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List of works by James Henderson Naismith

A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa

scientific article published on 22 August 2018

A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA

scientific article published on 9 November 2015

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

scientific article published on 05 February 2016

A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide

scientific article published on 15 December 2014

A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication

scientific article published on 10 November 2010

A flavin-dependent tryptophan 6-halogenase and its use in modification of pyrrolnitrin biosynthesis

A localized tolerance in the substrate specificity of the fluorinase enzyme enables "last-step" 18F fluorination of a RGD peptide under ambient aqueous conditions.

scientific article published on 2 July 2014

A marine viral halogenase that iodinates diverse substrates

scientific article published on 14 October 2019

A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus

scientific article

A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds

scientific article published on 24 August 2018

A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model

scientific article

A novel outer membrane protein, Wzi, is involved in surface assembly of the Escherichia coli K30 group 1 capsule

scientific article

A simple and efficient expression and purification system using two newly constructed vectors

scientific article published on 20 September 2008

A snapshot of carnitine acetyltransferase

scientific article

A structural perspective on the enzymes that convert dTDP-d-glucose into dTDP-l-rhamnose

scientific article

Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR.

scientific article published on 11 February 2016

Accurate quantification of modified cyclic peptides without the need for authentic standards

scientific article published on 16 November 2016

AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

scientific article

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System. ⬇️

scientific article published on 28 June 2017

Adenylate-forming enzymes

scientific article

Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa

scientific article

Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli

scientific article published in 2011

An efficient method for the in vitro production of azol(in)e-based cyclic peptides.

scientific article published on 21 October 2014

An enzymatic route to selenazolines

scientific article

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 15 October 2020

Bacterial mechanosensitive channels--MscS: evolution's solution to creating sensitivity in function

scientific article published on 23 February 2012

Bacterial polysaccharide synthesis and export

scientific article

Biological Fluorination in Streptomyces cattleya

Bypassing the proline/thiazoline requirement of the macrocyclase PatG.

scientific article published in November 2017

CRISPR interference: a structural perspective

scientific article

Catalytic and Anticatalytic Snapshots of a Short-Form ATP Phosphoribosyltransferase

Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis

scientific article

Chapter 11 Bacterial Membrane Proteins

Characterization and crystal structure of Escherichia coli KDPGal aldolase

scientific article

Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates

scientific article published on 29 January 2018

Chemical insights from structural studies of enzymes

scientific article

Chemical synthesis of UDP-Glc-2,3-diNAcA, a key intermediate in cell surface polysaccharide biosynthesis in the human respiratory pathogens B. pertussis and P. aeruginosa.

scientific article published on 2 February 2009

Chemistry's prodigal child: enzyme mechanism

Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa

scientific article published on 11 January 2019

Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy

scientific article

Corrigendum: A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

scientific article published on 01 January 2017

Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly

scientific article

Crystal structure and mechanism of a bacterial fluorinating enzyme

scientific article

Crystal structure and silica condensing activities of silicatein α–cathepsin L chimeras

scientific article

Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: implications for angiogenic regulation

scientific article

Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state

scientific article published on May 2005

Crystallization and X-ray diffraction of 5'-fluoro-5'-deoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya

scientific article

Crystallization and X-ray diffraction of a halogenating enzyme, tryptophan 7-halogenase, from Pseudomonas fluorescens

scientific article

Crystallization and preliminary X-ray diffraction analysis of Wza outer-membrane lipoprotein from Escherichia coli serotype O9a:K30.

scientific article published on 25 February 2004

Crystallization and preliminary crystallographic analysis of the bacterial capsule assembly-regulating tyrosine phosphatases Wzb of Escherichia coli and Cps4B of Streptococcus pneumoniae

scientific article

Crystallization and preliminary diffraction analysis of Wzi, a member of the capsule export and assembly pathway in Escherichia coli

scientific article

Crystallization of Ranasmurfin, a blue-coloured protein from Polypedates leucomystax.

scientific article

Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis

scientific article published on 01 September 1998

Crystallization, dehydration and experimental phasing of WbdD, a bifunctional kinase and methyltransferase fromEscherichia coliO9a

scientific article

Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor

scientific article

Derivatisable Cyanobactin Analogues: A Semisynthetic Approach

scientific article published on 28 October 2015

Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC.

