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List of works by Aleksandra Filipovska

1 : 2 Adducts of copper(I) halides with 1,2-bis(di-2-pyridylphosphino)ethane: solid state and solution structural studies and antitumour activity.

scientific article

A bifunctional protein regulates mitochondrial protein synthesis

scientific article (publication date: May 2014)

A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance

scientific article published on 24 September 2021

A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

scientific article published on 21 July 2007

A modified yeast three-hybrid system enabling both positive and negative selections

scientific article published on 18 May 2018

A mutation in MT-TW causes a tRNA processing defect and reduced mitochondrial function in a family with Leigh syndrome.

scientific article published on 30 October 2015

A universal code for RNA recognition by PUF proteins

scientific article

Adult-onset obesity is triggered by impaired mitochondrial gene expression.

scientific article published on 16 August 2017

Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

scientific article

An Artificial Yeast Genetic Circuit Enables Deep Mutational Scanning of an Antimicrobial Resistance Protein

scientific article published on 17 July 2018

An artificial PPR scaffold for programmable RNA recognition

scientific article

Analysis of the human mitochondrial transcriptome using directional deep sequencing and parallel analysis of RNA ends.

scientific article published in January 2014

Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome

scientific article published on August 2017

Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome.

scientific article

Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound

scientific article

Building a Parallel Metabolism within the Cell

scientific article published on 4 January 2008

Building artificial genetic circuits to understand protein function

scientific article published on 22 November 2019

Ca(v)1.2 calcium channel is glutathionylated during oxidative stress in guinea pig and ischemic human heart

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

scientific article published on 23 June 2020

Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers.

scientific article published on November 2004

CirGO: an alternative circular way of visualising gene ontology terms

article

Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage

scientific article published on 8 July 2008

Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z

scientific article published on 20 August 2018

Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes

scientific article

Defects in RNA metabolism in mitochondrial disease

scientific article published on 8 February 2017

Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation.

scientific article published on January 2004

Designer RNA-binding proteins: New tools for manipulating the transcriptome ⬇️

scientific article published on November 1, 2011

Dinuclear Au(i) N-heterocyclic carbene complexes derived from unsymmetrical azolium cyclophane salts: potential probes for live cell imaging applications.

scientific article published in July 2016

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

scientific article published on 03 October 2019

Disulphide formation on mitochondrial protein thiols.

scientific article

Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction

scientific article published on 05 October 2018

Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network

scientific article published on 20 November 2019

Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation

scientific article published on 27 December 2012

Estrogen-mediated regulation of mitochondrial gene expression.

scientific article

Expression patterns of regulatory RNAs, including lncRNAs and tRNAs, during postnatal growth of normal and dystrophic (mdx) mouse muscles, and their response to taurine treatment

scientific article published on 22 March 2018

Fidelity and coordination of mitochondrial protein synthesis in health and disease

scientific article published on 25 July 2020

Fidelity of translation initiation is required for coordinated respiratory complex assembly

scientific article published on 20 December 2019

Founder p.Arg 446* mutation in the PDHX gene explains over half of cases with congenital lactic acidosis in Roma children.

scientific article published on 21 July 2014

Glutathionylation of mitochondrial proteins

scientific article

Gold compounds as therapeutic agents for human diseases

scientific article (publication date: September 2011)

Gold(I) chloride adducts of 1,3-bis(di-2-pyridylphosphino)propane: synthesis, structural studies and antitumour activity

scientific article

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016

Impaired functional communication between the L-type calcium channel and mitochondria contributes to metabolic inhibition in the mdx heart

scientific article

Investigating Mitochondrial Transcriptomes and RNA Processing Using Circular RNA Sequencing

scientific article published on 01 January 2021

Is mitochondrial gene expression coordinated or stochastic?

article

L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte

scientific article published on 18 January 2013

LRPPRC-mediated folding of the mitochondrial transcriptome

scientific article published on 16 November 2017

Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology.

scientific article

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

scientific article published on 25 October 2011

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice

scientific article

MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins.

scientific article

Manipulating and elucidating mitochondrial gene expression with engineered proteins

scientific article published on 02 December 2019

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

scientific article published on 31 October 2013

Measurement of protein glutathionylation

scientific article published on 01 June 2006

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

scientific article published on 23 March 2018

Mitochondria-targeted antioxidants in the treatment of disease

scientific article published on December 2008

Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.

scientific article

Mitochondria: Unusual features of the mammalian mitoribosome

scientific article published on 16 May 2014

Modular recognition of nucleic acids by PUF, TALE and PPR proteins ⬇️

scientific article published on January 10, 2012

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

scientific article published on 7 June 2018

Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer

scientific article published on 04 June 2019

Molecular basis of translation termination at noncanonical stop codons in human mitochondria

scientific article published on 04 May 2023

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

scientific article published on 04 March 2020

Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction

scientific journal article

OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data

scientific article published on 22 January 2021

Organelle transcriptomes: products of a deconstructed genome

scientific article published on 07 August 2013

Overview of protein glutathionylation

scientific article published on June 2006

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

scientific article published on 05 August 2016

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.

scientific article published in April 2018

Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells

scientific article

Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation

scientific article

Pentatricopeptide repeats: modular blocks for building RNA-binding proteins

scientific article published on 23 April 2013

Preventative therapeutic approaches for hypertrophic cardiomyopathy

scientific article published on 21 August 2020

Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia

scientific article published on 4 October 2011

RNA processing in human mitochondria

scientific article

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

scientific article

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

article

Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping

scientific article published on 26 February 2013

Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation

scientific article published on 06 October 2020

Regulation of a minimal transcriptome by repeat domain proteins.

scientific article published on 23 August 2017

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin

scientific article published on 25 May 2009

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

scientific article published on 6 August 2015

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

scientific article published on 23 November 2017

Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing

scientific article

Specialization from synthesis: How ribosome diversity can customize protein function ⬇️

scientific article published on February 26, 2013

Stepwise maturation of the peptidyl transferase region of human mitoribosomes

scientific article published on 16 June 2021

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

scientific article published on 13 November 2019

Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

scientific article

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

scientific article published on 21 December 2010

Supernumerary proteins of mitochondrial ribosomes.

scientific article published on 17 August 2013

Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

scientific article published on 14 April 2005

TEFM regulates both transcription elongation and RNA processing in mitochondria.

scientific article

The First Mitochondrial Genomics and Evolution SMBE-Satellite Meeting: A New Scientific Symbiosis

scientific article

The L-type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy.

scientific article

The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy

scientific article published on 01 January 2016

The human mitochondrial transcriptome

scientific article

The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression

scientific article

The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication

The role of mammalian PPR domain proteins in the regulation of mitochondrial gene expression

scientific article published on 26 October 2011

Tighter Ligand Binding Can Compensate for Impaired Stability of an RNA-Binding Protein

scientific article published on 29 May 2018

Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

scientific article published on 9 August 2016

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

scientific article published on 14 November 2017

Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM

scientific article published in Nature

Using mitochondria-targeted molecules to study mitochondrial radical production and its consequences.

scientific article published in December 2003

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