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List of works by Carola Garcia de Vinuesa

A BATF-ling connection between B cells and follicular helper T cells

scientific article published on 01 June 2011

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

scientific article published on 21 October 2019

Analysis of B cell memory formation using DNA microarrays.

scientific article published in December 2002

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells

scientific article

Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation

scientific article

Atypical chemokine receptor 4 shapes activated B cell fate.

scientific article published on 31 January 2018

Author Correction: A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

scientific article published on 20 November 2019

Axon growth and guidance genes identify T-dependent germinal centre B cells

scientific article published on 16 October 2007

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

scientific article

Blood Relatives of Follicular Helper T Cells ⬇️

scientific article published on January 28, 2011

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells

scientific article

Brief Report: Identification of a Pathogenic Variant in TREX1 in Early-Onset Cerebral Systemic Lupus Erythematosus by Whole-Exome Sequencing

scientific article published on 01 December 2014

Cellular and genetic mechanisms of self tolerance and autoimmunity

scientific article

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

scientific article published on October 2013

Class-Switch Recombination Occurs Infrequently in Germinal Centers

scientific article published on 30 July 2019

Control of TFH cell numbers: why and how?

scientific article

DNA drives autoimmunity

scientific article published in Nature

Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses.

scientific article

Detection of mouse natural killer T follicular helper (NKT(FH)) cells by flow cytometry.

scientific article published on January 2015

Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity.

scientific article

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

scientific article published in June 2016

Dysregulation of germinal centres in autoimmune disease.

scientific article published on December 2009

Dysregulation of immune homeostasis in autoimmune diseases

scientific article published on 06 January 2012

Enhanced antiviral antibody secretion and attenuated immunopathology during influenza virus infection in nitric oxide synthase-2-deficient mice

scientific article published in November 2006

Erratum: Corrigendum: Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

article

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

scientific article published on 01 January 2010

Extrafollicular antibody responses

scientific article

Follicular Helper T Cells

scientific article

Follicular helper T cells are required for systemic autoimmunity

scientific article published on 16 February 2009

Foxp3+ follicular regulatory T cells control the germinal center response.

scientific article

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

scientific article published on 17 May 2019

Gain-of-function mutation causes human combined immune deficiency

scientific article published on 18 October 2018

Genomic test ends a long diagnostic odyssey in a patient with resistance to thyroid hormones

scientific article published on 15 July 2019

Germinal Center Lymphocyte Ratios and Successful HIV Vaccines.

scientific article published on 11 January 2017

HIV Immunogens: Affinity Is Key.

scientific article published in January 2018

HIV and T follicular helper cells: a dangerous relationship ⬇️

scientific article published on August 27, 2012

Heterozygosity for Roquinsan leads to angioimmunoblastic T-cell lymphoma-like tumors in mice

scientific article published on 13 June 2012

How T Cells Earn the Follicular Rite of Passage ⬇️

scientific article published on November 23, 2011

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

scientific article published on 12 September 2013

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

scientific article

IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice

scientific article published on 12 September 2016

Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

scientific article

Immunodeficiency and Abnormal B Cell Synapse Formation due to DOCK8 Mutations in Mice

scholarly article by Katrina Randall et al published January 2010 in Clinical Immunology

Inflammation: gone with translation.

scientific article

Innate B cell helpers reveal novel types of antibody responses.

scientific article published on 18 January 2013

Innate virus-sensing pathways in B cell systemic autoimmunity

scientific article published on 04 May 2023

Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers

scientific article published on 01 November 2012

Logic and extent of miRNA-mediated control of autoimmune gene expression

scientific article

Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

scientific article published on February 2002

MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres

scientific article

Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation

scientific article

Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity

scientific article published on 05 April 2010

New territory for T follicular helper cells

scientific article published in September 2013

Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders

scientific article published on 11 September 2019

Pathophysiology of T follicular helper cells in humans and mice

scientific article published on February 2015

Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center.

scientific article published on May 2017

Posttranscriptional T cell gene regulation to limit Tfh cells and autoimmunity.

scientific article published on 29 September 2015

ROQUIN signalling pathways in innate and adaptive immunity

scientific article published on 6 April 2016

Recirculating and germinal center B cells differentiate into cells responsive to polysaccharide antigens

scientific article published on 01 February 2003

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

scientific journal article

Regulatory roles of IL-10-producing human follicular T cells

scientific article published on 17 June 2019

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis

scientific journal article

Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation

scientific article

STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles

scientific article published on 23 February 2018

SiLEncing SLE: the power and promise of small noncoding RNAs.

scientific article published on September 2008

Signals that influence T follicular helper cell differentiation and function.

scientific article published on 27 January 2010

Synaptic Interactions in Germinal Centers

scientific article published on 13 August 2018

Systemic lupus erythematosus: A new autoimmune disorder in Kabuki syndrome

scientific article published on 11 September 2018

T Follicular Helper Cells in Transplantation.

scientific article published on 29 June 2016

T cells and follicular dendritic cells in germinal center B-cell formation and selection.

scientific article published on September 2010

T follicular helper cells during immunity and tolerance.

scientific article published on January 2010

T-cell subsets in the germinal center.

scientific article

T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells.

scientific article published on May 2012

TFH-derived dopamine accelerates productive synapses in germinal centres.

scientific article published on 12 July 2017

TLR7 gain-of-function genetic variation causes human lupus

scientific article published on 27 April 2022

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs

scientific article

The elusive identity of T follicular helper cells ⬇️

scientific article published on August 31, 2010

The molecular basis of lymphoid architecture and B cell responses: implications for immunodeficiency and immunopathology.

scientific article

The transcription factor ZEB2 drives the formation of age-associated B cells

scientific article published on 25 January 2024

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment

scientific article published on 23 July 2009

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

scientific article

Tolerance mechanisms in the late phase of the antibody response

scientific article published on January 2007

Tracking the response of Xid B cells in vivo: TI-2 antigen induces migration and proliferation but Btk is essential for terminal differentiation

scientific article published in May 2001

Two levels of protection for the B cell genome during somatic hypermutation.

scientific article

Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi.

scientific article published on 21 November 2017

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