-VEGF and the concept of tissue-specific angiogenic growth factors

scientific article

EG-VEGF: a novel mediator of endocrine-specific angiogenesis, endothelial phenotype, and function

scientific article published on April 2004

Effects of an anti-VEGF-A monoclonal antibody on laser-induced choroidal neovascularization in mice: optimizing methods to quantify vascular changes.

scientific article

Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors

scientific article published on 18 February 2010

Endocrine gland vascular endothelial growth factor (EG-VEGF) and the hypothesis of tissue-specific regulation of angiogenesis

scientific article published on 01 November 2002

Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis

scientific article

Endothelial cells regulate neural crest and second heart field morphogenesis

scientific article published on 4 July 2014

Endothelium-microenvironment interactions in the developing embryo and in the adult

scientific article published on February 2007

Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis

scientific article published on 3 May 2007

Evidence for Pro-angiogenic Functions of VEGF-Ax

scientific article published in September 2016

Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

scientific article

Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library

scientific article

Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.

scientific article published on 18 February 2010

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

scholarly article

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

article published in 2003

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

scientific article

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes ⬇️

scientific article published on November 16, 2010

Human endocrine gland-derived vascular endothelial growth factor: expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis

scientific article published in August 2004

Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies.

scientific article published on 17 May 2013

Imaging tumor angiogenesis

scientific article published in October 2006

Induction of Bv8 expression by granulocyte colony-stimulating factor in CD11b+Gr1+ cells: key role of Stat3 signaling.

scientific article

Inhibiting the response to VEGF in diabetes.

scientific article

Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice

scholarly article

Interaction between bevacizumab and murine VEGF-A: a reassessment

scientific article

Interleukin-22 promotes tumor angiogenesis

scientific article published on 11 December 2018

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation ⬇️

scientific article published on August 13, 2012

Introduction by the Guest Editors: Bevacizumab

scientific article published on 01 July 2018

Local guidance of emerging vessel sprouts requires soluble Flt-1

scientific journal article

Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

scientific article published in November 2004

Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair

scientific article

Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies

scholarly article

Mouse endocrine gland-derived vascular endothelial growth factor: a distinct expression pattern from its human ortholog suggests different roles as a regulator of organ-specific angiogenesis

scientific journal article

Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response

scientific article

Multiple Effects of Angiopoietin-2 Blockade on Tumors ⬇️

scientific article published on April 12, 2011

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.

scientific article published on 27 April 2016

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.

scientific article published in August 2016

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment

scientific article published on 25 March 2013

Outer retinal tubulations response to anti-VEGF treatment.

scientific article published on 30 September 2015

PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment

scientific article

Paracrine VEGF/VE-cadherin action on ovarian cancer permeability

scientific article published in November 2006

Pathways mediating VEGF-independent tumor angiogenesis

scientific article published on 11 December 2009

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1.

scientific article published on 17 November 2017

Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback.

scientific article published on 26 January 2005

Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies.

scientific article published on February 2005

Phosphoproteomic analysis implicates the mTORC2-FoxO1 axis in VEGF signaling and feedback activation of receptor tyrosine kinases

scientific article published on 16 April 2013

Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.

scientific article published on 18 June 2013

PlGF blockade does not inhibit angiogenesis during primary tumor growth

scientific article published on April 2010

Platelet-derived growth factor C promotes revascularization in ischemic limbs of diabetic mice

scientific article published on 13 July 2013

Quantification of viable tumor microvascular characteristics by multispectral analysis.

scientific article published in July 2008

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging

scientific article

Redundant roles of VEGF-B and PlGF during selective VEGF-A blockade in mice.

scientific article published on 27 September 2005

Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells

scientific article published on July 2008

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells

scientific article published on 29 May 2011

Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression

scholarly article

Role of VEGF-A in vascularization of pancreatic islets

scientific article

Role of myeloid cells in tumor angiogenesis and growth

scientific article published on 07 July 2008

Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis

scientific article published on May 2010

Role of the microenvironment in tumor growth and in refractoriness/resistance to anti-angiogenic therapies

scientific article published on 23 October 2008

Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications

scientific article

S1P1 inhibits sprouting angiogenesis during vascular development

scientific article published on 5 September 2012

Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.

scientific article

Stromal cell-derived factor-1/CXCL12 contributes to MMTV-Wnt1 tumor growth involving Gr1+CD11b+ cells

scientific article (publication date: 19 January 2010)

Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer

scientific article published on 19 August 2020

Targeting VEGF-A to treat cancer and age-related macular degeneration

scientific article published on January 2007

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma

scientific article published on February 2013

Targeting the tumor microenvironment with SRC kinase inhibition

scientific article published on 26 January 2010

Targeting the tumour vasculature: insights from physiological angiogenesis

scientific article published on July 2010

The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis

scientific article published on February 2016

The biology of VEGF and its receptors

scientific article (publication date: June 2003)

The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells

scientific article

The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf.

scientific article published on 4 March 2009

The function of VEGF-A in lens development: formation of the hyaloid capillary network and protection against transient nuclear cataracts.

scientific article published on 20 August 2008

The heart endocardium is derived from vascular endothelial progenitors ⬇️

scientific article published on November 1, 2011

The hypoxic response of tumors is dependent on their microenvironment.

scientific article

The molecular basis of vascular lumen formation in the developing mouse aorta

scientific journal article

The role of VEGF in normal and neoplastic hematopoiesis

scientific article

The role of VEGF in the regulation of physiological and pathological angiogenesis

scientific article

The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation

scientific article published on March 2006

Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas

scientific article published on 29 July 2020

Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies

scientific article published on December 2009

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

scientific article

Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma

scientific article published on May 2006

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway.

scientific article

VEGF and Intraocular Neovascularization: From Discovery to Therapy

scientific article

VEGF and the quest for tumour angiogenesis factors

scientific article

VEGF as a therapeutic target in cancer

scientific article

VEGF in Signaling and Disease: Beyond Discovery and Development

scientific article published on 01 March 2019

VEGF inhibition and renal thrombotic microangiopathy

scientific article

VEGF inhibition: insights from preclinical and clinical studies

scientific article published on 03 September 2008

VEGF modulates synaptic activity in the developing spinal cord.

scientific article published on 24 May 2014

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

scientific article published in June 2002

VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus

scientific article published in January 2002

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

scientific article published in March 2002

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.

scientific article published on 02 August 2013

VEGF-A: a critical regulator of blood vessel growth

scientific article published on December 2009

VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis

scientific article

VEGFA is necessary for chondrocyte survival during bone development

scientific journal article

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease ⬇️

scientific article published on September 29, 2012

Vascular endothelial growth factor

scientific article published on 22 January 2009

Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-C(deltaNdeltaC)- and VEGF-A-induced angiogenesis in vitro

scientific journal article

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival

scientific article published on 25 January 2006

Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy ⬇️

scientific article published on October 1, 2010

Vascular endothelial growth factor as a target for anticancer therapy

scientific article published on January 2004

Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature

scientific journal article

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function

scientific journal article

Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer

scientific article published on November 2002

Vascular endothelial growth factor signaling pathways: therapeutic perspective

scientific article published on September 2006

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover

scientific article

Vascular endothelial growth factor: basic science and clinical progress

scientific article

Vascular patterning regulates interdigital cell death by a ROS-mediated mechanism

scientific article published on 23 January 2015

Vascular targeting via caveolae

scientific article published on 01 April 2007

Vegf regulates embryonic erythroid development through Gata1 modulation

scientific article published on 16 June 2010

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