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List of works by Judith Clements

3D Cultures of prostate cancer cells cultured in a novel high-throughput culture platform are more resistant to chemotherapeutics compared to cells cultured in monolayer

scientific article

5 Cellular Model Systems to Study the Tumor Biological Role of Kallikrein-related Peptidases in Ovarian and Prostate Cancer

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns

scientific article published on 16 October 2018

A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

scientific article

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

scientific article

A Plasma Biomarker Panel of Four MicroRNAs for the Diagnosis of Prostate Cancer.

scientific article

A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread

scientific article

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

scientific article

A computational analysis of the genetic and transcript diversity at the kallikrein locus

scientific article published on 11 June 2016

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer

scientific article

A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.

scientific article

A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone

scientific article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness

scientific article published on 4 December 2017

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus

scientific article published on March 2008

A replication study examining novel common single nucleotide polymorphisms identified through a prostate cancer genome-wide association study in a Japanese population

scientific article published on 15 November 2011

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

scientific article published on 20 April 2010

ACTIVATION OF THE KALLIKREIN KININ SYSTEM IN INTERSTITIAL CYSTITIS

scientific article published on 01 July 1999

Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases.

scientific article published on September 2014

Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop

scientific article published on 17 December 2015

Adrenocorticotropin, β-Endorphin, and β-Mipotropin in Normal Thyroid and Lung: Possible Implications for Ectopic Hormone Secretion

scientific article published on 01 December 1982

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk

scientific article published on 06 August 2020

Analysis of androgen and anti-androgen regulation of KLK-related peptidase 2, 3, and 4 alternative transcripts in prostate cancer

scientific article published on September 2014

Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group

scientific article

Association Analysis of a Microsatellite Repeat in the Gene With Prostate Cancer Risk, Aggressiveness and Survival

article

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scientific article published on 11 June 2018

Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data

scientific article

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis

scholarly article

Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population.

scientific article published on 28 February 2015

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Beyond the biomarker role: prostate-specific antigen (PSA) in the prostate cancer microenvironment

scientific article published on 01 September 2019

Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells

scientific article published on 14 August 2010

Bone and prostate cancer cell interactions in metastatic prostate cancer

scientific article published on 13 December 2006

Breast cancer cells induce osteolytic bone lesions in vivo through a reduction in osteoblast activity in mice

scientific article

Can tissue engineering concepts advance tumor biology research?

scientific article published on 06 January 2010

Candidate gene association studies: a comprehensive guide to useful in silico tools

scientific article

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors

scientific article (publication date: September 2001)

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

scientific article published on 23 October 2018

Coffee contains potent opiate receptor binding activity

scientific article published in Nature

Combined expression of KLK4, KLK5, KLK6, and KLK7 by ovarian cancer cells leads to decreased adhesion and paclitaxel-induced chemoresistance

scientific article published on 8 September 2012

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness

article

Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies

scientific article published on July 2010

Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms.

scientific article published on December 2005

Concomitant dopaminergic and glucocorticoid control of pituitary proopiomelanocortin messenger ribonucleic acid and beta-endorphin levels

scientific article

Correction: 3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer

scientific article published on 22 April 2015

Correction: Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment.

scientific article published on 17 January 2013

Correlation of the expression of human kallikrein-related peptidases 4 and 7 with the prognosis in oral squamous cell carcinoma

scientific article published on April 2011

DC therapy for prostate cancer

scientific article published in January 2004

Delineating breast cancer cell interactions with engineered bone microenvironments

scientific article published on June 2013

Determining Protease Substrates Within a Complex Protein Background Using the PROtein TOpography and Migration Analysis Platform (PROTOMAP).

scientific article published in January 2017

Development of Anti-hLH Antibodies after Therapy with Posterior Pituitary Extract*

scientific article published on July 1, 1978

Differential splicing of KLK5 and KLK7 in epithelial ovarian cancer produces novel variants with potential as cancer biomarkers ⬇️

scientific article (publication date: May 2003)

Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer

scientific article published in January 2009

EXPRESSION OF THE PROLACTIN GENE IN HUMAN DECIDUA-CHORION

article

Elevated plasma levels of pro-opiomelanocortin-derived peptides in sheep following hypothalamo-pituitary disconnection.