scientific article published in June 2018

Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli

scientific article

Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

scientific article

Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales

scientific article

Editorial overview: Catalysis and regulation: enzyme catalysis, biosynthetic pathways and regulation

scientific article published on 2 December 2014

Engineering Thermostability in Artificial Metalloenzymes to Increase Catalytic Activity

scientific article published in 2021

Enhanced imaging of lipid rich nanoparticles embedded in methylcellulose films for transmission electron microscopy using mixtures of heavy metals ⬇️

scientific article published on 10 April 2017

Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics

scientific article

Epimerases: structure, function and mechanism

scientific article

Exploration of a potential difluoromethyl-nucleoside substrate with the fluorinase enzyme

scientific article

Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase

scientific article

Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance

scientific article

Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins

scientific article published on 17 August 2018

Halomethane Biosynthesis: Structure of a SAM-Dependent Halide Methyltransferase from Arabidopsis thaliana

scientific article

High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme

scientific article

High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A.

scientific article published in September 1994

Hydrolase and sialyltransferase activities of trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-gal-Gal-beta-O-PNP.

scientific article

Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations

scientific article published on 19 July 2019

Identification of conserved residues contributing to the activities of adenovirus DNA polymerase

scientific article published on December 2000

Identification of fluorinases from streptomyces sp MA37, norcardia brasiliensis, and actinoplanes sp N902-109 by genome mining

scientific article

Inferring the chemical mechanism from structures of enzymes

scientific article published on 18 May 2006

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation

scientific article

Initiating a crystallographic study of UDP-galactopyranose mutase from Escherichia coli

article

Initiating a crystallographic study of UDP-galactopyranose mutase fromEscherichia coli. Erratum

article

Initiating a crystallographic study of a class II fructose-1,6-bisphosphate aldolase

scientific article published on 01 June 1992

Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli

scientific article published on 01 November 1999

Inside Cover: The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac (Chem. Eur. J. 37/2016)

Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein

scientific article (publication date: 2 June 2003)

Insights into the Mechanism of the Cyanobactin Heterocyclase Enzyme

scientific article published in 2019

Kinetic Landscape of a Peptide Bond-Forming Prolyl Oligopeptidase

scientific article published on 23 March 2017

Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase

scientific article published on 16 January 2017

Low resolution structure of a bacterial SLC26 transporter reveals dimeric stoichiometry and mobile intracellular domains

scientific article

MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded β-Barrel Monomers with a Ca2+ Ion Bound at the Constriction Zone

scientific article

Mechanism of DNA loading by the DNA repair helicase XPD.

scientific article published on 20 February 2016

Mechanism of Enzymatic Fluorination in Streptomyces c attleya

scientific article

Mechanism of the Class I KDPG aldolase

scientific article

Mechanism of ubiquitylation by dimeric RING ligase RNF4

scientific article

Mechanisms of cyanobactin biosynthesis

scientific article published on 14 September 2016

Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

scientific article

Membrane integrity — direct turbidity measurement of filtrate from MF membrane modules at an operating potable water treatment plant

article

Modularity in the TNF-receptor family

scientific article

Molecular Basis of Filtering Carbapenems by Porins from β-Lactam-resistant Clinical Strains of Escherichia coli

scientific article

Molecular placement of experimental electron density: a case study on UDP-galactopyranose mutase

scientific article published on 21 September 2001

MtsslWizard: In Silico Spin-Labeling and Generation of Distance Distributions in PyMOL.

scientific article

NMR spectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond

scientific article

Nanoparticle suspensions enclosed in methylcellulose: a new approach for quantifying nanoparticles in transmission electron microscopy. ⬇️

scientific article

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 13 July 2020

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

scientific article

Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis

scientific article published on 6 October 2003

On the Meaning of Affinity: Cluster Glycoside Effects and Concanavalin A

article

Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum

scientific article

Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein

scientific article

Overexpression, purification, crystallization and data collection of a single-stranded DNA-binding protein from Sulfolobus solfataricus.

scientific article

Overexpression, purification, crystallization and data collection on the Bordetella pertussis wlbD gene product, a putative UDP-GlcNAc 2'-epimerase.

