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List of works by Colleen Nelson

6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.

scientific article published on 19 October 2016

A Collective Route to Head and Neck Cancer Metastasis

scientific article published on 15 January 2018

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease

scientific article published on 24 January 2012

A liquid biopsy for head and neck cancers.

scientific article

A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness

scientific article published on 4 December 2017

A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome

scientific article published on 07 September 2018

A mutant P53 can activate apoptosis through a mechanism distinct from those induced by wild type P53

scientific article published on 01 April 2002

A novel communication role for CYP17A1 in the progression of castration-resistant prostate cancer

scientific article published on June 2009

A variant of the KLK4 gene is expressed as a cis sense-antisense chimeric transcript in prostate cancer cells

scientific article published on 20 April 2010

Acrylamide capture of DNA-bound complexes: electrophoretic purification of transcription factors

scientific article published in April 2002

Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop

scientific article published on 17 December 2015

Adiponectin receptor activation inhibits prostate cancer xenograft growth

scientific article published on 01 October 2020

Adverse effects of androgen-deprivation therapy in prostate cancer and their management

scientific article

Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.

scientific article

Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model

scientific article published in March 2010

Analysis of androgen and anti-androgen regulation of KLK-related peptidase 2, 3, and 4 alternative transcripts in prostate cancer

scientific article published on September 2014

Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer

scientific article

Androgen receptor and nutrient signaling pathways coordinate increased amino acid transport in prostate cancer progression.

scientific article published in June 2012

Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.

scientific article published on 17 October 2011

Androgen responsiveness of Renilla luciferase reporter vectors is promoter, transgene, and cell line dependent

scientific article published on May 2004

Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT)

scientific article

Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

scientific article

Androgen-targeted therapy-induced epithelial mesenchymal plasticity and neuroendocrine transdifferentiation in prostate cancer: an opportunity for intervention

scientific article published in 2014

Antiproliferative mechanisms of the flavonoids 2,2'-dihydroxychalcone and fisetin in human prostate cancer cells

scientific article published on January 2010

Application of Gene Microarrays in the Study of Prostate Cancer

scientific article published on January 1, 2003

Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance

scientific article published on February 2010

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

scientific article published on 27 April 2016

Biomarker and translational prostate cancer research.

scientific article published on 15 January 2015

Circulating tumour cells in metastatic head and neck cancers

scientific article

Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer.

scientific article

Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cells

scientific article

Clusterin is a critical downstream mediator of stress-induced YB-1 transactivation in prostate cancer

scientific article published on 10 October 2011

Comprehensive expression analysis of L-dopa decarboxylase and established neuroendocrine markers in neoadjuvant hormone-treated versus varying Gleason grade prostate tumors

scientific article published on 25 September 2006

Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity

scientific article published on November 2007

Correction: A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome

scientific article published on 01 March 2019

Correction: Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment.

scientific article published on 17 January 2013

Cytotoxic C20 Diterpenoid Alkaloids from the Australian Endemic Rainforest Plant Anopterus macleayanus

scientific article published on 24 November 2015

Demonstration of upregulated H2 relaxin mRNA expression during neuroendocrine differentiation of LNCaP prostate cancer cells and production of biologically active mammalian recombinant 6 histidine-tagged H2 relaxin

scientific article published on May 2005

Denhaminols A-H, dihydro-β-agarofurans from the endemic Australian rainforest plant Denhamia celastroides. ⬇️

scientific article

Design and Synthesis of a Screening Library Using the Natural Product Scaffold 3-Chloro-4-hydroxyphenylacetic Acid

scientific article published on 24 March 2015

Design, synthesis and spectroscopic characterisation of a focused library based on the polyandrocarpamine natural product scaffold

scientific article

Differential effects of tissue culture coating substrates on prostate cancer cell adherence, morphology and behavior

scientific article

Differential regulation of IGFBP-3 by the androgen receptor in the lineage-related androgen-dependent LNCaP and androgen-independent C4-2 prostate cancer models

scientific article published on June 2006

Differential regulation of clusterin and its isoforms by androgens in prostate cells

scientific article published on 4 December 2006

Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells.

scientific article

Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence

scientific article published in March 2004

Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells

scientific article

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment

scientific article published on 25 April 2019

Enrichment of circulating head and neck tumour cells using spiral microfluidic technology.

scientific article published on 15 February 2017

Erratum to: Fusion transcript loci share many genomic features with non-fusion loci.

scientific article published on 3 June 2016

Exosomes in prostate cancer: putting together the pieces of a puzzle

scientific article

Extracellular Vesicles in the Adaptive Process of Prostate Cancer during Inhibition of Androgen Receptor Signaling by Enzalutamide.

scientific article

Extracellular vesicles for personalized therapy decision support in advanced metastatic cancers and its potential impact for prostate cancer

scientific article published on 29 August 2017

Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis

scientific article (publication date: 28 August 2003)

Fusion transcript loci share many genomic features with non-fusion loci

scientific article published in December 2015

Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population.

scientific article published on May 2011

Heterogeneity of miR-10b expression in circulating tumor cells

scientific article

IGF2 increases de novo steroidogenesis in prostate cancer cells

scientific article published on 22 March 2013

Identification and characterization of a prostate-specific androgen-independent protein-binding site in the probasin promoter

scientific article

Identification of Gibberellic Acid Derivatives That Deregulate Cholesterol Metabolism in Prostate Cancer Cells.