scientific article published in January 1986

Emergence of MicroRNAs as Key Players in Cancer Cell Metabolism

scientific article published on 17 May 2019

Engineered microenvironments provide new insights into ovarian and prostate cancer progression and drug responses

scientific article

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment

scientific article published on 25 April 2019

Enter the Dragon: The Dynamic and Multifunctional Evolution of Anguimorpha Lizard Venoms

scientific article published on 6 August 2017

Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

scientific article published on November 2007

Epithelial-mesenchymal transition in prostate cancer and the potential role of kallikrein serine proteases

scientific article published on January 2007

Erratum to: Fusion transcript loci share many genomic features with non-fusion loci.

scientific article published on 3 June 2016

Estrogen regulation of kallikrein gene expression in the rat anterior pituitary

scientific article published in July 1986

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors

scientific article published on 19 February 2016

Expression analysis of ?-catenin and prostate-specific membrane antigen: Their potential as diagnostic markers for prostate cancer

scientific article published on 01 July 2002

Expression of PSA-RP2, an alternatively spliced variant from the PSA gene, is increased in prostate cancer tissues but the protein is not secreted from prostate cancer cells.

scientific article

Expression of PTRF in PC-3 Cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways

scientific article

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

scientific article published on 27 March 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

scientific article

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

scientific article

Fusion transcript loci share many genomic features with non-fusion loci

scientific article published in December 2015

Gamma-Tocotrienol Induces Apoptosis in Prostate Cancer Cells by Targeting the Ang-1/Tie-2 Signalling Pathway ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Genetic association of the KLK4 locus with risk of prostate cancer

scientific article

Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases

scientific article published on December 2012

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association study of prostate cancer-specific survival

scientific article published on 25 August 2015

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Glandular kallikreins and prostate-specific antigen are expressed in the human endometrium

scientific article published on 01 June 1994

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

scientific article

Glucocorticoid Regulation of Proopiomelanocortin Gene Expression in the Pituitary Gland of Hypothalamopituitary Intact and Hypothalamopituitary Disconnected Sheep

article

Gonadal steroids and anterior lobe dynorphin in the male rat

scientific article published on 01 February 1989

Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach ⬇️

scientific article published on March 1, 2013

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

scientific article

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

article by Artitaya Lophatananon et al published 20 March 2018 in British Journal of Cancer

Highlight: proteolytic networks across cellular boundaries.

scientific article

Highlight: remodelling the KLK landscape down under

scientific article published on 01 December 2016

Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients.

scientific article published on 27 August 2011

Humanised xenograft models of bone metastasis revisited: novel insights into species-specific mechanisms of cancer cell osteotropism

scientific article published on June 2013

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone

scientific article published on 13 November 2018

Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.

scientific article

Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.

scientific article published on February 2005

IMMUNOREACTIVE ?-ENDORPHIN LEVELS IN PLASMA AND PITUITARY TISSUE FROM GENETICALLY HYPERTENSIVE AND NORMOTENSIVE RATS

scientific article published on 01 September 1981

INSULIN HYPOGLYCAEMIA AND CHOLINERGIC BLOCKADE: RESPONSE OF PLASMA IMMUNOREACTIVE β-ENDORPHIN

scientific article published on 01 November 1983

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle.

scientific article

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

scientific article

Identification of evidence-based biospecimen quality-control tools: a report of the International Society for Biological and Environmental Repositories (ISBER) Biospecimen Science Working Group

scientific article

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

scientific article

Immuno- and bioactive inhibin and inhibin alpha-subunit expression in rat Leydig cell cultures

scientific article published in September 1989

In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.

scientific article

Inactive free : total prostate specific antigen ratios in ejaculate from men with suspected and known prostate cancer, compared with young control men

scientific article published on 01 September 2000

Inhibin a-subunit gene expression in the ovaries of immature female rats is stimulated by pregnant mare serum gonadotrophin

article

Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome

scientific article published on 31 January 2019

Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model

scientific article published on July 2010

KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer

scientific article published on 24 November 2020

Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE.

scientific article published on May 2001

Kallikrein 4 is a potential mediator of cellular interactions between cancer cells and osteoblasts in metastatic prostate cancer

scientific article published on March 2007

Kallikrein gene expression in estrogen-induced pituitary tumors

article

Kallikrein gene expression in the gonadotrophin-stimulated rat ovary

scientific article

Kallikrein gene expression in the rat anterior pituitary

scientific article published in February 1985

Kallikrein-Related Peptidases in Prostate Cancer: From Molecular Function to Clinical Application

scientific article

Kallikrein-related Peptidase 15 (Prostinogen)

scientific article published in 2013

Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?