scientific article

Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium.

scientific article

Oxidation of the Cyanobactin Precursor Peptide Is Independent of the Leader Peptide and Operates in a Defined Order

scientific article published in 2018

PELDOR Spectroscopy Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia coli

scientific article

PELDOR in rotationally symmetric homo-oligomers

scientific article published on 30 May 2013

PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis

scientific article published on 01 November 2019

Parakeet: a digital twin software pipeline to assess the impact of experimental parameters on tomographic reconstructions for cryo-electron tomography

scientific article published in 2021

Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides.

scientific article published on 7 May 2018

Periplasmic export machines for outer membrane assembly

scientific article published on 19 May 2008

Periplasmic protein-protein contacts in the inner membrane protein Wzc form a tetrameric complex required for the assembly of Escherichia coli group 1 capsules

scientific article published on 19 September 2005

Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule

scientific article published on 30 June 2016

Pivotal roles of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram-negative bacteria

scientific article published on March 2009

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

scientific article

Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

scientific article published on 02 December 2019

Potentiometric analysis of UDP-galactopyranose mutase: stabilization of the flavosemiquinone by substrate

scientific article published in February 2003

Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen

Preliminary crystallographic characterization of PrnB, the second enzyme in the pyrrolnitrin biosynthetic pathway

scientific article published on 20 October 2006

Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries

scientific article

Probing the structure of the mechanosensitive channel of small conductance in lipid bilayers with pulsed electron-electron double resonance.

scientific article published on February 2014

Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase

scientific article

Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase

scientific article

Purification, crystallization and preliminary crystallographic analysis of WsaF, an essential rhamnosyltransferase from Geobacillus stearothermophilus

scientific article published on 28 November 2008

Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway

scientific article

Purification, crystallization and preliminary structural studies of dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase (RmlC), the third enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar typhimurium

scientific article published in March 1999

Quantification of free cysteines in membrane and soluble proteins using a fluorescent dye and thermal unfolding.

scientific article

Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution

scientific article published in November 1993

Refined structure of concanavalin A complexed with methyl alpha-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure.

scientific article published in November 1994

RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation

scientific journal article

SUMO protease SENP1 induces isomerization of the scissile peptide bond

scientific article

Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in HdeB and May Have a Role in Periplasmic Chaperone Function

scientific article

Spectator no more, the role of the membrane in regulating ion channel function

scientific article published on 7 December 2016

Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme AcsD

scientific article

Structural Basis of Substrate Binding in WsaF, a Rhamnosyltransferase from Geobacillus stearothermophilus

scientific article

Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan

scientific article

Structural analysis of leader peptide binding enables leader-free cyanobactin processing

scientific article

Structural and Functional Characterisation of a Conserved Archaeal RadA Paralog with Antirecombinase Activity

scientific article

Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

scientific article

Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens

scientific article

Structural and mechanistic basis of bacterial sugar nucleotide-modifying enzymes.

scientific article

Structural aspects of non-ribosomal peptide biosynthesis

scientific article

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains

scientific article published on 6 July 2015

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

scientific article published on 31 July 2020

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.

scientific article

Structural basis of trimannoside recognition by concanavalin A

scientific article

Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa

scientific article

Structural, mechanistic and regulatory studies of serine palmitoyltransferase

scientific article published on June 2012

Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii

scientific article published on 30 January 2017

Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity

scientific article

Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site

scientific article published on December 2005

Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis

scientific article

Structure of PatF from Prochloron didemni

scientific article

Structure of WbdD: a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen inEscherichia coliO9a

scientific article

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

scientific article

Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

scientific article

Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains

scientific article

Structure of the DNA Repair Helicase XPD

scientific article

Structure of the archaeal Cascade subunit Csa5

scientific article

Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD

scientific article published on 28 October 2016

Structure of the heterotrimeric PCNA from Sulfolobus solfataricus

scientific article published on 19 September 2006

Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin

scientific article

Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis

scientific article

Structure-function studies of the C3/C5 epimerases and C4 reductases of the Campylobacter jejuni capsular heptose modification pathways

scientific article published on 30 January 2021

Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates

scientific article published on 8 March 2006

Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: fluorinated substrates, kinetics and equilibria.