scientific article published on 23 February 2018

Identification of a novel fusion transcript between human relaxin-1 (RLN1) and human relaxin-2 (RLN2) in prostate cancer

scientific article published on 20 October 2015

Identification of eusynstyelamide B as a potent cell cycle inhibitor following the generation and screening of an ascidian-derived extract library using a real time cell analyzer.

scientific article published on 17 October 2014

Impact of label-free technologies in head and neck cancer circulating tumour cells.

scientific article published on 16 September 2016

In vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors.

scientific article

Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis

scientific article published on December 2005

Insights from engraftable immunodeficient mouse models of hyperinsulinaemia.

scientific article

Insulin Enhances Migration and Invasion in Prostate Cancer Cells by Up-Regulation of FOXC2

scientific article published on 17 July 2019

Insulin Increases De Novo Steroidogenesis in Prostate Cancer Cells

scientific article published on 11 July 2011

Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer

scientific article published on September 2014

Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?

scientific article

Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model

scientific article published on July 2010

Intraprostatic Steroidogenic Enzymes – Letter ⬇️

scientific article published on October 12, 2010

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

scientific article published on 01 May 2007

Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system

scientific article

Isolation, structure determination and cytotoxicity studies of tryptophan alkaloids from an Australian marine sponge Hyrtios sp. ⬇️

scientific article

J-Circos: an interactive Circos plotter

scientific article published on 24 December 2014

Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys]-GHRP-6

article

Lipid Uptake Is an Androgen-Enhanced Lipid Supply Pathway Associated with Prostate Cancer Disease Progression and Bone Metastasis

scientific article published on 26 February 2019

Mechanisms of the development of androgen independence in prostate cancer

scientific article

Mining human cancer datasets for kallikrein expression in cancer: the ‘KLK-CANMAP’ Shiny web tool

scientific article published on 01 September 2018

Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer

scientific article published on 8 August 2016

Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation

scientific article published on 25 January 2022

New players for advanced prostate cancer and the rationalisation of insulin-sensitising medication

scientific article published on 19 March 2013

No effect of administration of unacylated ghrelin on subcutaneous PC3 xenograft growth in a Rag1-/- mouse model of metabolic dysfunction

No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1-/- mouse model of metabolic dysfunction

scientific article published in PLoS ONE

P-glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cells

scientific article (publication date: April 2004)

PD-L1 expressing circulating tumour cells in head and neck cancers.

scientific article

Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis

scientific article published on 12 February 2014

Personalized Cancer Therapy for Urological Cancers: From Bench to Bedside and Back ⬇️

scientific article published on September 12, 2012

Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment

scientific article

Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding

scientific article published in March 2002

Probasin promoter assembles into a strongly positioned nucleosome that permits androgen receptor binding

scientific article published on 23 January 2007

Prostate-tumor targeting of gene expression by lentiviral vectors containing elements of the probasin promoter

scientific article

RNASeqBrowser: a genome browser for simultaneous visualization of raw strand specific RNAseq reads and UCSC genome browser custom tracks

scientific article published on March 2015

RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor

scientific article (publication date: 13 December 2002)

Receptor-DNA interactions: EMSA and footprinting

scientific article published in January 2009

Relaxin becomes upregulated during prostate cancer progression to androgen independence and is negatively regulated by androgens

scientific article published on December 2006

Relaxin drives Wnt signaling through upregulation of PCDHY in prostate cancer

scientific article

Relaxin stimulates leukocyte adhesion and migration through a relaxin receptor LGR7-dependent mechanism

scientific article published on 22 November 2005

Repositioning "old" drugs for new causes: identifying new inhibitors of prostate cancer cell migration and invasion

scientific article

Seed-based biclustering of gene expression data

scientific article

Short term ex-vivo expansion of circulating head and neck tumour cells.

scientific article

Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro

scientific article published on 28 July 2006

Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts

scientific article

Synthesis of a Unique Psammaplysin F Library and Functional Evaluation in Prostate Cancer Cells by Multiparametric Quantitative Single Cell Imaging

scientific article published on 21 July 2020

Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

scientific article published on 07 May 2020

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

scientific article

Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development

scientific article

The Emerging Role of Extracellular Vesicle-Mediated Drug Resistance in Cancers: Implications in Advanced Prostate Cancer

scientific article published on 26 October 2015

The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer

scientific article published on 3 April 2012

The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli

scientific article published on 20 February 2002

The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells

scientific article published on December 2015

The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer

scientific article published on October 2014

The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion

scientific article published in August 2003

The long non-coding RNA GHSROS facilitates breast cancer cell migration and orthotopic xenograft tumour growth

scientific article published on 04 October 2019

The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype

scientific article published on 01 February 2021

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer

scientific article published on 28 November 2019

The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells

scientific article published on 22 March 2015

Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance

scientific article

Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer

scientific article published on 19 June 2020

Timing is everything: preclinical evidence supporting simultaneous rather than sequential chemohormonal therapy for prostate cancer

scientific article published on July 2005

Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination

scientific article published on 24 July 2018

Transient Sox9 Expression Facilitates Resistance to Androgen-Targeted Therapy in Prostate Cancer

scientific article published on 09 January 2020

Using prostate specific membrane antigen (PSMA) expression in clear cell renal cell carcinoma for imaging advanced disease

scientific article published on 24 August 2016

Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.

scientific article published on 16 April 2017

YB-1 is upregulated during prostate cancer tumor progression and increases P-glycoprotein activity

scientific article published on May 2004

miRDeep*: an integrated application tool for miRNA identification from RNA sequencing data ⬇️

scientific article published on December 4, 2012

miRPlant: an integrated tool for identification of plant miRNA from RNA sequencing data

scientific article

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