scientific article published on June 2006

Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphisms in ovarian cancer survival

scientific article published on May 2010

Kallikrein-related peptidase 3 (KLK3/PSA) single nucleotide polymorphisms and ovarian cancer survival

scientific article published in August 2011

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression

scientific article

Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

scientific article

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma

scientific article published on 23 March 2010

Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer

scientific article published on 05 October 2018

Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer

scientific article published on 06 September 2018

Kallikreins and kinins in inflammatory-like events in the reproductive tract

scientific article published on June 1997

Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus

scientific article published on 26 January 2010

Localization of arginine vasopressin-neurophysin II messenger ribonucleic acid in the hypothalamus of control and Brattleboro rats by hybridization histochemistry with a synthetic pentadecamer oligonucleotide probe

scientific article published in June 1985

Long terminal repeats act as androgen-responsive enhancers for the PSA-kallikrein locus

scientific article published on 17 May 2012

Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load

scientific article

Lycopene's Effects on Cancer Cell Functions within Monolayer and Spheroid Cultures

scientific article published on 25 March 2016

MOLECULAR DETECTION OF PROSTATE CELLS IN EJACULATE AND URETHRAL WASHINGS IN MEN WITH SUSPECTED PROSTATE CANCER

scientific article published on 01 April 1999

Mass spectrometry based proteomics analyses in kallikrein-related peptidase research: implications for cancer research and therapy

scientific article

Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency.

scientific article

Metastasis of ovarian cancer is mediated by kallikrein related peptidases

scientific article published on 17 September 2013

MicroRNA Theranostics in Prostate Cancer Precision Medicine

scientific article published on 18 August 2016

MicroRNA-3162-5p-Mediated Crosstalk between Kallikrein Family Members Including Prostate-Specific Antigen in Prostate Cancer

scientific article published on 24 April 2019

Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts

scientific article published on 31 July 2019

Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment

scientific article published on 5 August 2010

Mining human cancer datasets for kallikrein expression in cancer: the ‘KLK-CANMAP’ Shiny web tool

scientific article published on 01 September 2018

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

scientific article published on 29 May 2015

Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer.

scientific article published on 24 February 2015

N-acetylated endorphins in ovine anterior pituitary and neuro-intermediate lobe

scientific article

Naloxone, Adrenalectomy, and Steroid Replacement:Evidence against a Role for Circulating β-Endorphin in Food Intake*

scientific article published on 01 January 1981

Oestrogen administration and the expression of the kallikrein gene family in the rat submandibular gland

article

Opiate binding sites in bovine adrenal medulla

scientific article published in January 1983

PITX2 and non-canonical Wnt pathway interaction in metastatic prostate cancer.

scientific article published on 26 October 2013

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility

scientific article published on 6 December 2006

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

scientific article

Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis

scientific article published on 12 February 2014

Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases

scientific article published in November 2017

Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment

scientific article

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

scientific article published on 10 January 2018

Post-GWAS in prostate cancer: from genetic association to biological contribution

scientific article published on 01 January 2019

Post-Translational Processing of Pro-Opiomelanocortin in the Brattleboro (di/di) Rat Pituitary

scientific article published on 01 December 1988

Prediction of individual genetic risk to prostate cancer using a polygenic score

scientific article published on 14 July 2015

Preface to "Proteases in Cancer Progression and Metastasis" special issue

scientific article published on 01 September 2019

Pro-opiomelanocortin (POMC) gene expression, as identified by in situ hybridization, in purified populations of interstitial macrophages and Leydig cells of the adult rat testis

article

Production and characterization of antipeptide kallikrein 4 antibodies. Use of computer modeling to design peptides specific to Kallikrein 4

scientific article published on 01 January 2003

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function

scientific article published on 11 December 2018

Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1.

scientific article published on 5 July 2016

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs).

scientific article published on June 2008

Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer

scientific article published on 11 May 2014

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Rapid and specific lowering of pituitary FSH beta mRNA levels by inhibin

scientific article published in October 1987

Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells

scientific article

Realizing the Potential of Ejaculate/Seminal Fluid in Detecting and Predicting Natural History

scientific article published on January 1, 2003

Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?