scientific article published on 23 January 2009

Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization

scientific article (publication date: February 2017)

Synthesis of the natural product descurainolide and cyclic peptides from lignin-derived aromatics

scientific article published on 15 December 2017

Taking a molecular motor for a spin: helicase mechanism studied by spin labeling and PELDOR.

scientific article

TarO: a target optimisation system for structural biology

scientific article

The 1.2 A resolution structure of the Con A-dimannose complex

scientific article

The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli

scholarly article

The AEROPATH project targetingPseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

scientific article

The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility

scientific article published on 11 February 2020

The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac

scientific article published on 08 July 2016

The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction

scientific article

The External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS

scientific article

The Respiratory Arsenite Oxidase: Structure and the Role of Residues Surrounding the Rieske Cluster

scientific article

The Scottish Structural Proteomics Facility: targets, methods and outputs

scientific article

The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway Is Related to the Heme-Dependent Dioxygenase Superfamily †

scientific article

The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway Is Related to the Heme-Dependent Dioxygenase Superfamily,

article published in 2007

The Structure of an Open Form of an E. coli Mechanosensitive Channel at 3.45 A Resolution

scientific article

The chemical basis of serine palmitoyltransferase inhibition by myriocin

scientific article

The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

scientific article published on 14 August 2019

The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold

scientific article

The crystal structure of dTDP-D-Glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-l-rhamnose pathway

scientific article

The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-β-D-mannose suggests a one base mechanism

scientific article

The discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamides

scientific article

The fluorinase from Streptomyces cattleya is also a chlorinase

scientific article

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

scientific article

The molecular basis of regulation of bacterial capsule assembly by Wzc

scientific article published on 16 July 2021

The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme.

scientific article

The purification, crystallization and preliminary structural characterization of glucose-1-phosphate thymidylyltransferase (RmlA), the first enzyme of the dTDP-L-rhamnose synthesis pathway from Pseudomonas aeruginosa

article

The purification, crystallization and structural elucidation of dTDP-D-glucose 4,6-dehydratase (RmlB), the second enzyme of the dTDP-L-rhamnose synthesis pathway from Salmonella enterica serovar typhimurium

scientific article

The rhamnose pathway

scientific article

The role of lipids in mechanosensation

scientific article

The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein

scientific article

The structural basis of chain length control in Rv1086

scientific article

The structural biology of patellamide biosynthesis

scientific article

The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step

scientific article

The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB)

scientific article

The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing

scientific article

The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis

scientific article

The structure of the cyanobactin domain of unknown function from PatG in the patellamide gene cluster

scientific article published on 14 November 2014

The ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamily

scientific article

Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli

scientific article published on 16 April 2004

Toward a structural understanding of the dehydratase mechanism

scientific article

Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza.

scientific article published on 30 September 2003

Trapped translocation intermediates establish the route for export of capsular polysaccharides across Escherichia coli outer membranes

scientific article

Trypanosoma cruzi trypanothione reductase. Crystallization, unit cell dimensions and structure solution.

scientific article

Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination

scientific article

Tryptophan oxygenation: mechanistic considerations ⬇️

scientific article published on June 1, 2012

Tumor Necrosis Factor (TNF)

article from 2002

Two Crystal Forms of the Extracellular Domain of Type I Tumor Necrosis Factor Receptor

Two-step purification of outer membrane proteins

scientific article published on 19 January 2006

Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria

scientific article published on 15 July 2020

Uncovering the chemistry of C-C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex

scientific article published on 09 June 2020

Unraveling the specific regulation of the central pathway for anaerobic degradation of 3-methylbenzoate

scientific article published on 20 March 2015

Unusual Chromophore and Cross-Links in Ranasmurfin: A Blue Protein from the Foam Nests of a Tropical Frog

scientific article

Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters

scientific article published on 17 April 2017

Variation on a Theme of SDR

article

Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein

scientific article

Wzi Is an Outer Membrane Lectin that Underpins Group 1 Capsule Assembly in Escherichia coli

scientific article

YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function

scientific article published on 3 March 2017

Änderung der Regioselektivität der Tryptophan-7-Halogenase PrnA durch ortsspezifische Mutagenese

article

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