scientific article published on December 2008

Regulation of follicle-stimulating hormone beta and common alpha-subunit messenger ribonucleic acid by gonadotropin-releasing hormone and estrogen in the sheep pituitary.

scientific article published in September 1989

Regulation of liver angiotensinogen mRNA by glucocorticoids and thyroxine

scientific article published on 01 February 1989

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

scientific article published on 2 April 2015

Secretome and degradome profiling shows that Kallikrein-related peptidases 4, 5, 6, and 7 induce TGFβ-1 signaling in ovarian cancer cells

scientific article published on October 2013

Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum

scientific article published on 30 September 2016

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

scientific article published on 30 April 2012

Seminal fluid characterization for male fertility and prostate cancer: kallikrein-related serine proteases and whole proteome approaches

scientific article published on February 2007

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

scientific article

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Simplified Radioimmunoassay for Serum Aldosterone Utilizing Increased Antibody Specificity

scientific article published on 01 April 1974

Single Nucleotide Polymorphisms (SNPs)

scientific article published in 2014

Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?

scientific article published on 23 September 2015

Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone

scientific article published on 16 February 2014

Standard PREanalytical Code version 3.0.

scientific article published on 29 January 2018

Standard preanalytical coding for biospecimens: review and implementation of the Sample PREanalytical Code (SPREC).

scientific article published on August 2012

Stress, dopaminergic blockade and median eminence-neurointermediate lobe catecholamine depletion: effects on hypothalamic, pituitary and plasma immunoreactive beta-endorphin

scientific article published in May 1984

Studies on human sexual development. III. Fetal pituitary and serum, and amniotic fluid concentrations of LH, CG, and FSH.

scientific article published in January 1976

Studies on human sexual development. IV. Fetal pituitary and serum, and amniotic fluid concentrations of prolactin

scientific article published in February 1977

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

scientific article

TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma

scientific journal article

Temporal and Tissue-Specific Expression of Kallikrein (Klk) Genes and Identification of a Novel Klk Messenger Ribonucleic Acid Transcript during Early Development in the Mouse1

scientific article published on 01 September 1999

The Expression of the Kallikrein Gene Family in the Rat Pituitary: Oestrogen Effects and the Expression of an Additional Family Member in the Neurointermediate Lobe

article

The Human Tissue Kallikrein and Kallikrein-related Peptidase Family

scientific article published in 2013

The Molecular Biology of the Kallikreins and their Roles in Inflammation

scientific article published in 1997

The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration

scientific article published on 7 February 2012

The effect of sample size on polygenic hazard models for prostate cancer

scientific article published on 08 June 2020

The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions

scientific article (publication date: 2001)

The human tissue kallikreins (KLKs 1-3) and a novel KLK1 mRNA transcript are expressed in a renal cell carcinoma cDNA library.

scientific article

The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness

scientific article

The kallikrein-related peptidase family: Dysregulation and functions during cancer progression.

scientific article published on 03 September 2015

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer

scientific article published on 28 November 2019

The potential role of lycopene for the prevention and therapy of prostate cancer: from molecular mechanisms to clinical evidence

scientific article published on 12 July 2013

The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition

scientific article published on June 2006

The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers

scientific article published in January 2004

The use of predictive or prognostic genetic biomarkers in endometrial and other hormone-related cancers: justification for extensive candidate gene single nucleotide polymorphism studies of the matrix metalloproteinase family and their inhibitors

scientific article published on September 2009

Tie-2 regulates the stemness and metastatic properties of prostate cancer cells.

scientific article published on 29 April 2015

Tissue Kallikrein-Kinin System

scientific article published in January 2011

Tissue engineered humanized bone supports human hematopoiesis in vivo

scientific article

Tissue kallikrein and the bradykinin B2 receptor are expressed in endometrial and prostate cancers

scientific article published on 01 June 1997

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function

scientific article published in February 2008

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

scientific article published in January 2021

Transforming the Future of Treatment for Ovarian Cancer

scientific article published in 2014

Translating tissue engineering technology platforms into cancer research

scientific article published on 20 July 2009

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

scientific article (publication date: 12 January 2001)

Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures.

scientific article

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